Cheng Ming Chuong

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. pmc Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1
    Ji Li
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    J Invest Dermatol 132:2681-90. 2012
  2. pmc Module-based complexity formation: periodic patterning in feathers and hairs
    Cheng Ming Chuong
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Wiley Interdiscip Rev Dev Biol 2:97-112. 2013
  3. pmc Physiological regeneration of skin appendages and implications for regenerative medicine
    Cheng Ming Chuong
    Department of Pathology, University of Southern California, School of Medicine, Los Angeles, California, USA
    Physiology (Bethesda) 27:61-72. 2012
  4. doi request reprint The river of stem cells
    Cheng Ming Chuong
    Department of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, Los Angeles, CA 90033, USA
    Cell Stem Cell 4:100-2. 2009
  5. ncbi request reprint The biology of feather follicles
    Mingke Yu
    Department of Pathology, Department of Cell and Neurobiology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Int J Dev Biol 48:181-91. 2004
  6. ncbi request reprint The morphogenesis of feathers
    Mingke Yu
    Department of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, Los Angeles, California 90033, USA
    Nature 420:308-12. 2002
  7. pmc Wnt3a gradient converts radial to bilateral feather symmetry via topological arrangement of epithelia
    Zhicao Yue
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Proc Natl Acad Sci U S A 103:951-5. 2006
  8. pmc Conversion of the nipple to hair-bearing epithelia by lowering bone morphogenetic protein pathway activity at the dermal-epidermal interface
    Julie Ann Mayer
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Am J Pathol 173:1339-48. 2008
  9. ncbi request reprint Morphogenesis of chicken liver: identification of localized growth zones and the role of beta-catenin/Wnt in size regulation
    Sanong Suksaweang
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Dev Biol 266:109-22. 2004
  10. ncbi request reprint Distinct Wnt members regulate the hierarchical morphogenesis of skin regions (spinal tract) and individual feathers
    Chung Hsing Chang
    Department of Pathology, Keck School of Medicine, University of Southern California, HMR 305D, 2011 Zonal Avenue, Los Angeles, CA 90033, USA
    Mech Dev 121:157-71. 2004

Research Grants

  1. Size regulation of skin appendages
    Cheng Ming Chuong; Fiscal Year: 2004
  2. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2005
  3. Size regulation of skin appendages
    Cheng Ming Chuong; Fiscal Year: 2005
  4. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2006
  5. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2006
  6. Size regulation of skin appendages
    Cheng Ming Chuong; Fiscal Year: 2006
  7. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2007
  8. Size Regulation of Ectodermal Organs
    Cheng Ming Chuong; Fiscal Year: 2007
  9. Size Regulation of Ectodermal Organs
    Cheng Ming Chuong; Fiscal Year: 2009
  10. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2009

Collaborators

Detail Information

Publications58

  1. pmc Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1
    Ji Li
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    J Invest Dermatol 132:2681-90. 2012
    ..These results highlight the importance of DNA methylation in maintaining stem cell homeostasis during the development and regeneration of ectodermal organs...
  2. pmc Module-based complexity formation: periodic patterning in feathers and hairs
    Cheng Ming Chuong
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Wiley Interdiscip Rev Dev Biol 2:97-112. 2013
    ..New hair follicles can be generated after wounding. Hairs and feathers can be reconstituted through self-organization of dissociated progenitor cells...
  3. pmc Physiological regeneration of skin appendages and implications for regenerative medicine
    Cheng Ming Chuong
    Department of Pathology, University of Southern California, School of Medicine, Los Angeles, California, USA
    Physiology (Bethesda) 27:61-72. 2012
    ....
  4. doi request reprint The river of stem cells
    Cheng Ming Chuong
    Department of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, Los Angeles, CA 90033, USA
    Cell Stem Cell 4:100-2. 2009
    ..The work implies stem cell states can be regulated to form different numbers of intermediate stops, depending on physiological requirements...
  5. ncbi request reprint The biology of feather follicles
    Mingke Yu
    Department of Pathology, Department of Cell and Neurobiology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Int J Dev Biol 48:181-91. 2004
    ..Thus, the developmental biology of feather follicles provides a multi-dimension research paradigm that links molecular activities and cellular behaviors to functional morphology at the organismal level...
  6. ncbi request reprint The morphogenesis of feathers
    Mingke Yu
    Department of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, Los Angeles, California 90033, USA
    Nature 420:308-12. 2002
    ....
