Charles Y Chiu

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc A novel rhabdovirus associated with acute hemorrhagic fever in central Africa
    Gilda Grard
    Viral Emergent Diseases unit, Centre International de Recherches Medicales de Franceville, Franceville, Gabon
    PLoS Pathog 8:e1002924. 2012
  2. pmc In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer
    Deanna Lee
    Department of Laboratory Medicine, University of San Francisco, San Francisco, California, United States of America
    PLoS ONE 7:e44954. 2012
  3. pmc A novel bocavirus in canine liver
    Linlin Li
    Blood Systems Research Institute, San Francisco, CA, USA
    Virol J 10:54. 2013
  4. doi request reprint Viral pathogen discovery
    Charles Y Chiu
    Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA
    Curr Opin Microbiol 16:468-78. 2013
  5. pmc A novel adenovirus species associated with an acute respiratory outbreak in a baboon colony and evidence of coincident human infection
    Charles Y Chiu
    Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA
    MBio 4:e00084. 2013
  6. pmc Cultivation and serological characterization of a human Theiler's-like cardiovirus associated with diarrheal disease
    C Y Chiu
    Department of Laboratory Medicine, University of California, San Francisco, 185 Berry Street, Box 0134, San Francisco, CA 94143 0134, USA
    J Virol 84:4407-14. 2010
  7. pmc Experimental cross-species infection of common marmosets by titi monkey adenovirus
    Guixia Yu
    Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 8:e68558. 2013
  8. pmc Discovery of a novel polyomavirus in acute diarrheal samples from children
    Guixia Yu
    Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
    PLoS ONE 7:e49449. 2012
  9. pmc The complete genome of klassevirus - a novel picornavirus in pediatric stool
    Alexander L Greninger
    Howard Hughes Medical Institute, Departments of Medicine, Biochemistry, and Microbiology, University of California, San Francisco, California 94143, USA
    Virol J 6:82. 2009
  10. doi request reprint Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis
    Alexander L Greninger
    Department of Laboratory Medicine, University of California, San Francisco, CA, 94107, USA
    Genome Med 7:99. 2015

