G M Chertow

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Race/ethnicity and disease severity in IgA nephropathy
    Yoshio N Hall
    Division of Nephrology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    BMC Nephrol 5:10. 2004
  2. ncbi Lessons for Medicare Part D in the hemodialysis community
    Anisa I Nayeem
    Division of Nephrology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    BMC Nephrol 7:11. 2006
  3. ncbi Survival after acute myocardial infarction in patients with end-stage renal disease: results from the cooperative cardiovascular project
    G M Chertow
    Division of Nephrology, Moffitt Long Hospitals and UCSF Mount Zion Medical Center, Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Am J Kidney Dis 35:1044-51. 2000
  4. ncbi Ochrobactrum anthropi bacteremia in a patient on hemodialysis
    G M Chertow
    Divisions of Nephrology, Moffitt Long Hospitals and UCSF Mount Zion Medical Center, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
    Am J Kidney Dis 35:E30. 2000
  5. ncbi Update on adverse drug events associated with parenteral iron
    Glenn M Chertow
    Department of Medicine, University of California San Francisco, UCSF Laurel Heights Suite 430, 3333 California Street, San Francisco, CA 94118 1211, USA
    Nephrol Dial Transplant 21:378-82. 2006
  6. ncbi Prealbumin is as important as albumin in the nutritional assessment of hemodialysis patients
    G M Chertow
    Divisions of Nephrology, Moffitt Long Hospitals and UCSF Mt Zion Medical Center, and Departments of Medicine and Nutrition, University of California, San Francisco, California 94143 0532, USA
    Kidney Int 58:2512-7. 2000
  7. ncbi Studying the prevention of acute kidney injury: lessons from an 18th-century mathematician
    Glenn M Chertow
    Division of Nephrology, Department of Medicine, University of California San Francisco, San Francisco, California, USA
    Clin J Am Soc Nephrol 1:1124-7. 2006
  8. ncbi The tortoise and hare on hemodialysis: does slow and steady win the race?
    G M Chertow
    Department of Medicine, University of California, San Francisco, California 94118, USA
    Kidney Int 70:24-5. 2006
  9. ncbi Timing of initiation of dialysis in critically ill patients with acute kidney injury
    Kathleen D Liu
    Division of Nephrology, Department of Medicine, University of California San Francisco, USA
    Clin J Am Soc Nephrol 1:915-9. 2006
  10. ncbi With bioimpedance spectroscopy, the errors get fat when the patients get slim
    Glenn M Chertow
    JPEN J Parenter Enteral Nutr 26:128-9. 2002

Research Grants

  1. Hospital and Community Acquired Acute Renal Failure
    Glenn Chertow; Fiscal Year: 2006
  2. FREEDOM - Frequent Dialysis Outcomes & Markers Study
    Glenn Chertow; Fiscal Year: 2006

Collaborators

Detail Information

Publications118 found, 100 shown here

  1. ncbi Race/ethnicity and disease severity in IgA nephropathy
    Yoshio N Hall
    Division of Nephrology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    BMC Nephrol 5:10. 2004
    ..Clinical reports suggest that Asian/Pacific Islanders are more likely to be affected by IgA nephropathy (IgAN), and that the severity of disease is increased in these populations...
  2. ncbi Lessons for Medicare Part D in the hemodialysis community
    Anisa I Nayeem
    Division of Nephrology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    BMC Nephrol 7:11. 2006
    ....
  3. ncbi Survival after acute myocardial infarction in patients with end-stage renal disease: results from the cooperative cardiovascular project
    G M Chertow
    Division of Nephrology, Moffitt Long Hospitals and UCSF Mount Zion Medical Center, Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Am J Kidney Dis 35:1044-51. 2000
    ..In light of the exceptionally poor outcomes observed for patients treated with medical therapy alone, it may be premature to dismiss PTCA as a therapeutic option in this population...
  4. ncbi Ochrobactrum anthropi bacteremia in a patient on hemodialysis
    G M Chertow
    Divisions of Nephrology, Moffitt Long Hospitals and UCSF Mount Zion Medical Center, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
    Am J Kidney Dis 35:E30. 2000
    ....
  5. ncbi Update on adverse drug events associated with parenteral iron
    Glenn M Chertow
    Department of Medicine, University of California San Francisco, UCSF Laurel Heights Suite 430, 3333 California Street, San Francisco, CA 94118 1211, USA
    Nephrol Dial Transplant 21:378-82. 2006
    ..Since that time, iron sucrose has become widely available and clinicians have gained additional experience with sodium ferric gluconate complex...
  6. ncbi Prealbumin is as important as albumin in the nutritional assessment of hemodialysis patients
    G M Chertow
    Divisions of Nephrology, Moffitt Long Hospitals and UCSF Mt Zion Medical Center, and Departments of Medicine and Nutrition, University of California, San Francisco, California 94143 0532, USA
    Kidney Int 58:2512-7. 2000
    ..In this study, we aimed to determine the independent association of serum prealbumin with survival in hemodialysis patients, after adjusting for serum albumin and other indicators of protein energy nutritional status...
  7. ncbi Studying the prevention of acute kidney injury: lessons from an 18th-century mathematician
    Glenn M Chertow
    Division of Nephrology, Department of Medicine, University of California San Francisco, San Francisco, California, USA
    Clin J Am Soc Nephrol 1:1124-7. 2006
  8. ncbi The tortoise and hare on hemodialysis: does slow and steady win the race?
