Research Topics
| Dean ChouSummaryAffiliation: University of California Country: USA Publications
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Publications
The treatment of lumbar adjacent segment pathology after a previous lumbar surgery: a systematic reviewDean Chou
Department of Neurosurgery, University of California San Francisco, San Francisco, CA 94143, USA
Spine (Phila Pa 1976) 37:S180-8. 2012..Systematic review...
Adjacent-level vertebral body fractures after expandable cage reconstructionDean Chou
Department of Neurological Surgery, University of California San Francisco, California 94143 0112, USA
J Neurosurg Spine 8:584-8. 2008..The authors report 4 cases of adjacent-level vertebral body fractures after placement of expandable cages. This study found that the fracture pattern in the coronal plane was similar in all cases...
Rib-head osteotomies for posterior placement of expandable cages in the treatment of metastatic thoracic spine tumorsDean Chou
Department of Neurosurgery, University of California San Francisco, San Francisco, California 94143 0112, USA
J Clin Neurosci 15:1043-7. 2008..We describe a technical note that may facilitate the placement of an expandable cage in the thoracic spine after posterior transpedicular corpectomies...
Trap-door rib-head osteotomies for posterior placement of expandable cages after transpedicular corpectomy: an alternative to lateral extracavitary and costotransversectomy approachesDean Chou
Department of Neurological Surgery, University of California, San Francisco, California, USA
J Neurosurg Spine 10:40-5. 2009..The authors describe a technique of using a "trap-door" rib-head osteotomy that avoids pleural dissection, yet allows a large expandable cage to be placed from an entirely posterior approach...
Two-level en bloc spondylectomy for osteosarcoma at the cervicothoracic junctionDean Chou
Department of Neurological Surgery, University of California San Francisco, 505 Parnassus Avenue, Box 0112, San Francisco, California 94143 0112, USA
J Clin Neurosci 16:698-700. 2009..We present a 22-year-old female with a two-level vertebral involvement at the cervicothoracic junction who underwent a two-level en bloc spondylectomy for osteosarcoma, and we describe our technique...
Spontaneous regression of a discal cyst. Case reportDean Chou
Department of Neurological Surgery, Division of Neuroradiology, University of California, San Francisco, California 94143 0112, USA
J Neurosurg Spine 6:81-4. 2007..The natural history of this pathological entity is unknown, and to the authors' knowledge this is the first detailed report of the regression of a discal cyst without surgery or aspiration...
Primary dural repair during minimally invasive microdiscectomy using standard operating room instrumentsDean Chou
Department of Neurosurgery, University of California, San Francisco, San Francisco, California 94143 0350, USA
Neurosurgery 64:356-8; discussion 358-9. 2009..One reason for the difficulty in a primary closure is that the small tube limits the use of proper opening and closing of standard dural repair instruments as well as the proper angulation of the instruments...
Parasagittal osteotomy for en bloc resection of multilevel cervical chordomasDean Chou
Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143 0350, USA
J Neurosurg Spine 10:397-403. 2009..The authors report their management of 3 multilevel cervical chordomas and describe their technique of en bloc tumor removal using parasagittal osteotomy...
Degenerative magnetic resonance imaging changes in patients with chronic low back pain: a systematic reviewDean Chou
Department of Neurosurgery, University of California, San Francisco, CA 94143, USA
Spine (Phila Pa 1976) 36:S43-53. 2011..Systematic review...
Transpedicular corpectomy with posterior expandable cage placement for L1 burst fractureDean Chou
Department of Neurological Surgery, University of California San Francisco, San Francisco, California 94143 0350, USA
J Clin Neurosci 16:1069-72. 2009..We describe our surgical procedure in this technical note...
Rib head disarticulation for multilevel transpedicular thoracic corpectomies and expandable cage reconstructionDean Chou
Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143 0112, USA
Neurol India 57:469-74. 2009..This avoids pleural dissection and affords expandable cage placement through a transpedicular approach...
Mini-open transpedicular corpectomies with expandable cage reconstruction. Technical noteDean Chou
Department of Neurosurgery, University of California, San Francisco, California 94143 0112, USA
J Neurosurg Spine 14:71-7. 2011..This is performed using percutaneous pedicle screws, the trap-door rib-head osteotomy, and a single midline fascial exposure. The authors describe this technique with intraoperative photos and a video demonstrating the technique...
Surgical technique of temporary arterial occlusion in the operative management of spinal hemangioblastomasAaron J Clark
Department of Neurological Surgery, University of California, San Francisco, California, USA
World Neurosurg 74:200-5. 2010..Although benign, their highly vascular nature makes resection challenging. A major difficulty involves intraoperative differentiation of vessels supplying the tumor from those supplying the spinal cord...