Collaborators

Detail Information

Publications30

  1. pmc A novel rhabdovirus associated with acute hemorrhagic fever in central Africa
    Gilda Grard
    Viral Emergent Diseases unit, Centre International de Recherches Medicales de Franceville, Franceville, Gabon
    PLoS Pathog 8:e1002924. 2012
    ..The natural animal reservoir host or arthropod vector and precise mode of transmission for the virus remain unclear. BASV is an emerging human pathogen associated with acute hemorrhagic fever in Africa...
  2. pmc In-depth investigation of archival and prospectively collected samples reveals no evidence for XMRV infection in prostate cancer
    Deanna Lee
    Department of Laboratory Medicine, University of San Francisco, San Francisco, California, United States of America
    PLoS ONE 7:e44954. 2012
    ..These findings reveal no association between XMRV and prostate cancer, and underscore the conclusion that XMRV is not a naturally acquired human infection...
  3. pmc A novel bocavirus in canine liver
    Linlin Li
    Blood Systems Research Institute, San Francisco, CA, USA
    Virol J 10:54. 2013
    ..Two species have been previously reported in dogs, minute virus of canines (MVC), associated with neonatal diseases and fertility disorders; and Canine bocavirus (CBoV), associated with respiratory disease...
  4. doi request reprint Viral pathogen discovery
    Charles Y Chiu
    Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA
    Curr Opin Microbiol 16:468-78. 2013
    ..Downstream studies such as genome assembly, epidemiologic screening, and a culture system or animal model of infection are necessary to establish an association of a candidate pathogen with disease. ..
  5. pmc A novel adenovirus species associated with an acute respiratory outbreak in a baboon colony and evidence of coincident human infection
    Charles Y Chiu
    Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, USA
    MBio 4:e00084. 2013
    ....
  6. pmc Cultivation and serological characterization of a human Theiler's-like cardiovirus associated with diarrheal disease
    C Y Chiu
    Department of Laboratory Medicine, University of California, San Francisco, 185 Berry Street, Box 0134, San Francisco, CA 94143 0134, USA
    J Virol 84:4407-14. 2010
    ..We also demonstrate an acute cardiovirus seroconversion event in a child with diarrhea and vomiting, thus reporting for the first time evidence linking cardiovirus infection to diarrheal disease in humans...
  7. pmc Experimental cross-species infection of common marmosets by titi monkey adenovirus
    Guixia Yu
    Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 8:e68558. 2013
    ..These findings further establish the potential for adenovirus cross-species transmission and provide the basis for development of a monkey model useful for assessing the zoonotic potential of adenoviruses. ..
  8. pmc Discovery of a novel polyomavirus in acute diarrheal samples from children
    Guixia Yu
    Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, USA
    PLoS ONE 7:e49449. 2012
    ..Further studies will be important to determine the association, if any, of MXPyV with disease in humans...
  9. pmc The complete genome of klassevirus - a novel picornavirus in pediatric stool
    Alexander L Greninger
    Howard Hughes Medical Institute, Departments of Medicine, Biochemistry, and Microbiology, University of California, San Francisco, California 94143, USA
    Virol J 6:82. 2009
    ..Modern technologies, especially deep sequencing, allow rapid, high-throughput screening of clinical samples such as stool for new infectious agents associated with human disease...
  10. doi request reprint Rapid metagenomic identification of viral pathogens in clinical samples by real-time nanopore sequencing analysis
    Alexander L Greninger
    Department of Laboratory Medicine, University of California, San Francisco, CA, 94107, USA
    Genome Med 7:99. 2015
    ....
  11. pmc Utility of DNA microarrays for detection of viruses in acute respiratory tract infections in children
    Charles Y Chiu
    Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA, USA
    J Pediatr 153:76-83. 2008
    ..To assess the utility of a panviral DNA microarray platform (Virochip) in the detection of viruses associated with pediatric respiratory tract infections (RTIs)...
  12. doi request reprint Clinical metagenomic identification of Balamuthia mandrillaris encephalitis and assembly of the draft genome: the continuing case for reference genome sequencing
    Alexander L Greninger
    Department of Laboratory Medicine, University of California, 185 Berry Street, Box 0134, San Francisco, CA, 94107, USA
    Genome Med 7:113. 2015
    ..Primary amoebic meningoencephalitis (PAM) is a rare, often lethal, cause of encephalitis, for which early diagnosis and prompt initiation of combination antimicrobials may improve clinical outcomes...
  13. pmc Identification of cardioviruses related to Theiler's murine encephalomyelitis virus in human infections
    Charles Y Chiu
    Department of Biochemistry and Biophysics, University of California, 1700 4th Street, Box 2542, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 105:14124-9. 2008
    ....
  14. doi request reprint A novel outbreak enterovirus D68 strain associated with acute flaccid myelitis cases in the USA (2012-14): a retrospective cohort study
    Alexander L Greninger
    Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA, USA UCSF Abbott Viral Diagnostics and Discovery Center, San Francisco, CA, USA
    Lancet Infect Dis 15:671-82. 2015
    ..We aimed to investigate the association between enterovirus D68 infection and acute flaccid myelitis during the 2014 enterovirus D68 respiratory outbreak in the USA...
  15. pmc Cross-species transmission of a novel adenovirus associated with a fulminant pneumonia outbreak in a new world monkey colony
    Eunice C Chen
    Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, United States of America
    PLoS Pathog 7:e1002155. 2011
