Iona Cheng

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort
    Iona Cheng
    Department of Epidemiology and Biostatistics and Center for Human Genetics, University of California San Francisco, San Francisco, California, USA
    Cancer Epidemiol Biomarkers Prev 15:1993-7. 2006
  2. pmc Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res 9:R18. 2007
  3. pmc A comprehensive analysis of common genetic variation in prolactin (PRL) and PRL receptor (PRLR) genes in relation to plasma prolactin levels and breast cancer risk: the multiethnic cohort
    Sulggi A Lee
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA, USA
    BMC Med Genet 8:72. 2007
  4. ncbi Genetic determinants of circulating insulin-like growth factor (IGF)-I, IGF binding protein (BP)-1, and IGFBP-3 levels in a multiethnic population
    Iona Cheng
    Department of Epidemiology and Biostatistics, University of California, San Francisco, California 94143 0794, USA
    J Clin Endocrinol Metab 92:3660-6. 2007
  5. pmc Socioeconomic status and prostate cancer incidence and mortality rates among the diverse population of California
    Iona Cheng
    Department of Epidemiology and Biostatistics and Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94143 0794, USA
    Cancer Causes Control 20:1431-40. 2009
  6. pmc Carboxypeptidase 4 gene variants and early-onset intermediate-to-high risk prostate cancer
    Phillip L Ross
    Department of Urology, University of California San Francisco, San Francisco, CA, USA
    BMC Cancer 9:69. 2009
  7. pmc 8q24 and prostate cancer: association with advanced disease and meta-analysis
    Iona Cheng
    Department of Epidemiology and Biostatistics and Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94143 0794, USA
    Eur J Hum Genet 16:496-505. 2008
  8. pmc Dietary omega-3 fatty acids, cyclooxygenase-2 genetic variation, and aggressive prostate cancer risk
    Vincent Fradet
    Departments of Urology, Institute for Human Genetics, University of California at San Francisco, San Francisco, California 94143 0794, USA
    Clin Cancer Res 15:2559-66. 2009
  9. pmc Association of the innate immunity and inflammation pathway with advanced prostate cancer risk
    Rémi Kazma
    Department of Epidemiology, and Institute for Human Genetics, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 7:e51680. 2012
  10. ncbi MIC1 and IL1RN genetic variation and advanced prostate cancer risk
    Iona Cheng
    Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94143 0794, USA
    Cancer Epidemiol Biomarkers Prev 16:1309-11. 2007