Anterior thoracolumbar corpectomies: approach morbidity with and without an access surgeonSeunggu J Han
Department of Neurological Surgery, University of California San Francisco, San Francisco, California 94143, USA
Neurosurgery 68:1220-5; discussion 1225-6. 2011..Anterior approaches for thoracolumbar corpectomies can have significant morbidity. Spine surgeons have historically performed their own anterior approaches, but recently access surgeons are being used more frequently...
Pedicle subtraction osteotomies for the correction of post-traumatic thoracolumbar kyphosisDean Chou
Department of Neurological Surgery, University of California San Francisco, 400 Parnassus Ave, Box 0350 San Francisco, California 94143 0350, USA
J Clin Neurosci 17:113-7. 2010..We apply this technique in the setting of post-traumatic kyphosis, and we performed the osteotomies at the level of the compression fracture...
Long-term biomechanical stability and clinical improvement after extended multilevel corpectomy and circumferential reconstruction of the cervical spine using titanium mesh cagesFrank L Acosta
Department of Neurological Surgery, University of California, San Francisco, CA 94143, USA
J Spinal Disord Tech 21:165-74. 2008..Retrospective review of clinical case series...
Surgical management of cervical and lumbosacral radiculopathies: indications and outcomesPhillip B Storm
Department of Neurological Surgery, Johns Hopkins University School of Medicine, 725 North Wolfe Street, 817 Hunterian Boulevard, Baltimore, MD 21205, USA
Phys Med Rehabil Clin N Am 13:735-59. 2002....
Surgical site infection in spinal surgery: description of surgical and patient-based risk factors for postoperative infection using administrative claims dataAmir Abdul-Jabbar
Department of Orthopaedic Surgery, University of California, San Francisco, CA 94143, USA
Spine (Phila Pa 1976) 37:1340-5. 2012..Retrospective analysis...
Free-hand thoracic pedicle screws placed by neurosurgery residents: a CT analysisVincent Y Wang
Department of Neurological Surgery, University of California, 505 Parnassus Ave, Box 0112, San Francisco, CA 94143 0112, USA
Eur Spine J 19:821-7. 2010..There were no re-operations for screw replacement. We concluded that under appropriate supervision, neurosurgery residents can safely place free-hand thoracic pedicle screws with an acceptable breach rate...
Comprehensive management of symptomatic and aggressive vertebral hemangiomasFrank L Acosta
Department of Neurological Surgery, University of California, San Francisco, R505 Parnassus Avenue, Room M 779, San Francisco, CA 94143 0112, USA
Neurosurg Clin N Am 19:17-29. 2008..Vertebroplasty is useful for improving pain symptoms, especially when vertebral body compression fracture has occurred in patients without neurological deficit, but is less effective in providing long-term pain relief...
The use of allograft or autograft and expandable titanium cages for the treatment of vertebral osteomyelitisDaniel C Lu
Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143 0350, USA
Neurosurgery 64:122-9; discussion 129-30. 2009..The results of the surgical treatment of osteomyelitis with expandable titanium cages and either allograft or autograft are presented...
The cervicothoracic junctionVincent Y Wang
Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA
Neurosurg Clin N Am 18:365-71. 2007..It is also a difficult region to access anteriorly because of the vital structures ventral to the CTJ. The development of new surgical techniques and new instrumentation has allowed better access and fixation to the CTJ...
Partial spondylectomy: modification for lateralized malignant spinal column tumors of the cervical or lumbosacral spineJohn H Chi
Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue M779, Box 0112, San Francisco, CA 94143, USA
J Clin Neurosci 15:43-8. 2008..Partial spondylectomy can be an alternative to total en bloc spondylectomy in properly selected patients with lateralized encapsulated malignant spinal tumors and may be performed in the cervical or lumbosacral spinal regions...
The transpedicular approach compared with the anterior approach: an analysis of 80 thoracolumbar corpectomiesDaniel C Lu
Department of Neurosurgery, University of California, San Francisco, San Francisco, California 94143 0112, USA
J Neurosurg Spine 12:583-91. 2010..The authors conducted a study to analyze whether there was a difference in outcomes by comparing transpedicular corpectomies to standard anterior thoracolumbar corpectomies...
Multilevel anterior cervical discectomy and fusion with and without rhBMP-2: a comparison of dysphagia rates and outcomes in 150 patientsDaniel C Lu
Department of Neurosurgery, University of California, Los Angeles, CA 90095, USA
J Neurosurg Spine 18:43-9. 2013..The authors report one of the first such comparisons between these 2 patient cohorts...