    G M Chertow
    Department of Medicine, University of California, San Francisco, California 94118, USA
    Kidney Int 70:24-5. 2006
    ..In this report, we review two recently published observational studies examining the association between hemodialysis session length and survival. Prospective clinical trials will be required to resolve the debate...
  9. ncbi Timing of initiation of dialysis in critically ill patients with acute kidney injury
    Kathleen D Liu
    Division of Nephrology, Department of Medicine, University of California San Francisco, USA
    Clin J Am Soc Nephrol 1:915-9. 2006
    ..Although the results could reflect residual confounding by severity of illness, they provide a rationale for prospective testing of alternative dialysis initiation strategies in critically ill patients with severe AKI...
  10. ncbi With bioimpedance spectroscopy, the errors get fat when the patients get slim
    Glenn M Chertow
    JPEN J Parenter Enteral Nutr 26:128-9. 2002
  11. ncbi Cinacalcet hydrochloride (Sensipar) in hemodialysis patients on active vitamin D derivatives with controlled PTH and elevated calcium x phosphate
    Glenn M Chertow
    Department of Medicine, University of California, San Francisco, School of Medicine, San Francisco, California, USA
    Clin J Am Soc Nephrol 1:305-12. 2006
    ..The long-term effects of this treatment regimen on clinical outcomes should be tested prospectively...
  12. ncbi Mortality after acute renal failure: models for prognostic stratification and risk adjustment
    G M Chertow
    Department of Medicine Research, Division of Nephrology, University of California San Francisco, San Francisco, California, USA
    Kidney Int 70:1120-6. 2006
    ..By incorporating exposures over time, the discriminatory power of predictive models in ARF can be significantly improved...
  13. ncbi Acute kidney injury, mortality, length of stay, and costs in hospitalized patients
    Glenn M Chertow
    Division of Nephrology, Department of Medicine, University of California San Francisco, 94118 1211, USA
    J Am Soc Nephrol 16:3365-70. 2005
    ..Moreover, outcomes are related directly to the severity of acute kidney injury, whether characterized by nominal or percentage changes in serum creatinine...
  14. ncbi Guided medication dosing for inpatients with renal insufficiency
    G M Chertow
    Department of Medicine Research, UCSF Laurel Heights, 3333 California St, Suite 430, San Francisco, CA 94118, USA
    JAMA 286:2839-44. 2001
    ..Usual drug-prescribing practices may not consider the effects of renal insufficiency on the disposition of certain drugs. Decision aids may help optimize prescribing behavior and reduce medical error...
  15. ncbi The effects of sevelamer and calcium acetate on proxies of atherosclerotic and arteriosclerotic vascular disease in hemodialysis patients
    Glenn M Chertow
    Division of Nephrology, Moffitt Long Hospitals and UCSF Mt Zion Medical Center, Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Am J Nephrol 23:307-14. 2003
    ..Whether the specific calcium preparation (acetate vs. carbonate) might influence the likelihood of progressive calcification was debated...
  16. ncbi "Renalism": inappropriately low rates of coronary angiography in elderly individuals with renal insufficiency
    Glenn M Chertow
    Department of Medicine Research, University of California San Francisco, UCSF Laurel Heights Suite 430, 3333 California Street, San Francisco, CA 94118 1211, USA
    J Am Soc Nephrol 15:2462-8. 2004
    ....
  17. ncbi On the relative safety of parenteral iron formulations
    Glenn M Chertow
    Division of Nephrology, Department of Medicine, University of California San Francisco, 94118 1211, USA
    Nephrol Dial Transplant 19:1571-5. 2004
    ..Randomized clinical trials may have insufficient power to detect differences in the safety profiles of specific formulations...
  18. ncbi Determinants of progressive vascular calcification in haemodialysis patients
    Glenn M Chertow
    Division of Nephrology, Moffitt Long Hospitals and UCSF Mt Zion Medical Center, Department of Medicine, University of California San Francisco, 94118 1211, USA
    Nephrol Dial Transplant 19:1489-96. 2004
    ..Aside from the provision of calcium, we hypothesized that other factors might be related to the likelihood of progressive calcification in both or either treatment groups...
  19. ncbi Prealbumin, mortality, and cause-specific hospitalization in hemodialysis patients
    Glenn M Chertow
    Division of Nephrology, Departments of Medicine, Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA 94118 1211, USA
    Kidney Int 68:2794-800. 2005
    ..Prior studies have suggested that the serum prealbumin concentration is independently associated with mortality in hemodialysis patients, even with adjustment for serum albumin and other nutritional parameters...
  20. ncbi A 43-year-old woman with chronic renal insufficiency
    Glenn M Chertow
    Division of Nephrology, Moffitt-Long Hospitals and UCSF-Mt Zion Medical Center, Department of Medicine, University of California, San Francisco 94118-1211, USA
    JAMA 291:1252-9. 2004
  21. ncbi Reasons for non-enrollment in a cohort study of ARF: the Program to Improve Care in Acute Renal Disease (PICARD) experience and implications for a clinical trials network
    Glenn M Chertow
    Department of Medicine Research, University of California San Francisco, San Francisco, CA 94118 1211, USA
    Am J Kidney Dis 42:507-12. 2003
    ..Previous clinical trials of ARF have been hampered by the heterogeneous population affected, difficulty defining ARF, delays in identification of ARF, and significant comorbid conditions, among other factors...
