Baocheng Chu

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc A visible, targeted high-efficiency gene delivery and transfection strategy
    Qiao Ying Yuan
    Department of Geriatrics, Southwest Hospital, The Third Military Medical University, Chongqing 400038, China
    BMC Biotechnol 11:56. 2011
  2. ncbi request reprint Images in cardiovascular medicine. Serial high-spatial-resolution, multisequence magnetic resonance imaging studies identify fibrous cap rupture and penetrating ulcer into carotid atherosclerotic plaque
    Baocheng Chu
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    Circulation 113:e660-1. 2006
  3. ncbi request reprint Determination of carotid artery atherosclerotic lesion type and distribution in hypercholesterolemic patients with moderate carotid stenosis using noninvasive magnetic resonance imaging
    Baocheng Chu
    Department of Radiology, Box 357115, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA
    Stroke 35:2444-8. 2004
  4. ncbi request reprint Feasibility of in vivo, multicontrast-weighted MR imaging of carotid atherosclerosis for multicenter studies
    Baocheng Chu
    Department of Radiology, University of Washington, Seattle, Washington 98195, USA
    J Magn Reson Imaging 21:809-17. 2005
  5. ncbi request reprint Images in cardiovascular medicine. Detection of carotid atherosclerotic plaque ulceration, calcification, and thrombosis by multicontrast weighted magnetic resonance imaging
    Baocheng Chu
    Department of Radiology, University of Washington, 1959 NE Pacific St, Seattle, WA 98195, USA
    Circulation 112:e3-4. 2005
  6. ncbi request reprint Reproducibility of carotid atherosclerotic lesion type characterization using high resolution multicontrast weighted cardiovascular magnetic resonance
    Baocheng Chu
    Department of Radiology, University of Washington Medical Center, Seattle, Washington 98195, USA
    J Cardiovasc Magn Reson 8:793-9. 2006
  7. pmc Quantitative evaluation of high intensity signal on MIP images of carotid atherosclerotic plaques from routine TOF-MRA reveals elevated volumes of intraplaque hemorrhage and lipid rich necrotic core
    Kiyofumi Yamada
    Department of Radiology, University of Washington, Seattle, WA 98109 4325, USA
    J Cardiovasc Magn Reson 14:81. 2012
  8. pmc Magnetic [corrected] resonance imaging [corrected] features of the disruption-prone and the disrupted carotid plaque
    Baocheng Chu
    Vascular Imaging Laboratory, University of Washington, Seattle, Washington 98109, USA
    JACC Cardiovasc Imaging 2:883-96. 2009
  9. ncbi request reprint Intra- and interreader reproducibility of magnetic resonance imaging for quantifying the lipid-rich necrotic core is improved with gadolinium contrast enhancement
    Norihide Takaya
    Department of Radiology, University of Washington, Seattle, Washington, USA
    J Magn Reson Imaging 24:203-10. 2006
  10. doi request reprint Effect of rosuvastatin therapy on carotid plaque morphology and composition in moderately hypercholesterolemic patients: a high-resolution magnetic resonance imaging trial
    Hunter R Underhill
    Department of Radiology, University of Washington, Seattle, WA 98109, USA
    Am Heart J 155:584.e1-8. 2008

Detail Information

Publications44

  1. pmc A visible, targeted high-efficiency gene delivery and transfection strategy
    Qiao Ying Yuan
    Department of Geriatrics, Southwest Hospital, The Third Military Medical University, Chongqing 400038, China
    BMC Biotechnol 11:56. 2011
    ....
  2. ncbi request reprint Images in cardiovascular medicine. Serial high-spatial-resolution, multisequence magnetic resonance imaging studies identify fibrous cap rupture and penetrating ulcer into carotid atherosclerotic plaque
    Baocheng Chu
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    Circulation 113:e660-1. 2006
  3. ncbi request reprint Determination of carotid artery atherosclerotic lesion type and distribution in hypercholesterolemic patients with moderate carotid stenosis using noninvasive magnetic resonance imaging
    Baocheng Chu
    Department of Radiology, Box 357115, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA
    Stroke 35:2444-8. 2004
    ....
  4. ncbi request reprint Feasibility of in vivo, multicontrast-weighted MR imaging of carotid atherosclerosis for multicenter studies
    Baocheng Chu
    Department of Radiology, University of Washington, Seattle, Washington 98195, USA
    J Magn Reson Imaging 21:809-17. 2005
    ..To test the image quality (ImQ) and interscan coverage of MRI for measuring carotid atherosclerosis across multiple centers...
