Hsinlin T Cheng

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. doi Increased axonal regeneration and swellings in intraepidermal nerve fibers characterize painful phenotypes of diabetic neuropathy
    Hsinlin T Cheng
    Department of Neurology, University of Michigan Medical Center, Ann Arbor, Michigan 48109 2200, USA
    J Pain 14:941-7. 2013
  2. pmc Nerve growth factor/p38 signaling increases intraepidermal nerve fiber densities in painful neuropathy of type 2 diabetes
    Hsinlin T Cheng
    Department of Neurology, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
    Neurobiol Dis 45:280-7. 2012
  3. pmc Inflammatory pain-induced signaling events following a conditional deletion of the N-methyl-D-aspartate receptor in spinal cord dorsal horn
    H T Cheng
    Department of Pharmacology, Weill Medical College, Cornell University, New York, NY 10065, USA
    Neuroscience 155:948-58. 2008
  4. pmc Nerve growth factor mediates mechanical allodynia in a mouse model of type 2 diabetes
    Hsinlin T Cheng
    Department of Neurology, University of Michigan Medical Center, Ann Arbor, Michigan 48109 2200, USA
    J Neuropathol Exp Neurol 68:1229-43. 2009
  5. pmc Spinal cord mechanisms of chronic pain and clinical implications
    Hsinlin Thomas Cheng
    Department of Neurology, University of Michigan, 109 Zina Pitcher Place, 5015 BSRB, Ann Arbor, MI 48109, USA
    Curr Pain Headache Rep 14:213-20. 2010
  6. pmc p38 mediates mechanical allodynia in a mouse model of type 2 diabetes
    Hsinlin T Cheng
    Department of Neurology, University of Michigan Medical Center, Ann Arbor, Michigan, USA
    Mol Pain 6:28. 2010
  7. pmc Neuron-astrocyte signaling network in spinal cord dorsal horn mediates painful neuropathy of type 2 diabetes
    Jacqueline R Dauch
    Department of Neurology, University of Michigan Medical Center, Ann Arbor, MI 48109 2200, USA
    Glia 60:1301-15. 2012
  8. pmc Neurogenic factor-induced Langerhans cell activation in diabetic mice with mechanical allodynia
    Jacqueline R Dauch
    Department of Neurology, University of Michigan Medical Center, Ann Arbor, MI, USA
    J Neuroinflammation 10:64. 2013
  9. doi Diabetic neuropathy: clinical manifestations and current treatments
    Brian C Callaghan
    University of Michigan, Ann Arbor, MI, USA
    Lancet Neurol 11:521-34. 2012

Collaborators

Detail Information

Publications9

  1. doi Increased axonal regeneration and swellings in intraepidermal nerve fibers characterize painful phenotypes of diabetic neuropathy
    Hsinlin T Cheng
    Department of Neurology, University of Michigan Medical Center, Ann Arbor, Michigan 48109 2200, USA
    J Pain 14:941-7. 2013
    ..These axonal swellings were positive for tropomyosin-receptor-kinase A and substance P, suggesting that they are associated with nociception...
  2. pmc Nerve growth factor/p38 signaling increases intraepidermal nerve fiber densities in painful neuropathy of type 2 diabetes
    Hsinlin T Cheng
    Department of Neurology, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
    Neurobiol Dis 45:280-7. 2012
    ..Furthermore, the inhibition of NGF-p38 signaling could be a potential therapeutic strategy for treating this painful condition...
  3. pmc Inflammatory pain-induced signaling events following a conditional deletion of the N-methyl-D-aspartate receptor in spinal cord dorsal horn
    H T Cheng
    Department of Pharmacology, Weill Medical College, Cornell University, New York, NY 10065, USA
    Neuroscience 155:948-58. 2008
    ..Our findings provide evidence that inflammatory reactions are responsible for the recurrence of pain after NR1 KO in the SCDH...
  4. pmc Nerve growth factor mediates mechanical allodynia in a mouse model of type 2 diabetes
    Hsinlin T Cheng
    Department of Neurology, University of Michigan Medical Center, Ann Arbor, Michigan 48109 2200, USA
    J Neuropathol Exp Neurol 68:1229-43. 2009
    ..These results suggest that inhibition of NGF action is a potential strategy for treating painful diabetic neuropathy...
  5. pmc Spinal cord mechanisms of chronic pain and clinical implications
    Hsinlin Thomas Cheng
    Department of Neurology, University of Michigan, 109 Zina Pitcher Place, 5015 BSRB, Ann Arbor, MI 48109, USA
    Curr Pain Headache Rep 14:213-20. 2010
    ..In this review, the molecular events associated with central sensitization, as well as their clinical implications, are discussed...
  6. pmc p38 mediates mechanical allodynia in a mouse model of type 2 diabetes
    Hsinlin T Cheng
    Department of Neurology, University of Michigan Medical Center, Ann Arbor, Michigan, USA
    Mol Pain 6:28. 2010
    ..Using this timeline of PDN, we can investigate the signaling mechanisms underlying mechanical allodynia in the db/db mouse...
  7. pmc Neuron-astrocyte signaling network in spinal cord dorsal horn mediates painful neuropathy of type 2 diabetes
    Jacqueline R Dauch
    Department of Neurology, University of Michigan Medical Center, Ann Arbor, MI 48109 2200, USA
    Glia 60:1301-15. 2012
    ..These results suggest that nitric oxide from surrounding interneurons and astrocytes interacts with NMDAR-dependent signaling in the projection neurons of the SCDH during the maintenance of PDN...
  8. pmc Neurogenic factor-induced Langerhans cell activation in diabetic mice with mechanical allodynia
    Jacqueline R Dauch
    Department of Neurology, University of Michigan Medical Center, Ann Arbor, MI, USA
    J Neuroinflammation 10:64. 2013
    ..Langerhans cells (LCs) are antigen-presenting dendritic cells located in the skin. It has been reported that LC activation is associated with painful diabetic neuropathy (PDN); however, the mechanism of LC activation is still unclear...
  9. doi Diabetic neuropathy: clinical manifestations and current treatments
    Brian C Callaghan
    University of Michigan, Ann Arbor, MI, USA
    Lancet Neurol 11:521-34. 2012
    ..Studies are needed to further explore this association, which has implications for the development of new treatments for this common disorder...