Research Topics
| T R ChurchSummaryAffiliation: University of Minnesota Country: USA Publications
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Detail Information
Publications
A school-based strategy to assess children's environmental exposures and related health effects in economically disadvantaged urban neighborhoodsK Sexton
School of Public Health, University of Minnesota, Minneapolis 55455, USA
J Expo Anal Environ Epidemiol 10:682-94. 2000..g., cultural, economic, psychological, social) affecting the willingness of families/children to participate in such studies, with special emphasis on developing cost-effective recruitment methods...- Risk stratification applied to CAST registry data: combining 9 predictors. Cardiac Arrhythmia Suppression TrialTimothy R Church
Division of Environmental and Occupational Health, University of Minnesota School of Public Health, Minneapolis, MN 55455, USA
J Electrocardiol 35:117-22. 2002..With improved component measurements, this approach has the potential for significantly improving risk stratification for the prevention of SCD... - Fecal occult blood screening in the Minnesota study: sensitivity of the screening testT R Church
Division of Environmental and Occupational Health, School of Public Health, University of Minesota, Minneapolis 55455, USA
J Natl Cancer Inst 89:1440-8. 1997..Given these contradictions, we examined screening sensitivity for colorectal cancer in the Minnesota study by several direct and indirect methods... - Risk assessment and risk stratification in sudden cardiac death: a biostatistician's viewT R Church
Division of Environmental and Occupational Health, School of Public Health, University of Minnesota, Minneapolis, USA
Pacing Clin Electrophysiol 20:2520-32. 1997..Multivariate techniques maximize the discrimination of multiple predictors, but may increase complexity. Randomized trials of treatment provide evidence for utility of risk stratification... 
A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokersTimothy R Church
Division of Environmental Health Sciences, University of Minnesota School of Public Health, Minneapolis, Minnesota, USA
Cancer Epidemiol Biomarkers Prev 18:260-6. 2009..Its metabolites, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol and its glucuronides (total NNAL), have been studied as biomarkers of exposure to NNK. We studied the relation of prospectively measured NNK biomarkers to lung cancer risk...- A randomized trial of direct mailing of fecal occult blood tests to increase colorectal cancer screeningTimothy R Church
Division of Environmental and Occupational Health, University of Minnesota, Minneapolis 55455, USA
J Natl Cancer Inst 96:770-80. 2004..We conducted a randomized trial consisting of direct mailing of FOBT kits to increase colorectal cancer screening among residents of Wright County, Minnesota, a community in which colorectal cancer screening was promoted... - Temporal stability of urinary and plasma biomarkers of tobacco smoke exposure among cigarette smokersTimothy R Church
Division of Environmental Health Sciences, University of Minnesota School of Public Health, Minneapolis, MN 55455, USA
Biomarkers 15:345-52. 2010..Except for nicotine, single measurements from plasma or urine adequately represent individual mean exposure over time... - Fecal occult blood screening in the Minnesota study: role of chance detection of lesionsF Ederer
Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, USA
J Natl Cancer Inst 89:1423-8. 1997..This study was conducted to determine how much of the reduction resulted from chance detection... - Children's exposure to environmental tobacco smoke: using diverse exposure metrics to document ethnic/racial differencesKen Sexton
School of Public Health, University of Texas, Brownsville Regional Campus, 80 Fort Brown, RAHC Building, Brownsville, TX 78520, USA
Environ Health Perspect 112:392-7. 2004..73). The results suggest that when children are exposed to ETS primarily in their homes, questionnaires and T-A logs might be effective screening tools for identifying those likely to experience higher uptake of nicotine... - Colorectal cancer mortality: effectiveness of biennial screening for fecal occult bloodJ S Mandel
Division of Environmental and Occupational Health, School of Public Health, University of Minnesota, Minneapolis 55455, USA
J Natl Cancer Inst 91:434-7. 1999..Herein, we provide updated results-through 18 years of follow-up--from the Minnesota trial that address the apparent inconsistent findings among the trials regarding biennial screening... - Impact of training on work-related assaultNancy M Nachreiner
Center for Violence Prevention and Control, Division of Environmental Health Sciences, School of Public Health, University of Minnesota, 420 Delaware Street SE, Minneapolis, MN 55455, USA
Res Nurs Health 28:67-78. 2005..Additional research is necessary to obtain more specific details on occupational violence training, including training content and methods, to understand more thoroughly the impact of training on occupational violence... - Tractor-related injuries: a population-based study of a five-state region in the MidwestKathleen Ferguson Carlson
Regional Injury Prevention Research Center, Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455, USA
Am J Ind Med 47:254-64. 2005..Compared with ages 35-44, decreased risks were identified for those less than 5, 5-9, 10-14, 15-19, and 20-24. CONCLUSIONS: Risk of tractor injury among agricultural household members varied by gender, age, and prior injury experience. ... - Metabolites of a tobacco-specific lung carcinogen in the urine of elementary school-aged childrenS S Hecht
University of Minnesota Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA
Cancer Epidemiol Biomarkers Prev 10:1109-16. 2001..Our data indicate that objective biomarkers of carcinogen uptake are important in studies of childhood exposure to ETS and cancer later in life... - Proper interpretation of non-differential misclassification effects: expectations vs observationsAnne M Jurek
Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, MN 55455 0392, USA
Int J Epidemiol 34:680-7. 2005..Thus, as noted before, exposure misclassification can spuriously increase the observed strength of an association even when the misclassification process is non-differential and the bias it produced is towards the null... - An epidemiological study of the magnitude and consequences of work related violence: the Minnesota Nurses' StudyS G Gerberich
Regional Injury Prevention Research Center, and Occupational Injury Prevention Research Training Program, Division of Environmental and Occupational Health, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
Occup Environ Med 61:495-503. 2004..To identify the magnitude of and potential risk factors for violence within a major occupational population... 
