Research Topics
| Mary Margaret ChrenSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Publications
The contribution of health services research to improved dermatologic careMary Margaret Chren
Department of Dermatology, University of California, San Francisco, San Francisco, California 94143 0808, USA
J Invest Dermatol 132:1003-7. 2012..The paper also addresses some of the political and systematic challenges for health services research overall, and for individual investigators and program leaders...- The Skindex instruments to measure the effects of skin disease on quality of lifeMary Margaret Chren
Department of Dermatology, University of California at San Francisco, San Francisco, CA 94143 0808, USA
Dermatol Clin 30:231-6, xiii. 2012..Studies of quality of life in patients with nonmelanoma skin cancer are described to illustrate the use of Skindex to understand quality of life and to compare effectiveness of different treatments for this highly prevalent condition... - Recurrence after treatment of nonmelanoma skin cancer: a prospective cohort studyMary Margaret Chren
Health Services Research and Development Service, Department of Veterans Affairs, San Francisco VA Medical Center 151R, 4150 Clement St, San Francisco, CA 94121, USA
Arch Dermatol 147:540-6. 2011..To determine long-term tumor recurrence rates after treatment of primary nonmelanoma skin cancer (NMSC). Data are currently insufficient to permit evidence-based choices among treatments for NMSC... 
Quality-of-life outcomes of treatments for cutaneous basal cell carcinoma and squamous cell carcinomaMary Margaret Chren
Dermatology Service, San Francisco Veterans Affairs Medical Center and the Department of Veterans Affairs, San Francisco, California 94121, USA
J Invest Dermatol 127:1351-7. 2007..2 (7.4, 12.9) after Mohs surgery, and 3.4 (-0.9, 7.6) after ED&C. We conclude that, for NMSC, quality-of-life outcomes were similar after excision and Mohs surgery, and both therapies had better outcomes than ED&C...- Interpretation of quality-of-life scoresMary Margaret Chren
Department of Dermatology, University of California, San Francisco, San Francisco, California, USA
J Invest Dermatol 130:1207-9. 2010..The cutoff scores identify patients whose skin diseases severely affect their quality of life... - Predictors of skin-related quality of life after treatment of cutaneous basal cell carcinoma and squamous cell carcinomaTina Chen
School of Medicine, University of California at San Francisco, San Francisco, USA
Arch Dermatol 143:1386-92. 2007..To identify predictors of skin-related quality of life (QOL) after treatment of nonmelanoma skin cancer (NMSC)... - Variation in care for nonmelanoma skin cancer in a private practice and a veterans affairs clinicMary Margaret Chren
Dermatology Service, Research Enhancement Award Program of the Health Services Research and Development Service, Department of Veterans Affairs, San Francisco Veterans Affairs Medical Center, San Francisco, California 94121, USA
Med Care 42:1019-26. 2004..Clinical variables that may affect treatment choices can be identified, but little is known about how clinicians choose among therapies... - Narrative review: the promotion of gabapentin: an analysis of internal industry documentsMichael A Steinman
San Francisco Veterans Affairs Medical Center and University of California, San Francisco, San Francisco, California 94143, USA
Ann Intern Med 145:284-93. 2006..Such documents have become available through litigation concerning the promotion of gabapentin (Neurontin, Pfizer, Inc., New York, New York) for off-label uses... - Cognitive screening predicts magnitude of functional recovery from admission to 3 months after discharge in hospitalized eldersLaura P Sands
UCSF Mt Zion Center on Aging and Department of Medicine, University of California, San Francisco, USA
J Gerontol A Biol Sci Med Sci 58:37-45. 2003..We sought to determine whether performance on a cognitive screen at the time of hospital admission predicted the magnitude of functional recovery after hospitalization... - Renal insufficiency and use of revascularization among a national cohort of men with advanced lower extremity peripheral arterial diseaseANN M O'HARE
Department of Medicine, VA Medical Center, San Francisco, San Francisco, CA 94121, USA
Clin J Am Soc Nephrol 1:297-304. 2006..However, among patients with renal insufficiency, mortality is lowest for patients who receive a revascularization. Further studies are needed to determine the optimal care for this high-risk patient group... - Patient satisfaction after treatment of nonmelanoma skin cancerMaryam M Asgari
Division of Research, Kaiser Permanente Northern California, Oakland, California, USA
Dermatol Surg 35:1041-9. 2009..Patient satisfaction is an important aspect of patient-centered care but has not been systematically studied after treatment of nonmelanoma skin cancer (NMSC), the most prevalent cancer... - Variation in care for recurrent nonmelanoma skin cancer in a university-based practice and a veterans affairs clinicF Landon Clark
Department of Dermatology, Stanford University MedicalCenter, Stanford, California, USA
Arch Dermatol 144:1148-52. 2008..To learn if treatment of recurrent nonmelanoma skin cancer (NMSC) varied in different practice settings... 
