Iona Cheng

Summary

Affiliation: University of Hawaii
Country: USA

Publications

  1. pmc IGF2R missense single-nucleotide polymorphisms and breast cancer risk: the multiethnic cohort study
    Iona Cheng
    Epidemiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, Hawaii 96813, USA
    Cancer Epidemiol Biomarkers Prev 18:1922-4. 2009
  2. pmc Prostatitis, sexually transmitted diseases, and prostate cancer: the California Men's Health Study
    Iona Cheng
    Epidemiology Program, Cancer Research Center of Hawai i, University of Hawai i, Honolulu, Hawai i, United States of America
    PLoS ONE 5:e8736. 2010
  3. doi request reprint Type 2 diabetes risk variants and colorectal cancer risk: the Multiethnic Cohort and PAGE studies
    Iona Cheng
    Epidemiology Program, University of Hawaii Cancer Center, University of Hawaii, Honolulu, HI 96817, USA
    Gut 60:1703-11. 2011
  4. pmc Susceptibility variants for obesity and colorectal cancer risk: the multiethnic cohort and PAGE studies
    Unhee Lim
    Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA
    Int J Cancer 131:E1038-43. 2012
  5. pmc Association of the FTO obesity risk variant rs8050136 with percentage of energy intake from fat in multiple racial/ethnic populations: the PAGE study
    Sungshim Lani Park
    Epidemiology Program, University of Hawaii Cancer Center, 701 Ilalo Street, Honolulu, HI 96813, USA
    Am J Epidemiol 178:780-90. 2013
  6. doi request reprint Integrated analysis of genome-wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype-negative colon cancer
    Lenora W M Loo
    Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA
    Genes Chromosomes Cancer 52:450-66. 2013
  7. pmc IGF1, IGFBP1, and IGFBP3 genes and mammographic density: the Multiethnic Cohort
    Martijn Verheus
    Epidemiology Program, Cancer Research Center of Hawaii, Honolulu, HI
    Int J Cancer 127:1115-23. 2010
  8. pmc Evaluating genetic risk for prostate cancer among Japanese and Latinos
    Iona Cheng
    Epidemiology Program, University of Hawaii Cancer Center, 1236 Lauhala Street, Suite 407, Honolulu, HI 96813, USA
    Cancer Epidemiol Biomarkers Prev 21:2048-58. 2012
  9. pmc Susceptibility variants for waist size in relation to abdominal, visceral, and hepatic adiposity in postmenopausal women
    Unhee Lim
    Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA
    J Acad Nutr Diet 112:1048-55. 2012
  10. doi request reprint Genetic variants, prediagnostic circulating levels of insulin-like growth factors, insulin, and glucose and the risk of colorectal cancer: the Multiethnic Cohort study
    Nicholas J Ollberding
    University of Hawaii Cancer Center, Epidemiology Program, Honolulu, Hawaii 96813, USA
    Cancer Epidemiol Biomarkers Prev 21:810-20. 2012

