R W Chesney

Summary

Affiliation: University of Tennessee
Country: USA

Publications

  1. ncbi request reprint Gating of taurine transport: role of the fourth segment of the taurine transporter
    Xiaobin Han
    Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA
    Adv Exp Med Biol 526:149-57. 2003
  2. ncbi request reprint Children as clinical research subjects
    Russell W Chesney
    Department of Pediatrics, University of Tennessee Health Science Center, Le Bonheur Children s Medical Center, St Jude Children s Research Hospital, 50 North Dunlap Street, Memphis, TN 38103, USA
    J Pediatr 146:579-80. 2005
  3. doi request reprint Rickets in lion cubs at the London Zoo in 1889: some new insights
    Russell W Chesney
    University of Tennessee Health Science Center, Department of Pediatrics, Children s Foundation Research Center, Le Bonheur Children s Medical Center, Memphis, TN 38103, USA
    Pediatrics 123:e948-50. 2009
  4. ncbi request reprint Rickets: an old form for a new century
    Russell W Chesney
    Department of Pediatrics, The University of Tennessee Health Science Center, Le Bonheur Children s Medical Center, Memphis, Tennessee 38103 4909, USA
    Pediatr Int 45:509-11. 2003
  5. ncbi request reprint The future of pediatric nephrology
    Russell W Chesney
    Department of Pediatrics, University of Tennessee Health Science Center, 50 N Dunlap, Room 306, Memphis, TN 38103, USA
    Pediatr Nephrol 20:867-71. 2005
  6. ncbi request reprint American Pediatric Society Presidential Address 2003: the failure of Ockham's razor in 21st century pediatrics
    Russell W Chesney
    University of Tennessee Health Science Center, Department of Pediatrics, Le Bonheur Children s Medical Center, 50 N Dunlap, Room 306 307, Memphis, TN 38103, USA
    Pediatr Res 55:903-7. 2004
  7. ncbi request reprint Changing requirements for evaluation of pharmacologic agents
    Russell W Chesney
    Department of Pediatrics, Center for Pediatric Pharmacokinetics and Therapeutics, University of Tennessee, Memphis, USA
    Pediatrics 113:1128-32. 2004
  8. ncbi request reprint The changing face of childhood nephrotic syndrome
    Russell Chesney
    Department of Pediatrics, LeBonheur Children s Medical Center, and the University of Tennessee College of Medicine, Memphis, Tennessee 38103, USA
    Kidney Int 66:1294-302. 2004
  9. ncbi request reprint Report of an NIH task force on research priorities in chronic kidney disease in children
    Russell W Chesney
    Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, 38103 4909, USA
    Pediatr Nephrol 21:14-25. 2006
  10. ncbi request reprint The pleasure of lifelong learning
    Russell W Chesney
    Department of Pediatrics, University of Tennessee, Health Science Center, College of Medicine, Memphis 38103, USA
    Pharos Alpha Omega Alpha Honor Med Soc 67:32. 2004