Children's behavioral traits and risk of injury: analyses from a case-control study of agricultural householdsKathleen F Carlson
Polytrauma and Blast Related Injuries QUERI, Center for Chronic Disease Outcomes Research, VA Medical Center 152 2E, One Veterans Drive, Minneapolis, MN 55417, USA
J Safety Res 40:97-103. 2009..Children on family agricultural operations have high risk of injury. The association between children's behavioral traits and their risk of injury is not well understood...- Risk factors for work-related assaults on nursesSusan Goodwin Gerberich
Regional Injury Prevention Research Center and Center for Violence Prevention and Control, Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
Epidemiology 16:704-9. 2005..Work-related homicides have been the subject of considerable study, but little is known about nonfatal violence and relevant risk factors... - Asthma, atopy, and lung function among racially diverse, poor inner-urban Minneapolis schoolchildrenIan A Greaves
Division of Environmental Health Sciences, School of Public Health, University of Minnesota, MMC 807, 420 Delaware Street S E, Minneapolis, MN 55455, USA
Environ Res 103:257-66. 2007..A history of physician-diagnosed asthma was not associated with decreased lung function. Factors other than poverty, inner-urban living, and IgE levels (atopy) need to be considered in the development of childhood asthma... - Violence against educators: a population-based studySusan G Gerberich
Regional Injury Prevention Research Center and Center for Violence Prevention and Control, Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, MN55455, USA
J Occup Environ Med 53:294-302. 2011..Identify the magnitude and risk factors for occupational physical assault (PA) and nonphysical violence (NPV) against Minnesota educators... - Serum salicylate levels and risk of recurrent colorectal adenomasAasma Shaukat
Division of Gastroenterology, Department of Medicine and Minneapolis Veterans Affairs Medical Center, University of Minnesota, Minneapolis, MN 55417, USA
Cancer Epidemiol Biomarkers Prev 20:679-82. 2011..Some plants contain salicylates, and individuals not taking aspirin may have measurable salicylate levels. However, the association between serum salicylate level and recurrence of adenoma in nonusers of aspirin has not been studied... - Indoor air quality in two urban elementary schools--measurements of airborne fungi, carpet allergens, CO2, temperature, and relative humidityGurumurthy Ramachandran
Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455, USA
J Occup Environ Hyg 2:553-66. 2005..The results show that for fungi and cat allergens, the school environment can be an important exposure source for children... - Carbohydrate, glycemic index, and glycemic load and colorectal adenomas in the Prostate, Lung, Colorectal, and Ovarian Screening StudyAndrew Flood
University of Minnesota, Minneapolis, MN, Henry Ford Hospital, Detroit, MI, USA
Am J Clin Nutr 84:1184-92. 2006..It is possible that high-glycemic-load diets, through their hyperinsulinemic effects, can increase the risk of colorectal cancer... - Exposure-measurement error is frequently ignored when interpreting epidemiologic study resultsAnne M Jurek
Department of Pediatrics, University of Minnesota, Mayo Mail Code 715, 420 Delaware St SE, Minneapolis, MN 55455, USA
Eur J Epidemiol 21:871-6. 2006..One important source of error in study results is error in measuring exposures. When interpreting study results, one should consider the impact that exposure-measurement error (EME) might have had on study results... - Invited commentary: advancing propensity score methods in epidemiologyJ Michael Oakes
Division of Epidemiology and Community Health, Minnesota Population Center, University of Minnesota, Minneapolis, MN 55454, USA
Am J Epidemiol 165:1119-21; discussion 1122-3. 2007..The benefits of propensity score methods (and PSC) lie not only with potentially improved effect estimation but with conceptualization and practice as well... - School resources, resource allocation, and risk of physical assault against Minnesota educatorsStarr K Sage
Regional Injury Prevention Research Center and Center for Violence Prevention and Control, Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
Accid Anal Prev 42:1-9. 2010..Research to further explore the nature of the relations between disparities in school resources and spending, resource allocations, and PA will be important to the continued development of relevant prevention strategies... - Variation in detection of adenomas and polyps by colonoscopy and change over time with a performance improvement programAasma Shaukat
Department of Medicine, Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota, USA
