Martin K Childers

Summary

Affiliation: University of Missouri
Country: USA

Publications

  1. ncbi request reprint Low-dose cyclobenzaprine versus combination therapy with ibuprofen for acute neck or back pain with muscle spasm: a randomized trial
    Martin K Childers
    Physical Medicine and Rehabilitation, University of Missouri Columbia, Columbia, MO 65212, USA
    Curr Med Res Opin 21:1485-93. 2005
  2. ncbi request reprint Eccentric contraction injury in dystrophic canine muscle
    Martin K Childers
    Departments of Physical Medicine and Rehabilitation, College of Veterinary Medicine, University of Missouri Columbia, One Hospital Drive, Columbia, MO 65212, USA
    Arch Phys Med Rehabil 83:1572-8. 2002
  3. ncbi request reprint The importance of electromyographic guidance and electrical stimulation for injection of botulinum toxin
    Martin K Childers
    Department of Physical Medicine, School of Medicine, University of Missouri Columbia, DCO 46 00, One Hospital Drive, Columbia, MO 65212, USA
    Phys Med Rehabil Clin N Am 14:781-92. 2003
  4. ncbi request reprint Regulatory light chain phosphorylation increases eccentric contraction-induced injury in skinned fast-twitch fibers
    Martin K Childers
    Department of Physical Medicine and Rehabilitation, DCO 46 00, One Hospital Drive, University of Missouri Columbia, Columbia, Missouri 65212, USA
    Muscle Nerve 29:313-7. 2004
  5. ncbi request reprint Dose-dependent response to intramuscular botulinum toxin type A for upper-limb spasticity in patients after a stroke
    Martin K Childers
    Dept of Physical Medicine and Rehabilitation, University of Missouri at Columbia, One Hospital Drive, DCO 46 00, Columbia, MO 65212, USA
    Arch Phys Med Rehabil 85:1063-9. 2004
  6. ncbi request reprint Skinned single fibers from normal and dystrophin-deficient dogs incur comparable stretch-induced force deficits
    Martin K Childers
    Department of Physical Medicine and Rehabilitation, School of Medicine, University of Missouri Columbia, DCO 46 00, One Hospital Drive, Columbia, Missouri 65212, USA
    Muscle Nerve 31:768-71. 2005
  7. doi request reprint Testosterone replacement therapy and motor function in men with spinal cord injury: a retrospective analysis
    Mary J Clark
    Department of Health Psychology, University of Missouri Columbia, Columbia, Missouri, USA
    Am J Phys Med Rehabil 87:281-4. 2008
  8. ncbi request reprint Effects of prednisone in canine muscular dystrophy
    Jocelyn M K Liu
    Dalton Cardiovascular Research Center, University of Missouri Columbia, Columbia, Missouri, USA
    Muscle Nerve 30:767-73. 2004
  9. doi request reprint Golden retriever muscular dystrophy (GRMD): Developing and maintaining a colony and physiological functional measurements
    Joe N Kornegay
    Department of Pathology and Laboratory Medicine and The Gene Therapy Center, School of Medicine, University of North Carolina Chapel Hill, Chapel Hill, NC, USA
    Methods Mol Biol 709:105-23. 2011
  10. ncbi request reprint Stretch-induced force deficits in murine extensor digitorum longus muscles after cardiotoxin injection
    Chad Markert
    Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, USA
    Muscle Nerve 34:485-8. 2006