  22. ncbi Slowing the progression of vascular calcification in hemodialysis
    Glenn M Chertow
    Department of Medicine, University of California San Francisco, San Francisco, California 94118 1211, USA
    J Am Soc Nephrol 14:S310-4. 2003
    ..Strategies that use oral calcium and vitamin D in patients with ESRD should be reexamined, and the potential advantages of sevelamer should be considered when selecting a primary agent to reduce serum phosphorus in hemodialysis patients...
  23. ncbi Modality-specific nutrition support in ESRD: weighing the evidence
    G M Chertow
    Department of Medicine, Metabolic Support Service, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Am J Kidney Dis 33:193-7. 1999
    ..Prospective clinical trials investigating the effects of nutrition support on survival, hospitalization rates, health-related quality of life, and functional status, are urgently needed...
  24. ncbi Exploring the reverse J-shaped curve between urea reduction ratio and mortality
    G M Chertow
    Division of Nephrology, University of California, San Francisco, 94143, USA
    Kidney Int 56:1872-8. 1999
    ....
  25. ncbi Vintage, nutritional status, and survival in hemodialysis patients
    G M Chertow
    Division of Nephrology, Moffitt Long Hospitals, San Francisco, California, USA
    Kidney Int 57:1176-81. 2000
    ..End-stage renal disease (ESRD) is thought to be a wasting illness, but there are no published reports describing the associations between vintage and body composition in hemodialysis patients...
  26. ncbi Physical activity levels in patients on hemodialysis and healthy sedentary controls
    K L Johansen
    Divisions of Nephrology, San Francisco VA Medical Center, San Francisco, California 94121, USA
    Kidney Int 57:2564-70. 2000
    ..The purpose of the current study was to determine whether patients on hemodialysis are less active than healthy sedentary controls and to explore clinical correlates of physical activity level in a group of hemodialysis patients...
  27. ncbi Mortality and costs of acute renal failure associated with amphotericin B therapy
    D W Bates
    Division of General Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Clin Infect Dis 32:686-93. 2001
    ..Although residual confounding exists despite adjustment, the increases in resource utilization that we found are large and the associated mortality is high when acute renal failure occurs following amphotericin B therapy...
  28. ncbi Beta 2-microglobulin modified with advanced glycation end products modulates collagen synthesis by human fibroblasts
    W F Owen
    Department of Medicine, Brigham and Women s Hospital Harvard Medical School, Boston, Massachusetts, USA
    Kidney Int 53:1365-73. 1998
    ..These findings support the hypothesis that beta 2m-AGE actively participates in connective tissue and bone remodeling via a pathway involving fibroblast RAGE, and at least one interposed mediator, the growth factor EGF...
  29. ncbi The influence of patient- and facility-specific factors on nutritional status and survival in hemodialysis
    George A Kaysen
    Division of Nephrology, Department of Medicine, University of California Davis, Davis, CA 94118-1211, USA
    J Ren Nutr 14:72-81. 2004
    ..The associations of nutritional parameters with mortality and hospitalization vary by age, sex, and vintage but not by facility-specific factors, including those associated with the nutritional parameters themselves...
  30. ncbi Dose of hemodialysis and survival: differences by race and sex
    W F Owen
    Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    JAMA 280:1764-8. 1998
    ..Previous studies of the relationship between the dose of dialysis and patient survival have not controlled for differences in patient characteristics...
  31. ncbi PTH and the risks for hip, vertebral, and pelvic fractures among patients on dialysis
    Mark D Danese
    Outcomes Insights, Newbury Park, CA, USA
    Am J Kidney Dis 47:149-56. 2006
    ....
  32. ncbi The risk of acute renal failure in patients with chronic kidney disease
    C Y Hsu
    Department of Medicine, University of California, San Francisco, California 94143 0532, USA
    Kidney Int 74:101-7. 2008
    ..Several common risk factors for chronic kidney disease also increase the peril of nosocomial acute kidney failure...
  33. ncbi Preoperative renal risk stratification
    G M Chertow
    Renal Section, Brockton West Roxbury Department of Veteran Affairs Medical Center, Boston, Mass, USA
    Circulation 95:878-84. 1997
    ..Prior studies have attempted to identify predictors of ARF but have had insufficient power to perform multivariable analyses or to develop risk stratification algorithms...
  34. ncbi Dialysis-requiring acute renal failure increases the risk of progressive chronic kidney disease
    Lowell J Lo
    Department of Medicine, University of California, San Francisco, 94143 0532, USA
    Kidney Int 76:893-9. 2009
    ....
  35. ncbi Differential mortality and transplantation rates among Asians and Pacific Islanders with ESRD
    Yoshio N Hall
    Departments of Medicine, University of California San Francisco, San Francisco, CA 94118-1211, USA
    J Am Soc Nephrol 16:3711-20. 2005
    ..Strategies that are aimed at improving access to transplantation in Asian and Pacific Islander communities may further enhance survival among Asians and Pacific Islanders with ESRD...
