Mario Chojkier

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Signal transduction in the liver: C/EBPbeta modulates cell proliferation and survival
    Martina Buck
    Department of Medicine and Center for Molecular Genetics, Veterans Affairs Healthcare System and University of California San Diego, San Diego, CA 92161, USA
    Hepatology 37:731-8. 2003
  2. pmc Pioglitazone decreases hepatitis C viral load in overweight, treatment naïve, genotype 4 infected-patients: a pilot study
    Mario Chojkier
    Department of Medicine, San Diego VA Healthcare System, San Diego, California, United States of America
    PLoS ONE 7:e31516. 2012
  3. ncbi request reprint Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids
    Mario Chojkier
    Department of Medicine and Center for Molecular Genetics, Veterans Affairs Healthcare System and University of California San Diego, VAMC 111 D, San Diego, CA 92161, USA
    J Hepatol 39:437-46. 2003
  4. ncbi request reprint Troglitazone and liver injury: in search of answers
    Mario Chojkier
    Department of Medicine and Cancer Center, Veterans Affairs Healthcare System and University of California, San Diego, CA 92161, USA
    Hepatology 41:237-46. 2005
  5. ncbi request reprint Inhibition of albumin synthesis in chronic diseases: molecular mechanisms
    Mario Chojkier
    Department of Medicine and Cancer Center, University of California San Diego, San Diego, CA 92161, USA
    J Clin Gastroenterol 39:S143-6. 2005
  6. ncbi request reprint C/EBPbeta associates with caspase 8 complex proteins and modulates apoptosis in hepatic stellate cells
    Martina Buck
    Department of Medicine and Cancer Center, Veterans Healthcare Medical Center and University of California, San Diego, CA 92161, USA
    J Clin Gastroenterol 41:S295-9. 2007
  7. pmc A ribosomal S-6 kinase-mediated signal to C/EBP-beta is critical for the development of liver fibrosis
    Martina Buck
    Department of Medicine and Moores Cancer Center, University of California at San Diego, La Jolla, California, United States of America
    PLoS ONE 2:e1372. 2007
  8. pmc C/EBPβ-Thr217 phosphorylation signaling contributes to the development of lung injury and fibrosis in mice
    Martina Buck
    Department of Medicine, VA Healthcare Center, San Diego, California, United States of America
    PLoS ONE 6:e25497. 2011
  9. pmc Gastric adenocarcinoma inducing portal hypertension: a rare presentation
    Pradipta Ghosh
    Department of Medicine, Division of Gastroenterology and Hepatology, University of California, San Diego, CA 92161, USA
    World J Gastroenterol 13:960-3. 2007
  10. ncbi request reprint C/EBPbeta phosphorylation rescues macrophage dysfunction and apoptosis induced by anthrax lethal toxin
    Martina Buck
    Department of Medicine, University of California San Diego, and Veterans Affairs Healthcare System, San Diego, CA 92161, USA
    Am J Physiol Cell Physiol 293:C1788-96. 2007

Research Grants

  1. C/EBP BETA IN HEPATOCYTE GENE EXPRESSION & PROLIFERATION
    Mario Chojkier; Fiscal Year: 2002
  2. HEPATIC FIBROSIS: MOLECULAR MECHANISMS
    Mario Chojkier; Fiscal Year: 2009
  3. C/EBP BETA IN HEPATOCYTE GENE EXPRESSION & PROLIFERATION
    Mario Chojkier; Fiscal Year: 2001
  4. HEPATIC FIBROSIS: MOLECULAR MECHANISMS
    Mario Chojkier; Fiscal Year: 2005
  5. HEPATIC FIBROSIS: MOLECULAR MECHANISMS
    Mario Chojkier; Fiscal Year: 2006
  6. HEPATIC FIBROSIS: MOLECULAR MECHANISMS
    Mario Chojkier; Fiscal Year: 2007
  7. C/EBP beta SIGNALS HEPATOCYTE PROLIFERATION AND SURVIVAL
    Mario Chojkier; Fiscal Year: 2007
  8. HEPATIC FIBROSIS: MOLECULAR MECHANISMS
    Mario Chojkier; Fiscal Year: 2009
  9. C/EBP BETA IN HEPATOCYTE GENE EXPRESSION & PROLIFERATION
    Mario Chojkier; Fiscal Year: 2001
  10. C/EBP BETA IN HEPATOCYTE GENE EXPRESSION & PROLIFERATION
    Mario Chojkier; Fiscal Year: 1999

