D C Chhieng

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi Fine-needle aspiration of spindle cell and mesenchymal lesions of the salivary glands
    D C Chhieng
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Diagn Cytopathol 23:253-9. 2000
  2. ncbi Clinical implications of atypical glandular cells of undetermined significance, favor endometrial origin
    D C Chhieng
    Department of Pathology, University of Alabama at Birmingham, 35249 6823, USA
    Cancer 93:351-6. 2001
  3. ncbi High-risk HPV DNA detection rate in patients with atypical squamous cells and its relationship to the atypical squamous cell: squamous intraepithelial lesion ratio
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham 35249 6823, USA
    Acta Cytol 50:291-4. 2006
  4. ncbi Cytology of primary central nervous system neoplasms in cerebrospinal fluid specimens
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, Alabama
    Diagn Cytopathol 26:209-12. 2002
  5. ncbi Interobserver variability: comparison between liquid-based and conventional preparations in gynecologic cytology
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249 6823, USA
    Cancer 96:67-73. 2002
  6. ncbi Atypical glandular cells
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, 619 19th Street South, KB 627, Birmingham, AL 35249 6823, USA
    Clin Lab Med 23:633-57. 2003
  7. doi Cytology of bronchial associated lymphoid tissue lymphoma
    David C Chhieng
    Department of Pathology University of Alabama Birmingham, Alabama 35249 6823, USA
    Diagn Cytopathol 36:723-8. 2008
  8. ncbi Bethesda 2001. Impact on the reporting of gynecologic cytology
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, 619 19 St S, KB 627, Birmingham, AL 35249 6823, USA
    Acta Cytol 48:355-62. 2004
  9. ncbi MUC1 and MUC2 expression in pancreatic ductal carcinoma obtained by fine-needle aspiration
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249 6823, USA
    Cancer 99:365-71. 2003
  10. ncbi Microvessel density and vascular endothelial growth factor expression in infiltrating lobular mammary carcinoma
    David C Chhieng
    Department of Pathology and Biostatistics Unit, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Breast J 9:200-7. 2003

Collaborators

Detail Information

Publications86

  1. ncbi Fine-needle aspiration of spindle cell and mesenchymal lesions of the salivary glands
    D C Chhieng
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Diagn Cytopathol 23:253-9. 2000
    ..A specific diagnosis can be rendered in the majority of cases by correlating clinical and cytologic findings...
  2. ncbi Clinical implications of atypical glandular cells of undetermined significance, favor endometrial origin
    D C Chhieng
    Department of Pathology, University of Alabama at Birmingham, 35249 6823, USA
    Cancer 93:351-6. 2001
    ..This study was undertaken to determine the clinical significance of atypical glandular cells of undetermined significance that favor an endometrial origin (AGUS-EM)...
  3. ncbi High-risk HPV DNA detection rate in patients with atypical squamous cells and its relationship to the atypical squamous cell: squamous intraepithelial lesion ratio
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham 35249 6823, USA
    Acta Cytol 50:291-4. 2006
    ..To determine if there is any relationship between the atypical squamous cell (ASC):squamous intraepithelial lesion (SIL) ratio and high-risk HPV DNA detection rate...
  4. ncbi Cytology of primary central nervous system neoplasms in cerebrospinal fluid specimens
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, Alabama
    Diagn Cytopathol 26:209-12. 2002
    ..The use of immunocytochemistry is helpful in confirming the cytologic impression in some cases...
  5. ncbi Interobserver variability: comparison between liquid-based and conventional preparations in gynecologic cytology
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249 6823, USA
    Cancer 96:67-73. 2002
    ..Little is known about the interobserver variability of reporting gynecologic cytology results using the TP preparation and its comparison with results obtained using the conventional method...
  6. ncbi Atypical glandular cells
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, 619 19th Street South, KB 627, Birmingham, AL 35249 6823, USA
    Clin Lab Med 23:633-57. 2003
    ....
  7. doi Cytology of bronchial associated lymphoid tissue lymphoma
    David C Chhieng
    Department of Pathology University of Alabama Birmingham, Alabama 35249 6823, USA
    Diagn Cytopathol 36:723-8. 2008
    ..A diagnosis of bronchial associated lymphoid tissue (BALT) lymphoma was established. The patient was treated with rituximab and was disease free 2 years after initial diagnosis...
  8. ncbi Bethesda 2001. Impact on the reporting of gynecologic cytology
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, 619 19 St S, KB 627, Birmingham, AL 35249 6823, USA
    Acta Cytol 48:355-62. 2004
    ..To examine the impact of implementing Bethesda 2001 in one laboratory...
