Parimal Chowdhury

Summary

Affiliation: University of Arkansas for Medical Sciences
Country: USA

Publications

  1. pmc Effect of nicotine on exocytotic pancreatic secretory response: role of calcium signaling
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, College of Medicine, 4301 W Markham Street, Little Rock, 72205, Arkansas
    Tob Induc Dis 11:1. 2013
  2. ncbi request reprint Effects of aminoguanidine on tissue oxidative stress induced by hindlimb unloading in rats
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Ann Clin Lab Sci 39:64-70. 2009
  3. pmc A report of the Sixth Annual Meeting of the International Society for the Prevention of Tobacco Induced Diseases (ISPTID)
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 4301 W Markham Street, Little Rock, AR 72205, USA
    Tob Induc Dis 4:11. 2008
  4. pmc Mitogenic and functional responses by nicotine and hydrogen peroxide in AR42J cells: a comparative study
    Azida Walker
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Tob Induc Dis 4:5. 2008
  5. doi request reprint A cell-based approach to study changes in the pancreas following nicotine exposure in an animal model of injury
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Langenbecks Arch Surg 393:547-55. 2008
  6. ncbi request reprint L-carnitine influence on oxidative stress induced by hind limb unloading in adult rats
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR 72205, USA
    Aviat Space Environ Med 78:554-6. 2007
  7. ncbi request reprint Nicotine-induced proliferation of isolated rat pancreatic acinar cells: effect on cell signalling and function
    P Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, College of Medicine, Little Rock, AR 72205, USA
    Cell Prolif 40:125-41. 2007
  8. ncbi request reprint Nicotine as a mitogenic stimulus for pancreatic acinar cell proliferation
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 4301 W Markham Street, Little Rock, Arkansas 72205, United States
    World J Gastroenterol 12:7428-32. 2006
  9. ncbi request reprint Pathophysiology of alcoholic pancreatitis: an overview
    Parimal Chowdhury
    Department of Physiology and Biophysics, College of Medicine, University of Arkansas for Medical Sciences, 4301 W Markham Street, Little Rock, Arkansas 72205, United States
    World J Gastroenterol 12:7421-7. 2006
  10. ncbi request reprint Activation of p-ERK1/2 by nicotine in pancreatic tumor cell line AR42J: effects on proliferation and secretion
    Chhanda Bose
    Donald W Reynolds Department of Geriatrics, University of Arkansas for Medical Sciences, College of Medicine, Little Rock, Arkansas 72205, USA
    Am J Physiol Gastrointest Liver Physiol 289:G926-34. 2005