Clin Gastroenterol Hepatol 7:1335-40. 2009..There has been no prospective, community-based study to track changes in adenoma detection by individual physicians over time and to determine the effectiveness of targeted educational interventions... - Difference in work-related violence by nurse license typeNancy M Nachreiner
Center for Violence Prevention and Control, Regional Injury Prevention Research Center, Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
J Prof Nurs 23:290-300. 2007..A better understanding of how this problem varies by license type and work setting will assist in designing efficacious interventions... - Work practices and childhood agricultural injuryMuree Larson-Bright
Regional Injury Prevention Research Center, Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Mayo Mail Code 807, 420 Delaware St SE, Minneapolis, MN 55455, USA
Inj Prev 13:409-15. 2007..To evaluate whether children's agricultural work practices were associated with agricultural injury and to identify injury and work practice predictors... - Uncertainty analysis: an example of its application to estimating a survey proportionAnne M Jurek
Department of Pediatrics, University of Minnesota, Mayo Mail Code 715, 420 Delaware St SE, Minneapolis, MN 55455, USA
J Epidemiol Community Health 61:650-4. 2007..A basic example is presented illustrating uncertainty analyses for four proportions estimated from a survey of the epidemiological literature... - Colorectal cancer screening adherence in a general populationMark W Yeazel
Department of Family Practice and Community Health, School of Medicine, University of Minnesota, MMC 381, 420 Delaware Street SE, Minneapolis, MN 55455, USA
Cancer Epidemiol Biomarkers Prev 13:654-7. 2004..This article describes the self-reported colorectal cancer (CRC) screening adherence rates of adults, aged 50 years and older, living in five nonurban Minnesota counties... - Outdoor, indoor, and personal exposure to VOCs in childrenJohn L Adgate
Division of Environmental Health Sciences, School of Public Health, University of Minnesota, 520 Delaware Street SE, Minneapolis, MN 55455, USA
Environ Health Perspect 112:1386-92. 2004..Median and upper-bound H and P exposures were well above health benchmarks for several compounds, so outdoor measurements likely underestimate long-term health risks from children's exposure to these compounds... - False-positive cancer screens and health-related quality of lifePatricia M McGovern
Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Mayo Del Code 807, 420 Delaware Street SE, Minneapolis, MN 55455, USA
Cancer Nurs 27:347-52. 2004..Implications for oncology nurses include the need to consider the emotional consequences of screening in association with screen reliability and validity... - Recruitment, retention, and compliance results from a probability study of children's environmental health in economically disadvantaged neighborhoodsKen Sexton
Division of Environmental and Occupational Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
Environ Health Perspect 111:731-6. 2003..There is an ongoing need, however, to improve understanding of the cultural, economic, psychologic, and social determinants of study participation among this population... - Ammonium perfluorooctanoate production and occupational mortalityJessica I Lundin
Division of Environmental Health Sciences, University of Minnesota, School of Public Health, Minneapolis, MN 55455, USA
Epidemiology 20:921-8. 2009..Perfluorooctanoate (PFOA) is a synthetic chemical widely detectable in blood of nonoccupationally exposed persons. Its human health effects are not well-characterized... - Aspirin may be more effective in preventing colorectal adenomas in patients with higher BMI (United States)Sangmi Kim
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC 27599-7555, USA
Cancer Causes Control 17:1299-304. 2006..The more pronounced effect of 325 mg aspirin in individuals with higher BMI suggests a possible protective role of anti-inflammatory aspirin against increased adipose-driven cytokines among obese subjects... - Relation between policies and work related assault: Minnesota Nurses' StudyN M Nachreiner
Center for Violence Prevention and Control, Regional Injury Prevention Research Center, Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, MN 55455, USA
Occup Environ Med 62:675-81. 2005..To assess the relation between violence prevention policies and work related assault... - Chest radiography as the comparison for spiral CT in the National Lung Screening TrialTimothy R Church
Division of Environmental and Occupational Health, School of Public Health, University of Minnesota, 420 Delaware St SE, MMC 197, Minneapolis, MN 55455, USA
Acad Radiol 10:713-5. 2003 - Parents' safety beliefs and childhood agricultural injuryMuree Larson-Bright