Detail Information

Publications15

  1. pmc IGF2R missense single-nucleotide polymorphisms and breast cancer risk: the multiethnic cohort study
    Iona Cheng
    Epidemiology Program, Cancer Research Center of Hawaii, University of Hawaii, Honolulu, Hawaii 96813, USA
    Cancer Epidemiol Biomarkers Prev 18:1922-4. 2009
    ..None of these missense SNPs were significantly associated with breast cancer risk. Our findings provide no evidence that missense SNPs in IGF2R influence breast cancer susceptibility..
  2. pmc Prostatitis, sexually transmitted diseases, and prostate cancer: the California Men's Health Study
    Iona Cheng
    Epidemiology Program, Cancer Research Center of Hawai i, University of Hawai i, Honolulu, Hawai i, United States of America
    PLoS ONE 5:e8736. 2010
    ..43; 95% CI: 1.07-1.91). Interestingly, foreign-born Latinos displayed a larger risk associated with STDs (RR = 1.87; 95% CI: 1.16-3.02) than U.S. born Latinos (RR = 1.15; 95% CI: 0.76-3.02)...
  3. doi request reprint Type 2 diabetes risk variants and colorectal cancer risk: the Multiethnic Cohort and PAGE studies
    Iona Cheng
    Epidemiology Program, University of Hawaii Cancer Center, University of Hawaii, Honolulu, HI 96817, USA
    Gut 60:1703-11. 2011
    ..Diabetes has been positively associated with the risk of colorectal cancer. This study investigated whether recently established risk variants for diabetes also have effects on colorectal cancer...
  4. pmc Susceptibility variants for obesity and colorectal cancer risk: the multiethnic cohort and PAGE studies
    Unhee Lim
    Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA
    Int J Cancer 131:E1038-43. 2012
    ..No heterogeneity was observed across race/ethnic groups. Our findings suggest that the obesity risk variants are not likely to affect the risk of colorectal cancer substantially...
  5. pmc Association of the FTO obesity risk variant rs8050136 with percentage of energy intake from fat in multiple racial/ethnic populations: the PAGE study
    Sungshim Lani Park
    Epidemiology Program, University of Hawaii Cancer Center, 701 Ilalo Street, Honolulu, HI 96813, USA
    Am J Epidemiol 178:780-90. 2013
    ..0823 kg/m(2), 95% confidence interval: 0.0559, 0.1128). Our data provide additional evidence that the association of FTO with obesity is partially mediated by dietary intake. ..
  6. doi request reprint Integrated analysis of genome-wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype-negative colon cancer
    Lenora W M Loo
    Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA
    Genes Chromosomes Cancer 52:450-66. 2013
    ..The results from our integration analysis illustrate the complex relationship between genomic alterations and gene expression in colon cancer...
  7. pmc IGF1, IGFBP1, and IGFBP3 genes and mammographic density: the Multiethnic Cohort
    Martijn Verheus
    Epidemiology Program, Cancer Research Center of Hawaii, Honolulu, HI
    Int J Cancer 127:1115-23. 2010
    ..Given the large number of SNPs tested and the few borderline significant results, we only found weak evidence that genetic variations in IGFBP1 or IGFBP3 may be related to mammographic density. Ethnicity may modify these relations...
  8. pmc Evaluating genetic risk for prostate cancer among Japanese and Latinos
    Iona Cheng
    Epidemiology Program, University of Hawaii Cancer Center, 1236 Lauhala Street, Suite 407, Honolulu, HI 96813, USA
    Cancer Epidemiol Biomarkers Prev 21:2048-58. 2012
    ..In addition, we tested prostate cancer risk variants and developed genetic risk models of prostate cancer for Japanese and Latinos...
  9. pmc Susceptibility variants for waist size in relation to abdominal, visceral, and hepatic adiposity in postmenopausal women
    Unhee Lim
    Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA
    J Acad Nutr Diet 112:1048-55. 2012
    ..If replicated, these genetic variants can be incorporated with other biomarkers to predict high-risk body fat distribution...
  10. doi request reprint Genetic variants, prediagnostic circulating levels of insulin-like growth factors, insulin, and glucose and the risk of colorectal cancer: the Multiethnic Cohort study
    Nicholas J Ollberding
    University of Hawaii Cancer Center, Epidemiology Program, Honolulu, Hawaii 96813, USA
    Cancer Epidemiol Biomarkers Prev 21:810-20. 2012
    ..Increased exposure of colonic and rectal epithelial cells to the promitotic and antiapoptotic effects of insulin and insulin-like growth factors (IGF) is hypothesized to increase colorectal cancer risk...
  11. pmc Copy number alterations in prostate tumors and disease aggressiveness
    Iona Cheng
    Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA
    Genes Chromosomes Cancer 51:66-76. 2012
    ..007). These findings confirm known regions of CNAs in prostate cancer and localize additional regions and possible genes (e.g., BNIP3L, WWOX, and GATM) that may help to clarify the genetic basis of prostate cancer aggressiveness...
  12. pmc cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue
    Lenora W M Loo
    Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, United States of America
    PLoS ONE 7:e30477. 2012
    ....
  13. pmc Prostate cancer susceptibility variants confer increased risk of disease progression
    Iona Cheng
    Epidemiology Program, Cancer Research Center of Hawai i, University of Hawai i, Honolulu, Hawaii, USA
    Cancer Epidemiol Biomarkers Prev 19:2124-32. 2010
    ..Genome-wide association studies have identified numerous single nucleotide polymorphisms (SNP) associated with the risk of prostate cancer. Our objective was to determine whether these SNPs affect the progression of prostate cancer...
  14. pmc Measurement of circulating cell-free DNA in relation to 18F-fluorocholine PET/CT imaging in chemotherapy-treated advanced prostate cancer
    SANDI KWEE
    The University of Hawaii Cancer Center, Honolulu, HI, USA
    Clin Transl Sci 5:65-70. 2012
    ....
  15. doi request reprint Examining the association between socioeconomic status and invasive colorectal cancer incidence and mortality in California
    Astrid Steinbrecher
    Epidemiology Program, University of Hawai i Cancer Center, University of Hawai i, Honolulu, Hawaii 96813, USA
    Cancer Epidemiol Biomarkers Prev 21:1814-22. 2012
    ..We examined associations between area-level SES and CRC incidence and mortality in a population-based registry study of non-Hispanic Whites, African Americans, Hispanics, and Asians/Pacific Islanders from California...

Research Grants2

  1. Characterizing Mitochondrial DNA Susceptibility to Breast, Colorectal, and Prosta
    Iona Cheng; Fiscal Year: 2009
    ..In addition, we will evaluate heterogeneity of effects by disease sub-groups, environmental factors and known genetic risk factors. ..
  2. Characterizing Mitochondrial DNA Susceptibility to Breast, Colorectal, and Prosta
    Iona Cheng; Fiscal Year: 2010
    ..In addition, we will evaluate heterogeneity of effects by disease sub-groups, environmental factors and known genetic risk factors. ..