Collaborators

Detail Information

Publications25

  1. pmc Effect of nicotine on exocytotic pancreatic secretory response: role of calcium signaling
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, College of Medicine, 4301 W Markham Street, Little Rock, 72205, Arkansas
    Tob Induc Dis 11:1. 2013
    ..abstract:..
  2. ncbi request reprint Effects of aminoguanidine on tissue oxidative stress induced by hindlimb unloading in rats
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Ann Clin Lab Sci 39:64-70. 2009
    ..05). In summary, HLU induced an oxidative response in rats and this response was reduced significantly by ingestion of AG. These results suggest the potential application of AG in the diet of astronauts living in a stressful environment...
  3. pmc A report of the Sixth Annual Meeting of the International Society for the Prevention of Tobacco Induced Diseases (ISPTID)
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 4301 W Markham Street, Little Rock, AR 72205, USA
    Tob Induc Dis 4:11. 2008
    ..The meeting set the tone for next the Annual meeting in Kyoto, Japan for the year 2008 with the theme "Tobacco free future"...
  4. pmc Mitogenic and functional responses by nicotine and hydrogen peroxide in AR42J cells: a comparative study
    Azida Walker
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR, USA
    Tob Induc Dis 4:5. 2008
    ..The data suggests that nicotine-induced mitogenic response in AR42J cells closely identifies the response induced by an oxidative biomarker...
  5. doi request reprint A cell-based approach to study changes in the pancreas following nicotine exposure in an animal model of injury
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Langenbecks Arch Surg 393:547-55. 2008
    ..Cigarette smoking is a recognized risk factor for the induction of pancreatic diseases and is suspected to play a major role in the development of pancreatic cancer in smokers...
  6. ncbi request reprint L-carnitine influence on oxidative stress induced by hind limb unloading in adult rats
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 4301 W Markham St, Little Rock, AR 72205, USA
    Aviat Space Environ Med 78:554-6. 2007
    ..L-carnitine, a well-known enhancer of activities of the mitochondrial antioxidant system, was used to confirm the HLU-induced oxidative response...
  7. ncbi request reprint Nicotine-induced proliferation of isolated rat pancreatic acinar cells: effect on cell signalling and function
    P Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, College of Medicine, Little Rock, AR 72205, USA
    Cell Prolif 40:125-41. 2007
    ....
  8. ncbi request reprint Nicotine as a mitogenic stimulus for pancreatic acinar cell proliferation
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 4301 W Markham Street, Little Rock, Arkansas 72205, United States
    World J Gastroenterol 12:7428-32. 2006
    ..In addition, the editorial reviews very recent literature of the contribution of MAPK signaling in cell lines associated with human diseases. A prospective cellular model of nicotine induced activation of MAPK cascade is presented...
  9. ncbi request reprint Pathophysiology of alcoholic pancreatitis: an overview
    Parimal Chowdhury
    Department of Physiology and Biophysics, College of Medicine, University of Arkansas for Medical Sciences, 4301 W Markham Street, Little Rock, Arkansas 72205, United States
    World J Gastroenterol 12:7421-7. 2006
    ..Reports describing prospective mechanisms of action of alcohol activating the signal transduction pathways, induction of oxidative stress parameters through the development of animal models are being presented...
  10. ncbi request reprint Activation of p-ERK1/2 by nicotine in pancreatic tumor cell line AR42J: effects on proliferation and secretion
    Chhanda Bose
    Donald W Reynolds Department of Geriatrics, University of Arkansas for Medical Sciences, College of Medicine, Little Rock, Arkansas 72205, USA
    Am J Physiol Gastrointest Liver Physiol 289:G926-34. 2005
    ..We conclude that nicotine treatment induced activation of ERK1/2 and increased the proliferation of AR42J cells. The data further indicate that MAPK signaling by nicotine is independent of the secretory response...
  11. ncbi request reprint Nanocluster model of photothermal assay: application for high-sensitive monitoring of nicotine-induced changes in metabolism, apoptosis, and necrosis at a cellular level
    Vladimir P Zharov
    University of Arkansas for Medical Sciences, Philips Classic Laser Laboratories, 4301 West Markham Street, Number 543, Little Rock, Arkansas 72205 7199, USA
    J Biomed Opt 10:44011. 2005
    ..Comparison of PT responses of pancreatic tumor cells AR42J with isolated primary pancreatic acinar cells and HepG2 cells shows a universal nature of PT assay...
  12. ncbi request reprint Brief communication: Effects of soy-protein diet on elevated brain lipid peroxide levels induced by simulated weightlessness
    Michael E Soulsby
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Ann Clin Lab Sci 34:103-6. 2004
    ..These observations imply that the soy-protein diet has a protective antioxidant effect during both the basal condition and the stressful condition...
