E A Chrischilles

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. pmc Incidence of and risk factors for community-associated Clostridium difficile infection: a nested case-control study
    Jennifer L Kuntz
    Center for Health Research, Kaiser Permanente Northwest, Portland, OR, USA
    BMC Infect Dis 11:194. 2011
  2. pmc Defining emergency department episodes by severity and intensity: A 15-year study of Medicare beneficiaries
    Brian Kaskie
    Department of Health Management and Policy, College of Public Health, The University of Iowa, Iowa City, Iowa, USA
    BMC Health Serv Res 10:173. 2010
  3. pmc Adverse events among the elderly receiving chemotherapy for advanced non-small-cell lung cancer
    Elizabeth A Chrischilles
    Department of Epidemiology, University of Iowa, Iowa City, IA 52242, USA
    J Clin Oncol 28:620-7. 2010
  4. ncbi request reprint Evaluation of the Iowa Medicaid pharmaceutical case management program
    Elizabeth A Chrischilles
    Health Effectiveness Research Center, Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    J Am Pharm Assoc (2003) 44:337-49. 2004
  5. ncbi request reprint Inappropriate medication use as a risk factor for self-reported adverse drug effects in older adults
    Elizabeth A Chrischilles
    Department of Epidemiology, College of Public Health, The University of Iowa, 200 Hawkins Drive, C21 J GH, Iowa City, IA 52242, USA
    J Am Geriatr Soc 57:1000-6. 2009
  6. ncbi request reprint Risk factors for adverse drug events in older adults with mobility limitations in the community setting
    Elizabeth Chrischilles
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    J Am Geriatr Soc 55:29-34. 2007
  7. ncbi request reprint Linking clinical variables to health-related quality of life in Parkinson's disease
    Elizabeth A Chrischilles
    Department of Epidemiology, College of Public Health, The University of Iowa, Iowa City, IA 52242, USA
    Parkinsonism Relat Disord 8:199-209. 2002
  8. ncbi request reprint The role of pharmacy computer systems in preventing medication errors
    Elizabeth A Chrischilles
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City 52242, USA
    J Am Pharm Assoc (Wash) 42:439-48. 2002
  9. ncbi request reprint Do practice guidelines augment drug utilisation review?
    E A Chrischilles
    Department of Preventive Medicine and Environmental Health, College of Medicine, University of Iowa, Iowa City, USA
    Pharmacoeconomics 12:648-66. 1997
  10. pmc The aftermath of hip fracture: discharge placement, functional status change, and mortality
    Suzanne E Bentler
    Department of Health Management and Policy, College of Public Health, University of Iowa, Iowa City, USA
    Am J Epidemiol 170:1290-9. 2009

Research Grants

  1. Pharmaceutical Case Management and Living Well with a Disability
    Elizabeth Chrischilles; Fiscal Year: 2007
  2. Personal Health Records and Elder Medication Use Quality
    Elizabeth Chrischilles; Fiscal Year: 2007

Detail Information

Publications45

  1. pmc Incidence of and risk factors for community-associated Clostridium difficile infection: a nested case-control study
    Jennifer L Kuntz
    Center for Health Research, Kaiser Permanente Northwest, Portland, OR, USA
    BMC Infect Dis 11:194. 2011
    ..The purpose of this study was to examine the epidemiology of CA-CDI, by estimating the incidence of CA-CDI and HA-CDI, identifying patient-related risk factors for CA-CDI, and describing adverse health outcomes of CA-CDI...
  2. pmc Defining emergency department episodes by severity and intensity: A 15-year study of Medicare beneficiaries
    Brian Kaskie
    Department of Health Management and Policy, College of Public Health, The University of Iowa, Iowa City, Iowa, USA
    BMC Health Serv Res 10:173. 2010
    ....
  3. pmc Adverse events among the elderly receiving chemotherapy for advanced non-small-cell lung cancer
    Elizabeth A Chrischilles
    Department of Epidemiology, University of Iowa, Iowa City, IA 52242, USA
    J Clin Oncol 28:620-7. 2010
    ..To describe chemotherapy use and adverse events (AEs) for advanced-stage, non-small-cell lung cancer (NSCLC) in community practice, including descriptions according to variation by age...
  4. ncbi request reprint Evaluation of the Iowa Medicaid pharmaceutical case management program
    Elizabeth A Chrischilles
    Health Effectiveness Research Center, Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    J Am Pharm Assoc (2003) 44:337-49. 2004
    ..To test the effect of pharmaceutical case management (PCM) on medication safety and health care utilization...
