Research Topics
Species | H H Sherry ChowSummaryAffiliation: University of Arizona Country: USA Publications
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Detail Information
Publications
Gender difference in systemic oxidative stress and antioxidant capacity in current and former heavy smokersIman A Hakim
The University of Arizona Cancer Center, Tucson, AZ, USA
Cancer Epidemiol Biomarkers Prev 21:2193-200. 2012....
Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon EH H Chow
Arizona Cancer Center, The University of Arizona, Tucson 85724, USA
Cancer Epidemiol Biomarkers Prev 10:53-8. 2001..The systemic availability of EGCG increased at higher doses, possibly due to saturable presystemic elimination of orally administered green tea polyphenols...- Effects of repeated green tea catechin administration on human cytochrome P450 activityH H Sherry Chow
Arizona Cancer Center, The University of Arizona, Tucson, AZ 85724, USA
Cancer Epidemiol Biomarkers Prev 15:2473-6. 2006..We conducted this clinical study to determine the effect of repeated green tea catechin administration on human cytochrome P450 (CYP) enzyme activities... 
Resveratrol modulates drug- and carcinogen-metabolizing enzymes in a healthy volunteer studyH H Sherry Chow
Arizona Cancer Center, The University of Arizona, Tucson, AZ 85724, USA
Cancer Prev Res (Phila) 3:1168-75. 2010..Further clinical development of resveratrol for cancer prevention should consider evaluation of lower doses of resveratrol to minimize adverse metabolic drug interactions...- Effects of dosing condition on the oral bioavailability of green tea catechins after single-dose administration of Polyphenon E in healthy individualsH H Sherry Chow
Arizona Cancer Center, The University of Arizona, Tucson, Arizona 85724, USA
Clin Cancer Res 11:4627-33. 2005..Tea catechin concentrations in plasma and urine samples collected after dosing were determined by high-pressure liquid chromatography analysis... - Modulation of human glutathione s-transferases by polyphenon e interventionH H Sherry Chow
Arizona Cancer Center, The University of Arizona, Tucson, AZ 85724, USA
Cancer Epidemiol Biomarkers Prev 16:1662-6. 2007..We conducted this clinical study to determine the effect of repeated green tea polyphenol administration on a major group of detoxification enzymes, glutathione S-transferases (GST)... - Pharmacokinetic and chemoprevention studies on tea in humansH H Sherry Chow
Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, United States
Pharmacol Res 64:105-12. 2011..Emerging data from multiple ongoing intervention trials will further contribute to defining the cancer preventive activity of green tea or green tea catechins... - Pharmacokinetics of perillic acid in humans after a single dose administration of a citrus preparation rich in d-limonene contentH H Sherry Chow
Arizona Cancer Center, The University of Arizona, Tucson, Arizona 85724, USA
Cancer Epidemiol Biomarkers Prev 11:1472-6. 2002..07 to 32.59 (micro M) x h. Our study illustrates that the major metabolite of d-limonene is bioavailable after oral consumption of a citrus preparation rich in d-limonene content... - Direct nose-brain transport of benzoylecgonine following intranasal administration in ratsH H Chow
Arizona Cancer Center and Department of Pharmacy Practice and Science, The University of Arizona, Tucson, Arizona 85724, USA
J Pharm Sci 90:1729-35. 2001..Factors contributing to the observed differences in the nose-brain transport of cocaine and benzoylecgonine are discussed... - Effect of a 4-month tea intervention on oxidative DNA damage among heavy smokers: role of glutathione S-transferase genotypesIman A Hakim
Mel and Enid Zuckerman Arizona College of Public Health, University of Arizona and Arizona Cancer Center, Tucson, Arizona 85724, USA
Cancer Epidemiol Biomarkers Prev 13:242-9. 2004..This finding also suggests that green tea intervention may be effective in the subgroup of smokers who are GSTM1 and/or GSTT1 positive... - Effect of increased tea consumption on oxidative DNA damage among smokers: a randomized controlled studyIman A Hakim