  9. ncbi MUC1 and MUC2 expression in pancreatic ductal carcinoma obtained by fine-needle aspiration
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249 6823, USA
    Cancer 99:365-71. 2003
    ....
  10. ncbi Microvessel density and vascular endothelial growth factor expression in infiltrating lobular mammary carcinoma
    David C Chhieng
    Department of Pathology and Biostatistics Unit, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Breast J 9:200-7. 2003
    ..The absence of a statistically significant positive correlation between MVD and VEGF expression suggests that other factors may play a more important role in the angiogenesis of ILC...
  11. ncbi Malignant pleural effusions due to small-cell lung carcinoma: a cytologic and immunocytochemical study
    D C Chhieng
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249 6823, USA
    Diagn Cytopathol 25:356-60. 2001
    ..The cytology of SCLC is characteristic. The use of immunocytochemistry, particularly with antibodies to chromogranin A, TTF-1, and CK 20, aids in the differential diagnosis...
  12. ncbi Clinical significance of atypical glandular cells of undetermined significance in postmenopausal women
    D C Chhieng
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249 6823, USA
    Cancer 93:1-7. 2001
    ..Therefore, it is important to determine the clinical implication of a diagnosis of atypical glandular cells of undetermined significance (AGUS) in postmenopausal patients...
  13. ncbi Cytology and immunophenotyping of low- and intermediate-grade B-cell non-Hodgkin's lymphomas with a predominant small-cell component: a study of 56 cases
    D C Chhieng
    Department of Pathology, KB 526, University of Alabama at Birmingham, 619 19 St S, Birmingham, AL 35249 6823, USA
    Diagn Cytopathol 24:90-7. 2001
    ..We conclude that cytology, when used in conjunction with immunophenotyping, can accurately diagnose and in most instances subclassify low- and intermediate-grade B-cell non-Hodgkin's lymphoma with a predominant small-cell population...
  14. ncbi Fine-needle aspiration cytology of Hodgkin disease: a study of 89 cases with emphasis on false-negative cases
    D C Chhieng
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249 6823, USA
    Cancer 93:52-9. 2001
    ..In this study, the authors examined the factors contributing to a false-negative diagnosis of HD...
  15. ncbi Significance of AGUS Pap smears in pregnant and postpartum women
    D C Chhieng
    Department of Pathology, New York University Medical Center, New York, New York, USA
    Acta Cytol 45:294-9. 2001
    ..To study the clinical significance of atypical glandular cells of undertermined significance (AGUS) in pregnant and postpartum women...
  16. ncbi Use of thyroid transcription factor 1, PE-10, and cytokeratins 7 and 20 in discriminating between primary lung carcinomas and metastatic lesions in fine-needle aspiration biopsy specimens
    D C Chhieng
    Department of Pathology, University of Alabama at Birmingham, 35249 6823, USA
    Cancer 93:330-6. 2001
    ..The combination of cytokeratin 7 (CK7) and cytokeratin 20 (CK20) immunoprofiling has been helpful in the identification of the primary site of origin of lung tumors...
  17. ncbi Endoscopic ultrasound-guided fine-needle aspiration biopsy: a study of 103 cases
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249 6823, USA
    Cancer 96:232-9. 2002
    ..To better evaluate the clinical utility and efficiency of EUS-FNAB, a retrospective analysis of the first 103 EUS-FNABs performed at our institute was undertaken...
  18. ncbi Use of E-cadherin and CD44 aids in the differentiation between reactive mesothelial cells and carcinoma cells in pelvic washings
    D C Chhieng
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Cancer 90:299-306. 2000
    ..The differentiation between reactive mesothelial cells and carcinoma cells can be a diagnostic challenge based on morphology alone. The expression of some cell adhesion molecules may be helpful in the differential diagnosis...
  19. ncbi Cumulative sum procedure in evaluation of EUS-guided FNA cytology: the learning curve and diagnostic performance beyond sensitivity and specificity
    I A Eltoum
    Division of Anatomic Pathology, Department of Pathology, the Uniersity of Alabama at Birmingham, Birmingham, AL 35233, USA
    Cytopathology 18:143-50. 2007
    ..non-diagnostic rate defined as technical failures, unsatisfactory specimens and atypical and suspicious diagnoses? (ii) Over time, how will EUS-FNA maintain acceptable diagnostic errors (false-positives plus false-negative diagnosis)?..