A clinical index to stratify hospitalized older adults according to risk for new-onset disabilityKala M Mehta
Division of Geriatrics, University of California at San Francisco, San Francisco, CA 94121, USA
J Am Geriatr Soc 59:1206-16. 2011..Thus, this study's objective was to develop and validate a clinical index to determine, at admission, risk for new-onset disability among older, hospitalized adults at discharge...- Tumor recurrence 5 years after treatment of cutaneous Basal cell carcinoma and squamous cell carcinomaMary Margaret Chren
1 Department of Dermatology, University of California at San Francisco, San Francisco, California, USA 2 San Francisco Veterans Affairs Medical Center, San Francisco, California, USA
J Invest Dermatol 133:1188-96. 2013..These data indicate that common treatments for NMSCs were at least 95% effective, and further studies are needed to guide therapeutic choices for different clinical subgroups... - Association of prediagnostic serum vitamin D levels with the development of basal cell carcinomaMaryam M Asgari
Division of Research, Kaiser Permanente Northern California, Oakland, California, USA
J Invest Dermatol 130:1438-43. 2010..11). Our findings suggest that higher prediagnostic serum 25(OH)D levels may be associated with increased risk of subsequent BCC. Further studies to evaluate the effect of sun exposure on BCC and serum 25(OH)D levels may be warranted... - Skin-related quality of life in HIV-infected patients on highly active antiretroviral therapyParadi Mirmirani
Department of Dermatology, University of California, San Francisco, California 94143 0316, USA
J Cutan Med Surg 6:10-5. 2002..The overall health status and survival of HIV-infected patients has changed with the advent of highly active antiretroviral therapy (HAART). With this improved survival, there is a greater urgency to study quality-of-life issues... - Adaptation of a Runyankore version of Skindex-16 for oral administration in Mbarara, UgandaSer Ling Chua
Department of Dermatology, University of California, San Francisco, CA, USA
Int J Dermatol 50:1249-54. 2011..Little is known about the feasibility of using adaptations of validated instruments in situations where literacy rates are low... - Characteristics and impact of drug detailing for gabapentinMichael A Steinman
Affairs Medical Center, San Francisco, California, United States of America
PLoS Med 4:e134. 2007..In this study, we evaluated the content and impact of detail visits for gabapentin by analyzing market research forms completed by physicians after receiving a detail visit for this drug... - Supplement use and risk of cutaneous squamous cell carcinomaMaryam M Asgari
Division of Research, Kaiser Permanente Northern California, Oakland, California 94612, USA
J Am Acad Dermatol 65:1145-51. 2011..Laboratory and epidemiologic studies suggest that certain dietary supplements may alter risk of cutaneous squamous cell carcinoma (SCC)... - Impact of renal insufficiency on mortality in advanced lower extremity peripheral arterial diseaseANN M O'HARE
Division of Nephrology, Box 111J, Nephrology, VA Medical Center San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
J Am Soc Nephrol 16:514-9. 2005..Death rates were particularly high among those with a GFR <30 ml/min per 1.73 m(2). This finding may be partly explained by their more frequent presentation with ischemic ulceration or gangrene rather than rest pain... - Sun protective behaviors and vitamin D levels in the US population: NHANES 2003-2006Eleni Linos
Department of Dermatology, Stanford University School of Medicine, Pavilion B 2nd Floor, 450 Broadway St, Redwood City, CA 94063, USA
Cancer Causes Control 23:133-40. 2012..Our aim was to investigate the relationship between different types of sun protective behaviors and serum 25(OH)D levels in the general US population... - A pilot quality-of-life instrument for acne rosaceaKimberly Nicholson
