Regine Choe

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Transabdominal near infrared oximetry of hypoxic stress in fetal sheep brain in utero
    Regine Choe
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 100:12950-4. 2003
  2. ncbi request reprint Diffuse optical tomography with spectral constraints and wavelength optimization
    Alper Corlu
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Appl Opt 44:2082-93. 2005
  3. ncbi request reprint Diffuse optical measurement of blood flow in breast tumors
    Turgut Durduran
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Opt Lett 30:2915-7. 2005
  4. pmc Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography
    Regine Choe
    University of Pennsylvania, Department of Physics, 209 S 33rd Street, Philadelphia, Pennsylvania 19104, USA
    J Biomed Opt 14:024020. 2009
  5. ncbi request reprint Diffuse optical tomography of breast cancer during neoadjuvant chemotherapy: a case study with comparison to MRI
    Regine Choe
    Department of Physics and Astronomy, University of Pennsylvania, 209 South 33rd Street, Philadelphia, Pennsylvania 19104 6396, USA
    Med Phys 32:1128-39. 2005
  6. ncbi request reprint Diffuse optical tomography & spectroscopy in breast cancer characterization & therapy monitoring at UPENN
    Regine Choe
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:6335-7. 2009
  7. pmc Direct measurement of tissue blood flow and metabolism with diffuse optics
    Rickson C Mesquita
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA
    Philos Trans A Math Phys Eng Sci 369:4390-406. 2011
  8. ncbi request reprint Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy
    Chao Zhou
    University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania 19104, USA
    J Biomed Opt 12:051903. 2007
  9. pmc Optical malignancy parameters for monitoring progression of breast cancer neoadjuvant chemotherapy
    David R Busch
    Dept of Physics and Astronomy, University of Pennsylvania, 209 S 33rd St, Philadelphia, PA 19104 USA
    Biomed Opt Express 4:105-21. 2013
  10. pmc Computer aided automatic detection of malignant lesions in diffuse optical mammography
    David R Busch
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Med Phys 37:1840-9. 2010

