Research Topics
| Indrin J ChettySummaryAffiliation: University of Nebraska Medical Center Country: USA Publications
| Collaborators
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Detail Information
Publications
Report of the AAPM Task Group No. 105: Issues associated with clinical implementation of Monte Carlo-based photon and electron external beam treatment planningIndrin J Chetty
University of Michigan, Ann Arbor, Michigan 48109, USA
Med Phys 34:4818-53. 2007....- Dose reconstruction in deforming lung anatomy: dose grid size effects and clinical implicationsMihaela Rosu
Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan 48109 0010, USA
Med Phys 32:2487-95. 2005.... - The influence of beam model differences in the comparison of dose calculation algorithms for lung cancer treatment planningIndrin J Chetty
Department of Radiation Oncology, The University of Michigan, Ann Arbor, MI 48109 0010, USA
Phys Med Biol 50:801-15. 2005..This may ultimately hinder our ability to accurately correlate dose with clinical outcome... - Accounting for center-of-mass target motion using convolution methods in Monte Carlo-based dose calculations of the lungIndrin J Chetty
Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan 48109 0010, USA
Med Phys 31:925-32. 2004..This increase is not unexpected considering that the target spends relatively more time at inhale as the asymmetry decreases (note that the treatment plans were generated using the exhale CT scans)... - Experimental verification of a Monte Carlo-based MLC simulation model for IMRT dose calculationNeelam Tyagi
Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan 48109 0010, USA
Med Phys 34:651-63. 2007..Various sources of uncertainties in these comparisons are discussed... - Reporting and analyzing statistical uncertainties in Monte Carlo-based treatment planningIndrin J Chetty
Department of Radiation Oncology, The University of Michigan, Ann Arbor, MI 48109 0010, USA
Int J Radiat Oncol Biol Phys 65:1249-59. 2006..To investigate methods of reporting and analyzing statistical uncertainties in doses to targets and normal tissues in Monte Carlo (MC)-based treatment planning... - An anatomically realistic lung model for Monte Carlo-based dose calculationsLiang Liang
Department of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, Michigan 48109 2104, USA
Med Phys 34:1013-25. 2007..Future work with our model will involve patient motion, setup errors, and recommendations for the resolution of CT models... - Synchronized dynamic dose reconstructionDale W Litzenberg
University of Michigan, Ann Arbor Michigan 48109, USA
Med Phys 34:91-102. 2007..These reconstructed dose fractions can then be combined to produce high-quality determinations of the dose distribution actually received to date, from which individualized adaptive treatment strategies can be determined... - Monte Carlo-based lung cancer treatment planning incorporating PET-defined target volumesIndrin J Chetty
Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan 48109 0010, USA
J Appl Clin Med Phys 6:65-76. 2005..Further study with correlation to clinical outcome will be helpful in determining how to apply these various PET and CT volumes in treatment planning, to potentially improve local tumor control and reduce normal tissue toxicities... - Enhanced spectral discrimination through the exploitation of interface effects in photon dose dataPaule M Charland
Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan 48109, USA
Med Phys 31:264-76. 2004..Consequently, we suggest that as part of a beam-commissioning methodology, designated electronic disequilibrium test cases be implemented in unambiguously determining the correct energy spectrum to be used... - A fluence convolution method to account for respiratory motion in three-dimensional dose calculations of the liver: a Monte Carlo studyIndrin J Chetty
Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan 48109 0010, USA
Med Phys 30:1776-80. 2003.... - A proposed alternative to phase-space recycling using the adaptive kernel density estimator methodNeelam Tyagi
The University of Michigan Department of Nuclear Engineering and Radiological Sciences, Ann Arbor, Michigan 48109-2104, USA
Med Phys 33:553-60. 2006..AKDE calculated depth doses and profiles were within 2% and 2%/1 mm, respectively, of those computed using PS recycling... - Implementation of the DPM Monte Carlo code on a parallel architecture for treatment planning applicationsNeelam Tyagi
Department of Nuclear Engineering, The University of Michigan, Ann Arbor, Michigan 48109 2104, USA
Med Phys 31:2721-5. 2004..The phantom consists of layers of water, lung, bone, aluminum, and titanium. The agreement in the central axis depth dose curves and profiles at different depths shows that the serial and parallel codes are equivalent in accuracy... - A pilot study of [18F]fluorodeoxyglucose positron emission tomography scans during and after radiation-based therapy in patients with non small-cell lung cancerFeng Ming Spring Kong
Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
J Clin Oncol 25:3116-23. 2007..To study whether changes of [18F]fluorodeoxyglucose positron emission tomography (FDG-PET) during treatment correlate with post-treatment responses in tumor and normal lung in patients with non-small-cell lung cancer (NSCLC)... - Photon beam relative dose validation of the DPM Monte Carlo code in lung-equivalent mediaIndrin J Chetty
The University of Michigan, Department of Radiation Oncology, Ann Arbor, Michigan 48109 0010, USA
Med Phys 30:563-73. 2003..This work demonstrates that the DPM Monte Carlo code is capable of accurate photon beam dose calculations in situations where lateral electron disequilibrium effects are pronounced... - The impact of breathing motion versus heterogeneity effects in lung cancer treatment planningMihaela Rosu
Department of Radiation Oncology, The University of Michigan, Ann Arbor Michigan 48109 0010, USA
Med Phys 34:1462-73. 2007..AP/PA versus 3D-CRT. Given a properly designed ITV, tissue heterogeneity effects are likely to have a larger clinical significance on tumor and normal lung treatment evaluation metrics than four-dimensional respiratory-induced changes... 