  5. ncbi request reprint Inappropriate medication use as a risk factor for self-reported adverse drug effects in older adults
    Elizabeth A Chrischilles
    Department of Epidemiology, College of Public Health, The University of Iowa, 200 Hawkins Drive, C21 J GH, Iowa City, IA 52242, USA
    J Am Geriatr Soc 57:1000-6. 2009
    ..To determine the association between inappropriate medication use and self-reported adverse drug effects (ADEs)...
  6. ncbi request reprint Risk factors for adverse drug events in older adults with mobility limitations in the community setting
    Elizabeth Chrischilles
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA 52242, USA
    J Am Geriatr Soc 55:29-34. 2007
    ..To investigate risk factors for self-reported adverse drug events (ADEs) in a cohort of annually surveyed Iowa Medicare beneficiaries with mobility limitations...
  7. ncbi request reprint Linking clinical variables to health-related quality of life in Parkinson's disease
    Elizabeth A Chrischilles
    Department of Epidemiology, College of Public Health, The University of Iowa, Iowa City, IA 52242, USA
    Parkinsonism Relat Disord 8:199-209. 2002
    ..Identify the point-in-time relationship between Parkinson's disease (PD) signs and symptoms and measures of health-related quality of life (HRQL)...
  8. ncbi request reprint The role of pharmacy computer systems in preventing medication errors
    Elizabeth A Chrischilles
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City 52242, USA
    J Am Pharm Assoc (Wash) 42:439-48. 2002
    ..To describe the controversies and review the evidence about computer-aided prospective drug utilization review (PDUR) systems...
  9. ncbi request reprint Do practice guidelines augment drug utilisation review?
    E A Chrischilles
    Department of Preventive Medicine and Environmental Health, College of Medicine, University of Iowa, Iowa City, USA
    Pharmacoeconomics 12:648-66. 1997
    ..We conclude that practice guidelines are a useful resource for augmenting DUR/DUE but that challenges to optimising their use include whether they can be kept current, acceptable and accessible to providers...
  10. pmc The aftermath of hip fracture: discharge placement, functional status change, and mortality
    Suzanne E Bentler
    Department of Health Management and Policy, College of Public Health, University of Iowa, Iowa City, USA
    Am J Epidemiol 170:1290-9. 2009
    ..Sex, age, dementia, and frailty were significantly associated with mortality. This is one of the few studies to prospectively capture these declines in functional status after hip fracture...
  11. pmc Was breast conserving surgery underutilized for early stage breast cancer? Instrumental variables evidence for stage II patients from Iowa
    John M Brooks
    Health Effectiveness Research Center, College of Pharmacy and the College of Public Health, University of Iowa, Iowa City 52242, USA
    Health Serv Res 38:1385-402. 2003
    ..DATA SOURCES/DATA SETTING: Secondary linked Iowa SEER Cancer Registry--Iowa Hospital Association discharge abstract data for women in Iowa with stage II breast cancer from 1989-1994...
  12. ncbi request reprint The impact of Parkinson's disease on health status, health expenditures, and productivity. Estimates from the National Medical Expenditure Survey
    L M Rubenstein
    Department of Preventive Medicine and Environmental Health, University of Iowa, Iowa City, USA
    Pharmacoeconomics 12:486-98. 1997
    ..There was also considerable variability in case-control groups, resulting in wide confidence intervals for the estimates...
  13. ncbi request reprint The usefulness of the Functional Status Questionnaire and Medical Outcomes Study Short Form in Parkinson's disease research
    L M Rubenstein
    Department of Preventive Medicine and Environmental Health, University of Iowa, Iowa City 52242, USA
    Qual Life Res 7:279-90. 1998
    ..Many of the HRQoL measures discriminate progressive stages of disease in this study group and distinguish those with complications of therapy from subjects without complications...
  14. ncbi request reprint Population-based assessment of hospitalizations for neutropenia from chemotherapy in older adults with non-Hodgkin's lymphoma (United States)
    Shari Chen-Hardee
    Department of Epidemiology, College of Public Health, The University of Iowa, Iowa City, IA, USA
    Cancer Causes Control 17:647-54. 2006
    ....
  15. ncbi request reprint The concurrent use of anticholinergics and cholinesterase inhibitors: rare event or common practice?