Regional Injury Prevention Research Center, Division of Environmental Health Sciences, School of Public Health, University of Minnesota, Minneapolis, Minnesota 55455, USA
Am J Ind Med 52:724-33. 2009..This study examined potential associations between parental safety beliefs and children's chore assignments or risk of agricultural injury... - Decline in perfluorooctanesulfonate and other polyfluoroalkyl chemicals in American Red Cross adult blood donors, 2000-2006Geary W Olsen
3M Company, Medical Department, St Paul, Minnesota, American Red Cross, North Central Region, St Paul, Minnesota, USA
Environ Sci Technol 42:4989-95. 2008..Direct and indirect exposure sources of PFOA could include historic and ongoing electrochemical cell fluorination (ECF) of PFOA, telomer production of PFOA, fluorotelomer-based precursors, and other fluoropoly-mer production... - Risk stratification in diabetic patients with a previous myocardial infarctionJames J Bailey
Center for Information Technology, National Institutes of Health, Bethesda, MD, USA
J Electrocardiol 36:121-5. 2003..When the unstratified cases were subsequently tested with EPS, the difference between the two groups was even more marked... - A randomized trial of aspirin to prevent colorectal adenomasJohn A Baron
Norris Cotton Cancer Center, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
N Engl J Med 348:891-9. 2003..Laboratory and epidemiologic data suggest that aspirin has an antineoplastic effect in the large bowel... - Factors associated with human small aggressive non small cell lung cancerC Martin Tammemagi
Department of Community Health Sciences, Brock University, 500 Glenridge Avenue, St Catharines, Ontario, Canada L2S 3A1
Cancer Epidemiol Biomarkers Prev 16:2082-9. 2007..Such small aggressive NSCLCs (SA-NSCLC) are no longer resectable with curative intent, carry a grave prognosis, and may involve unique biological pathways. This is a study of factors associated with SA-NSCLC... - Separation of health and statisticsTimothy R Church
J Natl Cancer Inst 100:452-3. 2008 - Validity of four self-reported colorectal cancer screening modalities in a general population: differences over time and by intervention assignmentResa M Jones
Department of Epidemiology and Community Health, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298, USA
Cancer Epidemiol Biomarkers Prev 17:777-84. 2008..Those exposed to more intense interventions to modify screening behavior seemed more likely to overestimate their screening rates compared with those who were not exposed... - Serum concentrations of perfluorooctanesulfonate and other fluorochemicals in an elderly population from Seattle, WashingtonGeary W Olsen
Medical Department, 3M Company, Mail Stop 220 3W 05, St Paul, MN 55144, USA
Chemosphere 54:1599-611. 2004..Similar to other reported findings of younger adults, the geometric mean serum PFOS concentration in non-occupational adult populations likely approximates 30-40 ppb with 95% of the population's serum PFOS concentrations below 100 ppb... - Vitamin D, calcium supplementation, and colorectal adenomas: results of a randomized trialMaria V Grau
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH, USA
J Natl Cancer Inst 95:1765-71. 2003..Although these nutrients are inter-related metabolically in bone and in the normal intestine, their potential interactions in large-bowel carcinogenesis are not well understood... - Neoplastic and antineoplastic effects of beta-carotene on colorectal adenoma recurrence: results of a randomized trialJohn A Baron
Department of Medicine, Dartmouth Medical School, Evergreen Center, Lebanon, NH 03766, USA
J Natl Cancer Inst 95:717-22. 2003..Although beta-carotene supplementation appeared not to increase the risk of cancer generally, it is not clear if smoking and/or alcohol use alters the effect of beta-carotene on carcinogenesis at sites outside the lung... - Prostate Cancer Screening in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial: findings from the initial screening round of a randomized trialGerald L Andriole
Division of Urologic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
J Natl Cancer Inst 97:433-8. 2005..We describe the population enrolled in the PLCO trial, their baseline PSA and DRE screening results, and diagnostic follow-up results during the first year of follow-up... - Folic acid for the prevention of colorectal adenomas: a randomized clinical trialBernard F Cole
Department of Community and Family Medicine, Dartmouth Medical School, Hanover, NH, USA
JAMA 297:2351-9. 2007..Laboratory and epidemiological data suggest that folic acid may have an antineoplastic effect in the large intestine... - Colorectal cancer in patients under close colonoscopic surveillanceDouglas J Robertson