  5. ncbi request reprint Images in cardiovascular medicine. Detection of carotid atherosclerotic plaque ulceration, calcification, and thrombosis by multicontrast weighted magnetic resonance imaging
    Baocheng Chu
    Department of Radiology, University of Washington, 1959 NE Pacific St, Seattle, WA 98195, USA
    Circulation 112:e3-4. 2005
  6. ncbi request reprint Reproducibility of carotid atherosclerotic lesion type characterization using high resolution multicontrast weighted cardiovascular magnetic resonance
    Baocheng Chu
    Department of Radiology, University of Washington Medical Center, Seattle, Washington 98195, USA
    J Cardiovasc Magn Reson 8:793-9. 2006
    ..Cardiovascular magnetic resonance (CMR) can characterize carotid atherosclerosis. The purpose of this study is to evaluate reader agreement of carotid atherosclerotic lesion types by CMR...
  7. pmc Quantitative evaluation of high intensity signal on MIP images of carotid atherosclerotic plaques from routine TOF-MRA reveals elevated volumes of intraplaque hemorrhage and lipid rich necrotic core
    Kiyofumi Yamada
    Department of Radiology, University of Washington, Seattle, WA 98109 4325, USA
    J Cardiovasc Magn Reson 14:81. 2012
    ..The aim of this study was to evaluate the quantitative relationships between high intensity signals (HIS) in the plaque on TOF-MRA and IPH or LRNC volumes as measured by multicontrast weighted CMR...
  8. pmc Magnetic [corrected] resonance imaging [corrected] features of the disruption-prone and the disrupted carotid plaque
    Baocheng Chu
    Vascular Imaging Laboratory, University of Washington, Seattle, Washington 98109, USA
    JACC Cardiovasc Imaging 2:883-96. 2009
    ..This pictorial essay illustrates the capability of CMR for identifying features of disruption-prone and disrupted atherosclerotic carotid plaques...
  9. ncbi request reprint Intra- and interreader reproducibility of magnetic resonance imaging for quantifying the lipid-rich necrotic core is improved with gadolinium contrast enhancement
    Norihide Takaya
    Department of Radiology, University of Washington, Seattle, Washington, USA
    J Magn Reson Imaging 24:203-10. 2006
    ....
  10. doi request reprint Effect of rosuvastatin therapy on carotid plaque morphology and composition in moderately hypercholesterolemic patients: a high-resolution magnetic resonance imaging trial
    Hunter R Underhill
    Department of Radiology, University of Washington, Seattle, WA 98109, USA
    Am Heart J 155:584.e1-8. 2008
    ..Magnetic resonance imaging (MRI) can noninvasively assess changes in atherosclerotic plaque morphology and composition. The ORION trial assessed the effects of rosuvastatin on carotid plaque volume and composition...
  11. pmc Predictors of carotid atherosclerotic plaque progression as measured by noninvasive magnetic resonance imaging
    Tobias Saam
    Department of Radiology, University of Washington, Seattle, WA, USA
    Atherosclerosis 194:e34-42. 2007
    ..Findings from this study suggest that increased normalized wall index and the use of statin therapy are associated with reduced rates of plaque progression amongst individuals with advanced, asymptomatic carotid atherosclerosis...
  12. ncbi request reprint Sample size calculation for clinical trials using magnetic resonance imaging for the quantitative assessment of carotid atherosclerosis
    Tobias Saam
    Department of Radiology, University of Washington, Seattle, Washington 98195, USA
    J Cardiovasc Magn Reson 7:799-808. 2005
    ..The percent lipid-rich/necrotic core (%LR/NC) and calcification (%Ca) were measured as a proportion of the vessel wall. For %LR/NC and %Ca, only those subjects that exhibited LR/NC or Ca components were used in the analysis...
  13. doi request reprint Scan-rescan reproducibility of carotid atherosclerotic plaque morphology and tissue composition measurements using multicontrast MRI at 3T
    Feiyu Li
    Department of Radiology, University of Washington, Seattle, Washington 98109, USA
    J Magn Reson Imaging 31:168-76. 2010
    ..To evaluate interscan reproducibility of both vessel morphology and tissue composition measurements of carotid atherosclerosis using a fast, optimized, 3T multicontrast protocol...