  36. ncbi Refining predictive models in critically ill patients with acute renal failure
    Ravindra L Mehta
    Division of Nephrology, University of California, San Diego Medical Center, San Diego, California 92103, USA
    J Am Soc Nephrol 13:1350-7. 2002
    ..Cross-validation of the model and additional bedside experience will be needed before it can be effectively applied across centers, particularly in the context of clinical trials...
  37. ncbi Inflammatory markers are unrelated to physical activity, performance, and functioning in hemodialysis
    Adriana M Hung
    San Francisco VA Medical Center, Division of Nephrology, San Francisco, CA 94121, USA
    J Ren Nutr 12:170-6. 2002
    ..More research is required to understand the role of cytokines in protein energy malnutrition and the mechanisms of wasting and functional decline in the dialysis population...
  38. ncbi Antigen-independent determinants of cadaveric kidney transplant failure
    G M Chertow
    Renal Division, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    JAMA 276:1732-6. 1996
    ..To determine the association of various antigen-independent factors with long-term cadaveric kidney transplant failure...
  39. ncbi Development of a population-specific regression equation to estimate total body water in hemodialysis patients
    G M Chertow
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Kidney Int 51:1578-82. 1997
    ..The use of formulae developed and validated in non-uremic populations may result in underestimates of TBW in patients with ESRD, and potentially, overestimates of dialysis dose approximated by the clearance-time to TBW ratio (Kt/V)...
  40. ncbi Cognitive impairment in chronic kidney disease
    Manjula Kurella
    Divison of Nephrology, University of California at San Francisco, San Francisco, CA 94143, USA
    J Am Geriatr Soc 52:1863-9. 2004
    ..CONCLUSION: Cognitive impairment is associated with the severity of kidney disease. Further studies are needed to determine the reasons for cognitive impairment in subjects with CKD and ESRD...
  41. ncbi Challenging the validity of the EPO index
    George A Kaysen
    Division of Nephrology, Department of Medicine, University of California Davis, Department of Veterans Affairs, Medical Northern California Health Care System, CA, USA
    Am J Kidney Dis 47:166. 2006
    ..We hypothesized that the EPO dose-hematocrit (EPO/Hct) ratio, also known as the EPO index, may be a surrogate for inflammation and that greater EPO/Hct ratios would be associated with decreased survival...
  42. ncbi Cystatin C and mortality risk in the elderly: the health, aging, and body composition study
    Michael G Shlipak
    University of San Francisco, General Internal Medicine Section, VA Medical Center (111A1, 4150 Clement Street, San Francisco, CA 94121, USA
    J Am Soc Nephrol 17:254-61. 2006
    ..39], 0.95 [0.68 to 1.32], 1.11 [0.79 to 1.57], 1.16 [0.86 to 1.58]). Cystatin C is a strong, independent risk factor for mortality in the elderly. Future studies should investigate whether cystatin C has a role in clinical medicine...
  43. ncbi Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients
    Glenn M Chertow
    Division of Nephrology, Department of Medicine, University of California-San Francisco, San Francisco, CA, USA
    Kidney Int 62:245-52. 2002
    ..CONCLUSIONS: Compared with calcium-based phosphate binders, sevelamer is less likely to cause hypercalcemia, low levels of PTH, and progressive coronary and aortic calcification in hemodialysis patients...
  44. ncbi Validation of questionnaires to estimate physical activity and functioning in end-stage renal disease
    K L Johansen
    Division of Nephrology, San Francisco VA Medical Center, San Francisco, California 94121, USA
    Kidney Int 59:1121-7. 2001
    ..To assess the consequences of inactivity and the results of efforts to increase activity in the end-stage renal disease (ESRD) population, valid instruments to measure physical activity and physical functioning in this group are needed...
  45. ncbi Trends and outcomes associated with serum albumin concentration among incident dialysis patients in the United States
    George A Kaysen
    Division of Nephrology, Department of Medicine and Department of Biochemistry and Molecular Medicine, University of California at Davis, Davis, California, USA
    J Ren Nutr 18:323-31. 2008
    ..To explore whether changing demographics and practice patterns in dialysis have influenced serum albumin concentrations, we analyzed trends in serum albumin among incident patients on dialysis from 1995 through 2004...
  46. ncbi Health-related quality of life and estimates of utility in chronic kidney disease
    Irina Gorodetskaya
    Division of Nephrology, Department of Medicine, University of California San Francisco, San Francisco, CA 94118-1211, USA
    Kidney Int 68:2801-8. 2005
    ..CONCLUSION: Health-related quality of life and estimates of utility are distressingly low in persons with CKD. Self-reported outcomes should be considered when evaluating health policy decisions that affect this population...
  47. ncbi Effects of sevelamer and calcium-based phosphate binders on uric acid concentrations in patients undergoing hemodialysis: a randomized clinical trial
    Jay P Garg
    Department of Medicine Research, University of California-San Francisco, UCSF Laurel Heights Suite 430, 3333 California Street, San Francisco, CA 94118-1211, USA
    Arthritis Rheum 52:290-5. 2005
    ..02). CONCLUSION: In a randomized clinical trial comparing sevelamer and calcium-based phosphate binders, treatment with sevelamer was associated with a significant reduction in serum uric acid concentrations...
  48. ncbi Fetuin-A and change in body composition in older persons
    Joachim H Ix
    Division of Nephrology, Department of Medicine, and Division of Preventive Medicine, University of California San Diego, Veterans Affairs San Diego Healthcare System, San Diego, California 92161, USA
    J Clin Endocrinol Metab 94:4492-8. 2009
    ..Whether higher fetuin-A concentrations are associated with accumulation of adiposity over time is unknown...