  20. ncbi Variation in the incidence of AGUS between different patient populations
    D C Chhieng
    Department of Pathology, New York University Medical Center, New York, New York, USA
    Acta Cytol 45:287-93. 2001
    ..CONCLUSION: The AGUS rate in our laboratory was low and within the range (0.17-1.83%) reported in the literature. The AGUS rate varies with different patient populations, particularly with the incidence of SIL and age distribution...
  21. ncbi Transgastric endoscopic ultrasound-guided fine-needle aspiration biopsy and flow cytometry of suspected lymphoma of the spleen
    M A Eloubeidi
    Division of Gastroenterology and Hepatology, University of Alabama at Birmingham, Birmingham, Alabama 35294 0007, USA
    Endoscopy 38:617-20. 2006
    ..We report our experience with transgastric EUS-FNA and flow cytometry in the investigation of patients with suspected lymphoma of the spleen...
  22. doi Immunohistochemical detection of EGFR, p185(erbB-2), Bcl-2 and p53 in breast carcinomas in pre-menopausal and post-menopausal women
    Li Talley
    Biostatistics Unit of the Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Biotech Histochem 83:5-14. 2008
    ..In addition, there were differences in the prognostic effectiveness of these biomarkers in pre- vs. post-menopausal women...
  23. ncbi Use of a panel of markers in the differential diagnosis of adenocarcinoma and reactive mesothelial cells in fluid cytology
    E C Ko
    Department of Pathology, University of Alabama at Birmingham, 35249-6823, USA
    Am J Clin Pathol 116:709-15. 2001
    ..The profile of positive staining with at least one of the adenocarcinoma markers and negative calretinin staining is highly specific and sensitive for identifying adenocarcinoma in fluid cytology...
  24. ncbi Transthoracic fine-needle aspiration biopsy of pulmonary spindle cell and mesenchymal lesions: a study of 61 cases
    P Hummel
    Department of Pathology, New York University Medical Center, New York, New York, USA
    Cancer 93:187-98. 2001
    ..By correlating clinical and radiologic data, cytologic findings, and ancillary studies, a high diagnostic accuracy rate can be achieved with FNA...
  25. ncbi Yield of endoscopic ultrasound-guided fine-needle aspiration biopsy in patients with suspected pancreatic carcinoma
    Mohamad A Eloubeidi
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Cancer 99:285-92. 2003
    ....
  26. ncbi Microphthalmia transcription factor: a sensitive and specific marker for malignant melanoma in cytologic specimens
    C C Dorvault
    Department of Pathology, University of Alabama at Birmingham, 35249 6823, USA
    Cancer 93:337-43. 2001
    ..Microphthalmia transcription factor (Mitf) is a nuclear transcription factor critical for the development and survival of melanocytes and has been shown as a sensitive and specific marker for melanoma in histologic specimens...
  27. doi Diagnostic utility of mammaglobin and GCDFP-15 in the identification of metastatic breast carcinoma in fluid specimens
    Z Yan
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Diagn Cytopathol 37:475-8. 2009
    ..05). Both MGB1 and GCDFP-15 are specific markers for metastatic breast carcinomas in cell block fluid specimens (88 vs. 96%). However, MGB1 is more sensitive than GCDFP-15 as a marker for metastatic breast carcinoma (87 vs. 46%)...
  28. ncbi Diagnosis of gastrointestinal tract lesions by endoscopic ultrasound-guided fine-needle aspiration biopsy
    Martin R Vander Noot
    Department of Pathology, University of Alabama Birmingham, Birmingham, Alabama, USA
    Cancer 102:157-63. 2004
    ..The objective of the current study was to determine the diagnostic utility of EUS-FNA in evaluating intramural and extramural GI tract lesions...
  29. ncbi Recurrent metastatic Klatskin's carcinoid tumor to celiac lymph nodes in a teenager: diagnosis by endoscopic ultrasound-guided fine needle aspiration biopsy with immunocytochemical correlation
    Mohamad A Eloubeidi
    Division of Gastroenterology and Hepatology, Department of Pathology, The University of Alabama at Birmingham, 1530 3rd Avenue South ZRB 636, Birmingham, Alabama 35294 0007, USA
    Dig Dis Sci 48:2301-5. 2003
  30. ncbi Endoscopic ultrasound-guided fine-needle aspiration. A cytopathologist's perspective
    Nirag C Jhala
    Department of Pathology, University of Alabama, Birmingham, USA
    Am J Clin Pathol 120:351-67. 2003
    ..On-site assessment permits a highly accurate preliminary diagnosis of malignancy for samples obtained by EUS-FNA and provides an opportunity to increase the diagnostic yield of samples...
