Research Topics
Species | Iona ChengSummaryAffiliation: University of Hawaii Country: USA Publications
Research Grants
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Detail Information
Publications
IGF2R missense single-nucleotide polymorphisms and breast cancer risk: the multiethnic cohort studyIona Cheng
Epidemiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, Hawaii 96813, USA
Cancer Epidemiol Biomarkers Prev 18:1922-4. 2009..None of these missense SNPs were significantly associated with breast cancer risk. Our findings provide no evidence that missense SNPs in IGF2R influence breast cancer susceptibility..- Prostatitis, sexually transmitted diseases, and prostate cancer: the California Men's Health StudyIona Cheng
Epidemiology Program, Cancer Research Center of Hawai i, University of Hawai i, Honolulu, Hawai i, United States of America
PLoS ONE 5:e8736. 2010..While we cannot rule out the possible influence of incidental detection, future studies are warranted to further investigate the role of infectious agents related to prostatitis and STDs in prostate cancer development... 
Type 2 diabetes risk variants and colorectal cancer risk: the Multiethnic Cohort and PAGE studiesIona Cheng
Epidemiology Program, University of Hawaii Cancer Center, University of Hawaii, Honolulu, HI 96817, USA
Gut 60:1703-11. 2011..Diabetes has been positively associated with the risk of colorectal cancer. This study investigated whether recently established risk variants for diabetes also have effects on colorectal cancer...- Susceptibility variants for obesity and colorectal cancer risk: the multiethnic cohort and PAGE studiesUnhee Lim
Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA
Int J Cancer 131:E1038-43. 2012..No heterogeneity was observed across race/ethnic groups. Our findings suggest that the obesity risk variants are not likely to affect the risk of colorectal cancer substantially... - IGF1, IGFBP1, and IGFBP3 genes and mammographic density: the Multiethnic CohortMartijn Verheus
Epidemiology Program, Cancer Research Center of Hawaii, Honolulu, HI
Int J Cancer 127:1115-23. 2010..Given the large number of SNPs tested and the few borderline significant results, we only found weak evidence that genetic variations in IGFBP1 or IGFBP3 may be related to mammographic density. Ethnicity may modify these relations... - Susceptibility variants for waist size in relation to abdominal, visceral, and hepatic adiposity in postmenopausal womenUnhee Lim
Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA
J Acad Nutr Diet 112:1048-55. 2012..If replicated, these genetic variants can be incorporated with other biomarkers to predict high-risk body fat distribution... - Genetic variants, prediagnostic circulating levels of insulin-like growth factors, insulin, and glucose and the risk of colorectal cancer: the Multiethnic Cohort studyNicholas J Ollberding
University of Hawaii Cancer Center, Epidemiology Program, Honolulu, Hawaii 96813, USA
Cancer Epidemiol Biomarkers Prev 21:810-20. 2012..Increased exposure of colonic and rectal epithelial cells to the promitotic and antiapoptotic effects of insulin and insulin-like growth factors (IGF) is hypothesized to increase colorectal cancer risk... - Copy number alterations in prostate tumors and disease aggressivenessIona Cheng
Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA
Genes Chromosomes Cancer 51:66-76. 2012..007). These findings confirm known regions of CNAs in prostate cancer and localize additional regions and possible genes (e.g., BNIP3L, WWOX, and GATM) that may help to clarify the genetic basis of prostate cancer aggressiveness... - cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissueLenora W M Loo
Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, United States of America
PLoS ONE 7:e30477. 2012.... - Prostate cancer susceptibility variants confer increased risk of disease progressionIona Cheng
Epidemiology Program, Cancer Research Center of Hawai i, University of Hawai i, Honolulu, Hawaii, USA
Cancer Epidemiol Biomarkers Prev 19:2124-32. 2010..Genome-wide association studies have identified numerous single nucleotide polymorphisms (SNP) associated with the risk of prostate cancer. Our objective was to determine whether these SNPs affect the progression of prostate cancer... - Measurement of circulating cell-free DNA in relation to 18F-fluorocholine PET/CT imaging in chemotherapy-treated advanced prostate cancerSANDI KWEE
The University of Hawaii Cancer Center, Honolulu, HI, USA
Clin Transl Sci 5:65-70. 2012.... - Examining the association between socioeconomic status and invasive colorectal cancer incidence and mortality in CaliforniaAstrid Steinbrecher
Epidemiology Program, University of Hawai i Cancer Center, University of Hawai i, Honolulu, Hawaii 96813, USA
Cancer Epidemiol Biomarkers Prev 21:1814-22. 2012..We examined associations between area-level SES and CRC incidence and mortality in a population-based registry study of non-Hispanic Whites, African Americans, Hispanics, and Asians/Pacific Islanders from California... - Evaluating genetic risk for prostate cancer among Japanese and LatinosIona Cheng
Epidemiology Program, University of Hawaii Cancer Center, 1236 Lauhala Street, Suite 407, Honolulu, HI 96813, USA
Cancer Epidemiol Biomarkers Prev 21:2048-58. 2012..In addition, we tested prostate cancer risk variants and developed genetic risk models of prostate cancer for Japanese and Latinos...
Research Grants
- Characterizing Mitochondrial DNA Susceptibility to Breast, Colorectal, and ProstaIona Cheng; Fiscal Year: 2009..In addition, we will evaluate heterogeneity of effects by disease sub-groups, environmental factors and known genetic risk factors. ..
- Characterizing Mitochondrial DNA Susceptibility to Breast, Colorectal, and ProstaIona Cheng; Fiscal Year: 2010..In addition, we will evaluate heterogeneity of effects by disease sub-groups, environmental factors and known genetic risk factors. ..