Demetra D Christou

Summary

Affiliation: University of Colorado
Country: USA

Publications

  1. ncbi request reprint Baroreflex buffering in sedentary and endurance exercise-trained healthy men
    Demetra D Christou
    Department of Kinesiology and Applied Physiology, University of Colorado at Boulder, UCB 354, Boulder, Colo 80309, USA
    Hypertension 41:1219-22. 2003
  2. ncbi request reprint Women have lower tonic autonomic support of arterial blood pressure and less effective baroreflex buffering than men
    Demetra D Christou
    Department of Integrative Physiology, University of Colorado at Boulder, 354 UCB, Boulder, CO 80309, USA
    Circulation 111:494-8. 2005
  3. ncbi request reprint Fatness is a better predictor of cardiovascular disease risk factor profile than aerobic fitness in healthy men
    Demetra D Christou
    Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
    Circulation 111:1904-14. 2005
  4. ncbi request reprint Increased abdominal-to-peripheral fat distribution contributes to altered autonomic-circulatory control with human aging
    Demetra D Christou
    Dept of Integrative Physiology, University of Colorado at Boulder, UCB 354, Boulder, CO 80309, USA
    Am J Physiol Heart Circ Physiol 287:H1530-7. 2004
  5. ncbi request reprint Baroreflex buffering is reduced with age in healthy men
    Pamela Parker Jones
    Department of Kinesiology and Applied Physiology, University of Colorado at Boulder, UCB 354, Boulder, CO 80309, USA
    Circulation 107:1770-4. 2003
  6. ncbi request reprint Adiposity contributes to differences in left ventricular structure and diastolic function with age in healthy men
    Phillip E Gates
    Department of Integrative Physiology, University of Colorado, Boulder, Colorado 80309, USA
    J Clin Endocrinol Metab 88:4884-90. 2003
  7. pmc Decreased maximal heart rate with aging is related to reduced {beta}-adrenergic responsiveness but is largely explained by a reduction in intrinsic heart rate
    Demetra D Christou
    Department of Intergrative Physiology, University of Colorado, Boulder, Colorado, USA
    J Appl Physiol 105:24-9. 2008
  8. ncbi request reprint High energy flux mediates the tonically augmented beta-adrenergic support of resting metabolic rate in habitually exercising older adults
    Christopher Bell
    Department of Integrative Physiology, 354UCB, University of Colorado, Boulder, CO 80309 0354, USA
    J Clin Endocrinol Metab 89:3573-8. 2004
  9. pmc Protein expression in vascular endothelial cells obtained from human peripheral arteries and veins
    Annemarie E Silver
    Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
    J Vasc Res 47:1-8. 2010
  10. ncbi request reprint Overweight and obese humans demonstrate increased vascular endothelial NAD(P)H oxidase-p47(phox) expression and evidence of endothelial oxidative stress
    Annemarie E Silver
    Department of Integrative Physiology, University of Colorado at Boulder, Boulder, CO 80309, USA
    Circulation 115:627-37. 2007

Detail Information

Publications10

  1. ncbi request reprint Baroreflex buffering in sedentary and endurance exercise-trained healthy men
    Demetra D Christou
    Department of Kinesiology and Applied Physiology, University of Colorado at Boulder, UCB 354, Boulder, Colo 80309, USA
    Hypertension 41:1219-22. 2003
    ..These results support the concept that habitual vigorous endurance exercise does not modulate in vivo baroreflex buffering in healthy humans...
  2. ncbi request reprint Women have lower tonic autonomic support of arterial blood pressure and less effective baroreflex buffering than men
    Demetra D Christou
    Department of Integrative Physiology, University of Colorado at Boulder, 354 UCB, Boulder, CO 80309, USA
    Circulation 111:494-8. 2005
    ..Short-term and tonic regulation of arterial blood pressure (BP) differ in premenopausal women and men of similar age. The autonomic nervous system (ANS) plays a critical role in BP regulation...
  3. ncbi request reprint Fatness is a better predictor of cardiovascular disease risk factor profile than aerobic fitness in healthy men
    Demetra D Christou
    Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
    Circulation 111:1904-14. 2005
    ..We sought to determine whether fatness or fitness better predicted traditional CVD risk factors in men with broad fatness, aerobic fitness, and age ranges using 3 expressions of adiposity...
  4. ncbi request reprint Increased abdominal-to-peripheral fat distribution contributes to altered autonomic-circulatory control with human aging
    Demetra D Christou
    Dept of Integrative Physiology, University of Colorado at Boulder, UCB 354, Boulder, CO 80309, USA
    Am J Physiol Heart Circ Physiol 287:H1530-7. 2004
    ..These results may help explain how changes in body fat distribution with advancing age are linked to impairments in circulatory control...
  5. ncbi request reprint Baroreflex buffering is reduced with age in healthy men
    Pamela Parker Jones
    Department of Kinesiology and Applied Physiology, University of Colorado at Boulder, UCB 354, Boulder, CO 80309, USA
    Circulation 107:1770-4. 2003
    ..Baroreflex buffering is an important mechanism in arterial blood pressure control. The effect of healthy (physiological) aging on tonic baroreflex buffering in humans is unknown...
  6. ncbi request reprint Adiposity contributes to differences in left ventricular structure and diastolic function with age in healthy men
    Phillip E Gates
    Department of Integrative Physiology, University of Colorado, Boulder, Colorado 80309, USA
    J Clin Endocrinol Metab 88:4884-90. 2003
    ..We conclude that increasing adiposity contributes to the LV remodeling/reduced diastolic function that occurs with aging in healthy men...
  7. pmc Decreased maximal heart rate with aging is related to reduced {beta}-adrenergic responsiveness but is largely explained by a reduction in intrinsic heart rate
    Demetra D Christou
    Department of Intergrative Physiology, University of Colorado, Boulder, Colorado, USA
    J Appl Physiol 105:24-9. 2008
    ..Our findings indicate that, together, reductions in HR(int) and chronotropic responsiveness to beta-adrenergic stimulation largely explain decreases in HR(max) with aging, with the reduction in HR(int) playing by far the greatest role...
  8. ncbi request reprint High energy flux mediates the tonically augmented beta-adrenergic support of resting metabolic rate in habitually exercising older adults
    Christopher Bell
    Department of Integrative Physiology, 354UCB, University of Colorado, Boulder, CO 80309 0354, USA
    J Clin Endocrinol Metab 89:3573-8. 2004
    ..Maintenance of high energy flux via regular exercise may be an effective strategy for maintaining energy expenditure and preventing age-associated obesity...
  9. pmc Protein expression in vascular endothelial cells obtained from human peripheral arteries and veins
    Annemarie E Silver
    Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
    J Vasc Res 47:1-8. 2010
    ..Thus, EC collected from peripheral veins may provide a useful surrogate for EC obtained from arteries for measurements of EC protein expression in humans...
  10. ncbi request reprint Overweight and obese humans demonstrate increased vascular endothelial NAD(P)H oxidase-p47(phox) expression and evidence of endothelial oxidative stress
    Annemarie E Silver
    Department of Integrative Physiology, University of Colorado at Boulder, Boulder, CO 80309, USA
    Circulation 115:627-37. 2007
    ..Obesity may alter vascular endothelial cell protein expression (VECPE) of molecules that influence susceptibility to atherosclerosis...