Mel and Enid Zuckerman Arizona College of Public Health, University of Arizona, Tucson, AZ 85724, USA
J Nutr 133:3303S-3309S. 2003..These data suggest that regular green tea drinking might protect smokers from oxidative damages and could reduce cancer risk or other diseases caused by free radicals associated with smoking... - Effects of a high-selenium yeast supplement on celecoxib plasma levels: a randomized phase II trialDenise H Frank
Arizona Cancer Center, and Section of Hematology and Oncology, Department of Medicine, College of Medicine, University of Arizona, Tucson, Arizona 85724, USA
Cancer Epidemiol Biomarkers Prev 13:299-303. 2004..In future Phase III chemoprevention trials of celecoxib, weight gain should be carefully monitored, and participants should be made aware of this potential side effect before study entry... - Adipose tissue accumulation of d-limonene with the consumption of a lemonade preparation rich in d-limonene contentJessica A Miller
Arizona Cancer Center, The University of Arizona, Tucson, AZ 85724, USA
Nutr Cancer 62:783-8. 2010..009). Our results demonstrate accumulation of d-limonene in adipose tissue after oral dosing and support additional studies of d-limonene for chemoprevention in tissues such as the breast that are comprised of a significant fat fraction... - Determination of celecoxib in human plasma using solid-phase extraction and high-performance liquid chromatographyH H Sherry Chow
Arizona Cancer Center, The University of Arizona, 1515 N Campbell Avenue, Tucson, AZ 85724 5024, USA
J Pharm Biomed Anal 34:167-74. 2004..S.D. for the assay was less than 12 and 5%, respectively. This assay has been applied to the analysis of celecoxib levels in plasma samples collected from healthy participants entered into a Phase II clinical study... - Results of a phase I multiple-dose clinical study of ursodeoxycholic AcidLisa M Hess
Arizona Cancer Center, University of Arizona Health Sciences Center, 1515 North Campbell Avenue, POB 245024, Tucson, AZ 85724 5024, USA
Cancer Epidemiol Biomarkers Prev 13:861-7. 2004.... - Interaction of dacarbazine and imexon, in vitro and in vivo, in human A375 melanoma cellsBetty K Samulitis
College of Medicine, Arizona Cancer Center, University of Arizona, Tucson, AZ 85724 5024, USA
Anticancer Res 31:2781-5. 2011..We evaluated mechanisms of interaction between the alkyating agent dacarbazine (DTIC) and the pro-oxidant, imexon, in the human A375 melanoma cell line... - Sulindac and sulindac metabolites in nipple aspirate fluid and effect on drug targets in a phase I trialPatricia A Thompson
Arizona Cancer Center, University of Arizona, Tucson, 85724 5024, USA
Cancer Prev Res (Phila) 3:101-7. 2010..038). These results are the first to show partitioning of sulindac and metabolites to human breast tissue and the first evidence for a potential dose-dependent effect of sulindac on growth differentiation factor 15 levels in NAF... - Design and baseline characteristics of participants in a phase III randomized trial of celecoxib and selenium for colorectal adenoma preventionPatricia Thompson
University of Arizona Cancer Center, 1515 N Campbell Avenue, Tucson, AZ 85724, USA
Cancer Prev Res (Phila) 5:1381-93. 2012..Intervention effects on adenoma recurrence will be determined, and their modification by genetic background and baseline selenium level. The effect of selenium supplementation on risk for type II diabetes will also be reported... - Phase I trial of intraperitoneal pemetrexed, cisplatin, and paclitaxel in optimally debulked ovarian cancerSetsuko K Chambers
University of Arizona Cancer Center, Tucson, Arizona 85724, USA
Clin Cancer Res 18:2668-78. 2012..This phase I trial evaluated intraperitoneal (i.p.) pemetrexed, cisplatin, and paclitaxel in optimally debulked ovarian cancer... - Randomized, double-blind, placebo-controlled trial of polyphenon E in prostate cancer patients before prostatectomy: evaluation of potential chemopreventive activitiesMike M Nguyen