  13. ncbi request reprint Attenuation of tissue oxidative stress by dietary restriction in rats on simulated microgravity
    John Jayroe
    University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Ann Clin Lab Sci 42:140-4. 2012
    ..The goal of this study is to determine the consequences of a twenty percent caloric restriction on the increased oxidative stress documented in tissues from rats exposed to simulated microgravity...
  14. ncbi request reprint Self-assembly and binding of a sorting nexin to sorting endosomes
    R C Kurten
    Department of Physiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205 0750, USA
    J Cell Sci 114:1743-56. 2001
    ..http://www.biologists.com/JCS/movies/jcs2058.html..
  15. pmc An exploratory study on the development of an animal model of acute pancreatitis following nicotine exposure
    P Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences
    Tob Induc Dis 1:213-7. 2003
    ..It is proposed that rats could be considered as a potential animal model to study the pathogenesis of pancreatitis...
  16. ncbi request reprint Distribution of 3H-nicotine in rat tissues under the influence of simulated microgravity
    P Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock 72205, USA Chowdhury
    Biomed Environ Sci 12:103-9. 1999
    ..The lack of differences in nicotine retention in liver and kidney between control and suspended groups may implicate a normal metabolic function of these organs even under simulated weightlessness...
  17. ncbi request reprint Response of rat exocrine pancreas to high-fat and high-carbohydrate diets
    P Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock 72205, USA
    Proc Soc Exp Biol Med 223:310-5. 2000
    ....
  18. ncbi request reprint Smoking and pancreatic disorders
    P Chowdhury
    University of Arkansas for Medical Sciences, Little Rock 72205, USA
    Eur J Gastroenterol Hepatol 12:869-77. 2000
    ..A hypothetical pancreatic acinar cell model showing multiple signal transduction pathways is presented relating to possible mechanisms of action of nicotine on the pathophysiology of the pancreas...
  19. ncbi request reprint Effect of food restriction on plasma cholecystokinin levels and exocrine pancreatic function in rats
    P Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock 72205, USA
    Ann Clin Lab Sci 31:376-82. 2001
    ..The data suggest that CCK plays an important physiological role in the adaptation to eating less food, and thereby to the lowering of body weight in rats and, possibly, in other animals...
  20. ncbi request reprint Pressure hyperalgesia in hind limb suspended rats
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Aviat Space Environ Med 82:988-91. 2011
    ..The current study was designed to determine whether or not simulated microgravity induced by hind limb suspension (HLS) in rats lead to insulinopenia and pressure hyperalgesia...
  21. ncbi request reprint Lipid peroxidation in rat brain is increased by simulated weightlessness and decreased by a soy-protein diet
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock 72205, USA
    Ann Clin Lab Sci 32:188-92. 2002
    ....
  22. ncbi request reprint The genetics of nicotine dependence: relationship to pancreatic cancer
    Stewart L MacLeod
    Department of Pediatrics, University of Arkansas for Medical Sciences, College of Medicine, Arkansas Center for Birth Defects Research and Prevention, 1120 Marshall St Mail Slot 512 40, Little Rock, AR 72202, United States
    World J Gastroenterol 12:7433-9. 2006
    ....
  23. ncbi request reprint Pathophysiological effects of nicotine on the pancreas: an update
    Parimal Chowdhury
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR 72205, USA
    Exp Biol Med (Maywood) 227:445-54. 2002
    ..A possible pathogenetic mechanism of nicotine in the pancreas activating multiple signal transduction pathways is schematically summarized in Figure 1...
  24. ncbi request reprint Photothermal detection of nicotine-induced apoptotic effects in pancreatic cancer cells
    Valentin Galitovsky
    Philips Classic Laser Biomedical Laboratory, University of Arkansas for Medical Sciences UAMS, 4301 West Markham St, Slot 543, Little Rock, AR 72205, USA
    Life Sci 75:2677-87. 2004
    ..Thus, the PT assay demonstrated the capability for high-sensitivity detection of nicotine's impact, which may be related to a change in cell metabolism, apoptosis, or necrosis, depending on nicotine concentration...
  25. ncbi request reprint Neural mechanisms of pancreatic polypeptide release in conscious dogs
    R Hosotani
    Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock 72205
    Am J Physiol 257:G134-7. 1989
    ..This study suggests that CCK might be involved in the neural control of PP release as a neurotransmitter but probably not as a final activator of PP cells in dogs...

Research Grants1

  1. Sixth Annual Meeting of the Internatioanl Society for the Prevention of Tobacco I
    Parimal Chowdhury; Fiscal Year: 2007
    ..Thus, this meeting will be a resource to decrease the huge sociological and economic burden the world faces regarding addiction to tobacco. ..