  31. ncbi Basaloid tumors of the salivary glands
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, AL 35249 6823, USA
    Ann Diagn Pathol 6:364-72. 2002
    ..However, in limited biopsies and particularly in cytologic samples, the evaluation can be quite challenging. A systematic approach aided by immunohistochemistry is essential to arrive at an accurate diagnosis...
  32. ncbi Fine-needle aspiration biopsy of peripheral T-cell lymphomas. A cytologic and immunophenotypic study of 33 cases
    J L Yao
    Department of Pathology, New York University Medical Center, New York, New York, USA
    Cancer 93:151-9. 2001
    ..CONCLUSIONS: Peripheral T-cell lymphoma is a heterogeneous group of lesions with diverse cytomorphology. Cytologic analysis and immunophenotyping is an accurate method of diagnosing peripheral T-cell lymphoma...
  33. ncbi Prediction of aggressiveness of gastrointestinal stromal tumours based on immunostaining with bcl-2, Ki-67 and p53
    R S Meara
    Department of Pathology, University of Alabama, Birmingham, AL 35249 6823, USA
    Cytopathology 18:283-9. 2007
    ..The objective of the current study was to determine if expression of bcl-2, Ki-67 and p53 correlated with the outcome of GISTs based on cytological material...
  34. doi Fine-needle aspiration cytology of pulmonary mucinous cystadenocarcinoma
    David C Chhieng
    Department of Pathology, University of Alabama, Birmingham, Alabama 35249 6823, USA
    Diagn Cytopathol 36:581-5. 2008
    ....
  35. ncbi Significance and possible causes of false-negative results of reflex human Papillomavirus infection testing
    Isam A Eltoum
    Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL 35233, USA
    Cancer 111:154-9. 2007
    ..The objective of this study was to assess the rate and possible reasons for false-negative (FN) reflex human papillomavirus (HPV)-DNA tests...
  36. ncbi Endoscopic ultrasound-guided fine-needle aspiration biopsy of the adrenal glands: analysis of 24 patients
    Nirag C Jhala
    Department of Pathology, University of Alabama Birmingham, Birmingham, Alabama 35249, USA
    Cancer 102:308-14. 2004
    ..Thus, EUS-FNA biopsy offers a novel opportunity to evaluate and obtain cytology samples from adrenal gland lesions. The objective of the current study was to determine the utility of EUS-FNA in the diagnosis of adrenal lesions...
  37. ncbi Reflex human papilloma virus infection testing detects the same proportion of cervical intraepithelial neoplasia grade 2-3 in young versus elderly women
    Isam A Eltoum
    Department of Pathology, The University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Cancer 105:194-8. 2005
    ..Because age is an important determinant of the incidence of both ASCUS and HPV infection, the current study was conducted to determine the impact of age on reflex HPV infection test performance...
  38. ncbi Clinical significance of unsatisfactory conventional pap smears owing to inadequate squamous cellularity defined by the Bethesda 2001 criterion
    Amy L Adams
    Department of Pathology, University of Alabama at Birmingham, 35249 6823, USA
    Am J Clin Pathol 123:738-43. 2005
    ....
  39. ncbi Fine needle aspiration biopsy of the islet cell tumor of pancreas: a comparison between computerized axial tomography and endoscopic ultrasound-guided fine needle aspiration biopsy
    Darshana Jhala
    Division of Anatomic Pathology, Department of Pathology, University of Alabama at Birmingham, 35249, USA
    Ann Diagn Pathol 6:106-12. 2002
    ..EUS-FNA is superior to CT- FNA for obtaining cells for the diagnosis of ICT. Detection of mitoses and or necrosis from patients with ICT should initiate a search for metastasis...
  40. ncbi Endoscopic ultrasound-guided fine-needle aspiration biopsy: a powerful tool to obtain samples from small lesions
    Nirag C Jhala
    Division of Anatomic Pathology, Department of Pathology, The University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Cancer 102:239-46. 2004
    ..The objective of the current study was to determine whether small lesions (< or = 25 mm) affected the specimen adequacy and the diagnostic accuracy for lesions aspirated under EUS guidance...
  41. ncbi Cytology of myoepithelial carcinoma of the salivary gland
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, Birmingham Alabama 35249 6823, USA
    Cancer 96:32-6. 2002
    ..Myoepithelial carcinoma, also know as malignant myoepithelioma, is rare in the salivary gland, and its cytologic features have rarely been reported...
