Research Topics
| Seok Ki ChoiSummaryAffiliation: University of Michigan Country: USA Publications
| Collaborators
|
Detail Information
Publications
Dendrimer-based multivalent vancomycin nanoplatform for targeting the drug-resistant bacterial surfaceSeok Ki Choi
Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA
ACS Nano 7:214-28. 2013....
Photochemical release of methotrexate from folate receptor-targeting PAMAM dendrimer nanoconjugateSeok Ki Choi
Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, MI 48109, USA
Photochem Photobiol Sci 11:653-60. 2012....
A photochemical approach for controlled drug release in targeted drug deliverySeok Ki Choi
Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, MI 48109, USA
Bioorg Med Chem 20:1281-90. 2012..The rate of the drug release varies in response to multiple control parameters, including linker design, light wavelength, exposure time, and the pH of the medium where the drug release occurs...
Light-controlled release of caged doxorubicin from folate receptor-targeting PAMAM dendrimer nanoconjugateSeok Ki Choi
Michigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Medical School, Ann Arbor, MI 48109, USA
Chem Commun (Camb) 46:2632-4. 2010..We report the synthesis and in vitro evaluation of folate receptor-targeted nanoconjugate that releases its therapeutic payload via a photochemical mechanism...
Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeuticThommey P Thomas
Michigan Nanotechnology Institute for Medicine and Biological Sciences, Ann Arbor, Michigan 48109, United States
Mol Pharm 9:2669-76. 2012..The newly synthesized G5-MTX(n) conjugate may serve as a FR-targeted chemotherapeutic with potential for cancer therapy...
Dendrimer-based multivalent methotrexates as dual acting nanoconjugates for cancer cell targetingMing Hsin Li
Michigan Nanotechnology Institute for Medicine and Biological Sciences, and Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA
Eur J Med Chem 47:560-72. 2012....
Design of riboflavin-presenting PAMAM dendrimers as a new nanoplatform for cancer-targeted deliveryThommey P Thomas
Michigan Nanotechnology Institute for Medicine and Biological Sciences, Department of Internal Medicine, Division of Allergy, University of Michigan, Ann Arbor, MI 48109, USA
Bioorg Med Chem Lett 20:5191-4. 2010....
Paclitaxel-conjugated PAMAM dendrimers adversely affect microtubule structure through two independent modes of actionErika N Cline
Cellular and Molecular Biology Graduate Program, University of Michigan, Ann Arbor, MI 48109, USA
Biomacromolecules 14:654-64. 2013..Our results provide mechanistic insights into the cytotoxicity of paclitaxel-conjugated PAMAM dendrimers and uncover unexpected risks of using such conjugates therapeutically...