  7. pmc Wnt3a gradient converts radial to bilateral feather symmetry via topological arrangement of epithelia
    Zhicao Yue
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Proc Natl Acad Sci U S A 103:951-5. 2006
    ....
  8. pmc Conversion of the nipple to hair-bearing epithelia by lowering bone morphogenetic protein pathway activity at the dermal-epidermal interface
    Julie Ann Mayer
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Am J Pathol 173:1339-48. 2008
    ..We propose that during evolution of the nipple, the BMP pathway was co-opted to suppress hair follicle formation and create a more functional milk delivery apparatus...
  9. ncbi request reprint Morphogenesis of chicken liver: identification of localized growth zones and the role of beta-catenin/Wnt in size regulation
    Sanong Suksaweang
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Dev Biol 266:109-22. 2004
    ....
  10. ncbi request reprint Distinct Wnt members regulate the hierarchical morphogenesis of skin regions (spinal tract) and individual feathers
    Chung Hsing Chang
    Department of Pathology, Keck School of Medicine, University of Southern California, HMR 305D, 2011 Zonal Avenue, Los Angeles, CA 90033, USA
    Mech Dev 121:157-71. 2004
    ..Wnt 5a and 11 triggered the JNK pathway. Thus distinctive Wnts have positive and negative roles in forming the dermis, tracts, interbud spacing and the growth and shaping of individual buds...
  11. pmc In search of the Golden Fleece: unraveling principles of morphogenesis by studying the integrative biology of skin appendages
    Michael W Hughes
    Department of Pathology, School of Medicine, University of Southern California, HMR 315B, 2011 Zonal Ave, Los Angeles, CA 90033, USA
    Integr Biol (Camb) 3:388-407. 2011
    ..Future work will follow these leads to develop a systems biology view and understanding in the morphogenetic principles that govern the development and regeneration of ectodermal organs...
  12. ncbi request reprint Morphoregulation of avian beaks: comparative mapping of growth zone activities and morphological evolution
    Ping Wu
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Dev Dyn 235:1400-12. 2006
    ..Implications of topobiology vs. molecular blueprint concepts in the Evo-Devo of avian beak forms are discussed...
  13. pmc Morpho-regulation of ectodermal organs: integument pathology and phenotypic variations in K14-Noggin engineered mice through modulation of bone morphogenic protein pathway
    Maksim Plikus
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Am J Pathol 164:1099-114. 2004
    ..Therefore during organogenesis, BMP antagonists can produce a spectrum of phenotypes in a stage-dependent manner by adjusting the level of BMP activity. The distinction between phenotypic variations and pathological changes is discussed...
  14. ncbi request reprint Shift of localized growth zones contributes to skin appendage morphogenesis: role of the Wnt/beta-catenin pathway
    Rajas Chodankar
    Department of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, Los Angeles, CA 90033, USA
    J Invest Dermatol 120:20-6. 2003
    ..These data suggest that skin appendages are built to specific shapes by adding new cells from well-positioned and controlled localized growth zones and that Wnt activity is involved in regulating such localized growth zone activity...
  15. ncbi request reprint Sculpting skin appendages out of epidermal layers via temporally and spatially regulated apoptotic events
    Chung Hsing Chang
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Invest Dermatol 122:1348-55. 2004
    ..The current work complements our recent work on LoGZ to show how adding and removing cell masses in temporally and spatially specific ways are coordinated to sculpt skin appendages from epidermal layers...
  16. ncbi request reprint Integument pattern formation involves genetic and epigenetic controls: feather arrays simulated by digital hormone models
    Ting Xin Jiang
    Department of Pathology, University of Southern California, Los Angeles, California 90033, USA
    Int J Dev Biol 48:117-35. 2004
    ..The Digital Hormone Model can also be applied to swarming robot navigation, reaching intelligent automata and representing a self-re-configurable type of control rather than a follow-the-instruction type of control...
  17. ncbi request reprint Molecular signaling in feather morphogenesis
    Chih Min Lin
    Department of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, Los Angeles, CA 90033, USA
    Curr Opin Cell Biol 18:730-41. 2006
    ..Progress has been made in elucidating feather morphogenesis in five successive phases: macro-patterning, micro-patterning, intra-bud morphogenesis, follicle morphogenesis and regenerative cycling...