  49. ncbi Cardiac calcification in adult hemodialysis patients. A link between end-stage renal disease and cardiovascular disease?
    Paolo Raggi
    Section of Cardiology, Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA
    J Am Coll Cardiol 39:695-701. 2002
    ..We sought to determine clinical and laboratory correlates of calcification of the coronary arteries (CAs), aorta and mitral and aortic valves in adult subjects with end-stage renal disease (ESRD) receiving hemodialysis...
  50. ncbi Are nutritional status indicators associated with mortality in the Hemodialysis (HEMO) Study?
    Johanna T Dwyer
    Tufts University School of Medicine and Friedman School of Nutrition Science and Policy, Boston, Massachusetts 02111, USA
    Kidney Int 68:1766-76. 2005
    ..The purpose of this study was to determine if indicators of nutritional status were associated with subsequent mortality in hemodialysis patients...
  51. ncbi Prevalence and correlates of cognitive impairment in hemodialysis patients: the Frequent Hemodialysis Network trials
    Manjula Kurella Tamura
    Division of Nephrology, Stanford University School of Medicine, Palo Alto, California 94304, USA
    Clin J Am Soc Nephrol 5:1429-38. 2010
    ..This study evaluated the prevalence of cognitive impairment and association with modifiable ESRD- and dialysis-associated factors in a large group of hemodialysis patients...
  52. ncbi Inflammation and dietary protein intake exert competing effects on serum albumin and creatinine in hemodialysis patients
    G A Kaysen
    Division of Nephrology, University of California, Davis, USA
    Kidney Int 60:333-40. 2001
    ..The net effects of inflammation and dietary protein intake on nutritional markers over time are unknown...
  53. ncbi Non-immunologic predictors of chronic renal allograft failure: data from the United Network of Organ Sharing
    G M Chertow
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Kidney Int Suppl 52:S48-51. 1995
    ..These findings may have important biomedical and health care policy implications...
  54. ncbi Systolic blood pressure and mortality in prevalent haemodialysis patients in the HEMO study
    T I Chang
    Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA 94304, USA
    J Hum Hypertens 25:98-105. 2011
    ..Randomized clinical trials are needed to define optimal blood pressure targets in the haemodialysis population...
  55. ncbi Potential antiatherogenic and anti-inflammatory properties of sevelamer in maintenance hemodialysis patients
    Emiliana Ferramosca
    Section of Cardiology, Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA
    Am Heart J 149:820-5. 2005
    ..01). CONCLUSIONS: Sevelamer leads to favorable changes in lipids and inflammatory markers with potentially useful antiatherogenic effects in hemodialysis patients...
  56. ncbi Serum blood urea nitrogen as an independent marker of subsequent mortality among patients with acute coronary syndromes and normal to mildly reduced glomerular filtration rates
    Ajay J Kirtane
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts
    J Am Coll Cardiol 45:1781-6. 2005
    ..CONCLUSIONS: Among patients with unstable coronary syndromes and predominantly normal or mildly reduced GFR, an elevated BUN is associated with increased mortality, independent of sCr-based estimates of GFR and other biomarkers...
  57. ncbi Nephrology consultation in acute renal failure: does timing matter?
    Ravindra L Mehta
    Division of Nephrology, Department of Medicine, University of California, San Diego, California, USA
    Am J Med 113:456-61. 2002
    ..The goals of this study were to identify correlates of the timing of nephrology consultation in acute renal failure, and to explore the relation between timing of consultation and outcomes...
  58. ncbi Diuretics, mortality, and nonrecovery of renal function in acute renal failure
    Ravindra L Mehta
    Division of Nephrology, University of California, San Diego, Medical Center, USA
    JAMA 288:2547-53. 2002
    ..In the absence of compelling contradictory data from a randomized, blinded clinical trial, the widespread use of diuretics in critically ill patients with acute renal failure should be discouraged...
  59. ncbi The case against calcium-based phosphate binders
    Sharon M Moe
    Department of Medicine, Indiana University School of Medicine, 1001 W 10th Street, OPW 526, Indianapolis, IN 46260, USA
    Clin J Am Soc Nephrol 1:697-703. 2006
    ..Therefore, calcium-based phosphate binders should be avoided in many, if not most, patients who are undergoing dialysis...
  60. ncbi The severity of secondary hyperparathyroidism in chronic renal insufficiency is GFR-dependent, race-dependent, and associated with cardiovascular disease
    Ian H De Boer
    Division of Nephrology, Department of Medicine, University of California San Francisco, 94118, USA
    J Am Soc Nephrol 13:2762-9. 2002
    ..0; 95% CI, 1.3 to 2.9 per unit natural log PTH) and not associated with other co-morbid conditions. These factors should be considered when screening and managing SHPT in CRI...
  61. ncbi Vitamin D deficiency and frailty in older Americans
    E R Wilhelm-Leen
    Department of Medicine, Stanford University School of Medicine, Palo Alto, CA 94304, USA
    J Intern Med 268:171-80. 2010
    ..Low serum concentrations of 25-hydroxyvitamin D are known to be associated with multiple chronic diseases such as cardiovascular disease and diabetes, in addition to all cause mortality...