En bloc resection of primary tumors of the cervical spine: report of two cases and systematic review of the literatureJordan M Cloyd
Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, M779, Box 0112, San Francisco, CA 94143, USA
Spine J 9:928-35. 2009..Survival data and rates of recurrence after en bloc resection for cervical spinal tumors are limited to single case reports and small case series, making the true risk of recurrence after this procedure unknown...
Diagnosis and management of adult pyogenic osteomyelitis of the cervical spineFrank L Acosta
Department of Neurological Surgery, University of California, San Francisco, California 94143, USA
Neurosurg Focus 17:E2. 2004....
Treatment of Enneking stage 3 aggressive vertebral hemangiomas with intralesional spondylectomy: report of 10 cases and review of the literatureFrank L Acosta
Department of Neurological Surgery, Cedars Sinai Medical Center, Los Angeles, CA, USA
J Spinal Disord Tech 24:268-75. 2011..A retrospective review of consecutive series of Enneking stage 3 vertebral hemangiomas surgically treated at a major tertiary spine tumor center...
C1 lateral mass fixation: a comparison of constructsPraveen V Mummaneni
Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143 0112, USA
Neurosurgery 66:153-60. 2010..We compare the results of 3 different constructs incorporating C1 lateral mass screws: occipitocervical (OC) constructs, C1-C2 constructs, and C1 to mid/low cervical constructs...
Complications and perioperative factors associated with learning the technique of minimally invasive transforaminal lumbar interbody fusion (TLIF)Darryl Lau
Department of Neurosurgery, University of California San Francisco, 505 Parnassus Avenue, Box 0112, San Francisco, CA 94143 0112, USA
J Clin Neurosci 18:624-7. 2011..However, the MIS TLIF group tended to have a higher rate of complications, which might have been associated with the learning curve. Both groups had a minimum of 1-year follow-up...
Esophageal erosion 9 years after anterior cervical plate implantationDaniel C Lu
Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143 0112, USA
Surg Neurol 69:310-2; discussion 312-3. 2008..Long-term complications are not often described. A review of literature revealed 5 years as the longest complication interval. We present a case of esophageal erosion 9 years after initial surgery that was successfully treated...
A biomechanical comparison of three anterior thoracolumbar implants after corpectomy: are two screws better than one?Dean Chou
Department of Neurosurgery, University of California San Francisco, USA
J Neurosurg Spine 4:213-8. 2006..A secondary goal was to investigate differences in the ability of the systems to stabilize the spine after a one- or two-level corpectomy...
A comparison of mini-open and open approaches for resection of thoracolumbar intradural spinal tumorsDaniel C Lu
Department of Neurological Surgery, University of California, Los Angeles, CA, USA
J Neurosurg Spine 14:758-64. 2011..In this paper, the authors compare the clinical outcome of mini-open resection of intradural thoracolumbar tumors with a standard open technique...
Sarcoma and the spinal columnVincent Y Wang
Department of Neurological Surgery, University of California, 505 Parnassus Avenue, Room M779, San Francisco, CA 94143 0112, USA
Neurosurg Clin N Am 19:71-80. 2008..Chemotherapy and radiation therapy have variable effects on these tumors. With recent advances in surgical techniques and development of new chemotherapy protocols, survival and local control are both improving...
Pitfalls of calculating hospital readmission rates based on nonvalidated administrative data sets: : presented at the 2012 Joint Spine Section Meeting: clinical articleBeejal Y Amin
Department of Neurosurgery, University of California, San Francisco, California 94143, USA
J Neurosurg Spine 18:134-8. 2013....
Spine and spinal cord emergencies: vascular and infectious causesVincent Y Wang
Department of Neurological Surgery, University of California, 505 Parnassus Avenue, MS112, San Francisco, CA 94143, USA
Neuroimaging Clin N Am 20:639-50. 2010..The authors discuss several infectious and vascular spinal emergencies, including epidural abscess, nontraumatic epidural hematoma, vascular malformations, and spinal cord infarction...
Operative management of adult high-grade lumbosacral spondylolisthesisFrank L Acosta
Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA
Neurosurg Clin N Am 18:249-54. 2007..Posterolateral pedicle screw-rod fixation has improved rates of arthrodesis compared with traditional in situ fusions. Nevertheless, complications with operative management of high-grade spondylolisthesis can be severe...
Stereotactic body radiotherapy is effective salvage therapy for patients with prior radiation of spinal metastasesArjun Sahgal
Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, USA
Int J Radiat Oncol Biol Phys 74:723-31. 2009..To provide actuarial outcomes and dosimetric data for spinal/paraspinal metastases, with and without prior radiation, treated with stereotactic body radiotherapy (SBRT)...