    Ryan M Carnahan
    Clinical and Administrative Pharmacy, College of Pharmacy, University of Iowa, Iowa City, USA
    J Am Geriatr Soc 52:2082-7. 2004
    ..To measure the prevalence of anticholinergic use cross-sectionally in patients receiving cholinesterase inhibitors and to describe change in use of anticholinergics upon inception of cholinesterase inhibitor treatment...
  16. ncbi request reprint System for exchanging information among pharmacists in different practice environments
    A K Kuehl
    Department of Preventive Medicine, University of Iowa, Iowa City 52242, USA
    J Am Pharm Assoc (Wash) 38:317-24. 1998
    ..A system for exchanging patient information among hospital, long-term-care (LTC), and ambulatory care pharmacies is described, and the influence of that system on pharmacist interventions is reported...
  17. pmc Hospital episodes and physician visits: the concordance between self-reports and medicare claims
    Fredric D Wolinsky
    Iowa City VA Health Care System, Iowa City, Iowa, USA
    Med Care 45:300-7. 2007
    ..Health services use typically is examined using either self-reports or administrative data, but the concordance between the 2 is not well established...
  18. pmc An interpersonal continuity of care measure for Medicare Part B claims analyses
    Fredric D Wolinsky
    Iowa City Veterans Affairs Medical Center, Iowa, USA
    J Gerontol B Psychol Sci Soc Sci 62:S160-8. 2007
    ..This article presents an interpersonal continuity of care measure...
  19. pmc Prior hospitalization and the risk of heart attack in older adults: a 12-year prospective study of Medicare beneficiaries
    Fredric D Wolinsky
    Department of Health Management, University of Iowa, 200 Hawkins Drive, E 205 General Hospital, Iowa City, IA 52242, USA
    J Gerontol A Biol Sci Med Sci 65:769-77. 2010
    ..We investigated whether prior hospitalization was a risk factor for heart attacks among older adults in the survey on Assets and Health Dynamics among the Oldest Old...
  20. pmc Emergency department utilization patterns among older adults
    Fredric D Wolinsky
    The Iowa City VA Medical Center, Iowa, USA
    J Gerontol A Biol Sci Med Sci 63:204-9. 2008
    ..We identified 4-year (2 years before and 2 years after the index [baseline] interview) ED use patterns in older adults and the factors associated with them...
  21. pmc A cluster randomized trial to evaluate physician/pharmacist collaboration to improve blood pressure control
    Barry L Carter
    Division of Clinical and Administrative Pharmacy, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA
    J Clin Hypertens (Greenwich) 10:260-71. 2008
    ..9; CI, 3.8-20.7; P<.001). Physician/pharmacist collaboration achieved significantly better mean BP values and overall BP control rates, primarily by intensification of medication therapy and improving patient adherence...
  22. pmc Recent hospitalization and the risk of hip fracture among older Americans
    Fredric D Wolinsky
    University of Iowa, 200 Hawkins Drive, E 205 General Hospital, Iowa City, IA 52242, USA
    J Gerontol A Biol Sci Med Sci 64:249-55. 2009
    ..We identified hip fracture risks in a prospective national study...
  23. pmc A 12-year prospective study of stroke risk in older Medicare beneficiaries
    Fredric D Wolinsky
    Center for Research on the Implementation of Innovative Strategies into Practice, Iowa City Veterans Administration Medical Center, Iowa City, Iowa, USA
    BMC Geriatr 9:17. 2009
    ..Stroke costs about $66B annually in the US, and also results in serious, long-term disability. Therefore, it is prudent to identify all possible risk factors and their effects so that appropriate intervention points may be targeted...
  24. pmc Physician and pharmacist collaboration to improve blood pressure control
    Barry L Carter
    Department of Pharmacy Practice and Science, College of Pharmacy, University of Iowa, Room 527, Iowa City, IA 52242, USA
    Arch Intern Med 169:1996-2002. 2009
    ..The objective of this study was to evaluate if a physician and pharmacist collaborative model in community-based medical offices could improve BP control...
  25. pmc Continuity of care with a primary care physician and mortality in older adults
    Fredric D Wolinsky
    Departments of Health Management and Policy and General Internal Medicine, The University of Iowa, 200 Hawkins Drive, E 205 General Hospital, Iowa City, IA 52242, USA
    J Gerontol A Biol Sci Med Sci 65:421-8. 2010
    ..We examined whether older adults who had continuity of care with a primary care physician (PCP) had lower mortality...