Department of Dermatology, Emory University School of Medicine, Atlanta, GA 30322, USA
J Am Acad Dermatol 57:213-21. 2007..No rosacea-specific quality-of-life (QOL) instrument exists... - What's in a name? Use of brand versus generic drug names in United States outpatient practiceMichael A Steinman
Division of Geriatrics, San Francisco VA Medical Center and the University of California, San Francisco, CA 94121, USA
J Gen Intern Med 22:645-8. 2007..The use of brand rather than generic names for medications can increase health care costs. However, little is known at a national level about how often physicians refer to drugs using their brand or generic names... - Effects of vulvodynia on quality of lifeMaya Ponte
School of Medicine, University of California San Francisco, San Francisco, California, USA
J Am Acad Dermatol 60:70-6. 2009..The experiences of women with vulvodynia are poorly understood... - Fitzpatrick skin phototype is an independent predictor of squamous cell carcinoma risk after solid organ transplantationRavinder Gogia
Department of Dermatology, University of California at San Francisco, San Francisco, California 94115, USA
J Am Acad Dermatol 68:585-91. 2013..In predominantly white cohorts, Fitzpatrick skin type (FST) has been reported to be a risk factor for developing posttransplantation skin cancers... - Variability in nomenclature used for nevi with architectural disorder and cytologic atypia (microscopically dysplastic nevi) by dermatologists and dermatopathologistsMichael Shapiro
Department of Dermatology, University of Pennsylvania School of Medicine, 3600 Spruce Street, Philadelphia, PA 19104, USA
J Cutan Pathol 31:523-30. 2004..CONCLUSIONS: Despite attempts to unify nomenclature for microscopically dysplastic nevi through the NIH Consensus Conference, wide variation in terminology persists... - Measurement of vital signs for skin diseasesMary-Margaret Chren
Department of Dermatology, University of California at San Francisco, San Francisco, California, USA
J Invest Dermatol 125:viii-ix. 2005 - Determining the value of surgical therapies for basal cell carcinomaMary-Margaret Chren
Arch Dermatol 142:231-2. 2006 - Conceptual issues in measuring the burden of skin diseasesMary-Margaret Chren
J Investig Dermatol Symp Proc 9:97-100. 2004 - Development of the Childhood Atopic Dermatitis Impact Scale: initial validation of a quality-of-life measure for young children with atopic dermatitis and their familiesSarah L Chamlin
Division of Pediatric Dermatology, Children s Memorial Hospital, Chicago, Illinois, USA
J Invest Dermatol 125:1106-11. 2005..Seventeen items were eliminated, yielding a 45-item refined version of CADIS (score 0-180) with evidence of content and construct validity and suggested use in clinical research... - Scalpdex: a quality-of-life instrument for scalp dermatitisSuephy C Chen
Department of Dermatology and Emory Center for Outcomes Research, Atlanta, GA 30033, USA
Arch Dermatol 138:803-7. 2002..To develop a scalp dermatitis-specific quality-of-life instrument... - The Japanese version of Skindex-16: a brief quality-of-life measure for patients with skin diseasesYuko Higaki
Department of Dermatology, Tokyo Women's Medical University, Tokyo, Japan
J Dermatol 29:693-8. 2002..In conclusion, we have developed a semantically equivalent translation of Skindex-16 into Japanese. It is a reliable and valid measure of the effects of skin disease on the quality of life in Japanese patients... - Association between poorer quality of life and psychiatric morbidity in patients with different dermatological conditionsFrancesca Sampogna
Dermatological Institute IDI-IRCCS, Rome, Italy