Lumbar spinal stenosis, cauda equina syndrome, and multiple lumbosacral radiculopathiesPhillip B Storm
Department of Neurological Surgery, Johns Hopkins University School of Medicine, 725 North Wolfe Street, 817 Hunterian Boulevard, Baltimore, MD 21205, USA
Phys Med Rehabil Clin N Am 13:713-33, ix. 2002..The article reviews the anatomy and pathophysiology, clinical syndrome, diagnostic workup, and natural history of lumbar spinal stenosis to aid in proper diagnosis and treatment...
Flatback syndromeDaniel C Lu
Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143 0112, USA
Neurosurg Clin N Am 18:289-94. 2007..The usual etiology is iatrogenic, through previous fusions or with extension instrumentation. Surgical treatments described include extension osteotomy (Smith-Petersen), pedicle subtraction osteotomy, and polysegmental osteotomies...
Vulnerability of the subcostal nerve to injury during bone graft harvesting from the iliac crestDean Chou
Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Neurosurg Spine 1:87-9. 2004..This nerve is very vulnerable to injury when harvesting bone from the anterior iliac crest. Knowledge of the anatomy may decrease the risk of injury to this nerve...
Minimally invasive compared to open microdiscectomy for lumbar disc herniationDarryl Lau
Department of Neurosurgery, University of California at San Francisco, 505 Parnassus Avenue, Box 0112, San Francisco, California 94143 0112, USA
J Clin Neurosci 18:81-4. 2011..There were no statistically significant differences between the minimally invasive and open groups in terms of operative time, length of stay, neurological outcome, complication rate, or change in pain score (pain improvement)...
Pregnancy-related vertebral hemangioma. Case report, review of the literature, and management algorithmJohn H Chi
Department of Neurological Surgery, San Francisco General Hospital, University of California, San Francisco, California, USA
Neurosurg Focus 19:E7. 2005..Observation should be considered for symptomatic patients at greater than 32 weeks gestation. Surgery should be considered for patients with severe neurological deficits at less than 32 weeks of gestation...
Anterior C1-2 osteochondroma presenting with dysphagia and sleep apneaVincent Wang
Department of Neurological Surgery, University of California San Francisco, 505 Parnassus Ave Rm M779, San Francisco, CA 94143 0112, USA
J Clin Neurosci 16:581-2. 2009..To our knowledge, this is the first case of a sporadic osteochondroma arising from the anterior arch of the C1 vertebra causing dysphagia and obstructive apnea in a pediatric patient...
Neurolisteriosis presenting as cervical myelitis in an immunocompetent patientS Andrew Josephson
Department of Neurology, University of California, San Francisco, CA 94143-0114, USA
Neurology 66:1122-3. 2006
Dynamic stabilization versus fusion for treatment of degenerative spine conditionsDean Chou
University of California, San Francisco, California, USA
Evid Based Spine Care J 2:33-42. 2011..Conclusions:  There are no clinical data from comparative studies supporting the use of dynamic stabilization devices over standard fusion techniques...
Efficacy of interspinous device versus surgical decompression in the treatment of lumbar spinal stenosis: a modified network analysisDean Chou
University of California, San Francisco, CA, USA
Evid Based Spine Care J 2:45-56. 2011....
Lumbar subdural hematoma from intracranial subarachnoid hemorrhage presenting with bilateral foot drop: case reportJames S Waldron
Department of Neurological Surgery, University of California, San Francisco, California 94143, USA
Neurosurgery 68:E835-9; discussion E839. 2011..We report a patient with lumbar subdural hematoma secondary to intracranial subarachnoid hemorrhage (SAH) presenting with bilateral foot drop and describe our management...
Von Hippel-Lindau disease in pregnancy: a brief reviewMelanie G Hayden
Department of Neurosurgery, Stanford University Medical Center, 300 Pasteur Road, Stanford, California 94305, USA
J Clin Neurosci 16:611-3. 2009..Introducing this review is a description of our patient with VHL, who uniquely presented in pregnancy with a cervical hemangioblastoma...
Conus medullaris syndrome without lower-extremity involvement in L-1 burst fractures: report of four casesDean Chou
Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona 85013, USA
J Neurosurg Spine 4:265-9. 2006..The authors report four cases of L-1 burst fractures in which conus medullaris dysfunction was the sole neurological injury in the absence of lower-extremity involvement...
Biomechanical comparison of two new atlantoaxial fixation techniques with C1-2 transarticular screw-graft fixationRoger Hartl
Spinal Biomechanics Laboratory, Division of Neurological Surgery, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, Arizona 85013, USA
J Neurosurg Spine 5:336-42. 2006..The authors compared these techniques with the gold-standard, interspinous graft-augmented C1-2 transarticular screw fixation and with a control C1-2 interspinous graft fixation procedure alone...