  18. ncbi request reprint Evo-Devo of amniote integuments and appendages
    Ping Wu
    Department of Pathology, University of Southern California, Los Angeles, CA, USA
    Int J Dev Biol 48:249-70. 2004
    ..A hypothetical Evo-Devo space where diverse integument appendages can be placed according to complex phenotypes and novel developmental mechanisms is presented...
  19. pmc Self-organizing and stochastic behaviors during the regeneration of hair stem cells
    Maksim V Plikus
    Department of Pathology, University of Southern California USC, Los Angeles, CA 90033, USA
    Science 332:586-9. 2011
    ..This regenerative strategy is robust and versatile because relative activator/inhibitor strengths can be modulated easily, adapting the organism to different physiological and evolutionary needs...
  20. pmc From buds to follicles: matrix metalloproteinases in developmental tissue remodeling during feather morphogenesis
    Ting Xin Jiang
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Differentiation 81:307-14. 2011
    ..This work demonstrates that MMPs and their inhibitors are not only important in injury repair, but also in development tissue remodeling as demonstrated here for the formation of feather follicles...
  21. pmc Reptile scale paradigm: Evo-Devo, pattern formation and regeneration
    Cheng Chang
    Department of Pathology, University of Southern California, Los Angeles, 90033, USA
    Int J Dev Biol 53:813-26. 2009
    ..Here, we underscore how further development of this novel experimental model will be valuable in filling the gaps of our understanding of the Evo-Devo of amniote integuments...
  22. pmc Spots and stripes: pleomorphic patterning of stem cells via p-ERK-dependent cell chemotaxis shown by feather morphogenesis and mathematical simulation
    Chih Min Lin
    Department of Pathology, University of Southern California, Los Angeles, CA 90033, USA
    Dev Biol 334:369-82. 2009
    ..This generic cell behavior model can be applied to model stem cell patterning behavior at large...
  23. ncbi request reprint Mapping stem cell activities in the feather follicle
    Zhicao Yue
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Nature 438:1026-9. 2005
    ..The changing topology of stem cell activities may contribute to the construction of complex feather forms...
  24. ncbi request reprint Engineering stem cells into organs: topobiological transformations demonstrated by beak, feather, and other ectodermal organ morphogenesis
    Cheng Ming Chuong
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Curr Top Dev Biol 72:237-74. 2006
    ..Promises and problems in reconstitute feather/hair follicles and other organs are discussed. Finally, simple modification at the topobiological level may lead to novel morphology for natural selection at the evolution level...
  25. ncbi request reprint Adaptation to the sky: Defining the feather with integument fossils from mesozoic China and experimental evidence from molecular laboratories
    Cheng Ming Chuong
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Exp Zool B Mol Dev Evol 298:42-56. 2003
    ..A model of feather evolution from feather bud --> barbs --> barbules --> rachis is presented, which is opposite to the old view of scale plate --> rachis --> barbs --> barbules (Regal, '75; Q Rev Biol 50:35)...
  26. pmc Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration
    Maksim V Plikus
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Nature 451:340-4. 2008
    ....
  27. pmc Shaping organs by a wingless-int/Notch/nonmuscle myosin module which orients feather bud elongation
    Ang Li
    Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
    Proc Natl Acad Sci U S A 110:E1452-61. 2013
    ....
  28. pmc Roles of EphB3/ephrin-B1 in feather morphogenesis
    Sanong Suksaweang
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Int J Dev Biol 56:719-28. 2012
    ..Consequently, we propose that interaction between ephrin-B1 and its receptor is involved in boundary stabilization during feather morphogenesis...
  29. pmc Sprouty/FGF signaling regulates the proximal-distal feather morphology and the size of dermal papillae
    Zhicao Yue
    Department of Pathology, University of Southern California, Los Angeles, CA 90033, United States
    Dev Biol 372:45-54. 2012
    ..These results suggest that coordinated Sprouty/FGF pathway activity at different stages is important to modulate feather epidermal stem cells to form distinct feather morphologies along the proximal-distal feather axis...
  30. pmc Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity
    Maksim V Plikus
    Department of Pathology, University of Southern California, Los Angeles, 90033, USA
    Int J Dev Biol 53:857-68. 2009
    ..Such a novel understanding has important implications in the field of regenerative medicine. The unexpected links with Bmp2 expression in subcutaneous adipocytes has implications for systems biology and Evo-Devo...
