Research Topics
| Tae W ChongSummaryAffiliation: University of Virginia Country: USA Publications
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Detail Information
Publications
Primary human hepatocytes in spheroid formation to study hepatitis C infectionTae W Chong
Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia 22908, USA
J Surg Res 130:52-7. 2006..As hepatocytes are the primary reservoir for the virus in vivo, we report on a model using primary human hepatocytes cultured in spheroid formation...
HCV infection of the transplanted liver: changing CD81 and HVR1 variants immediately after liver transplantationMichael G Hughes
Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia, USA
Am J Transplant 5:2504-13. 2005..In conclusion, HVR1 quasispecies variants differentially associate with, and infect allografts, after liver transplantation. Additionally, allografts express variable amounts of CD81 after transplantation...
Does body mass index affect infection-related outcomes in the intensive care unit?Robert L Smith
Department of Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
Surg Infect (Larchmt) 8:581-8. 2007..We hypothesized that increasing BMI would be an independent predictor of higher mortality rates in the surgical/trauma ICU...
Cost of Gram-negative resistanceHeather L Evans
Department of Surgery, University of Virginia Health System, Charlottesville, VA, USA
Crit Care Med 35:89-95. 2007..We wished to test the hypothesis that rGNR infections are associated with higher resource utilization...
Choosing antibiotics for intra-abdominal infections: what do we mean by "high risk"?Brian R Swenson
Department of Surgery, University of Virginia, Charlottesville, Virginia 22908 0709, USA
Surg Infect (Larchmt) 10:29-39. 2009..The purpose of this study was to investigate patient characteristics associated with a high risk of isolation of resistant pathogens from an intra-abdominal source...
Can we define the ideal duration of antibiotic therapy?Traci L Hedrick
University of Virginia Surgical Infectious Disease Laboratory, Charlottesville, VA 22908, USA
Surg Infect (Larchmt) 7:419-32. 2006..We also sought to investigate the difference between a fixed duration of therapy and one based on physiologic measures such as fever and leukocytosis...
Reduction in rates of methicillin-resistant Staphylococcus aureus infection after introduction of quarterly linezolid-vancomycin cycling in a surgical intensive care unitRobert L Smith
Department of Surgery, University of Virginia, Charlottesville, Virginia 22908 0709, USA
Surg Infect (Larchmt) 9:423-31. 2008..Creative interventions may be required to reverse or stabilize this trend...
Effect of an intensive care unit rotating empiric antibiotic schedule on the development of hospital-acquired infections on the non-intensive care unit wardMichael G Hughes
Department of Surgery, University of Virginia, Charlottesville 22908, USA
Crit Care Med 32:53-60. 2004....
Does prior transfusion worsen outcomes from infection in surgical patients?Michael G Hughes
Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia 22908, USA
Surg Infect (Larchmt) 4:335-43. 2003..The objective of this study was to determine the effect of transfusion on outcomes among infected surgical patients...
Comparison of fungal and nonfungal infections in a broad-based surgical patient populationMichael G Hughes
Department of Surgery, Surgical Infectious Disease Laboratory, University of Virginia, Charlottesville, Virginia 22908, USA
Surg Infect (Larchmt) 6:55-64. 2005..Our aim was to compare fungal and nonfungal infections among a diverse surgical patient population...
E2 quasispecies specificity of hepatitis C virus association with allografts immediately after liver transplantationMichael G Hughes
University of Virginia, Department of Surgery, Surgical Infectious Disease Laboratory, Charlottesville, VA, USA
Liver Transpl 10:208-16. 2004..02 and P = 0.04, respectively). Immediately after transplantation but before actual infection, liver allografts select out from the infecting serum inoculum a less heterogeneous, more closely related population of quasispecies variants...
Does the addition of glutamine to enteral feeds affect patient mortality?Alison Saalwachter Schulman
Department of Surgery, University of Virginia Health System, Charlottesville, VA, USA
Crit Care Med 33:2501-6. 2005..The objective was to study in a prospective fashion the effects of adding glutamine to standard or immune-modulated (supplemented with omega-3 fatty acids, beta-carotene, and amino acids such as glutamine and arginine) tube feeds...
Impact of immunomodulatory oligodeoxynucleotides on cytokine production in the lipopolysaccharide-stimulated human whole blood modelRobert L Smith
Surgical Infectious Disease Research Laboratory, Department of Surgery, University of Virginia Health System, Charlottesville, VA 22908, USA
Surgery 136:464-72. 2004..With further examination, we may find that these observed immunomodulatory differences could potentially be exploited for therapeutic benefit...
Contact isolation in surgical patients: a barrier to care?Heather L Evans
Department of Surgery, UVA Health System, Charlottesville, VA 22908, USA
Surgery 134:180-8. 2003..Contact isolation is commonly used to prevent transmission of resistant organisms. We hypothesized that contact isolation negatively impacts the amount of direct patient care...
Subfascial endoscopic perforating vein surgery (SEPS) for the treatment of venous ulcersTae W Chong
University of Virginia, Charlottesville, VA 22908, USA
Ostomy Wound Manage 51:26-31. 2005..Significant efforts have been devoted to elucidating the exact mechanism of skin breakdown from venous hypertension but the pathophysiology of this process is still not understood...
Adenosine A2A receptor activation reduces inflammation and preserves pulmonary function in an in vivo model of lung transplantationT Brett Reece
Department of Surgery, University of Virginia Health System, PO Box 801359, Charlottesville, VA 22908, USA
J Thorac Cardiovasc Surg 129:1137-43. 2005..We hypothesized that adenosine A 2A receptor activation by ATL-146e during the initial reperfusion period preserves pulmonary function and attenuates inflammation in a porcine model of lung transplantation...