  62. ncbi Cardiac arrest and sudden death in dialysis units
    J A Karnik
    Divisions of Nephrology, Moffitt-Long Hospitals and UCSF-Mt. Zion Medical Center, Department of Medicine, University of California, San Francisco, USA
    Kidney Int 60:350-7. 2001
    ..To reduce the risk of adverse cardiac events on hemodialysis, the dialysate prescription should be evaluated and modified on an ongoing basis, especially following hospitalization in high-risk patients...
  63. ncbi Birth weight and adult hypertension and obesity in women
    G C Curhan
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 94:1310-5. 1996
    ..Low birth weight has been associated with an increased risk of hypertension, and high birth weight has been associated with increased adult body mass index. Published studies on adults have included only a small number of women...
  64. ncbi Diagnosis, epidemiology and outcomes of acute kidney injury
    Sushrut S Waikar
    Renal Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Clin J Am Soc Nephrol 3:844-61. 2008
    ..This review summarizes the major epidemiologic studies of acute kidney injury and efforts to modernize the approach to its diagnosis...
  65. ncbi Management of acute kidney injury in the intensive care unit: a cost-effectiveness analysis of daily vs alternate-day hemodialysis
    Amar A Desai
    Division of Nephrology, Stanford University School of Medicine, 780 Welch Rd, Ste 106, Palo Alto, California 94304, USA
    Arch Intern Med 168:1761-7. 2008
    ....
  66. ncbi Comparison of methods for estimating glomerular filtration rate in critically ill patients with acute kidney injury
    Josee Bouchard
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, San Diego, CA, USA
    Nephrol Dial Transplant 25:102-7. 2010
    ....
  67. ncbi Atrial natriuretic factor in oliguric acute renal failure. Anaritide Acute Renal Failure Study Group
    J Lewis
    Division of Nephrology, Vanderbilt University Medical Center, Nashville, TN, USA
    Am J Kidney Dis 36:767-74. 2000
    ..6 versus 23.9 mm Hg; P < 0.001). This well-characterized population with oliguric acute renal failure had an overall high morbidity and mortality...
  68. ncbi Determinants of physical performance in ambulatory patients on hemodialysis
    K L Johansen
    Divisions of Nephrology, San Francisco VA Medical Center, San Francisco, California 94121, USA
    Kidney Int 60:1586-91. 2001
    ..Gait speed has not been evaluated as a predictor of these important outcomes in patients on hemodialysis, nor have the determinants of gait speed in the dialysis population been studied...
  69. ncbi Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury
    Kathleen D Liu
    Division of Nephrology, University of California, San Francisco, CA, USA
    Crit Care Med 35:2755-61. 2007
    ..To identify biological and clinical predictors of acute kidney injury in subjects with acute lung injury...
  70. ncbi Correlates and outcomes of dementia among dialysis patients: the Dialysis Outcomes and Practice Patterns Study
    Manjula Kurella
    Division of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94118 1211, USA
    Nephrol Dial Transplant 21:2543-8. 2006
    ..The goals of this study were to determine the prevalence, correlates and dialysis-related outcomes of dementia in an international sample of haemodialysis patients...
  71. ncbi Significance of frailty among dialysis patients
    Kirsten L Johansen
    Nephrology Section, San Francisco VA Medical Center, San Francisco, CA 94121, USA
    J Am Soc Nephrol 18:2960-7. 2007
  72. ncbi Low level of self-reported physical activity in ambulatory patients new to dialysis
    Kirsten L Johansen
    Medical Service, Nephrology Section, San Francisco VA Medical Center, Department of Medicine, University of California, San Francisco, California 94121, USA
    Kidney Int 78:1164-70. 2010
    ..Hence, physical activity is distressingly low among patients new to dialysis. Thus, strategies to enhance activity in these patients should be explored...
  73. ncbi Octogenarians and nonagenarians starting dialysis in the United States
    Manjula Kurella
    Division of Nephrology, University of California, San Francisco, CA 94118 1211, USA
    Ann Intern Med 146:177-83. 2007
    ....
  74. ncbi Renal function and heart failure risk in older black and white individuals: the Health, Aging, and Body Composition Study
    Kirsten Bibbins-Domingo
    Division of General Internal Medicine, San Francisco General Hospital, CA 94143 1364, USA
    Arch Intern Med 166:1396-402. 2006
    ..Our objective was to determine whether the association of chronic kidney disease with incident heart failure differs between blacks and whites...
  75. ncbi Nonrecovery of kidney function and death after acute on chronic renal failure
    Chi yuan Hsu
    Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Clin J Am Soc Nephrol 4:891-8. 2009
    ..Relatively little is known about clinical outcomes, especially long-term outcomes, among patients who have chronic kidney disease (CKD) and experience superimposed acute renal failure (ARF; acute on chronic renal failure)...
  76. ncbi Survival by dialysis modality in critically ill patients with acute kidney injury
    Kerry C Cho
    Division of Nephrology, Department of Medicine, University of California San Francisco, San Francisco, CA 94118, USA
    J Am Soc Nephrol 17:3132-8. 2006
    ..Larger, prospective, randomized clinical trials to compare CRRT and IHD in severe AKI are needed...