  31. pmc Pattern formation today
    Cheng Ming Chuong
    Department of Pathology, University of Southern California, Los Angeles, USA
    Int J Dev Biol 53:653-8. 2009
    ..J. Dev. Biol. represents a sample of our knowledge of pattern formation today, which will help to stimulate more research on this fundamental process...
  32. ncbi request reprint Morphoregulation of teeth: modulating the number, size, shape and differentiation by tuning Bmp activity
    Maksim V Plikus
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Evol Dev 7:440-57. 2005
    ..The involvement of related pathways and the implication of morphoregulation in tooth evolution are discussed...
  33. ncbi request reprint Molecular biology of feather morphogenesis: a testable model for evo-devo research
    Randall B Widelitz
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Exp Zool B Mol Dev Evol 298:109-22. 2003
    ..In this paper, principles guiding feather tract formation, distributions of individual feathers within the tracts and variations in feather forms are discussed at a cellular and molecular level...
  34. pmc Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling
    Maksim V Plikus
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Proc Natl Acad Sci U S A 110:E2106-15. 2013
    ..Our results uncover diurnal mitotic gating as the essential protective mechanism in highly proliferative hair follicles and offer strategies for minimizing or maximizing cytotoxicity of radiation therapies...
  35. pmc Specialized stem cell niche enables repetitive renewal of alligator teeth
    Ping Wu
    Department of Pathology, University of Southern California, Los Angeles, CA 90033, USA
    Proc Natl Acad Sci U S A 110:E2009-18. 2013
    ..Understanding how these signaling molecules interact in tooth development in this model may help us to learn how to stimulate growth of adult teeth in mammals...
  36. pmc A simplified procedure to reconstitute hair-producing skin
    Lily F Lee
    Division of Plastic Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Tissue Eng Part C Methods 17:391-400. 2011
    ..This procedure enables flexible size and shape of the reconstituted skin, so clinical applications can be envisioned for the future when large numbers of multipotential skin stem cells become available...
  37. ncbi request reprint Rooster feathering, androgenic alopecia, and hormone-dependent tumor growth: what is in common?
    Julie Ann Mayer
    Department of Pathology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, Los Angeles, CA 90033, USA
    Differentiation 72:474-88. 2004
    ..It is now possible to test these hypotheses using the chicken model to learn fundamental mechanisms on how sex hormones affect organogenesis, epithelial organ cycling, and growth-related tumorigenesis...
  38. ncbi request reprint Mammary glands and feathers: comparing two skin appendages which help define novel classes during vertebrate evolution
    Randall B Widelitz
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Semin Cell Dev Biol 18:255-66. 2007
    ..Besides natural selection, both are regulated by sex hormones and acquired a secondary function for attracting mates, contributing to sexual selection...
  39. ncbi request reprint Molecular shaping of the beak
    Ping Wu
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Science 305:1465-6. 2004
    ..These growth zones are associated with bone morphogenetic protein 4 (BMP4) activity. By "tinkering" with BMP4 in beak prominences, the shapes of the chicken beak can be modulated...
  40. pmc Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation
    Eve Kandyba
    Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research, University of Southern California, Los Angeles, CA 90033, USA
    Proc Natl Acad Sci U S A 110:1351-6. 2013
    ....
  41. pmc Accelerated closure of skin wounds in mice deficient in the homeobox gene Msx2
    Jennifer Yeh
    Department of Pathology, University of Southern California, Los Angeles, CA, USA
    Wound Repair Regen 17:639-48. 2009
    ..Thus, our results suggest that Msx2 regulates the cellular competence of keratinocytes and fibroblasts in skin injury repair...
  42. pmc Regenerative patterning in Swarm Robots: mutual benefits of research in robotics and stem cell biology
    Michael Rubenstein
    Information Sciences Institute and Computer Science Department, University of Southern California, 90292, USA
    Int J Dev Biol 53:869-81. 2009
    ....
  43. ncbi request reprint A mouthful of epithelial-mesenchymal interactions
    Michael W Hughes
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    J Invest Dermatol 121:vii-viii. 2003
  44. ncbi request reprint Regenerative hair waves in aging mice and extra-follicular modulators follistatin, dkk1, and sfrp4
    Chih Chiang Chen
    1 Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA 2 Institute of Clinical Medicine and Department of Dermatology, National Yang Ming University, Taipei, Taiwan 3 Department of Dermatology, Taipei Veterans General Hospital, Taipei, Taiwan
    J Invest Dermatol 134:2086-96. 2014
    ..We present an excitable medium model to simulate the cycling behavior in aging mice and illustrate how the interorgan macroenvironment can regulate the aging process by integrating both "activator" and "inhibitor" signals. ..
