Research Topics
Genomes and GenesSpecies | V G ChincharSummaryAffiliation: University of Mississippi Medical Center Country: USA Publications
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Detail Information
Publications
Family Iridoviridae: poor viral relations no longerV G Chinchar
Department of Microbiology, University of Mississippi Medical Center, Jackson, MS, USA
Curr Top Microbiol Immunol 328:123-70. 2009..Herein we describe the molecular and genetic basis of viral replication, pathogenesis, and immunity, and discuss viral ecology with reference to members from each of the invertebrate and vertebrate genera...
Inactivation of viruses infecting ectothermic animals by amphibian and piscine antimicrobial peptidesV G Chinchar
Department of Microbiology, University of Mississippi Medical Center, Jackson, MS 39211, USA
Virology 323:268-75. 2004..These results extend our previous findings and strongly suggest that various amphibian and piscine AMPs may play important roles in protecting fish and amphibians from pathogenic viruses...
Induction of apoptosis in frog virus 3-infected cellsV G Chinchar
Department of Microbiology, University of Mississippi Medical Center, Jackson, MS 39216, USA
Virology 306:303-12. 2003..However, it remains to be determined if virion attachment to target cells is sufficient to induce cell death, or if apoptosis is triggered directly or indirectly by one or more virion-associated proteins...
Ranaviruses (family Iridoviridae): emerging cold-blooded killersV G Chinchar
Department of Microbiology, University of Mississippi Medical Center, Jackson 39216 4505, USA
Arch Virol 147:447-70. 2002..In light of the above, it is clear that ranaviruses are no longer orphan viruses, and that they have a significant impact on diverse populations of ectothermic animals...
Inactivation of frog virus 3 and channel catfish virus by esculentin-2P and ranatuerin-2P, two antimicrobial peptides isolated from frog skinV G Chinchar
Department of Microbiology, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA
Virology 288:351-7. 2001..This is the first report linking amphibian antimicrobial peptides with protection from an amphibian viral pathogen and suggests that these compounds may play a role in maintaining amphibian health...
Identification and expression analysis of cDNAs encoding channel catfish type I interferonsScott Long
Department of Microbiology, University of Mississippi Medical Center, 2500 North State Street, Jackson, 39216, USA
Fish Shellfish Immunol 21:42-59. 2006..While it is likely that CF IFNs represent Type I IFNs, several characteristics preclude assigning these cytokines to any particular subfamily...
MHC class I genes of the channel catfish: sequence analysis and expressionA B Antao
Department of Microbiology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Immunogenetics 49:303-11. 1999..This latter finding is the first direct evidence for the cell surface association of beta2m with the MHC class I alpha chain on teleost cells and supports the notion that functional MHC class I proteins exist in teleosts...
Channel catfish reovirus (CRV) inhibits replication of channel catfish herpesvirus (CCV) by two distinct mechanisms: viral interference and induction of an anti-viral factorV G Chinchar
Department of Microbiology, University of Mississippi Medical Center, Jackson 39216, USA
Dis Aquat Organ 33:77-85. 1998....
Identification and expression analysis of interferon gamma genes in channel catfishIvanka Milev-Milovanovic
Department of Microbiology, University of Mississippi Medical Center, Jackson, MS 39216, USA
Immunogenetics 58:70-80. 2006..Collectively, these studies indicate that Siluriformes possess two evolutionarily conserved IFN-gamma genes and demonstrate that CF possess three key elements of the innate immune response: NK cells and types I and II IFN...
Expression profiles of cloned channel catfish (Ictalurus punctatus) lymphoid cell lines and mixed lymphocyte culturesS Majji
Department of Microbiology, University of Mississippi Medical Center, Jackson, MS 39216, United States
Dev Comp Immunol 33:224-34. 2009....
Genomic organization and differential expression of channel catfish MHC class I genesA B Antao
Department of Microbiology, University of Mississippi Medical Center, Jackson, MS 39216, USA
Dev Comp Immunol 25:579-95. 2001....
Transcriptome analysis of Frog virus 3, the type species of the genus Ranavirus, family IridoviridaeS Majji
Department of Microbiology, University of Mississippi Medical Ctr, 2500 North State Street, Jackson, MS 39216, USA
Virology 391:293-303. 2009....
Heterogeneity of channel catfish CTL with respect to target recognition and cytotoxic mechanisms employedH Zhou
Department of Microbiology, University of Mississippi Medical Center, Jackson, MS 39216, USA
J Immunol 167:1325-32. 2001..Consistent with the presumed use of a secretory pathway, both groups of CTL possess putative lytic granules. These results suggest that catfish CTL show heterogeneity with respect to target recognition and cytotoxic mechanisms...
Antisense approaches for elucidating ranavirus gene function in an infected fish cell lineD S Whitley
Department of Microbiology, University of Mississippi Medical Center, Jackson, MS 39216, United States
Dev Comp Immunol 35:937-48. 2011....
Identification of a cDNA encoding channel catfish interferonScott Long
Department of Microbiology, University of Mississippi Medical Center, Jackson, MS 39216, USA
Dev Comp Immunol 28:97-111. 2004..To confirm these results, recombinant CF IFN was synthesized in COS-7 cells and shown to have antiviral activity in CCO cells. Collectively, these results argue strongly that the identified catfish cDNA is an IFN homolog...
Activation of channel catfish (Ictalurus punctatus) T cells involves NFAT-like transcription factorsH Park
Department of Microbiology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Dev Comp Immunol 26:775-84. 2002..These results suggest that cytokines are involved in the activation of teleost T cells, and argue that T cell activation processes are conserved over a wide phylogenetic distance...
Cloning, sequence analysis, and expression of the major capsid protein of the iridovirus frog virus 3J Mao
Department of Microbiology, University of Mississippi Medical Center, Jackson, 39216, USA
Virology 216:431-6. 1996..These results indicate that iridoviruses possess an evolutionarily related major capsid protein and provide information useful not only in studies of viral gene expression, but also in characterizing newly isolated iridoviruses...
Molecular identification and expression analysis of tumor necrosis factor in channel catfish (Ictalurus punctatus)J Zou
School of Biological Sciences, University of Aberdeen, Aberdeen AB24 2TZ, UK
Dev Comp Immunol 27:845-58. 2003..These results demonstrate that a catfish homolog of TNFalpha has been identified, and indicate that catfish TNFalpha is expressed in catfish in a manner similar to that seen in mammals...