  77. ncbi Association of cystatin C with mortality, cardiovascular events, and incident heart failure among persons with coronary heart disease: data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, Box 0532, HSE 672, University of California at San Francisco, San Francisco, CA 94143 0532, USA
    Circulation 115:173-9. 2007
    ..Cystatin C is a novel and sensitive endogenous marker of kidney function. Whether cystatin C concentrations are associated with adverse events among ambulatory persons with CHD is unknown...
  78. ncbi Association of body size with health status in patients beginning dialysis
    Kirsten L Johansen
    Division of Nephrology, San Francisco VA Medical Center, San Francisco, CA 94121, USA
    Am J Clin Nutr 83:543-9. 2006
    ..Greater weight-for-height has been associated with prolonged survival in patients with end-stage renal disease (ESRD) but not in the general population. The association between body size and health status has not been carefully evaluated...
  79. ncbi Validation of the Kidney Disease Quality of Life (KDQOL) cognitive function subscale
    Manjula Kurella
    Division of Nephrology, Department of Medicine, University of California San Francisco, San Francisco, California 94118-1211, USA
    Kidney Int 66:2361-7. 2004
    ..KDQOL-CF screening followed by 3MS testing in selected individuals may prove to be an effective and efficient strategy for identifying cognitive impairment in patients with kidney disease...
  80. ncbi Influence of race on kidney transplant outcomes within and outside the Department of Veterans Affairs
    Harini A Chakkera
    Department of Medicine, Division of Nephrology, University of California, San Francisco, California, 94143 0532, USA
    J Am Soc Nephrol 16:269-77. 2005
    ..26 to 1.36). In conclusion, racial disparities in kidney transplant outcomes seem to persist even in a universal access-to-care system such as the VA. Reasons for worse outcomes among African Americans require further investigation...
  81. ncbi Increased prevalence of subclinical and clinical hypothyroidism in persons with chronic kidney disease
    Joan C Lo
    Divisions of Endocrinology and Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, California, USA
    Kidney Int 67:1047-52. 2005
    ..Previous studies have suggested a higher prevalence of thyroid abnormalities in persons with end-stage renal disease. However, little is known regarding the epidemiology of thyroid disorders in persons with less severe kidney dysfunction...
  82. ncbi Chronic kidney disease and cognitive function in older adults: findings from the chronic renal insufficiency cohort cognitive study
    Kristine Yaffe
    Department of Psychiatry, School of Medicine, University of California at San Francisco, San Francisco, California, USA
    J Am Geriatr Soc 58:338-45. 2010
    ....
  83. ncbi Chronic kidney disease and cognitive impairment in the elderly: the health, aging, and body composition study
    Manjula Kurella
    Division of Nephrology, University of California San Francisco, Laurel Heights, 3333 California Street, Suite 430, San Francisco, CA 94118 1211, USA
    J Am Soc Nephrol 16:2127-33. 2005
    ..Studies aimed at understanding the mechanism(s) responsible for cognitive impairment in CKD and efforts to interrupt this decline are warranted...
  84. ncbi Functional status of elderly adults before and after initiation of dialysis
    Manjula Kurella Tamura
    Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA 94304, USA
    N Engl J Med 361:1539-47. 2009
    ..It is unclear whether functional status before dialysis is maintained after the initiation of this therapy in elderly patients with end-stage renal disease (ESRD)...
  85. ncbi Spectrum of acute renal failure in the intensive care unit: the PICARD experience
    Ravindra L Mehta
    Division of Nephrology, Department of Medicine, University of California San Diego, San Diego, California, USA
    Kidney Int 66:1613-21. 2004
    ..There is wide variation across institutions in patient characteristics and practice patterns. These differences highlight the need for additional multicenter observational and interventional studies in ARF...
  86. ncbi Increased fluid intake does not augment capacity to lay down new collagen in nursing home residents at risk for pressure ulcers: a randomized, controlled clinical trial
    Nancy A Stotts
    Department of Physiological Nursing, University of California San Francisco, San Francisco, California, USA
    Wound Repair Regen 17:780-8. 2009
    ..Further work is needed to examine the relationship between fluid intake and hydration in nursing home residents as well as the role of hydration in pressure ulcer prevention...
  87. ncbi Association of body size with outcomes among patients beginning dialysis
    Kirsten L Johansen
    Division of Nephrology, University of California San Francisco, San Francisco, CA 94118 1211, USA
    Am J Clin Nutr 80:324-32. 2004
    ..These reports have generally not examined extremely high values of body mass index (BMI; in kg/m(2)), survival >1 y, or alternative measures of adiposity...
  88. ncbi Elevations of serum phosphorus and potassium in mild to moderate chronic renal insufficiency
    Chi yuan Hsu
    Division of Nephrology, University of California at San Francisco, San Francisco, CA 94143, USA
    Nephrol Dial Transplant 17:1419-25. 2002
    ..However, the extent of these changes and their magnitude in relation to renal function is not well defined, especially among individuals with mild to moderate chronic renal insufficiency (CRI)...
  89. ncbi Bone mineral density is not diminished by mild to moderate chronic renal insufficiency
    Chi yuan Hsu
    Division of Nephrology, Prevention Science Group, University of California, San Francisco, San Francisco, California 94143 0532, USA
    Kidney Int 61:1814-20. 2002
    ..Persons with mild to moderate chronic renal insufficiency (CRI) may have reduced bone mineral density (BMD) as a result of abnormalities in acid-base and vitamin D-parathyroid hormone homeostasis...