  45. ncbi request reprint Development and evolution of the amniote integument: current landscape and future horizon
    Cheng Ming Chuong
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Exp Zool B Mol Dev Evol 298:1-11. 2003
    ....
  46. doi request reprint Many paths to alopecia via compromised regeneration of hair follicle stem cells
    Ji Li
    Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China
    J Invest Dermatol 133:1450-2. 2013
    ..These studies will provide new clues and targets for designing therapeutic strategies for hair loss...
  47. pmc Tuning Wnt signals for more or fewer hairs
    Ming Xing Lei
    Department of Pathology, University of Southern California, Los Angeles, CA, USA
    J Invest Dermatol 133:7-9. 2013
    ..This new understanding presents multiple possibilities to fine tune Wnt signaling for desired hair growth...
  48. pmc Complex hair cycle domain patterns and regenerative hair waves in living rodents
    Maksim V Plikus
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    J Invest Dermatol 128:1071-80. 2008
    ..Regenerative hair waves are different from the developmental wave of newly forming hair follicles. The study provides insights into the dynamic states of adult skin and physiological regulation of organ regeneration...
  49. ncbi request reprint Preface to pattern formation special issue
    Cheng Ming Chuong
    Department of Pathology, Univ Southern California, Los Angeles, USA
    Int J Dev Biol 53:651. 2009
    ....
  50. ncbi request reprint Defining hair follicles in the age of stem cell bioengineering
    Cheng Ming Chuong
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    J Invest Dermatol 127:2098-100. 2007
    ..Some result in hair follicles; others are hair follicle-like. The challenge calls for the development of a set of criteria to define a hair follicle so that bioengineered products in the future can be evaluated...
  51. ncbi request reprint Homeobox genes, fetal wound healing, and skin regional specificity
    Cheng Ming Chuong
    University of Southern California, Los Angeles, CA, USA
    J Invest Dermatol 120:9-11. 2003
  52. pmc Building complex tissues: high-throughput screening for molecules required in hair engineering
    Lily F Lee
    Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    J Invest Dermatol 129:815-7. 2009
    ..In this issue, Havlickova et al. (2009) report a significant contribution to hair engineering with their human folliculoid microsphere assay...
  53. pmc PubFocus: semantic MEDLINE/PubMed citations analytics through integration of controlled biomedical dictionaries and ranking algorithm
    Maksim V Plikus
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    BMC Bioinformatics 7:424. 2006
    ..Search outputs generated by MEDLINE/PubMed are not well classified and require lengthy manual citation analysis. Automation of citation analytics can be very useful and timesaving for both novices and experts...
  54. ncbi request reprint Making waves with hairs
    Maksim Plikus
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    J Invest Dermatol 122:vii-ix. 2004
  55. ncbi request reprint Distinct mechanisms underlie pattern formation in the skin and skin appendages
    Randall B Widelitz
    Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Birth Defects Res C Embryo Today 78:280-91. 2006
    ..Much remains to be learned about complex pattern formation, if we are to bridge the gap between molecular biology and organism phenotypes...
  56. ncbi request reprint Synergistic coactivator function by coactivator-associated arginine methyltransferase (CARM) 1 and beta-catenin with two different classes of DNA-binding transcriptional activators
    Stephen S Koh
    Department of Pathology, University of Southern California, Los Angeles, California 90089, USA
    J Biol Chem 277:26031-5. 2002
    ..The synergistic coactivator function of beta-catenin and CARM1 is not restricted to steroid receptors because these two coactivators can also act synergistically with another type of DNA binding transcriptional activator, LEF-1/TCF-4...
  57. doi request reprint PI3K, Erk signaling in BMP7-induced epithelial-mesenchymal transition (EMT) of PC-3 prostate cancer cells in 2- and 3-dimensional cultures
    Minyoung Lim
    Program in Genetic, Molecular, and Cellular Biology, Keck School of Medicine, University of Southern California, Los Angeles, USA
    Horm Cancer 2:298-309. 2011
    ....