  14. pmc Carotid plaque morphology and composition: initial comparison between 1.5- and 3.0-T magnetic field strengths
    Hunter R Underhill
    Department of Radiology, University of Washington, 815 Mercer St, Box 358050, Seattle, WA 98109, USA
    Radiology 248:550-60. 2008
    ..To prospectively compare the interpretation and quantification of carotid vessel wall morphology and plaque composition at 1.5-T with those at 3.0-T magnetic resonance (MR) imaging...
  15. pmc The added value of longitudinal black-blood cardiovascular magnetic resonance angiography in the cross sectional identification of carotid atherosclerotic ulceration
    Wei Yu
    Department of Radiology, University of Washington, Seattle, WA, USA
    J Cardiovasc Magn Reson 11:31. 2009
    ..This study evaluates the efficacy of adding longitudinal black-blood (BB) cardiovascular magnetic resonance (CMR) angiography to cross-sectional CMR images in the identification of carotid atherosclerotic ulceration...
  16. pmc Carotid artery atherosclerosis: effect of intensive lipid therapy on the vasa vasorum--evaluation by using dynamic contrast-enhanced MR imaging
    Li Dong
    Department of Radiology, University of Washington School of Medicine, 815 Mercer St, Seattle, WA 98109, USA
    Radiology 260:224-31. 2011
    ..To investigate whether short-term, intensive lipid therapy leads to changes in microvascular characteristics, as measured by using dynamic contrast material-enhanced (DCE) magnetic resonance (MR) imaging...
  17. pmc MR imaging of carotid plaque composition during lipid-lowering therapy a prospective assessment of effect and time course
    Xue Qiao Zhao
    Department of Medicine, Division of Cardiology, University of Washington, Seattle, Washington, USA
    JACC Cardiovasc Imaging 4:977-86. 2011
    ..The purpose of this study was to test the lipid depletion hypothesis and to establish the time course of change in carotid plaque morphology and composition during lipid therapy using high-resolution magnetic resonance imaging (MRI)...
  18. ncbi request reprint The vulnerable, or high-risk, atherosclerotic plaque: noninvasive MR imaging for characterization and assessment
    Tobias Saam
    Department of Radiology, University of Washington, Seattle, Washington, USA
    Radiology 244:64-77. 2007
    ..The use of MR imaging in animal models and in human disease in various vascular beds, particularly the carotid arteries, is presented...
  19. ncbi request reprint Hemorrhage in the atherosclerotic carotid plaque: a high-resolution MRI study
    Baocheng Chu
    Department of Radiology, University of Washington, USA
    Stroke 35:1079-84. 2004
    ..The aim of this study was to develop criteria for the identification of the stages of intraplaque hemorrhage using high-resolution MRI...
  20. ncbi request reprint In vivo quantitative measurement of intact fibrous cap and lipid-rich necrotic core size in atherosclerotic carotid plaque: comparison of high-resolution, contrast-enhanced magnetic resonance imaging and histology
    Jianming Cai
    Department of Radiology, University of Washington, Seattle, WA, USA
    Circulation 112:3437-44. 2005
    ..The goal of this study was to assess whether CEMRI can be used to accurately measure the dimensions of the intact FC and LR-NC...
  21. doi request reprint Discriminating carotid atherosclerotic lesion severity by luminal stenosis and plaque burden: a comparison utilizing high-resolution magnetic resonance imaging at 3.0 Tesla
    Xihai Zhao
    Department of Radiology, University of Washington, Seattle, WA 98109, USA
    Stroke 42:347-53. 2011
    ..To determine associations between stenosis, measures of plaque burden, and compositional features of carotid atherosclerosis, including high-risk features of intraplaque hemorrhage (IPH) and surface disruption...
  22. ncbi request reprint MRI of atherosclerosis in clinical trials
    Chun Yuan
    Department of Radiology, University of Washington, Seattle, WA 98195, USA
    NMR Biomed 19:636-54. 2006
    ..Also, the results of validation studies for measuring lesion size, composition and inflammation will be summarized. Finally, the status of several clinical trials involving MRI of atherosclerosis will be reviewed...
  23. ncbi request reprint Association between carotid plaque characteristics and subsequent ischemic cerebrovascular events: a prospective assessment with MRI--initial results
    Norihide Takaya
    Department of Radiology, University of Washington, Seattle, WA, USA
    Stroke 37:818-23. 2006
    ..We tested the hypothesis that the characteristics of carotid plaque, as assessed by MRI, are possible predictors of future ipsilateral cerebrovascular events...