Psychosom Med 66:620-4. 2004..Although the cross-sectional nature of our study does not allow identification of the direction of this association, care for the psychological condition of patients might have an impact on their quality of life... - Effects of atopic dermatitis on young American children and their familiesSarah L Chamlin
Division of Pediatric Dermatology, Children s Memorial Hospital, Chicago, Illinois, USA
Pediatrics 114:607-11. 2004..This study was conducted to document these effects of atopic dermatitis on young children and their families... - Nonsteroidal anti-inflammatory drug use in the prevention and treatment of squamous cell carcinomaMaryam Asgari
Division of Dermatology, University of Washington Medical Center, Seattle, Washington 98195, USA
Dermatol Surg 30:1335-42. 2004..Nonsteroidal anti-inflammatory drugs are widely reported to inhibit carcinogenesis... - The price of pruritus: sleep disturbance and cosleeping in atopic dermatitisSarah L Chamlin
Division of Pediatric Dermatology at Children s Memorial Hospital, Chicago, IL, USA
Arch Pediatr Adolesc Med 159:745-50. 2005..Sleep characteristics in young children with atopic dermatitis and their families have not been thoroughly investigated... - Evaluating clinical rating scales for evidence-based dermatology: some basic conceptsMadhulika A Gupta
Department of Psychiatry, University of Western Ontario, London, ON, Canada
Dermatol Clin 23:703-6. 2005..Also discussed is the impact of these parameters on increasing the statistical power of a clinical trial... - Testing and reducing skindex-29 using Rasch analysis: Skindex-17Tamar E C Nijsten
Department of Dermatology, Erasmus Medical Center, Rotterdam, The Netherlands
J Invest Dermatol 126:1244-50. 2006..The Skindex-17 is a Rasch reduced version of Skindex-29, with two independent scores that can be used in the measurement of HRQOL in dermatological patients... - Turkish version of Skindex-29Ayse Esra Koku Aksu
Department of Dermatology, Osmangazi University Medical School, Eskisehir, Turkey
Int J Dermatol 46:350-5. 2007..Most of the existing dermatology-specific measures were developed for the English language, and these measures should be adapted for use in other cultures... - Childhood Atopic Dermatitis Impact Scale: reliability, discriminative and concurrent validity, and responsivenessSarah L Chamlin
Division of Pediatric Dermatology, Children s Memorial Hospital, Chicago, IL 60614, and Center on Outcomes Research and Education, Evanston Northwestern Healthcare and Northwestern Feinberg School of Medicine, USA
Arch Dermatol 143:768-72. 2007..To evaluate the test-retest reliability, discriminative and concurrent validity, and responsiveness of the Childhood Atopic Dermatitis Impact Scale (CADIS), a quality-of-life scale with 5 domains... - Doctor's orders: rethinking compliance in dermatologyMary-Margaret Chren
Arch Dermatol 138:393-4. 2002
Research Grants
- COMPREHENSIVE OUTCOME OF NONMELANOMA SKIN CANCERMary Margaret Chren; Fiscal Year: 2005..abstract_text> ..
- Patient-Oriented Research in Skin DiseasesMary Margaret Chren; Fiscal Year: 2007..Chren to broaden the scope of her on-going research as well as formalize an explicit mentoring arrangement for developing new patient-oriented investigators in skin diseases. ..
- Long-Term Outcomes of Nonmelanoma Skin CancerMary Margaret Chren; Fiscal Year: 2009..The results will also provide a basis for planning controlled trials of different treatments of NMSC, to guide decisions about the use of resources for this common tumor. ..
- Long-Term Outcomes of Nonmelanoma Skin CancerMary Margaret Chren; Fiscal Year: 2009..The results will also provide a basis for planning controlled trials of different treatments of NMSC, to guide decisions about the use of resources for this common tumor. ..