Research Topics
| Chadwick W ChristineSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Development of Parkinson's disease in patients with NarcolepsyChadwick W Christine
Department of Neurology, University of California, San Francisco, 400 Parnassus Avenue, Box 0348, San Francisco, CA 94143, USA
J Neural Transm 119:697-9. 2012..Although preliminary, this observation raises the possibility that some factors intrinsic to narcolepsy or its treatment may be a risk factor for PD...
The neurophysiology and effect of deep brain stimulation in a patient with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonismChadwick W Christine
Department of Neurology, University of California, San Francisco, CA, USA
J Neurosurg 110:234-8. 2009..This unique case has important implications for translational research that employs the MPTP-primate model for symptomatic therapy in PD...
Parkinsonism in patients with a history of amphetamine exposureChadwick W Christine
Department of Neurology, University of California, San Francisco, CA 94143, USA
Mov Disord 25:228-31. 2010....
Effects of unilateral subthalamic and pallidal deep brain stimulation on fine motor functions in Parkinson's diseaseKen Nakamura
Department of Neurology, University of California, San Francisco, CA, USA
Mov Disord 22:619-26. 2007..Our findings suggest that DBS of the STN or GPi results in a similar improvement in hand movements at short-term follow-up. Preoperative medication responsiveness predicts improvement in some but not other motor tasks...
Pedunculopontine nucleus deep brain stimulation in a patient with primary progressive freezing gait disorderJill L Ostrem
Department of Neurology, University of California San Francisco, Center for the Surgical Treatment of Movement Disorders, San Francisco, CA 94143, USA
Stereotact Funct Neurosurg 88:51-5. 2010..We report here on our experience with PPN DBS in treating a 76-year-old man with medication-refractory PPFG...
Implantation of deep brain stimulators into the subthalamic nucleus: technical approach and magnetic resonance imaging-verified lead locationsPhilip A Starr
Department of Neurological Surgery, University of California, San Francisco 94143, USA
J Neurosurg 97:370-87. 2002..The authors present the technical approach used to implant 76 stimulators into the STNs of patients with PD and the lead locations, which were verified on postoperative magnetic resonance (MR) images...
Qualitative imaging of adeno-associated virus serotype 2-human aromatic L-amino acid decarboxylase gene therapy in a phase I study for the treatment of Parkinson diseaseFrancisco Valles
Movement Disorder Research Program, Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94103, USA
Neurosurgery 67:1377-85. 2010....
Long-term evaluation of a phase 1 study of AADC gene therapy for Parkinson's diseaseGabriele Mittermeyer
Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA
Hum Gene Ther 23:377-81. 2012..These data indicate stable transgene expression over 4 years after vector delivery and continued safety, but emphasize the need for a controlled efficacy trial and the use of a higher vector dose...
Cognitive and neuropsychiatric profile of the synucleinopathies: Parkinson disease, dementia with Lewy bodies, and multiple system atrophyAimee W Kao
Department of Neurology, University of California San Francisco, 94143, USA
Alzheimer Dis Assoc Disord 23:365-70. 2009..PD, MSA, and DLB groups have similar neuropsychiatric profiles of increased depression and anxiety. Similar underlying alpha-synuclein pathology may contribute to these shared features...
Hospitalization in Parkinson disease: a survey of National Parkinson Foundation CentersKelvin L Chou
Department of Neurology, University of Michigan, Ann Arbor, MI 48109 5316, USA
Parkinsonism Relat Disord 17:440-5. 2011..To explore current practices and opinions regarding hospital management of Parkinson disease (PD) patients in specialized PD Centers...
Clinical differentiation of parkinsonian syndromes: prognostic and therapeutic relevanceChadwick W Christine
Department of Neurology, School of Medicine, University of California, San Francisco 94143, USA
Am J Med 117:412-9. 2004..Tests of autonomic function and brain imaging are often helpful in distinguishing these diseases...