  42. ncbi Fine-needle aspiration biopsy of hepatic lesions: computerized tomographic-guided versus endoscopic ultrasound-guided FNA
    D Ralph Crowe
    Division of Anatomic Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Cancer 108:180-5. 2006
    ....
  43. ncbi Probabilistic reporting of EUS-FNA cytology: Toward improved communication and better clinical decisions
    Isam A Eltoum
    Division of Anatomic Pathology, Department of Pathology, The University of Alabama at Birmingham, Birmingham, Alabama, USA
    Cancer 108:93-101. 2006
    ..The goal was to aid endoscopists in making appropriate clinical decisions based on both quantitative and qualitative approaches...
  44. doi HPV detection rate in discordant Pap tests between cytotechnologists and pathologists
    David C Chhieng
    Department of Pathology, Yale University, New Haven, CT 06520 8023, USA
    Diagn Cytopathol 37:320-3. 2009
    ....
  45. ncbi Providing on-site diagnosis of malignancy on endoscopic-ultrasound-guided fine-needle aspirates: should it be done?
    Nirag C Jhala
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Ann Diagn Pathol 11:176-81. 2007
    ..Here we report our experience of prospectively providing on-site diagnosis on 485 endoscopic ultrasound fine-needle aspirate samples...
  46. doi The effect of neoadjuvant chemotherapy on histologic grade, hormone receptor status, and HER2/neu status in breast carcinoma
    Amy L Adams
    Department of Pathology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Breast J 14:141-6. 2008
    ..No significant changes were noted for the degree of tubule formation, nuclear pleomorphism, overall Bloom-Richardson score, and hormone receptor status. However, small sample size may be a limitation of these results...
  47. ncbi Glandular cell atypia on Papanicolaou smears: interobserver variability in the diagnosis and prediction of cell of origin
    Aylin Simsir
    Division of Cytopathology, Department of Pathology, New York University Medical Center, New York, New York 10016, USA
    Cancer 99:323-30. 2003
    ..The aim of the current study was to investigate whether a variety of benign to neoplastic glandular lesions can be reliably classified on Pap smear with regard to diagnosis and cell of origin...
  48. ncbi Endoscopic ultrasound-guided fine needle aspiration biopsy of patients with suspected pancreatic cancer: diagnostic accuracy and acute and 30-day complications
    Mohamad A Eloubeidi
    Department of Medicine, Division of Gastroenterology and Hepatology, University of Alabama at Birmingham, 1530 3rd Avenue S, ZRB 636, Birmingham, AL 35294 0007, USA
    Am J Gastroenterol 98:2663-8. 2003
    ....
  49. ncbi Does using a higher cutoff for the percentage of positive cells improve the specificity of HER-2 immunohistochemical analysis in breast carcinoma?
    Omar Hameed
    Department of Pathology, University of Alabama School of Medicine, Birmingham 35294 6823, USA
    Am J Clin Pathol 128:825-9. 2007
    ..These findings seem to somehow support the recently proposed American Society of Clinical Oncology/College of American Pathologists guideline recommendations for HER-2 testing; nevertheless further studies are suggested...
  50. ncbi Fine-needle aspiration biopsy of nonteratomatous germ cell tumors of the mediastinum
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, USA
    Am J Clin Pathol 118:418-24. 2002
    ..Our findings demonstrate that a diagnosis of mediastinal GCT, primary or secondary, can be established with a high degree of accuracy on the basis of FNAB. Immunocytochemical analysis helps confirm the diagnosis...
  51. ncbi Endoscopic ultrasound-guided fine needle aspiration is useful for nodal staging in patients with pleural mesothelioma
    Sarah M Bean
    Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA
    Diagn Cytopathol 36:32-7. 2008
    ..No complications were observed. EUS-FNA is a safe N2 node staging technique in patients with mesothelioma. A positive N2 lymph node by EUS-FNA may be a contraindication to definitive surgery in patients with malignant mesothelioma...
  52. ncbi Cytology and surgical pathology of pleural cavities
    Claudia Y Castro
    Immunohistochemistry Laboratory, Department of Pathology, University of Texas, Galveston, TX, USA
    Adv Exp Med Biol 563:55-69. 2005
  53. ncbi Endoscopic ultrasound-guided fine needle aspiration biopsy of suspected cholangiocarcinoma
    Mohamad A Eloubeidi
    Departments of Gastroenterology and Hepatology, University of Alabama at Birmingham, Alabama 35294 0007, USA
    Clin Gastroenterol Hepatol 2:209-13. 2004
    ..The purpose of this study was to evaluate the yield of EUS-FNA and its impact on patient management for patients with suspected cholangiocarcinoma...