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Signal transduction in the liver: C/EBPbeta modulates cell proliferation and survival
    Martina Buck
    Department of Medicine and Center for Molecular Genetics, Veterans Affairs Healthcare System and University of California San Diego, San Diego, CA 92161, USA
    Hepatology 37:731-8. 2003
  2. pmc Pioglitazone decreases hepatitis C viral load in overweight, treatment naïve, genotype 4 infected-patients: a pilot study
    Mario Chojkier
    Department of Medicine, San Diego VA Healthcare System, San Diego, California, United States of America
    PLoS ONE 7:e31516. 2012
    ..A secondary aim was to assess whether Prednisone, a drug that induces insulin resistance and stimulates HCV viral entry and replication in replicon culture systems, increases HCV viral load in this population...
  3. ncbi request reprint Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids
    Mario Chojkier
    Department of Medicine and Center for Molecular Genetics, Veterans Affairs Healthcare System and University of California San Diego, VAMC 111 D, San Diego, CA 92161, USA
    J Hepatol 39:437-46. 2003
  4. ncbi request reprint Troglitazone and liver injury: in search of answers
    Mario Chojkier
    Department of Medicine and Cancer Center, Veterans Affairs Healthcare System and University of California, San Diego, CA 92161, USA
    Hepatology 41:237-46. 2005
  5. ncbi request reprint Inhibition of albumin synthesis in chronic diseases: molecular mechanisms
    Mario Chojkier
    Department of Medicine and Cancer Center, University of California San Diego, San Diego, CA 92161, USA
    J Clin Gastroenterol 39:S143-6. 2005
    ....
  6. ncbi request reprint C/EBPbeta associates with caspase 8 complex proteins and modulates apoptosis in hepatic stellate cells
    Martina Buck
    Department of Medicine and Cancer Center, Veterans Healthcare Medical Center and University of California, San Diego, CA 92161, USA
    J Clin Gastroenterol 41:S295-9. 2007
    ..To analyze the role of C/EBPbeta phosphorylation on hepatic stellate cell survival/cell death...
  7. pmc A ribosomal S-6 kinase-mediated signal to C/EBP-beta is critical for the development of liver fibrosis
    Martina Buck
    Department of Medicine and Moores Cancer Center, University of California at San Diego, La Jolla, California, United States of America
    PLoS ONE 2:e1372. 2007
    ..Here we show that activation of RSK and phosphorylation of C/EBPbeta on Thr217 in activated HSC is critical for the progression of liver fibrosis...
  8. pmc C/EBPβ-Thr217 phosphorylation signaling contributes to the development of lung injury and fibrosis in mice
    Martina Buck
    Department of Medicine, VA Healthcare Center, San Diego, California, United States of America
    PLoS ONE 6:e25497. 2011
    ....
  9. pmc Gastric adenocarcinoma inducing portal hypertension: a rare presentation
    Pradipta Ghosh
    Department of Medicine, Division of Gastroenterology and Hepatology, University of California, San Diego, CA 92161, USA
    World J Gastroenterol 13:960-3. 2007
    ..Pagetoid spread of cancer cells likely caused early metastasis and the unusual presentation. We also discussed the pathophysiology of development of portal hypertension in association with malignancies...
  10. ncbi request reprint C/EBPbeta phosphorylation rescues macrophage dysfunction and apoptosis induced by anthrax lethal toxin
    Martina Buck
    Department of Medicine, University of California San Diego, and Veterans Affairs Healthcare System, San Diego, CA 92161, USA
    Am J Physiol Cell Physiol 293:C1788-96. 2007
    ..These findings suggest that C/EBPbeta may play a critical role in anthrax pathogenesis, at least in macrophages...
  11. ncbi request reprint Novel inflammatory biomarkers of portal pressure in compensated cirrhosis patients
    Martina Buck
    Veterans Affairs San Diego Healthcare System, San Diego, CA Department of Medicine, University of California, San Diego, La Jolla, CA Biomedical Sciences Program, University of California, San Diego, La Jolla, CA
    Hepatology 59:1052-9. 2014
    ..Our diagnostic test was not efficient in predicting HVPG ≥ 12 mmHg...
  12. ncbi request reprint The effect of hepatic insufficiency on the safety and pharmacokinetics of paricalcitol (Zemplar)
    Robert A Carr
    Department of Clinical Pharmacokinetics, Abbott Laboratories, Abbott Park, Illinois 60064 6104, USA
    Nephron Clin Pract 103:c100-5. 2006
    ..Paricalcitol is highly protein bound, extensively metabolized and eliminated primarily by hepatobiliary excretion. This study was designed to determine if hepatic disease alters the pharmacokinetics or affects the safety of paricalcitol...