Dosimetric consequences of intrafraction prostate motionHaisen S Li
Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE, USA
Int J Radiat Oncol Biol Phys 71:801-12. 2008..To analyze characteristics of intrafraction prostate motion, monitored using the Calypso system, and investigate dosimetric consequences of the motion for different clinical target volume (CTV) to planning target volume (PTV) margins...- Experimental verification and clinical implementation of a commercial Monte Carlo electron beam dose calculation algorithmMargarida Fragoso
University of Nebraska Medical Center, Omaha, Nebraska 68198 7521, USA
Med Phys 35:1028-38. 2008..3 cm. Timing values ranged from 2 min to 24.5 h, depending on the field size, beam energy, number, and thickness of computed tomography slices used to define the patient's anatomy for the overall uncertainty values mentioned above... - How extensive of a 4D dataset is needed to estimate cumulative dose distribution plan evaluation metrics in conformal lung therapy?Mihaela Rosu
The University of Michigan, Department of Radiation Oncology, Ann Arbor Michigan 48109 0010, USA
Med Phys 34:233-45. 2007.... - Benchmarking of the dose planning method (DPM) Monte Carlo code using electron beams from a racetrack microtronIndrin J Chetty
The University of Michigan, Department of Radiation Oncology, Ann Arbor 48109 0010, USA
Med Phys 29:1035-41. 2002..The accuracy of the DPM code illustrated in this work suggests that DPM may be used as a valuable tool for electron beam dose calculations... - A Monte Carlo based phase space model for quality assurance of intensity modulated radiotherapy incorporating leaf specific characteristicsRandi F Aaronson
Department of Radiation Oncology, University of California, Los Angeles, California 90095 6951, USA
Med Phys 29:2952-8. 2002..53 criteria for all benchmark fields used. Film dosimetry was used to evaluate the model for IMRT sequences and plans, and the ability of the model to account for leaf sequencing effects is also demonstrated... - Experimental validation of the DPM Monte Carlo code using minimally scattered electron beams in heterogeneous mediaIndrin J Chetty
Department of Radiation Oncology, The University of Michigan, Ann Arbor 48109 0010, USA
Phys Med Biol 47:1837-51. 2002.... 
Quantifying the interplay effect in prostate IMRT delivery using a convolution-based methodHaisen S Li
Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, Nebraska 68198 7521, USA
Med Phys 35:1703-10. 2008..3%, in single fraction plans. For entire treatment courses delivered in either a hypofractionated (five fractions) or conventional (> 30 fractions) regimen, the discrepancy in total dose due to interplay effect was negligible...- Dosimetric comparison of extended dose range film with ionization measurements in water and lung equivalent heterogeneous media exposed to megavoltage photonsPaule M Charland
Department of Radiation Oncology, The University of Michigan, Ann Arbor, Michigan 48109 0010, USA
J Appl Clin Med Phys 4:25-39. 2003..From this investigation EDR film appears to be a useful medium for relative dosimetry in higher dose ranges in both water and lung equivalent material for moderate field sizes and depths... - Investigation of Kodak extended dose range (EDR) film for megavoltage photon beam dosimetryIndrin J Chetty
Department of Radiation Oncology, The University of Michigan, Ann Arbor 48109 0010, USA
Phys Med Biol 47:3629-41. 2002..The results of this study indicate that Kodak EDR film may be a useful tool for relative dosimetry at higher dose ranges...