Research Grants

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Low-dose cyclobenzaprine versus combination therapy with ibuprofen for acute neck or back pain with muscle spasm: a randomized trial
    Martin K Childers
    Physical Medicine and Rehabilitation, University of Missouri Columbia, Columbia, MO 65212, USA
    Curr Med Res Opin 21:1485-93. 2005
    ....
  2. ncbi request reprint Eccentric contraction injury in dystrophic canine muscle
    Martin K Childers
    Departments of Physical Medicine and Rehabilitation, College of Veterinary Medicine, University of Missouri Columbia, One Hospital Drive, Columbia, MO 65212, USA
    Arch Phys Med Rehabil 83:1572-8. 2002
    ..To test the hypothesis that eccentric contractions induce greater injury in dystrophic compared with normal canine muscle...
  3. ncbi request reprint The importance of electromyographic guidance and electrical stimulation for injection of botulinum toxin
    Martin K Childers
    Department of Physical Medicine, School of Medicine, University of Missouri Columbia, DCO 46 00, One Hospital Drive, Columbia, MO 65212, USA
    Phys Med Rehabil Clin N Am 14:781-92. 2003
    ..Questions remain about the preferred administration of botulinum toxin for these conditions. Future clinical research is necessary to show clearly functional benefit of any particular injection localization method...
  4. ncbi request reprint Regulatory light chain phosphorylation increases eccentric contraction-induced injury in skinned fast-twitch fibers
    Martin K Childers
    Department of Physical Medicine and Rehabilitation, DCO 46 00, One Hospital Drive, University of Missouri Columbia, Columbia, Missouri 65212, USA
    Muscle Nerve 29:313-7. 2004
    ..5) activation from 26 +/- 9.8 to 35 +/- 9.6%. We conclude that RLC phosphorylation increases force deficits following eccentric contractions, perhaps by increasing the number of force-generating cross-bridges...
  5. ncbi request reprint Dose-dependent response to intramuscular botulinum toxin type A for upper-limb spasticity in patients after a stroke
    Martin K Childers
    Dept of Physical Medicine and Rehabilitation, University of Missouri at Columbia, One Hospital Drive, DCO 46 00, Columbia, MO 65212, USA
    Arch Phys Med Rehabil 85:1063-9. 2004
    ..To test the hypothesis that intramuscular (IM) botulinum toxin type A (BTX) reduces excessive muscle tone in a dose-dependent manner in the elbow, wrist, and fingers of patients who experience spasticity after a stroke...
  6. ncbi request reprint Skinned single fibers from normal and dystrophin-deficient dogs incur comparable stretch-induced force deficits
    Martin K Childers
    Department of Physical Medicine and Rehabilitation, School of Medicine, University of Missouri Columbia, DCO 46 00, One Hospital Drive, Columbia, Missouri 65212, USA
    Muscle Nerve 31:768-71. 2005
    ....
  7. doi request reprint Testosterone replacement therapy and motor function in men with spinal cord injury: a retrospective analysis
    Mary J Clark
    Department of Health Psychology, University of Missouri Columbia, Columbia, Missouri, USA
    Am J Phys Med Rehabil 87:281-4. 2008
    ..To evaluate motor function in men with spinal cord injury (SCI) given testosterone replacement therapy (TRT)...
  8. ncbi request reprint Effects of prednisone in canine muscular dystrophy
    Jocelyn M K Liu
    Dalton Cardiovascular Research Center, University of Missouri Columbia, Columbia, Missouri, USA
    Muscle Nerve 30:767-73. 2004
    ..Thus, functional data indicate benefit but histopathologic changes following prednisone treatment in GRMD suggest possible deleterious consequences...
  9. doi request reprint Golden retriever muscular dystrophy (GRMD): Developing and maintaining a colony and physiological functional measurements
    Joe N Kornegay
    Department of Pathology and Laboratory Medicine and The Gene Therapy Center, School of Medicine, University of North Carolina Chapel Hill, Chapel Hill, NC, USA
    Methods Mol Biol 709:105-23. 2011
    ..Key challenges in colony development (breeding, neonatal death, and the risk of inbreeding) and representative functional measurements (tibiotarsal joint angle and torque force; and eccentric contraction decrement) are discussed...
  10. ncbi request reprint Stretch-induced force deficits in murine extensor digitorum longus muscles after cardiotoxin injection
    Chad Markert
    Department of Biomedical Sciences, College of Veterinary Medicine, University of Missouri, Columbia, Missouri, USA
    Muscle Nerve 34:485-8. 2006
    ..001) on day 7. We speculate that increased contraction-induced damage in 7-day CTX-injected muscles results from changes in myofilament overlap that occurs during early regeneration...
  11. doi request reprint The paradox of muscle hypertrophy in muscular dystrophy
    Joe N Kornegay
    Department of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina Chapel Hill, Chapel Hill, NC 27599, USA
    Phys Med Rehabil Clin N Am 23:149-72, xii. 2012
    ..Muscle hypertrophy can exaggerate postural instability and joint contractures. Deleterious consequences of muscle hypertrophy should be considered when developing treatments for muscular dystrophy...
  12. ncbi request reprint Effects of intra-articular botulinum toxin type A in an equine model of acute synovitis: a pilot study
    Tracy Depuy
    From the Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri Columbia, Columbia, Missouri, USA
    Am J Phys Med Rehabil 86:777-83. 2007
    ..To test the hypothesis that botulinum toxin type A (BoNT-A) can attenuate lameness associated with acute synovitis in an equine model...
  13. ncbi request reprint Targeting the neuromuscular junction in skeletal muscles
    Martin K Childers
    Department of Physical Medicine and Rehabilitation, School of Medicine, University of Missouri Columbia, Columbia, Missouri 65212, USA
    Am J Phys Med Rehabil 83:S38-44. 2004
    ..In this article, a rationale is presented for motor endplate targeting within specific limb muscles with respect to botulinum neurotoxin therapy...
  14. ncbi request reprint Botulinum toxin type A use in piriformis muscle syndrome: a pilot study
    Martin K Childers
    Department of Physical Medicine and Rehabilitation, University of Missouri Columbia Hospital, 65212, USA
    Am J Phys Med Rehabil 81:751-9. 2002
    ..This study was undertaken to test the hypothesis that intramuscular botulinum toxin type A decreases chronic pain attributed to piriformis muscle syndrome to a greater extent than a similar injection with vehicle (saline) alone...
  15. pmc Mesenchymal stem cells: emerging therapy for Duchenne muscular dystrophy
    Chad D Markert
    Department of Neurology, School of Medicine, and Wake Forest Institute for Regenerative Medicine, Wake Forest University Health Sciences, Winston Salem, NC, USA
    PM R 1:547-59. 2009
    ..In this review, the authors explore the potential for mesenchymal stem cell therapy in the emerging field of regenerative medicine with a focus on treatment for Duchenne muscular dystrophy...
  16. ncbi request reprint Testosterone levels among men with spinal cord injury admitted to inpatient rehabilitation
    Laura H Schopp
    Department of Health Psychology, University of Missouri Columbia, Columbia, Missouri 65212, USA
    Am J Phys Med Rehabil 85:678-84; quiz 685-7. 2006
    ..The present study documented the prevalence of low testosterone among men with SCI...
  17. ncbi request reprint Myostatin expression in muscular dystrophies and mitochondrial encephalomyopathies
    Chad Markert
    Pediatr Neurol 35:300; author reply 300. 2006

Research Grants2

  1. MUSCLE RESPONSE TO STRESS IN CANINE MUSCULAR DYSTROPHY
    MARTIN CHILDERS; Fiscal Year: 2002
    ..It is anticipated that findings will improve the understanding of how dystrophic muscle responds to physical stress resulting in improved treatment for patients with Duchenne muscular dystrophy. ..
  2. Leupeptin in a Canine Model of Duchenne Muscular Dystrophy
    MARTIN CHILDERS; Fiscal Year: 2006
    ..Specific Aim #4b: Compare lean body muscle mass and calpain activity between leupeptin and placebo-treated GRMD dogs. ..