Research Topics
Genomes and GenesSpecies | Alvin J ChinSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Detail Information
Publications
How insights from cardiovascular developmental biology have impacted the care of infants and children with congenital heart diseaseAlvin J Chin
Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, United States
Mech Dev 129:75-97. 2012..These three developmental biology stories illustrate how the remaining unexplained mortality and morbidity of congenital heart disease can be solved...
Heart and gut chiralities are controlled independently from initial heart position in the developing zebrafishA J Chin
Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Dev Biol 227:403-21. 2000....
Serum alkaline phosphatase reflects post-Fontan hemodynamics in childrenAlvin J Chin
Division of Cardiology, Abramson Research Center, The Children s Hospital of Philadelphia, and Department of Pediatrics, University of Pennsylvania, School of Medicine, Philadelphia, PA 19104, USA
Pediatr Cardiol 30:138-45. 2009..Serum TALP activity, an indicator of osteoblastic function particularly in pre-adolescence, may be a marker of low cardiac output after a Fontan operation...
Cloning and characterization of zebrafish tbx1Lazaros K Kochilas
Department of Pediatrics, Division of Pediatric Cardiology, Brown University Medical School, Providence, RI, USA
Gene Expr Patterns 3:645-51. 2003..This newly identified tbx1 expression pattern in cardiac regions other than the cardiac outflow tract offers a new insight into the role of the tbx1 transcription factor in cardiac development...
Maternally controlled (beta)-catenin-mediated signaling is required for organizer formation in the zebrafishC Kelly
Department of Biology, The University of Pennsylvania, Philadelphia, PA 19104, USA
Development 127:3899-911. 2000..This work demonstrates that a maternal gene controlling localization of (beta)-catenin in dorsal nuclei is necessary for dorsal yolk syncytial layer gene activity and formation of the organizer in the zebrafish...
Zebrafish hhex regulates liver development and digestive organ chiralityK N Wallace
Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Genesis 30:141-3. 2001
Analysis of Cx43alpha1 promoter function in the developing zebrafish embryoB Chatterjee
Biology Dept, University of Pennsylvania, Philadelphia, USA
Cell Commun Adhes 8:289-92. 2001..Overall these studies suggest that the sequence motifs and transcriptional regulation involved in the targeting Cx43alpha1 expression to neural crest cells are evolutionarily conserved in zebrafish and mouse embryos...
Using health-related quality of life measures to predict cardiac function in survivors exposed to anthracyclinesJill P Ginsberg
Department of Pediatrics, Center for Outcomes Research, The Children's Hospital of Philadelphia, 3535 Market St, Suite 1029, Philadelphia, PA 19104, USA
J Clin Oncol 22:3149-55. 2004..Patient history appears to be no substitute for cardiac testing in this cohort...
T-box genes and cardiac developmentKenneth Ryan
Children s Hospital of Philadelphia, University of Pennsylvania School of Medicine, Joseph Stokes Jr Research Institute, Division of Cardiology, Abramson Research Center, Philadelphia, Pennsylvania, USA
Birth Defects Res C Embryo Today 69:25-37. 2003..Drosophila melanogaster has eight T-box genes, whereas Caenorhabditis elegans has 22. Mammals appear to have at least 18 T-box genes, comprising five subfamilies...
Heart and neural tube defects in transgenic mice overexpressing the Cx43 gap junction geneJ L Ewart
Department of Biology, University of Pennsylvania, Philadelphia 19104, USA
Development 124:1281-92. 1997..As such, the CMV43 mouse may represent a powerful new model system for examining the role of extracardiac cell populations in cardiac morphogenesis and other developmental processes...
