Mickie H Cheng
Affiliation: University of California
- Mechanisms and models of immune tolerance breakdown in the ovaryMickie H Cheng
Division of Endocrinology, Department of Medicine, UCSF Diabetes Center, 513 Parnassus Ave, HSW 1102 Box 0540, San Francisco, CA 94143, USA
Semin Reprod Med 29:308-16. 2011..Work in translational models continues to provide insight into mechanisms of disease pathogenesis that will allow more accurate diagnosis and, ultimately, improved interventions for women with aPOI...
- Autoimmune oophoritis with multiple molecular targets mitigated by transgenic expression of materNoriyuki Otsuka
University of California San Francisco Diabetes Center, San Francisco, California 94143, USA
Endocrinology 152:2465-73. 2011..As a known autoantigen in the human APS1 (autoimmune polyglandular syndrome type 1), which is associated with POI, MATER may represent a relevant target for future diagnostic and therapeutic clinical interventions...
- Insights into type 1 diabetes from the autoimmune polyendocrine syndromesMickie H Cheng
Diabetes Center, University of California San Francisco, San Francisco, California 94143, USA
Curr Opin Endocrinol Diabetes Obes 20:271-8. 2013..Here, we discuss the tolerance mechanisms of the autoimmune polyendocrine syndromes and their relevance to type 1 diabetes...
- Monogenic autoimmunityMickie H Cheng
Department of Medicine, Division of Endocrinology and Metabolism, University of California at San Francisco, San Francisco, California 94143, USA
Annu Rev Immunol 30:393-427. 2012..The continued study of rare variants in autoimmune disease will inform future investigations and treatments directed at rare and common autoimmune diseases alike...
- BPIFB1 is a lung-specific autoantigen associated with interstitial lung diseaseAnthony K Shum
Division of Pulmonary and Critical Care, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
Sci Transl Med 5:206ra139. 2013....
- What's new in the Aire?Mickie H Cheng
Diabetes Center, University of California San Francisco, San Francisco, CA 94143, USA
Trends Immunol 28:321-7. 2007..Recent characterization of Aire-targeted antigens continues to bear this out. Here, we review the current progress surrounding the role of Aire in central tolerance from a molecular, genetic and developmental basis...