Detail Information

Publications20

  1. pmc Transabdominal near infrared oximetry of hypoxic stress in fetal sheep brain in utero
    Regine Choe
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA
    Proc Natl Acad Sci U S A 100:12950-4. 2003
    ..Fetal hypoxia was detected. Good agreement was found between fetal blood saturation determined by the transabdominal NIR method and arterial and venous fetal blood saturation quantified from fetal blood samples by using a hemoximeter...
  2. ncbi request reprint Diffuse optical tomography with spectral constraints and wavelength optimization
    Alper Corlu
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Appl Opt 44:2082-93. 2005
    ..Here the technique is described and tested in detail, and optimum wavelength sets for a broad range of chromophore combinations are discovered and analyzed...
  3. ncbi request reprint Diffuse optical measurement of blood flow in breast tumors
    Turgut Durduran
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Opt Lett 30:2915-7. 2005
    ..Increased blood flow was observed in tumor regions relative to healthy tissue, and control subjects did not exhibit significant blood flow heterogeneity. The measurements introduce a new optical contrast for diffuse optical mammography...
  4. pmc Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography
    Regine Choe
    University of Pennsylvania, Department of Physics, 209 S 33rd Street, Philadelphia, Pennsylvania 19104, USA
    J Biomed Opt 14:024020. 2009
    ..90 to 0.99, suggesting good discriminatory power. The data demonstrate that benign and malignant lesions can be distinguished by quantitative three-dimensional DOT...
  5. ncbi request reprint Diffuse optical tomography of breast cancer during neoadjuvant chemotherapy: a case study with comparison to MRI
    Regine Choe
    Department of Physics and Astronomy, University of Pennsylvania, 209 South 33rd Street, Philadelphia, Pennsylvania 19104 6396, USA
    Med Phys 32:1128-39. 2005
    ..A decrease in total hemoglobin concentration contrast between tumor and normal tissue was also observed over time. The results demonstrate the potential of DOT for measuring physiological parameters of breast lesions during chemotherapy...
  6. ncbi request reprint Diffuse optical tomography & spectroscopy in breast cancer characterization & therapy monitoring at UPENN
    Regine Choe
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:6335-7. 2009
    ....
  7. pmc Direct measurement of tissue blood flow and metabolism with diffuse optics
    Rickson C Mesquita
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA
    Philos Trans A Math Phys Eng Sci 369:4390-406. 2011
    ....
  8. ncbi request reprint Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy
    Chao Zhou
    University of Pennsylvania, Department of Physics and Astronomy, Philadelphia, Pennsylvania 19104, USA
    J Biomed Opt 12:051903. 2007
    ..The hybrid approach also enables construction of indices reflecting tissue metabolic rate of oxygen, which may provide new insights about therapy mechanisms...
  9. pmc Optical malignancy parameters for monitoring progression of breast cancer neoadjuvant chemotherapy
    David R Busch
    Dept of Physics and Astronomy, University of Pennsylvania, 209 S 33rd St, Philadelphia, PA 19104 USA
    Biomed Opt Express 4:105-21. 2013
    ..Though preliminary, the study shows how to use the malignancy parameter for separating responders from partial-responders and demonstrates the potential utility of the methodology compared to traditional DOT quantification schemes...
  10. pmc Computer aided automatic detection of malignant lesions in diffuse optical mammography
    David R Busch
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Med Phys 37:1840-9. 2010
    ..The methodology is tested in a population of 35 biopsy-confirmed malignant lesions...
  11. pmc Noninvasive measurement of cerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults
    Meeri N Kim
    Department of Physics and Astronomy, University of Pennsylvania, 209 South 33rd Street, Philadelphia, PA 19104, USA
    Neurocrit Care 12:173-80. 2010
    ....
  12. ncbi request reprint Noninvasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study
    Ulas Sunar
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6396, USA
    J Biomed Opt 11:064021. 2006
    ..0+/-8.1) [microM] at the end of the fourth week of therapy. These preliminary results suggest daily diffuse-optics-based therapy monitoring is feasible during the first two weeks and may have clinical promise...
  13. ncbi request reprint Uniqueness and wavelength optimization in continuous-wave multispectral diffuse optical tomography
    Alper Corlu
    Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Opt Lett 28:2339-41. 2003
    ..Application of these concepts should significantly improve the fidelity of continuous-wave diffuse near-infrared optical tomography in tissues...
  14. pmc Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial Doppler ultrasound
    Erin M Buckley
    Department of Physics and Astronomy, University of Pennsylvania, 209 S 33rd St, Philadelphia, PA 19104, USA
    Opt Express 17:12571-81. 2009
    ....
  15. pmc Transcranial optical monitoring of cerebrovascular hemodynamics in acute stroke patients
    Turgut Durduran
    Departments of Radiology, University of Pennsylvania, PA, USA
    Opt Express 17:3884-902. 2009
    ..Moreover, the presence of an ipsilateral infarct was a significant effect for all parameters. Results are consistent with the notion of impaired CBF autoregulation in the infarcted hemisphere...
  16. doi request reprint Blood flow reduction in breast tissue due to mammographic compression
    David R Busch
    Division of Neurology, Children s Hospital of Philadelphia, Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA, 19104 Electronic address
    Acad Radiol 21:151-61. 2014
    ..Because many breast-imaging technologies derive contrast from the deformed breast, these load-dependent vascular responses affect contrast agent-enhanced and hemoglobin-based breast imaging...
  17. pmc Comparison of diffuse optical tomography of human breast with whole-body and breast-only positron emission tomography
    Soren D Konecky
    Department of Physics and Astronomy, University of Pennsylvania, 209 South 33rd Street, Philadelphia, Pennsylvania 19104, USA
    Med Phys 35:446-55. 2008
    ..In light of these observations, we suggest potential benefits of combining both PET and DOT for characterization of breast lesions...
  18. pmc Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects
    Turgut Durduran
    ICFO Institut de Ciencies Fotoniques, Av Canal Olimpic s n, Castelldefels 08860, Spain
    J Biomed Opt 15:037004. 2010
    ..7, p=0.01). The study demonstrates use of NIRS-DCS on a critically ill neonatal population, and the results indicate that the optical technology is a promising clinical method for monitoring this population...
  19. doi request reprint Non-invasive assessment of tumor neovasculature: techniques and clinical applications
    Rodolfo Perini
    Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    Cancer Metastasis Rev 27:615-30. 2008
    ....
  20. ncbi request reprint Standardized platform for coregistration of nonconcurrent diffuse optical and magnetic resonance breast images obtained in different geometries
    Fred S Azar
    Siemens Corporate Research, Department of Imaging and Visualization, 755 College Road East Princeton, New Jersy 08540, USA
    J Biomed Opt 12:051902. 2007
    ..The average THC in the tumorous regions is one to three standard deviations larger than the overall breast average THC for all patients...