  54. ncbi Diagnosis of deep-seated lymphoma and leukemia by endoscopic ultrasound-guided fine-needle aspiration biopsy
    Judith L Pugh
    Department of Pathology, University of Alabama at Birmingham, 619 19th Street South, Birmingham, AL 35233, USA
    Am J Clin Pathol 125:703-9. 2006
    ..One case of hairy cell leukemia was diagnosed. EUS-FNAB is a minimally invasive, cost-effective, and useful tool for the primary diagnosis or staging of deep-seated lymphomas...
  55. ncbi Interobserver variability in assessing adequacy of the squamous component in conventional cervicovaginal smears
    Matthew V Sheffield
    Dept of Pathology, University of Alabama at Birmingham, 619 19th St S, KB 627, Birmingham, AL 35249 6823, USA
    Am J Clin Pathol 119:367-73. 2003
    ....
  56. ncbi Immunohistochemical expression of p16 and Ki-67 correlates with degree of anal intraepithelial neoplasia
    Sarah M Bean
    Department of Pathology, Duke University, Durham, NC, USA
    Am J Surg Pathol 31:555-61. 2007
    ..Both p16 and Ki-67 are reliable markers for diagnosing high-grade AIN...
  57. ncbi Diagnosis of gastrointestinal stromal tumor by endoscopic ultrasound-guided fine needle aspiration biopsy--a potential pitfall
    Kai Fu
    Department of Pathology, The University of Alabama at Birmingham, AL 35233, USA
    Ann Diagn Pathol 6:294-301. 2002
    ..It exemplified the importance of considering GIST in the differential diagnosis of gastrointestinal lesions and also demonstrated the potential pitfalls of EUS-FNA evaluation of submucosal lesions in the gastrointestinal tract...
  58. ncbi Comparison of ThinPrep and conventional preparations in pancreatic fine-needle aspiration biopsy
    Regina de Luna
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
    Diagn Cytopathol 30:71-6. 2004
    ..Therefore, the current morphologic criteria may need modification for ThinPrep preparation in pancreatic FNA...
  59. ncbi Negative colposcopic biopsy after positive human papilloma virus (HPV) DNA testing: false-positive HPV results or false-negative histologic findings?
    Amy L Adams
    Department of Pathology, University of Alabama at Birmingham, USA
    Am J Clin Pathol 125:413-8. 2006
    ..Additional levels should be obtained for discrepant results. Close follow-up is crucial when the initial biopsy result is negative because a small number of patients will have squamous abnormalities in subsequent studies...
  60. ncbi Intratumor heterogeneity of biomarker expression in breast carcinomas
    D C Chhieng
    Department of Anatomy, University of Alabama at Birmingham, 35294 6823, USA
    Biotech Histochem 79:25-36. 2004
    ..Minor regional variations were observed for EGFR and p53 in IDC. Similarly, no significant regional variation in the expression of markers was observed in DCIS except for PCNA...
  61. ncbi Endoscopic ultrasound-guided FNA biopsy of bile duct and gallbladder: analysis of 53 cases
    R S Meara
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35249, USA
    Cytopathology 17:42-9. 2006
    ..This study investigates the role of EUS-FNA in the diagnosis of clinically suspected biliary tree and gallbladder malignancies in a large patient series...
  62. ncbi Cytology and surgical pathology of neoplasms of the lung
    Claudia Y Castro
    Immunohistochemistry Laboratory, Department of Pathology, University of Texas, Galveston, TX, USA
    Adv Exp Med Biol 563:70-90. 2005
  63. doi Fine-needle aspiration biopsy of recurrent oncocytic carcinoma of parotid gland
    Megan L Katz-Selbst
    Department of Pathology, Yale University, New Haven, Connecticut 06520 8023, USA
    Diagn Cytopathol 37:849-52. 2009
    ..The cytologic differential diagnosis should include other primary salivary gland neoplasms and metastatic disease...
  64. ncbi Cytologic grade independently predicts survival of patients with pancreatic adenocarcinoma
    Isam A Eltoum
    Department of Pathology, Division of Anatomic Pathology, University of Alabama at Birmingham, AL, USA
    Am J Clin Pathol 124:697-707. 2005
    ..We devised a grading system that independently predicted survival in patients with pancreatic adenocarcinoma...