Section of Gastroenterology, VA Medical Center, White River Junction, Vermont 05009, USA
Gastroenterology 129:34-41. 2005..We determined the incidence of CRC in patients under colonoscopic surveillance and examined the circumstances and risk factors for CRC and adenoma with high-grade dysplasia... - Children's exposure to volatile organic compounds as determined by longitudinal measurements in bloodKen Sexton
University of Texas School of Public Health, Brownsville Regional Campus, Brownsville, Texas, USA
Environ Health Perspect 113:342-9. 2005..For siblings living in the same household, we found strong statistical associations between measured blood VOC concentrations... - Offering patients colorectal cancer screeningTimothy R Church
J Natl Cancer Inst 97:328-9. 2005 - Association of genetic variants in the calcium-sensing receptor with risk of colorectal adenomaUlrike Peters
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Rockville, MD, USA
Cancer Epidemiol Biomarkers Prev 13:2181-6. 2004..We assessed the associations between CASR gene variants and risk for colorectal adenoma, a cancer precursor. We further investigated gene-diet interactions between the CASR variants and calcium intake on adenoma risk... - High serum selenium and reduced risk of advanced colorectal adenoma in a colorectal cancer early detection programUlrike Peters
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, Maryland, USA
Cancer Epidemiol Biomarkers Prev 15:315-20. 2006..Although substantial evidence suggests that smoking is a strong effect modifier for other antioxidative nutrients, little is known about smoking-selenium interactions in colorectal tumors... - Screening for colorectal cancer by colonoscopy: adding to the evidenceTimothy R Church
JAMA 295:2411-2. 2006 - Cigarette smoking, N-acetyltransferase genes and the risk of advanced colorectal adenomaRoxana Moslehi
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, 6120 Executive Blvd, EPS 8047, Rockville, MD 20852 USA
Pharmacogenomics 7:819-29. 2006..Our interest is in the polymorphisms within the NAT1 and NAT2 genes that influence the tobacco-colorectal tumor relationship by impacting on the metabolic activation and detoxification of tobacco smoke-derived carcinogens... - Prostate-specific antigen and prostate cancer prognosisTimothy R Church
J Natl Cancer Inst 98:1509-10. 2006 - Calcium intake and colorectal adenoma in a US colorectal cancer early detection programUlrike Peters
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, USA
Am J Clin Nutr 80:1358-65. 2004..Calcium can reduce the risk of colorectal tumors by binding secondary bile and fatty acids, which leads to antiproliferative effects in the bowel, or by acting directly on the colonic epithelium, which affects differentiation and apoptosis... - Prolonged effect of calcium supplementation on risk of colorectal adenomas in a randomized trialMaria V Grau
Department of Community and Family Medicine, Dartmouth Medical School, Lebanon, NH, USA
J Natl Cancer Inst 99:129-36. 2007..Calcium supplementation has been shown to decrease the risk of recurrence of colorectal adenomas in randomized trials. However, the duration of this protective effect after cessation of active supplementation is not known... - Decision to implant a cardioverter defibrillator after myocardial infarction: the role of ejection fraction v. other risk factor markersJames J Bailey
Center for Information Technology, National Institutes of Health, Bethesda, Maryland 20892 5620, USA
Med Decis Making 27:151-60. 2007..Whether further refinement in risk estimation could be achieved with additional clinical testing to qualify patients for primary prevention with ICDs remains problematic... - Re: All-cause mortality in randomized trials of cancer screeningTimothy R Church
J Natl Cancer Inst 94:861; author reply 865-6. 2002 - Simulated screening for prostate cancer: the useful modelTimothy R Church
J Natl Cancer Inst 95:838-9. 2003 - Genetic variation in base excision repair genes and the prevalence of advanced colorectal adenomaSonja I Berndt
Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Cancer Res 67:1395-404. 2007..51; 95% CI, 0.33-0.78, P = 0.002 for PARP1 A284A). This study suggests that polymorphisms in APEX1, XRCC1, and PARP1 may be associated with advanced colorectal adenoma... - Lung cancer: interobserver agreement on interpretation of pulmonary findings at low-dose CT screeningDavid S Gierada
Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Blvd, St Louis, MO 63105, USA
Radiology 246:265-72. 2008..To evaluate agreement among radiologists on the interpretation of pulmonary findings at low-dose computed tomographic (CT) screening examinations for lung cancer...