Division of Urology, College of Medicine, The University of Arizona, Tucson, AZ 85724, USA
Cancer Prev Res (Phila) 5:290-8. 2012.... - Green tea consumption is associated with decreased DNA damage among GSTM1-positive smokers regardless of their hOGG1 genotypeIman A Hakim
Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ 85724, USA
J Nutr 138:1567S-1571S. 2008..Our finding also suggests that green tea intervention might be effective in decreasing DNA damage in the subgroup of smokers who are GSTM1 positive regardless of their hOGG1 genotype... - Phase I trial of imexon in patients with advanced malignancyTomislav Dragovich
College of Medicine, Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA
J Clin Oncol 25:1779-84. 2007..The purpose of this trial was to define the maximum-tolerated dose (MTD), toxicities, pharmacokinetics, and pharmacodynamics of imexon in patients with advanced cancers... - Determination of d-limonene in adipose tissue by gas chromatography-mass spectrometryJessica A Miller
Department of Nutritional Sciences, The University of Arizona, Tucson, AZ 85721, USA
J Chromatogr B Analyt Technol Biomed Life Sci 870:68-73. 2008..7 to 3.8%) and between-day precision (R.S.D. 6.0-10.7%) and accuracy (%difference of 1.8-2.6%) were achieved. The assay was successfully applied to human fat biopsy samples from a d-limonene feeding trial... - Contribution of presystemic hepatic extraction to the low oral bioavailability of green tea catechins in ratsYan Cai
College of Pharmacy, University of Arizona, Tucson, Arizona 85724, USA
Drug Metab Dispos 30:1246-9. 2002.... - Characterization of novel diaryl oxazole-based compounds as potential agents to treat pancreatic cancerArthur Y Shaw
College of Pharmacy, University of Arizona, Tucson, Arizona, USA
J Pharmacol Exp Ther 331:636-47. 2009..5 h, and cytotoxic drug concentrations of >3 muM were achieved in vivo in mice. The diaryl oxazole series of compounds represent a new chemical class of anticancer agents that inhibit several types of cancer-relevant protein kinases... - Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individualsH-H Sherry Chow
Arizona Cancer Center, The University of Arizona, Tucson, Arizona 85724, USA
Clin Cancer Res 9:3312-9. 2003..There is a >60% increase in the systemic availability of free EGCG after chronic green tea polyphenol administration at a high daily bolus dose (800 mg EGCG or Polyphenon E once daily)... - Cellular accumulation of dietary anticarcinogenic isothiocyanates is followed by transporter-mediated export as dithiocarbamatesEileen C Callaway
Arizona Cancer Center, College of Medicine, University of Arizona, Tucson, AZ 85724, USA
Cancer Lett 204:23-31. 2004..These findings are consistent with our previous results regarding cellular export of another anticarcinogenic ITC, sulforaphane, and suggest a common cellular response to ITCs... - Quantification of a cytochrome P450 3A4 substrate, buspirone, in human plasma by liquid chromatography-tandem mass spectrometryWade M Chew
Arizona Cancer Center, The University of Arizona, Tucson, AZ 85724, United States
J Chromatogr B Analyt Technol Biomed Life Sci 844:235-9. 2006..7-11.1%) and accuracy (% difference of 2.2-6.8%) were obtained. The assay has been successfully applied to the analysis of buspirone levels in more than 500 human plasma samples collected from a drug interaction study... - A Phase I pharmacokinetic and pharmacodynamic study of PX-12, a novel inhibitor of thioredoxin-1, in patients with advanced solid tumorsRamesh K Ramanathan
Division of Hematology Oncology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Clin Cancer Res 13:2109-14. 2007..Objectives of this study were to determine safety, tolerability, pharmacodynamics, and pharmacokinetics of PX-12, a small-molecule inhibitor of Trx-1...