  58. doi request reprint Toward the isolation and culture of melanocyte stem cells
    Sung Jan Lin
    1 Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA 2 Institute of Biomedical Engineering, College of Medicine and College of Engineering, National Taiwan University, Taipei, Taiwan 3 Department of Dermatology, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan 4 Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei, Taiwan
    J Invest Dermatol 131:2341-3. 2011
    ..In this issue, Nishikawa-Torikai et al. report progress toward this end. MCSCs isolated from mouse hair follicles can be expanded in vitro in a feeder-layer culture system. Application to human systems can be expected...

Research Grants38

  1. Size regulation of skin appendages
    Cheng Ming Chuong; Fiscal Year: 2004
    ..This work will lead to a new understanding of the molecular basis of the size regulation of skin appendages. ..
  2. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2005
    ..Learning about the regulation of keratinocytes at different levels may help us guide appendage stem cells to form the tissues and organs needed in tissue engineering. ..
  3. Size regulation of skin appendages
    Cheng Ming Chuong; Fiscal Year: 2005
    ..This work will lead to a new understanding of the molecular basis of the size regulation of skin appendages. ..
  4. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2006
    ..Learning about the regulation of keratinocytes at different levels may help us guide appendage stem cells to form the tissues and organs needed in tissue engineering. ..
  5. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2006
    ..We hope you can expedite the approval of this relatively small supplement so we can evaluate these exciting possibilities promptly. Based on that, we may then develop a full scale study. ..
  6. Size regulation of skin appendages
    Cheng Ming Chuong; Fiscal Year: 2006
    ..This work will lead to a new understanding of the molecular basis of the size regulation of skin appendages. ..
  7. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2007
    ..Learning about the regulation of keratinocytes at different levels may help us guide appendage stem cells to form the tissues and organs needed in tissue engineering. ..
  8. Size Regulation of Ectodermal Organs
    Cheng Ming Chuong; Fiscal Year: 2007
    ..The knowledge acquired can be directed to make short hairs grow longer, and to engineer ectodermal stem cells into follicles with sustaining growth ability. ..
  9. Size Regulation of Ectodermal Organs
    Cheng Ming Chuong; Fiscal Year: 2009
    ..The knowledge acquired can be directed to make short hairs grow longer, and to engineer ectodermal stem cells into follicles with sustaining growth ability. ..
  10. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2009
    ..The work has practical significance in how to properly set environments for stem cells to make a new organ, as well as for those who use the mouse skin as a model for carcinogenesis study, drug delivery or stem cell research. ..
  11. Size Regulation of Ectodermal Organs
    Cheng Ming Chuong; Fiscal Year: 2010
    ..The knowledge acquired can be directed to make short hairs grow longer, and to engineer ectodermal stem cells into follicles with sustaining growth ability. ..
  12. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2010
    ..The work has practical significance in how to properly set environments for stem cells to make a new organ, as well as for those who use the mouse skin as a model for carcinogenesis study, drug delivery or stem cell research. ..
  13. Size Regulation of Ectodermal Organs
    Cheng Ming Chuong; Fiscal Year: 2009
    ..The knowledge acquired can be directed to make short hairs grow longer, and to engineer ectodermal stem cells into follicles with sustaining growth ability. ..
  14. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2010
    ..Here we propose to develop a novel planar hair forming protocol which integrates progress from our parent grant and others'hair research and may bring new hope to those who suffer from severe wounds and alopecia. ..
  15. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2004
    ..Learning about the regulation of keratinocytes at different levels may help us guide appendage stem cells to form the tissues and organs needed in tissue engineering. ..
  16. Size regulation of skin appendages
    Cheng Ming Chuong; Fiscal Year: 2003
    ..This work will lead to a new understanding of the molecular basis of the size regulation of skin appendages. ..
  17. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 1999
    ....
  18. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2000
    ....
  19. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2001
    ....
  20. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2000
    ....
  21. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2001
    ....
  22. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2002
    ....
  23. Size regulation of skin appendages
    Cheng Ming Chuong; Fiscal Year: 2002
    ..This work will lead to a new understanding of the molecular basis of the size regulation of skin appendages. ..
  24. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2002
    ....
  25. DEVELOPMENT AND REGENERATION OF SKIN APPENDAGES
    Cheng Ming Chuong; Fiscal Year: 2003
    ....
  26. Tissue Engineering of New Hair Formation
    Cheng Ming Chuong; Fiscal Year: 2010
    ..Here we propose to develop a novel planar hair forming protocol which integrates progress from our parent grant and others hair research and may bring new hope to those who suffer from severe wounds, and alopecia. ..