  65. doi p16 Improves interobserver agreement in diagnosis of anal intraepithelial neoplasia
    Sarah M Bean
    Department of Pathology, Duke University Medical Center, Durham, NC, USA
    J Low Genit Tract Dis 13:145-53. 2009
    ....
  66. ncbi Antitumor efficacy of capecitabine and celecoxib in irradiated and lead-shielded, contralateral human BxPC-3 pancreatic cancer xenografts: clinical implications of abscopal effects
    Carmelo Blanquicett
    Division of Clinical Pharmacology, Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, Alabama 35294 3300, USA
    Clin Cancer Res 11:8773-81. 2005
    ..This chemoradiation regimen was chosen based on our molecular analysis of pancreatic adenocarcinoma...
  67. doi Histologic grading of invasive lobular carcinoma: does use of a 2-tiered nuclear grading system improve interobserver variability?
    Amy L Adams
    Department of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA
    Ann Diagn Pathol 13:223-5. 2009
    ..For ILC, where use of the NHG places substantial weight on nuclear pleomorphism, a 2-tiered nuclear grading system may reduce interobserver variability yet still provide useful prognostic information...
  68. ncbi Cytology and surgical pathology of the mediastinum
    Claudia Y Castro
    Immunohistochemistry Laboratory, Department of Pathology, University of Texas, Galveston, TX, USA
    Adv Exp Med Biol 563:42-54. 2005
  69. doi The Bethesda thyroid fine-needle aspiration classification system: year 1 at an academic institution
    Constantine G A Theoharis
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    Thyroid 19:1215-23. 2009
    ..The objective of this study was to report our experience in using this new reporting system to review the distribution of diagnosis categories and to evaluate the specificity of the system based on the cytologic-histologic correlation...
  70. ncbi Accuracy of reporting endocervical component adequacy--a continuous quality improvement project
    Janie Roberson
    Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama 35249 6823, USA
    Diagn Cytopathol 27:181-4. 2002
    ..Using reporting EC component adequacy as an example, we demonstrate that by treating clinical problems as quality control issues and applying basic quality improvement tools, a positive outcome can be effected...
  71. doi Using a higher cutoff for the percentage of HER2+ cells decreases interobserver variability in the interpretation of HER2 immunohistochemical analysis
    Omar Hameed
    Department of Pathology, University of Alabama School of Medicine, Birmingham, AL 35294 6823, USA
    Am J Clin Pathol 130:425-7. 2008
    ..001 for all comparisons). Using a 30% cutoff for the percentage of HER2+ cells by immunohistochemical analysis modestly decreased interobserver variability in the interpretation of HER2 immunohistochemical results...
  72. ncbi Atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion. A follow-up study of conventional and liquid-based preparations in a high-risk population
    Ana Paula Louro
    Department of Pathology, University of Alabama at Birmingham, 619 19 St S, KB 627, Birmingham, AL 35249 6823, USA
    Am J Clin Pathol 120:392-7. 2003
    ..Because of the high incidence of clinically significant lesions noted on subsequent follow-up, patients with an interpretation of ASC-H should be observed closely and referred for colposcopic examination regardless of their age...
  73. ncbi Use of mesothelin as a marker for mesothelial cells in cytologic specimens
    Cornelius Kachali
    Department of Pathology, University of Alabama, Birmingham, Alabama 35249 6823, USA
    Semin Diagn Pathol 23:20-4. 2006
    ..Therefore, mesothelin is not a sensitive or a specific marker for mesothelial cells in cytologic specimens when compared with calretinin...
  74. ncbi Atypical glandular cells--an update
    Joan F Cangiarella
    Department of Pathology, New York University Medical Center, New York, New York 10016, USA
    Diagn Cytopathol 29:271-9. 2003
    ..This article provides a comprehensive clinicopathologic review of the category of AGC...
  75. ncbi Expression of CEA, Tag-72, and Lewis-Y antigen in primary and metastatic lesions of ovarian carcinoma
    David C Chhieng
    Department of Pathology, University of Alabama, Birmingham 35249 6823, USA
    Hum Pathol 34:1016-21. 2003
    ..CEA (Col-1), due to its low expression and variation in phenotypic expression between primary and metastatic lesions, should be evaluated carefully in metastatic lesions before targeting the CEA antigen with CEA (Col-1)-like antibodies...