  90. ncbi Self-assessed sleep quality in chronic kidney disease
    Manjula Kurella
    Division of Nephrology, Department of Medicine Research, Moffitt-Long Hospitals, UCSF-Mt. Zion Medical Center, University of California San Francisco, UCSF Laurel Heights Suite 430, 3333 California Street, San Francisco, CA 94118-1211, USA
    Int Urol Nephrol 37:159-65. 2005
    ..01). CONCLUSIONS: Sleep complaints are common in persons with CKD and ESRD and may be associated with the severity of kidney disease...
  91. ncbi Issues in renal nutrition for persons from the former Soviet Union
    I Gorodetskaya
    Dialysis Unit, UCSF Mt Zion Medical Center, San Francisco, CA, USA
    J Ren Nutr 10:98-102. 2000
    ..This report highlights the dietary practices of this immigrant community and the need for ethnicity-specific renal nutrition recommendations in modern dialysis practice...
  92. ncbi Mechanisms underlying renoprotection during renin-angiotensin system blockade
    M W Taal
    Renal Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Am J Physiol Renal Physiol 280:F343-55. 2001
    ..During renin-angiotensin system inhibition, renoprotection is dependent on control of both SBP and UprV. Incomplete suppression of renal cytokine gene expression may also contribute to CRD progression...
  93. ncbi On the design and analysis of multicenter trials in acute renal failure
    G M Chertow
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Kidney Dis 30:S96-101. 1997
    ..Several lessons can be learned from these efforts. This article will briefly address issues in the design and analysis of clinical trials, focusing on elements of special interest to practitioners of renal medicine...
  94. ncbi The elderly patients on hemodialysis
    S Anand
    Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA, USA
    Minerva Urol Nefrol 62:87-101. 2010
    ..Key concepts of geriatrics frailty, dementia and palliative care are also discussed, as nephrologists frequently participate in decision-making directed toward balancing longevity, functional status and the burden of therapy...
  95. ncbi Suspected iron dextran-related adverse drug events in hemodialysis patients
    R Fletes
    Division of Nephrology, Moffitt-Long Hospitals, University of California, San Francisco, 94143-0532, USA
    Am J Kidney Dis 37:743-9. 2001
    ..In summary, serious adverse reactions to IV iron dextran are rare in clinical practice. The risk appears to depend on the specific formulation of IV iron dextran. Otherwise, iron dextran-related ADEs are difficult to predict...
  96. ncbi Neighborhood poverty and kidney transplantation among US Asians and Pacific Islanders with end-stage renal disease
    Y N Hall
    Department of Medicine, University of Washington, Seattle, WA, USA
    Am J Transplant 8:2402-9. 2008
    ..Our findings call for studies to identify cultural and local barriers to transplant among Asians and Pacific Islanders, particularly those residing in resource-poor neighborhoods...
  97. ncbi Correlates of acute renal failure in patients receiving parenteral amphotericin B
    D W Bates
    Division of General Medicine, and the Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Kidney Int 60:1452-9. 2001
    ..This study identified correlates of ARF in amphotericin B therapy and used them to develop clinical prediction rules...
  98. ncbi Clearance of Pneumocystis carinii cysts in acute P carinii pneumonia: assessment by serial sputum induction
    W J O'Donnell
    Pulmonary Critical Care Division, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Chest 114:1264-8. 1998
    ..To determine the feasibility of repeat sputum induction in acute Pneumocystis carinii pneumonia (PCP) and to define the rate of clearance of P carinii cysts from the respiratory tract of HIV-seropositive patients with acute PCP...
  99. ncbi Community-based incidence of acute renal failure
    C Y Hsu
    Department of Medicine, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Kidney Int 72:208-12. 2007
    ..Both dialysis-requiring and non-dialysis requiring ARFs are becoming more common. Our data underscore the public health importance of ARF...
  100. ncbi beta(2)-Microglobulin modified with advanced glycation end products delays monocyte apoptosis
    F F Hou
    Duke Institute of Renal Outcomes Research and Health Policy, Division of Nephrology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Kidney Int 59:990-1002. 2001
    ..CONCLUSIONS: These findings support a novel role for AGE-modified proteins such as AGE-beta(2)m that may contribute to the development of a local inflammatory response, with predominant accumulation of monocytes/macrophages, in DRA...
  101. ncbi Higher serum creatinine concentrations in black patients with chronic kidney disease: beyond nutritional status and body composition
    Joy Hsu
    Stanford University School of Medicine, Grant Building, S 161, Stanford, CA 94305 5114, USA
    Clin J Am Soc Nephrol 3:992-7. 2008
    ..These differences have been assumed to be largely related to race-related differences in body composition, especially muscle mass...

Research Grants2

  1. Hospital and Community Acquired Acute Renal Failure
    Glenn Chertow; Fiscal Year: 2006
    ..This study will efficiently inform the Nephrology community by providing a foundation of fundamental information (ARF definitions, incidence, consequences and costs) upon which a clinical trials network can be built. ..
  2. FREEDOM - Frequent Dialysis Outcomes & Markers Study
    Glenn Chertow; Fiscal Year: 2006
    ..We are committed to working cooperatively and constructively with the other CCC and Data Analysis Coordinating Center-regardless of the final agreed-upon protocol. ..