Detail Information

Publications41

  1. ncbi request reprint Gating of taurine transport: role of the fourth segment of the taurine transporter
    Xiaobin Han
    Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA
    Adv Exp Med Biol 526:149-57. 2003
  2. ncbi request reprint Children as clinical research subjects
    Russell W Chesney
    Department of Pediatrics, University of Tennessee Health Science Center, Le Bonheur Children s Medical Center, St Jude Children s Research Hospital, 50 North Dunlap Street, Memphis, TN 38103, USA
    J Pediatr 146:579-80. 2005
  3. doi request reprint Rickets in lion cubs at the London Zoo in 1889: some new insights
    Russell W Chesney
    University of Tennessee Health Science Center, Department of Pediatrics, Children s Foundation Research Center, Le Bonheur Children s Medical Center, Memphis, TN 38103, USA
    Pediatrics 123:e948-50. 2009
    ..However, gum health and the presence of taurine-conjugated bile salts undoubtedly permitted absorption of vitamin A and D, the latter promoting the cure of rickets...
  4. ncbi request reprint Rickets: an old form for a new century
    Russell W Chesney
    Department of Pediatrics, The University of Tennessee Health Science Center, Le Bonheur Children s Medical Center, Memphis, Tennessee 38103 4909, USA
    Pediatr Int 45:509-11. 2003
  5. ncbi request reprint The future of pediatric nephrology
    Russell W Chesney
    Department of Pediatrics, University of Tennessee Health Science Center, 50 N Dunlap, Room 306, Memphis, TN 38103, USA
    Pediatr Nephrol 20:867-71. 2005
    ..The International Pediatric Nephrology Association (IPNA), its journal, and pediatric advocates will need to use their energies to take on these challenges...
  6. ncbi request reprint American Pediatric Society Presidential Address 2003: the failure of Ockham's razor in 21st century pediatrics
    Russell W Chesney
    University of Tennessee Health Science Center, Department of Pediatrics, Le Bonheur Children s Medical Center, 50 N Dunlap, Room 306 307, Memphis, TN 38103, USA
    Pediatr Res 55:903-7. 2004
  7. ncbi request reprint Changing requirements for evaluation of pharmacologic agents
    Russell W Chesney
    Department of Pediatrics, Center for Pediatric Pharmacokinetics and Therapeutics, University of Tennessee, Memphis, USA
    Pediatrics 113:1128-32. 2004
    ..This article reviews new laws that govern drug testing in children and the use of children in therapeutic research...
  8. ncbi request reprint The changing face of childhood nephrotic syndrome
    Russell Chesney
    Department of Pediatrics, LeBonheur Children s Medical Center, and the University of Tennessee College of Medicine, Memphis, Tennessee 38103, USA
    Kidney Int 66:1294-302. 2004
  9. ncbi request reprint Report of an NIH task force on research priorities in chronic kidney disease in children
    Russell W Chesney
    Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, 38103 4909, USA
    Pediatr Nephrol 21:14-25. 2006
  10. ncbi request reprint The pleasure of lifelong learning
    Russell W Chesney
    Department of Pediatrics, University of Tennessee, Health Science Center, College of Medicine, Memphis 38103, USA
    Pharos Alpha Omega Alpha Honor Med Soc 67:32. 2004
  11. ncbi request reprint Primary hyperparathyroidism in pediatric patients: clear-cut differences from adult patients
    Russell W Chesney
    Department of Pediatrics, University of Tennessee Health Science Center, 50 N Dunlop, Memphis, TN 38103, USA
    Pediatrics 115:1073. 2005
  12. ncbi request reprint Racial disparities in renal transplantation in children
    Russell W Chesney
    Department of Pediatrics, University of Tennessee Health Science Center, LeBonheur Children s Medical Center, Memphis, TN 38103, USA
    Pediatrics 112:409-11. 2003
  13. doi request reprint Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR): background commentary of RIVUR investigators
    Russell W Chesney
    University of Tennessee Health Science Center, Department of Pediatrics, Memphis, TN 38103, USA
    Pediatrics 122:S233-9. 2008
    ..Such recommendations should be evidence-based...
  14. doi request reprint Does taurine deficiency cause metabolic bone disease and rickets in polar bear cubs raised in captivity?
    Russell W Chesney
    The University of Tennessee Health Science Center, USA
    Adv Exp Med Biol 643:325-31. 2009