  76. ncbi Non-Hodgkin's lymphoma of the breast: a review of 18 primary and secondary cases
    Virginia E Duncan
    Department of Pathology, University of Alabama at Birmingham, 35249 7331, USA
    Ann Diagn Pathol 10:144-8. 2006
    ..Although rare, lymphoma should be considered in the differential diagnosis of a breast mass. Fine needle aspiration can facilitate appropriate triage of patients for further management...
  77. ncbi Increased expression of thymidylate synthetase (TS), ubiquitin specific protease 10 (USP10) and survivin is associated with poor survival in glioblastoma multiforme (GBM)
    Jessica M Grunda
    Departments of Pharmacology and Toxicology, Division of Clinical Pharmacology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA
    J Neurooncol 80:261-74. 2006
    ....
  78. ncbi Incidence and clinical significance of morphologically benign-appearing endometrial cells in patients age 40 years or older: the impact of the 2001 Bethesda System
    Sarah M Bean
    Department of Pathology, University of Alabama, Birmingham, Alabama 35249 6823, USA
    Cancer 108:39-44. 2006
    ..The objective of the current study was to determine whether there was any significant increase in the frequency with which this diagnosis was reported after the implementation of TBS 2001 and the clinical significance of this diagnosis...
  79. ncbi Women with atypical glandular cells: a long-term follow-up study in a high-risk population
    David C Chhieng
    Department of Pathology, University of Alabama at Birmingham, 35249 6823, USA
    Am J Clin Pathol 122:575-9. 2004
    ..Patients with AGCs are at risk of harboring clinically significant uterine lesions and should be followed up for a substantial period despite initial negative findings...
  80. doi Anal-rectal cytology: a review
    Sarah M Bean
    Department of Pathology, Division of Cytopathology, Duke University Medical Center, Durham, NC 27710, USA
    Diagn Cytopathol 38:538-46. 2010
    ..Patients with atypical squamous cells of undetermined significance (ASC-US) or worse should be referred for anoscopy...
  81. ncbi Endoscopic ultrasound-guided fine-needle aspiration in the diagnosis of foregut duplication cysts: the value of demonstrating detached ciliary tufts in cyst fluid
    Mohamad A Eloubeidi
    Division of Gastroenterology and Hepatology, Department of Medicine, University of Alabama Birmingham, Birmingham, Alabama 35294 0007, USA
    Cancer 102:253-8. 2004
    ..In this study, the authors describe the utility of demonstrating detached ciliary tufts (DCTs) in the diagnosis of foregut duplication cysts with EUS-FNA...
  82. ncbi Nuclear localization of KLF4 is associated with an aggressive phenotype in early-stage breast cancer
    Ashka Y Pandya
    Department of Cell Biology, University of Alabama at Birmingham, 35294, USA
    Clin Cancer Res 10:2709-19. 2004
    ..Although KLF4 expression is increased in most cases of breast cancer, it was unknown whether these cases represent a distinct subtype with a different clinical outcome...
  83. ncbi p53 and erbB-2 are not associated in matched cases of primary and metastatic ovarian carcinomas
    Cristina Rodriguez-Burford
    Department of Pathology, The University of Alabama at Birmingham, AL 35294, USA
    Dis Markers 19:11-7. 2003
    ..Thus, the nuclear accumulation of p53 and immunostaining of p185erbB-2 in the cytoplasm or on the cellular membranes are independent...
  84. ncbi Multiple late asymptomatic pancreatic metastases from renal cell carcinoma: diagnosis by endoscopic ultrasound-guided fine needle aspiration biopsy with immunocytochemical correlation
    Mohamad A Eloubeidi
    Department of Gastroenterology, The University of Alabama at Birmingham, 35294 0007, USA
    Dig Dis Sci 47:1839-42. 2002
    ..We conclude that EUS-FNA can provide tissue diagnosis from pancreatic masses, especially when other modalities have failed...
  85. ncbi Comparison of five antibodies as markers in the diagnosis of melanoma in cytologic preparations
    Matthew V Sheffield
    Department of Pathology, University of Alabama at Birmingham, 35249 6823, USA
    Am J Clin Pathol 118:930-6. 2002
    ..Mitf and Melan-A seem more specific than S-100 and tyrosinase. An antibody panel consisting of Mitf and Melan-A is superior to a panel of S-100 and HMB-45 in the diagnosis of melanoma in cytologic specimens...
  86. ncbi Assessment of biomarker expression in predicting pathologic response to neoadjuvant chemotherapy in patients with locally advanced breast cancer
    David C Chhieng
    Breast J 13:534-5. 2007