  26. doi request reprint A new method to isolate local-area practice styles in prescription use as the basis for instrumental variables in comparative effectiveness research
    Gang Fang
    Department of Pharmacy Practice and Science, College of Pharmacy, University of Iowa, Iowa City, IA 52242, USA
    Med Care 48:710-7. 2010
    ..The portion of geographic variation in prescription drug use representing "practice style" may provide natural experiments as instrumental variables to address this knowledge gap...
  27. pmc Deterioration of blood pressure control after discontinuation of a physician-pharmacist collaborative intervention
    Barry L Carter
    Department of Pharmacy Practice and Science, College of Pharmacy, University of Iowa, Iowa City, Iowa 52242, USA
    Pharmacotherapy 30:228-35. 2010
    ..To assess blood pressure control after discontinuation of a physician-pharmacist collaborative intervention...
  28. ncbi request reprint Extent of services provided by pharmacists in the Iowa Medicaid Pharmaceutical Case Management program
    Barry L Carter
    Division of Clinical and Administrative Pharmacy, Department of Family Medicine, College of Medicine, University of Iowa, lowa City 52242, USA
    J Am Pharm Assoc (Wash) 43:24-33. 2003
    ....
  29. pmc Demographic differences in incidence for pituitary adenoma
    Bradley D McDowell
    Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA, 52242, USA
    Pituitary 14:23-30. 2011
    ..There are several potential explanations for this finding with some evidence that at least part of the effect may be due to differential diagnosis between races...
  30. ncbi request reprint Factors associated with early termination of CHOP therapy and the impact on survival among patients with chemosensitive intermediate-grade non-Hodgkin's lymphoma
    Elizabeth A Chrischilles
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City 52242, USA
    Cancer Control 10:396-403. 2003
    ....
  31. ncbi request reprint Days of prophylactic filgrastim use to reduce febrile neutropenia in patients with non-Hodgkin's lymphoma treated with chemotherapy
    Shane D Scott
    Holden Comprehensive Cancer Center, University of Iowa, 200 Hawkins Dr 5974 JPP, Iowa City, IA 52242, USA
    J Manag Care Pharm 9:15-21. 2003
    ..s lymphoma (NHL) treated with chemotherapy, but differences in days of therapy and mode (primary or secondary) of prophylaxis may affect clinical outcomes...
  32. ncbi request reprint Cost-effectiveness of tamsulosin, doxazosin, and terazosin in the treatment of benign prostatic hyperplasia
    Robert L Ohsfeldt
    Department of Health Management and Policy, College of Public Health, University of Iowa, Iowa City, Iowa 52242, USA
    J Manag Care Pharm 10:412-22. 2004
    ..To evaluate the cost-effectiveness of tamsulosin, doxazosin, or terazosin as initial treatments for moderate benign prostatic hyperplasia (BPH) over a 3-year time horizon from a health-system-payer perspective...
  33. ncbi request reprint Heterogeneity and the interpretation of treatment effect estimates from risk adjustment and instrumental variable methods
    John M Brooks
    Program in Pharmaceutical Socioeconomics, College of Pharmacy, University of Iowa, Iowa City, Iowa, USA
    Med Care 45:S123-30. 2007
    ..We demonstrate these contrasts by examining the effect of breast conserving surgery plus irradiation (BCSI) relative to mastectomy on early stage breast cancer (ESBC) survival...
  34. pmc Asthma and farm exposures in a cohort of rural Iowa children
    James A Merchant
    Department of Occupational and Environmental Health, University of Iowa College of Public Health, Iowa City, Iowa, USA
    Environ Health Perspect 113:350-6. 2005
    ....
  35. ncbi request reprint Effect of clinical characteristics on neutropenia-related inpatient costs among newly diagnosed non-Hodgkin's lymphoma cases during first-course chemotherapy
    Elizabeth A Chrischilles
    Health Effectiveness Research Center, College of Public Health, University of Iowa, Iowa City, 52242, USA
    Pharmacotherapy 25:668-75. 2005
    ..To estimate the costs of hospitalization for neutropenia among chemotherapy-treated patients with newly diagnosed non-Hodgkin's lymphoma and to assess baseline patient factors associated with these costs...
  36. pmc A cluster-randomized effectiveness trial of a physician-pharmacist collaborative model to improve blood pressure control
    Barry L Carter
    Department of Pharmacy Practice and Science, College of Pharmacy, University of Iowa, Iowa City, Iowa 52242, USA
    Circ Cardiovasc Qual Outcomes 3:418-23. 2010
    ..CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT00935077...