    ..Higher dietary intake of TAU by free-ranging cubs may influence bile acid conjugation and improve vitamin D absorption...
  15. ncbi request reprint Who was John Howland and why was an award named after him 50 years ago?
    Russell W Chesney
    Department of Pediatrics, University of Tennessee Health Science Center, LeBonheur Children s Medical Center, Memphis, Tennessee 38103, USA
    Pediatr Res 53:523-5. 2003
  16. ncbi request reprint The development of pediatric nephrology
    Russell W Chesney
    Department of Pediatrics, University of Tennessee College of Medicine, LeBonheur Children s Medical Center, Memphis, Tennessee 38103, USA
    Pediatr Res 52:770-8. 2002
    ..The scientific basis of pediatric nephrology, ongoing patient care needs, and its technical aspects - renal biopsy, dialysis and transplantation - assure its continuing future as a major pediatric discipline on all continents...
  17. ncbi request reprint Bone mineral density in chronic renal insufficiency and end-stage renal disease: how to interpret the scans
    Russell W Chesney
    Department of Pediatrics University of Tennessee Health Science Center Memphis, TN 38103, USA
    J Pediatr Endocrinol Metab 17:1327-32. 2004
    ..The strengths and limitations of these imaging techniques are discussed extensively...
  18. ncbi request reprint Transcriptional repression of taurine transporter gene (TauT) by p53 in renal cells
    Xiaobin Han
    Department of Pediatrics, University of Tennessee Health Science Center and the Children s Foundation Research Center at Le Bonheur Children s Medical Center, Memphis, Tennessee 38103, USA
    J Biol Chem 277:39266-73. 2002
    ..Mutation of this p53 consensus sequence abolished binding of p53. These results demonstrate that TauT may represent a downstream target gene of p53 that could link the roles of p53 in renal development and apoptosis...
  19. pmc Rationale and design issues of the Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR) study
    Ron Keren
    Department of Pediatrics, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Pediatrics 122:S240-50. 2008
    ....
  20. ncbi request reprint The taurine transporter: mechanisms of regulation
    X Han
    Department of Pediatrics, The University of Tennessee Health Science Center, Memphis, TN 38103, USA
    Acta Physiol (Oxf) 187:61-73. 2006
    ....
  21. ncbi request reprint Regulation of TauT by cisplatin in LLC-PK1 renal cells
    X Han
    Department of Pediatrics, University of Tennessee, Memphis, 38103, USA
    Pediatr Nephrol 20:1067-72. 2005
    ..The mechanism by which TauT serves as an anti-apoptotic gene in cisplatin-induced renal injury remains to be determined, but could relate to taurine-dependent cell volume regulation...
  22. ncbi request reprint Regulation of taurine transporter gene (TauT) by WT1
    Xiaobin Han
    Department of Pediatrics, University of Tennessee Health Science Center, and the Children s Foundation Research Center at Le Bonheur Children s Medical Center, 50 North Dunlap, Memphis, TN 38103 4909, USA
    FEBS Lett 540:71-6. 2003
    ..Mutation of this WT1 consensus sequence abolished binding of WT1. These results demonstrate that TauT may represent a downstream target gene of WT1 during renal development...
  23. doi request reprint Mechanism of TauT in protecting against cisplatin-induced kidney injury (AKI)
    Xiaobin Han
    Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA
    Adv Exp Med Biol 643:105-12. 2009
    ....
  24. ncbi request reprint Is TauT an anti-apoptotic gene?
    Xiaobin Han
    Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA
    Adv Exp Med Biol 583:59-67. 2006
  25. doi request reprint TauT protects against cisplatin-induced acute kidney injury (AKI) established in a TauT transgenic mice model
    Xiaobin Han
    Department of Pediatrics, University of Tennessee Health Science Center and the Children s Memphis, TN, USA
    Adv Exp Med Biol 643:113-22. 2009
    ..06 mg/dl). However, over-expression of hTauT effectively prevented the progression of cisplatin-induced AKI in hTauT transgenic mice, as measured by the levels of BUN and serum creatininelevels (23 +/- 3.5 mg/dl and 0.6 +/- 0.05 mg/dl)...
  26. ncbi request reprint Mechanisms of regulation of taurine transporter activity: a complex interplay of regulatory systems
    Xiaobin Han
    Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA
    Adv Exp Med Biol 583:79-90. 2006
  27. ncbi request reprint Increased parathyroid hormone and decreased calcitriol during neonatal extracorporeal membrane oxygenation
    Emily B Hak
    Department of Pharmacy, University of Tennessee Health Science Center, 26 South Dunlap, Memphis, Tenn 38163, USA
    Intensive Care Med 31:264-70. 2005
    ..We studied the pathogenesis of hypercalcemia and hypomagnesemia by evaluating calcitriol, intact parathyroid hormone, and calcitonin status during extracorporeal membrane oxygenation...
  28. pmc Functional TauT protects against acute kidney injury
    Xiaobin Han
    Department of Pediatrics, University of Tennessee Health Science Center, 50 North Dunlap, Room 301 WPT, Memphis, TN 38103, USA
    J Am Soc Nephrol 20:1323-32. 2009
    ..These data suggest that functional TauT plays a critical role in protecting against cisplatin-induced nephrotoxicity, possibly by attenuating a p53-dependent pathway...
  29. ncbi request reprint Rickets secondary to phosphate depletion. A sequela of antacid use in infancy
    E K Pivnick
    Department of Pediatrics, University of Tennessee, Memphis 38105, USA
    Clin Pediatr (Phila) 34:73-8. 1995
    ..Therefore, antacid therapy should be used in low doses and very cautiously, with routine monitoring of serum calcium and phosphorus in children taking medications which reduce gastrointestinal phosphate absorption...
  30. ncbi request reprint Transactivation of TauT by p53 in MCF-7 cells: the role of estrogen receptors
    Xiaobin Han
    Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, USA
    Adv Exp Med Biol 526:139-47. 2003
  31. ncbi request reprint Ser-322 is a critical site for PKC regulation of the MDCK cell taurine transporter (pNCT)
    X Han
    Department of Pediatrics, University of Tennessee, and the Crippled Children s Foundation Research Center at Le Bonheur Children s Medical Center, Memphis 38103, USA
    J Am Soc Nephrol 10:1874-9. 1999
    ..The steady-state taurine transporter activity is tightly controlled by endogenous PKC phosphorylation of Ser-322, which is located in the fourth intracellular segment of the taurine transporter...
  32. ncbi request reprint Rickets: the third wave
    Russell W Chesney
    The University of Tennessee Health Sciences Center, Memphis 38103, USA
    Clin Pediatr (Phila) 41:137-9. 2002
  33. ncbi request reprint Pamidronate in a girl with chronic renal insufficiency dependent on parenteral nutrition
    Janet L Duke
    Department of Pharmacy, The Center for Pediatric Pharmacokinetics and Therapeutics, Pediatric Pharmacology Research Unit, University of Tennessee Health Science Center, Tennessee, USA
    Pediatr Nephrol 18:714-7. 2003
    ..We conclude that relatively large doses of pamidronate may be required in certain cases of refractory hypercalcemia and are well tolerated in children...
  34. ncbi request reprint Women pediatricians: can facts shed light on prejudices and myths?
    Russell W Chesney
    Department of Pediatrics, University of Tennessee Health Science Center, LeBonheur Children s Medical Center, Memphis, Tennessee, USA
    J Pediatr 144:413-4. 2004
  35. ncbi request reprint Why physicians are certified by boards
    Russell W Chesney
    Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    J Pediatr 141:299. 2002
  36. doi request reprint Linking process to outcome: are we training pediatricians to meet evolving health care needs?
    M Douglas Jones
    Department of Pediatrics, University of Colorado Denver, School of Medicine, Aurora, CO 80045, USA
    Pediatrics 123:S1-7. 2009
    ....
  37. ncbi request reprint Why is the oncogene WT1 in the developing kidney and what is it doing there?
    Russell W Chesney
    Pediatr Nephrol 17:990-2. 2002
  38. ncbi request reprint Pediatric practice and education in the genomic/postgenomic era
    Russell W Chesney
    J Pediatr 141:453-8. 2002
  39. ncbi request reprint The role of the kidney in protecting the brain against cerebral edema and neuronal cell swelling
    Russell W Chesney
    J Pediatr 152:4-6. 2008
  40. ncbi request reprint The changing face of pediatrics: where is our discipline headed?
    Russell W Chesney
    J Pediatr 147:415-6. 2005
  41. ncbi request reprint How many pediatricians? Pitfalls in analysis and possible approaches
    Russell W Chesney
    J Pediatr 143:550-2. 2003