Research Grants26

  1. C/EBP BETA IN HEPATOCYTE GENE EXPRESSION & PROLIFERATION
    Mario Chojkier; Fiscal Year: 2002
    ....
  2. HEPATIC FIBROSIS: MOLECULAR MECHANISMS
    Mario Chojkier; Fiscal Year: 2009
    ..The regulation of FLIPL activity by MAPK-RSK-C/EBP( signaling in stellate cells. 2. The role of C/EBP( phosphorylation on stellate cell survival. 3. The modulation of stellate cell survival in C/EBP(Glu217 transgenic mice. ..
  3. C/EBP BETA IN HEPATOCYTE GENE EXPRESSION & PROLIFERATION
    Mario Chojkier; Fiscal Year: 2001
    ....
  4. HEPATIC FIBROSIS: MOLECULAR MECHANISMS
    Mario Chojkier; Fiscal Year: 2005
    ..The regulation of FLIPL activity by MAPK-RSK-C/EBP( signaling in stellate cells. 2. The role of C/EBP( phosphorylation on stellate cell survival. 3. The modulation of stellate cell survival in C/EBP(Glu217 transgenic mice. ..
  5. HEPATIC FIBROSIS: MOLECULAR MECHANISMS
    Mario Chojkier; Fiscal Year: 2006
    ..The regulation of FLIPL activity by MAPK-RSK-C/EBP( signaling in stellate cells. 2. The role of C/EBP( phosphorylation on stellate cell survival. 3. The modulation of stellate cell survival in C/EBP(Glu217 transgenic mice. ..
  6. HEPATIC FIBROSIS: MOLECULAR MECHANISMS
    Mario Chojkier; Fiscal Year: 2007
    ..The regulation of FLIPL activity by MAPK-RSK-C/EBP( signaling in stellate cells. 2. The role of C/EBP( phosphorylation on stellate cell survival. 3. The modulation of stellate cell survival in C/EBP(Glu217 transgenic mice. ..
  7. C/EBP beta SIGNALS HEPATOCYTE PROLIFERATION AND SURVIVAL
    Mario Chojkier; Fiscal Year: 2007
    ..These studies are relevant to the hepatocyte proliferation and survival characteristic of many physiological and pathological conditions, including hepatocellular injury, liver regeneration and hepatocellular carcinoma. ..
  8. HEPATIC FIBROSIS: MOLECULAR MECHANISMS
    Mario Chojkier; Fiscal Year: 2009
    ..The regulation of FLIPL activity by MAPK-RSK-C/EBP( signaling in stellate cells. 2. The role of C/EBP( phosphorylation on stellate cell survival. 3. The modulation of stellate cell survival in C/EBP(Glu217 transgenic mice. ..
  9. C/EBP BETA IN HEPATOCYTE GENE EXPRESSION & PROLIFERATION
    Mario Chojkier; Fiscal Year: 2001
    ....
  10. C/EBP BETA IN HEPATOCYTE GENE EXPRESSION & PROLIFERATION
    Mario Chojkier; Fiscal Year: 1999
    ....
  11. C/EBP BETA IN HEPATOCYTE GENE EXPRESSION & PROLIFERATION
    Mario Chojkier; Fiscal Year: 2000
    ....
  12. C/EBP BETA IN HEPATOCYTE GENE EXPRESSION & PROLIFERATION
    Mario Chojkier; Fiscal Year: 2000
    ....