  24. pmc Carotid plaque assessment using fast 3D isotropic resolution black-blood MRI
    Niranjan Balu
    Department of Radiology, University of Washington, Seattle, Washington 98019, USA
    Magn Reson Med 65:627-37. 2011
    ..3D-MERGE is a promising new tool for fast and accurate plaque burden assessment in patients with atherosclerotic plaque...
  25. ncbi request reprint Testing the hypothesis of atherosclerotic plaque lipid depletion during lipid therapy by magnetic resonance imaging: study design of Carotid Plaque Composition Study
    Xue Qiao Zhao
    Division of Cardiology, Department of Medicine, University of Washington, Seattle, WA 98103, USA
    Am Heart J 154:239-46. 2007
    ..In vivo testing of the lipid depletion hypothesis in human beings during lipid-modifying therapy has not been possible until recent developments in magnetic resonance imaging (MRI)...
  26. pmc Comparison between 2D and 3D high-resolution black-blood techniques for carotid artery wall imaging in clinically significant atherosclerosis
    Niranjan Balu
    Department of Bioengineering, University of Washington, Seattle, Washington, USA
    J Magn Reson Imaging 27:918-24. 2008
    ..To compare two- (2D) and three-dimensional (3D) black-blood imaging methods for morphological measurements of the carotid artery wall and atherosclerotic plaque...
  27. ncbi request reprint Magnetic resonance imaging of carotid atherosclerosis: plaque analysis
    William Kerwin
    Department of Radiology, University of Washington, Seattle, WA 98109, USA
    Top Magn Reson Imaging 18:371-8. 2007
    ..The purpose of this investigation was to assess the performance of CASCADE compared with manual outlining...
  28. ncbi request reprint Effect of contrast enhancement on the measurement of carotid arterial lumen and wall volume using MRI
    Binh An P Phan
    Department of Medicine, University of Washington, Seattle, Washington 98103 8771, USA
    J Magn Reson Imaging 23:481-5. 2006
    ..To investigate whether gadolinium (Gd)-based contrast enhancement (CE) affects high-resolution magnetic resonance imaging (MRI) measurements of carotid arterial wall volume...
  29. ncbi request reprint Presence of intraplaque hemorrhage stimulates progression of carotid atherosclerotic plaques: a high-resolution magnetic resonance imaging study
    Norihide Takaya
    Department of Radiology, University of Washington, Seattle, USA
    Circulation 111:2768-75. 2005
    ..We have shown that MRI can accurately identify carotid intraplaque hemorrhage and precisely measure plaque volume. We tested the hypothesis that hemorrhage into carotid atheroma stimulates plaque progression...
  30. pmc Improvements in carotid plaque imaging using a new eight-element phased array coil at 3T
    Niranjan Balu
    Department of Radiology, University of Washington, Seattle, Washington, USA
    J Magn Reson Imaging 30:1209-14. 2009
    ..To design and compare an eight-channel phased array (PA) coil for carotid imaging to an established four-channel PA design at 3T...
  31. ncbi request reprint Automated in vivo segmentation of carotid plaque MRI with Morphology-Enhanced probability maps
    Fei Liu
    Department of Radiology, University of Washington, Seattle, WA 98109, USA
    Magn Reson Med 55:659-68. 2006
    ..71, 0.76, 0.33, and 0.78, respectively. These results show that in vivo automatic segmentation of carotid MRI is feasible and comparable to or possibly more accurate than manual review for quantifying plaque composition...
  32. ncbi request reprint Prevalence of compositional features in subclinical carotid atherosclerosis determined by high-resolution magnetic resonance imaging in chinese patients with coronary artery disease
    Xihai Zhao
    Department of Radiology, University of Washington, 815 Mercer Street, Box 358050, Seattle, WA 98109, USA
    Stroke 41:1157-62. 2010
    ..This study sought to determine the prevalence of compositional features in subclinical carotid atherosclerosis by MRI in CAD patients...
  33. ncbi request reprint Serial MRI of carotid plaque burden: influence of subject repositioning on measurement precision
    Niranjan Balu
    Department of Bioengineering, Vascular Imaging Laboratory, University of Washington, Seattle, Washington 98109, USA
    Magn Reson Med 57:592-9. 2007
    ..Orientation variability was the single most important factor that affected reproducibility, which suggests that methods are needed to obtain consistent orientation of the artery relative to the image plane...