    ..The discovery of TMAdV, a novel adenovirus with the capacity to infect both monkeys and humans, suggests that adenoviruses should be monitored closely as potential causes of cross-species outbreaks...
  16. pmc A cloud-compatible bioinformatics pipeline for ultrarapid pathogen identification from next-generation sequencing of clinical samples
    Samia N Naccache
    Department of Laboratory Medicine, UCSF, San Francisco, California 94107, USA UCSF Abbott Viral Diagnostics and Discovery Center, San Francisco, California 94107, USA
    Genome Res 24:1180-92. 2014
    ....
  17. pmc Rosavirus: the prototype of a proposed new genus of the Picornaviridae family
    Tung Gia Phan
    Blood Systems Research Institute, San Francisco, CA, 94118, USA
    Virus Genes 47:556-8. 2013
    ..Based on genetic distance criteria rosavirus qualifies as prototype of a new genus of the Picornaviridae family. ..
  18. pmc Characterization of the Bas-Congo virus glycoprotein and its function in pseudotyped viruses
    Imke Steffen
    Blood Systems Research Institute, San Francisco, California, USA
    J Virol 87:9558-68. 2013
    ..Moreover, serology testing based on BASV-G pseudotype neutralization can be used to uncover the prevalence and importance of BASV as a potential novel human pathogen in the DRC and throughout Central Africa. ..
  19. pmc An ensemble strategy that significantly improves de novo assembly of microbial genomes from metagenomic next-generation sequencing data
    Xutao Deng
    Blood Systems Research Institute, San Francisco, CA 94118, USA Department of Laboratory Medicine, University of California at San Francisco, San Francisco, CA 94107, USA
    Nucleic Acids Res 43:e46. 2015
    ..We demonstrate that this new ensemble strategy tested using in silico spike-in, clinical and environmental NGS datasets achieved significantly better contigs than current approaches. ..
  20. pmc Diagnosis of neuroinvasive astrovirus infection in an immunocompromised adult with encephalitis by unbiased next-generation sequencing
    Samia N Naccache
    Department of Laboratory Medicine, University of California, San Francisco UCSF Abbott Viral Diagnostics and Discovery Center, San Francisco, California
    Clin Infect Dis 60:919-23. 2015
    ..The sequencing and confirmatory studies revealed neuroinvasive infection of the brain by an astrovirus belonging to a recently discovered VA/HMO clade. ..
  21. pmc The perils of pathogen discovery: origin of a novel parvovirus-like hybrid genome traced to nucleic acid extraction spin columns
    Samia N Naccache
    Department of Laboratory Medicine, University of California, San Francisco, California, USA
    J Virol 87:11966-77. 2013
    ....
  22. pmc A metagenomic analysis of pandemic influenza A (2009 H1N1) infection in patients from North America
    Alexander L Greninger
    Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 5:e13381. 2010
    ....
  23. ncbi request reprint Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult
    Charles Y Chiu
    Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA
    Clin Infect Dis 43:e71-6. 2006
    ..This case suggests that the potential severity of disease caused by HPIV-4 in adults may be greater than previously appreciated and illustrates the clinical utility of a microarray for broad-based viral pathogen screening...
  24. doi request reprint Two Rapidly Growing Mycobacterial Species Isolated from a Brain Abscess: First Whole-Genome Sequences of Mycobacterium immunogenum and Mycobacterium llatzerense
    Alexander L Greninger
    Department of Laboratory Medicine, University of California, San Francisco, California, USA UCSF Abbott Viral Diagnostics and Discovery Center, San Francisco, California, USA
    J Clin Microbiol 53:2374-7. 2015
    ..immunogenum and M. llatzerense. The Mycobacterium isolates were distinguishable by molecular methods, and whole-genome sequencing showed <60% pairwise nucleotide identity. ..
  25. pmc Recovery of divergent avian bornaviruses from cases of proventricular dilatation disease: identification of a candidate etiologic agent
    Amy L Kistler
    Departments of Biochemistry, Microbiology and Medicine, Howard Hughes Medical Institute, University of California, San Francisco, 94143, USA
    Virol J 5:88. 2008
    ..For almost 40 years, a viral etiology for PDD has been suspected, but to date no candidate etiologic agent has been reproducibly linked to the disease...
  26. pmc The genome sequence of Lone Star virus, a highly divergent bunyavirus found in the Amblyomma americanum tick
    Andrea Swei
    Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 8:e62083. 2013
    ..This study also underscores the power of deep sequencing analysis in rapidly identifying and sequencing the genomes of viruses of potential clinical and public health significance...
  27. pmc Diagnosis of a critical respiratory illness caused by human metapneumovirus by use of a pan-virus microarray
    Charles Y Chiu
    Department of Biochemistry and Biophysics, University of California, San Francisco at Mission Bay, office BH403C, QB3 Building, 1700 4th Street, San Francisco CA 94158, USA
    J Clin Microbiol 45:2340-3. 2007
    ..The patient's hMPV strain did not grow in viral culture, and only one of five specific reverse transcription-PCR assays for hMPV was positive...
  28. pmc E-Predict: a computational strategy for species identification based on observed DNA microarray hybridization patterns
    Anatoly Urisman
    Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94143, USA
    Genome Biol 6:R78. 2005
    ..We demonstrate the application of the algorithm to viral detection in a set of clinical samples and discuss its relevance to other metagenomic applications...
  29. pmc Thoracic CT findings of novel influenza A (H1N1) infection in immunocompromised patients
    Brett M Elicker
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, 505 Parnassus Avenue, P O Box 0628, San Francisco, CA, 94143, USA
    Emerg Radiol 17:299-307. 2010
    ..A subset of patients with novel influenza A (H1N1) will show findings not typical of viral infection...