  37. ncbi request reprint Economic and health-related quality of life considerations of new therapies in Parkinson's disease
    L M Rubenstein
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, 52242, USA
    Pharmacoeconomics 19:729-52. 2001
    ..Longer term effectiveness of many treatment strategies, and the usefulness of HR-QOL instruments to assess these treatments for individual patients over time, are critical areas for future research...
  38. ncbi request reprint System for exchanging information among pharmacists in different practice environments
    A K Kuehl
    Department of Preventive Medicine, University of Iowa, Iowa City 52242, USA
    Am J Health Syst Pharm 55:1017-24. 1998
    ..No difference in intervention rates was observed for LTC pharmacists, who were already being supplied information by the LTC facilities about patients discharged from the hospital...
  39. ncbi request reprint The effect of alendronate on fracture-related healthcare utilization and costs: the fracture intervention trial
    E A Chrischilles
    Department of Epidemiology, College of Public Health, University of Iowa, Iowa City 52242, USA
    Osteoporos Int 12:654-60. 2001
    ..114). Alendronate thus not only reduces the incidence of clinical fractures and associated morbidity, but reduces the proportion of patients utilizing the associated healthcare resources...
  40. pmc Effect of dialysis center profit-status on patient survival: a comparison of risk-adjustment and instrumental variable approaches
    John M Brooks
    College of Pharmacy, University of Iowa, Program in Pharmaceutical Socioeconomics, Iowa City, IA 52242, USA
    Health Serv Res 41:2267-89. 2006
    ..To compare the estimated effects of dialysis center profit status on patient survival using alternative estimation strategies with retrospective data...
  41. ncbi request reprint Hospital volume-outcome relationships among medical admissions to ICUs
    Lakshmi Durairaj
    Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, USA
    Chest 128:1682-9. 2005
    ..Positive relationships between hospital volume and outcomes have been demonstrated for several surgeries and medical conditions. However, little is known about the volume-outcome relationship in patients admitted to medical ICUs...
  42. doi request reprint Estimating the effect of treatment rate changes when treatment benefits are heterogeneous: antibiotics and otitis media
    Tae Ryong Park
    Health Research Consultant, Health Dialog Analytic Solutions, Portland, ME, USA
    Value Health 11:304-14. 2008
    ..Contrast methods to assess the health effects of a treatment rate change when treatment benefits are heterogeneous across patients. Antibiotic prescribing for children with otitis media (OM) in Iowa Medicaid is the empirical example...
  43. ncbi request reprint The effect of physician characteristics and their practice environment on surgical referral patterns for early-stage breast cancer in Iowa
    Jessica A Davila
    Department of Medicine, Baylor College of Medicine, Houston, TX, USA
    Am J Med Qual 19:266-73. 2004
    ..Promoting interaction among physicians, particularly among those with different specialties, may increase the diffusion of new behaviors into clinical practice...
  44. pmc Hip fracture risk among community-dwelling elderly people in the United States: a prospective study of physical, cognitive, and socioeconomic indicators
    Robin Taylor Wilson
    Division of Epidemiology, Department of Health Evaluation Sciences, Pennsylvania State College of Medicine, and the Penn State Cancer Institute, Hershey, PA 17033 0855, USA
    Am J Public Health 96:1210-8. 2006
    ..We determined risks of short-term (2-year) hip fracture in a nationally representative, prospective cohort of community-dwelling elderly people 70 years or older...
  45. ncbi request reprint Development of a computer algorithm for defining an active drug list using an automated pharmacy database
    Brian C Lund
    Laureate Psychiatric Research Center, Laureate Psychiatric Clinics and Hospital, 6655 South Yale Avenue, Tulsa, OK 74136, USA
    J Clin Epidemiol 56:802-6. 2003
    ..Such determinations often require the creation of a drug regimen at a particular point in time. The objective of this study was to develop a computer algorithm for defining a cross-sectional active drug list...

Research Grants6

  1. Pharmaceutical Case Management and Living Well with a Disability
    Elizabeth Chrischilles; Fiscal Year: 2007
    ..Prescription dispensing records and medical records will be the data source for rating medication use quality using standardized guidelines. ..
  2. Personal Health Records and Elder Medication Use Quality
    Elizabeth Chrischilles; Fiscal Year: 2007
    ..Thus, in a human-computer interaction laboratory, we will investigate the usability of the trial PHR system against alternative prototypes developed through participatory design with older adults of varying ability levels. ..