Detail Information

Publications21

  1. ncbi Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort
    Iona Cheng
    Department of Epidemiology and Biostatistics and Center for Human Genetics, University of California San Francisco, San Francisco, California, USA
    Cancer Epidemiol Biomarkers Prev 15:1993-7. 2006
    ..Our results suggest that common genetic variation in the IGFBP1 and IGFBP3 genes do not substantially influence prostate and breast cancer susceptibility...
  2. pmc Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res 9:R18. 2007
    ....
  3. pmc A comprehensive analysis of common genetic variation in prolactin (PRL) and PRL receptor (PRLR) genes in relation to plasma prolactin levels and breast cancer risk: the multiethnic cohort
    Sulggi A Lee
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, CA, USA
    BMC Med Genet 8:72. 2007
    ..Prospective epidemiological studies have also shown that women with higher circulating PRL levels have an increase in risk of breast cancer, suggesting that variability in PRL may also be important in determining a woman's risk...
  4. ncbi Genetic determinants of circulating insulin-like growth factor (IGF)-I, IGF binding protein (BP)-1, and IGFBP-3 levels in a multiethnic population
    Iona Cheng
    Department of Epidemiology and Biostatistics, University of California, San Francisco, California 94143 0794, USA
    J Clin Endocrinol Metab 92:3660-6. 2007
    ..Both circulating levels and genetic variation of IGFs have been associated with cancer risk, yet the relationship between the two is not well understood...
  5. pmc Socioeconomic status and prostate cancer incidence and mortality rates among the diverse population of California
    Iona Cheng
    Department of Epidemiology and Biostatistics and Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94143 0794, USA
    Cancer Causes Control 20:1431-40. 2009
    ..Furthermore, previous studies have focused primarily on the differences between African-Americans and non-Hispanic Whites, and little is known for Hispanics and Asian/Pacific Islanders...
  6. pmc Carboxypeptidase 4 gene variants and early-onset intermediate-to-high risk prostate cancer
    Phillip L Ross
    Department of Urology, University of California San Francisco, San Francisco, CA, USA
    BMC Cancer 9:69. 2009
    ..We examined the association between genetic variation in CPA4 and intermediate-to-high risk prostate cancer...
  7. pmc 8q24 and prostate cancer: association with advanced disease and meta-analysis
    Iona Cheng
    Department of Epidemiology and Biostatistics and Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94143 0794, USA
    Eur J Hum Genet 16:496-505. 2008
    ..Our findings provide the first confirmation that the three 8q24 regions independently influence the risk of prostate cancer and, in particular, advanced disease...
  8. pmc Dietary omega-3 fatty acids, cyclooxygenase-2 genetic variation, and aggressive prostate cancer risk
    Vincent Fradet
    Departments of Urology, Institute for Human Genetics, University of California at San Francisco, San Francisco, California 94143 0794, USA
    Clin Cancer Res 15:2559-66. 2009
    ..This potential effect may be modified by genetic variation in cyclooxygenase-2 (COX-2), a key enzyme in fatty acid metabolism and inflammation...
  9. pmc Association of the innate immunity and inflammation pathway with advanced prostate cancer risk
    Rémi Kazma
    Department of Epidemiology, and Institute for Human Genetics, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 7:e51680. 2012
    ..Our results suggest that the innate immunity and inflammation pathway may play a modest role in the etiology of advanced prostate cancer through multiple small effects...
  10. ncbi MIC1 and IL1RN genetic variation and advanced prostate cancer risk
    Iona Cheng
    Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94143 0794, USA
    Cancer Epidemiol Biomarkers Prev 16:1309-11. 2007
  11. pmc Impact of consumption of vegetable, fruit, grain, and high glycemic index foods on aggressive prostate cancer risk
    Jill Hardin
    Department of Epidemiology, University of California at San Francisco, San Francisco, California 94158 9001, USA
    Nutr Cancer 63:860-72. 2011
    ..02). These results were driven by a number of specific foods within the food groups. Our findings support the hypothesis that diets high in vegetables and low in high glycemic index foods decrease risk of aggressive prostate cancer...
  12. pmc Genome-wide association studies and cancer
    Eric Jorgenson
    Department of Neurology, Ernest Gallo Clinic and Research Center at the University of California, San Francisco, Emeryville, CA 94608, USA
    Hawaii Med J 69:249-51. 2010
  13. doi The role of genetic variation in Toll-like receptor 4 in prostate cancer susceptibility: a review
    Iona Cheng
    University of California, Department of Epidemiology and Biostatistics, Institute of Human Genetics, San Francisco, CA 94143 0794, USA 1 415 502 6882 1 415 476 1356
    Expert Opin Med Diagn 2:143-9. 2008
    ....
  14. ncbi Common genetic variation in IGF1 and prostate cancer risk in the Multiethnic Cohort
    Iona Cheng
    Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    J Natl Cancer Inst 98:123-34. 2006
    ..Insulin-like growth factor I (IGF-I) appears to play a role in prostate development and carcinogenesis. We investigated whether genetic variation at the IGF1 locus is associated with prostate cancer risk...
  15. ncbi Igf-I genetic variation and breast cancer: the multiethnic cohort
    Veronica Wendy Setiawan
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Cancer Epidemiol Biomarkers Prev 15:172-4. 2006
  16. ncbi Common genetic variation at PTEN and risk of sporadic breast and prostate cancer
    Christopher A Haiman
    University of Southern California Norris Comprehensive Cancer Center, Room 4441, 1441 Eastlake Avenue, Los Angeles, CA 90089 9175, USA
    Cancer Epidemiol Biomarkers Prev 15:1021-5. 2006
    ..We found no strong association with any common haplotype in relation to breast or prostate cancer risk. In summary, our results show that common variants in PTEN do not substantially influence risk of these two common cancers...
  17. pmc IGF-1, IGFBP-1, and IGFBP-3 polymorphisms predict circulating IGF levels but not breast cancer risk: findings from the Breast and Prostate Cancer Cohort Consortium (BPC3)
    Alpa V Patel
    Department of Epidemiology and Surveillance Research, American Cancer Society, Atlanta, Georgia, United States of America
    PLoS ONE 3:e2578. 2008
    ..In summary, the impact of genetic variation in IGF1 and IGFBP3 on circulating IGF levels does not appear to substantially influence breast cancer risk substantially among primarily Caucasian postmenopausal women...
  18. ncbi A systematic assessment of common genetic variation in CYP11A and risk of breast cancer
    Veronica Wendy Setiawan
    Departments of Preventive Medicine and Urology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Cancer Res 66:12019-25. 2006
    ..Based on these findings, CYP11A deserves further consideration as a candidate breast cancer susceptibility gene...
  19. ncbi Toll-like receptor 4 genetic variation and advanced prostate cancer risk
    Iona Cheng
    Department of Epidemiology and Biostatistics and Center of Human Genetics, University of California at San Francisco, 94143 0794, USA
    Cancer Epidemiol Biomarkers Prev 16:352-5. 2007
    ..006). We estimated through permutation analysis that a similarly strong result would occur by chance 2.5% of the time. Our findings support previous studies and suggest that inherited differences in TLR4 influence prostate cancer risk...
  20. ncbi Comparison of prostate-specific antigen and hormone levels among men in Singapore and the United States
    Iona Cheng
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, USC Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA, 90089 9175, USA
    Cancer Epidemiol Biomarkers Prev 14:1692-6. 2005
    ..Given that the overall mortality rate of prostate cancer in Singapore is low, these undiagnosed cancers may be of nonaggressive type. Alternatively, PSA may be a poor marker of prostate cancer in this low-risk population...
  21. ncbi Polymorphisms in the androgen receptor and type II 5 alpha-reductase genes and prostate cancer prognosis
    Atsuko Shibata
    Department of Health Research and Policy, Stanford University School of Medicine, Stanford, California 94305 5405, USA
    Prostate 52:269-78. 2002
    ..Cytosine-adenine-guanine repeat length of the androgen receptor gene and the A49T and V89L polymorphisms of the 5 alpha-reductase (SRD5A2) gene have been associated with prostate cancer...