  34. ncbi request reprint Association of high-density lipoprotein levels and carotid atherosclerotic plaque characteristics by magnetic resonance imaging
    Binh An P Phan
    Division of Cardiology, Department of Medicine, University of Washington, 1914 N 34th Street, Suite 105, Seattle, WA, 98103 8771, USA
    Int J Cardiovasc Imaging 23:337-42. 2007
    ..81 +/- 19 mm(3), P = 0.05) compared with patients with HDL levels > 35 mg/dL. Among CAD patients, low HDL-C levels were significantly associated with increased carotid atherosclerotic plaque burden and lipid content by MRI...
  35. pmc Differences in carotid arterial morphology and composition between individuals with and without obstructive coronary artery disease: a cardiovascular magnetic resonance study
    Hunter R Underhill
    Department of Radiology University of Washington, Seattle, WA, USA
    J Cardiovasc Magn Reson 10:31. 2008
    ....
  36. pmc The association of lesion eccentricity with plaque morphology and components in the superficial femoral artery: a high-spatial-resolution, multi-contrast weighted CMR study
    Feiyu Li
    Department of Radiology, University of Washington, Seattle, WA, USA
    J Cardiovasc Magn Reson 12:37. 2010
    ..This study investigated associations of plaque eccentricity with plaque components and morphology in the proximal superficial femoral artery using cardiovascular magnetic resonance (CMR)...
  37. pmc Time-efficient black blood RCA wall imaging at 3T using improved motion sensitized driven equilibrium (iMSDE): feasibility and reproducibility
    Jinnan Wang
    Department of Radiology, University of Washington, Seattle, Washington, United States of America
    PLoS ONE 6:e26567. 2011
    ..The aim of this study was to explore the feasibility and reproducibility of a time-efficient coronary vessel wall measurement approach using an improved motion-sensitized driven equilibrium (iMSDE) pulse sequence...
  38. ncbi request reprint Improved suppression of plaque-mimicking artifacts in black-blood carotid atherosclerosis imaging using a multislice motion-sensitized driven-equilibrium (MSDE) turbo spin-echo (TSE) sequence
    Jinnan Wang
    Department of Bioengineering, University of Washington, Seattle, Washington, USA
    Magn Reson Med 58:973-81. 2007
    ....
  39. doi request reprint Changes in measured size of atherosclerotic plaque calcifications in dual-energy CT of ex vivo carotid endarterectomy specimens: effect of monochromatic keV image reconstructions
    Lorenzo Mannelli
    Departments of Radiology, University of Washington, Seattle, WA, USA
    Eur Radiol 23:367-74. 2013
    ..The aim of this study was to compare the size of the calcifications measured on the different keV images to a histological standard...
  40. doi request reprint Imaging and cell targeting characteristics of magnetic nanoparticles modified by a functionalizable zwitterionic polymer with adhesive 3,4-dihydroxyphenyl-l-alanine linkages
    Lei Zhang
    Department of Chemical Engineering, University of Washington, Box 351750, Seattle, WA 98195, United States
    Biomaterials 31:6582-8. 2010
    ....
  41. ncbi request reprint Determination of nanoparticle vehicle unpackaging by MR imaging of a T(2) magnetic relaxation switch
    In Kyu Park
    Department of Bioengineering, University of Washington W H Foege Building, Room N530P, Box 355061, 1705 NE Pacific Street, Seattle, WA 98195, USA
    Biomaterials 29:724-32. 2008
    ..Thus, this material integrates capabilities of gene delivery with magnetic resonance (MR) contrast and also provides an MR-based read-out for vector unpackaging...
  42. pmc Immune responses to AAV in canine muscle monitored by cellular assays and noninvasive imaging
    Zejing Wang
    Program in Transplantation Biology, Division of Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Mol Ther 18:617-24. 2010
    ..These assays should be incorporated into future human clinical trials of AAV gene therapy to monitor immune responses...
  43. doi request reprint Prevalence of American Heart Association type VI carotid atherosclerotic lesions identified by magnetic resonance imaging for different levels of stenosis as measured by duplex ultrasound
    Tobias Saam
    Department of Clinical Radiology, University of Munich, Grosshadern Campus, Munich, Germany
    J Am Coll Cardiol 51:1014-21. 2008
    ....
  44. ncbi request reprint Reader and platform reproducibility for quantitative assessment of carotid atherosclerotic plaque using 1.5T Siemens, Philips, and General Electric scanners
    Tobias Saam
    Department of Clinical Radiology, University of Munich, Munich, Germany
    J Magn Reson Imaging 26:344-52. 2007
    ..To evaluate the platform and reader reproducibility of quantitative carotid plaque measurements...