Research Topics
| Zhao ChenSummaryAffiliation: University of Arizona Country: USA Publications
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Publications
Habitual tea consumption and risk of osteoporosis: a prospective study in the women's health initiative observational cohortZ Chen
Arizona College of Public Health, University of Arizona, Tucson, AZ 85716, USA
Am J Epidemiol 158:772-81. 2003..In conclusion, the results from this study indicate that the effect of habitual tea drinking on bone density is small and does not significantly alter the risk of fractures among the US postmenopausal population...
Hormone therapy improves femur geometry among ethnically diverse postmenopausal participants in the Women's Health Initiative hormone intervention trialsZhao Chen
Division of Epidemiology and Biostatistics, University of Arizona, Tucson, Arizona 85724 5211, USA
J Bone Miner Res 23:1935-45. 2008..3-3.6% for section modulus and -5.3% to - 4.3% for buckling ratio. Hormone interventions led to favorable changes in femur geometry, which may help explain the reduced fracture risk observed in hormone interventions...
Hip bone density predicts breast cancer risk independently of Gail score: results from the Women's Health InitiativeZhao Chen
Division of Epidemiology and Biostatistics, University of Arizona College of Public Health, Tucson, Arizona 85724 5211, USA
Cancer 113:907-15. 2008..The objective of the current study was to investigate whether hip BMD predicts postmenopausal breast cancer risk independently of the Gail score...
Fracture risk increases after diagnosis of breast or other cancers in postmenopausal women: results from the Women's Health InitiativeZ Chen
Division of Epidemiology and Biostatistics, University of Arizona Mel and Enid Zuckerman College of Public Health, Tucson, AZ 85724 5211, USA
Osteoporos Int 20:527-36. 2009..Risk for falls and fractures increases after breast cancer or other cancer diagnosis in postmenopausal women. Factors other than falls may be the major causes for the increased fracture risk...
Postmenopausal hormone therapy and body composition--a substudy of the estrogen plus progestin trial of the Women's Health InitiativeZhao Chen
Division of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ 85724, USA
Am J Clin Nutr 82:651-6. 2005..It has been suggested that hormone therapy may help counter undesirable changes in body composition in older women...
Osteoporosis and rate of bone loss among postmenopausal survivors of breast cancerZhao Chen
Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona 85724, USA
Cancer 104:1520-30. 2005..Breast cancer diagnosis and treatment may put women at higher risk for osteoporosis in later life...
Dual-energy X-ray absorptiometry is a valid tool for assessing skeletal muscle mass in older womenZhao Chen
College of Public Health, University of Arizona, Tucson, AZ 85724, USA
J Nutr 137:2775-80. 2007..We conclude that DXA is a reliable method for cross-sectional assessments of SMM in older women...
Fracture risk among breast cancer survivors: results from the Women's Health Initiative Observational StudyZhao Chen
Division of Epidemiology and Biostatistics, Zuckerman College of Public Health, University of Arizona, PO Box 245203, 1540 E Drachman, Tucson, AZ 85724, USA
Arch Intern Med 165:552-8. 2005..We tested the hypothesis in the Women's Health Initiative Observational Study that postmenopausal survivors of breast cancer have a higher risk for fractures compared with women who have no cancer history...
Wheat bran fiber supplementation and bone loss among older peopleZhao Chen
Arizona Cancer Center, Tucson, USA
Nutrition 20:747-51. 2004..The purpose of this study was to investigate the effect of wheat bran fiber (WBF) supplementation on bone loss in older people...
Validity of self-report for fractures among a multiethnic cohort of postmenopausal women: results from the Women's Health Initiative observational study and clinical trialsZhao Chen
University of Arizona, Tucson, AZ, USA
Menopause 11:264-74. 2004..The purpose of this study is to examine the validity of, and factors associated with, the accuracy of self-report (participant-report and proxy-report) for fractures...
Low bone density and high percentage of body fat among men who were treated with androgen deprivation therapy for prostate carcinomaZhao Chen
Division of Epidemiology and Biostatistics, College of Public Health, University of Arizona, Tucson, Arizona 85716, USA
Cancer 95:2136-44. 2002..In the current case-control study, the authors examined the prevalence and magnitude of low bone density and obesity among men with prostate carcinoma who were treated with ADT...
The relationship between incidence of fractures and anemia in older multiethnic womenZhao Chen
Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona 85724, USA
J Am Geriatr Soc 58:2337-44. 2010....
Effect of hormone therapy on lean body mass, falls, and fractures: 6-year results from the Women's Health Initiative hormone trialsJennifer W Bea
Arizona Cancer Center, Tucson, AZ 85724 5024, USA
Menopause 18:44-52. 2011....
Rheumatoid arthritis is associated with less optimal hip structural geometryNicole C Wright
Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA
J Clin Densitom 15:39-48. 2012..Within the WHI-BMD, women with RA group had reduced BMD and structural geometry at baseline, and this reduction was seen at a fixed rate throughout the 9 yr of study...
Indigenous American ancestry is associated with arsenic methylation efficiency in an admixed population of northwest MexicoPaulina Gomez-Rubio
Department of Pharmacology and Toxicology, University of Arizona, Tucson, Arizona, USA
J Toxicol Environ Health A 75:36-49. 2012....
Arthritis increases the risk for fractures--results from the Women's Health InitiativeNicole C Wright
Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona, USA
J Rheumatol 38:1680-8. 2011..To examine the relationship between arthritis and fracture...
Stronger bone correlates with African admixture in African-American womenZhao Chen
Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ 85724, USA
J Bone Miner Res 26:2307-16. 2011..However, women with higher percent African admixture had larger reductions in bone strength than non-Hispanic white women during the follow-up...
Self-reported osteoarthritis, ethnicity, body mass index, and other associated risk factors in postmenopausal women-results from the Women's Health InitiativeNicole C Wright
Mel and Enid Zuckerman College of Public Health, Tuscon, Arizona, USA
J Am Geriatr Soc 56:1736-43. 2008..79, 3.91) women, indicating a significant interactive effect of BMI and ethnicity on odds of OA. In conclusion, OA is a highly prevalent condition in postmenopausal women, and there are differential effects according to ethnicity...
Lower trabecular volumetric BMD at metaphyseal regions of weight-bearing bones is associated with prior fracture in young girlsJoshua N Farr
Department of Physiological Sciences, University of Arizona, Tucson, AZ 85721 0093, USA
J Bone Miner Res 26:380-7. 2011..Lower trabecular vBMD at metaphyseal sites of long bones may be an early marker of skeletal fragility in girls...
Skeletal muscle fat content is inversely associated with bone strength in young girlsJoshua N Farr
Department of Physiological Sciences, University of Arizona, Tucson, AZ 85721 0093, USA
J Bone Miner Res 26:2217-25. 2011..03-0.05, p > .05), except the distal tibia (β = 0.09, p = .03). In conclusion, skeletal muscle fat content of the calf and thigh is inversely associated with weight-bearing bone strength in young girls...
Relationship of total body fat mass to weight-bearing bone volumetric density, geometry, and strength in young girlsJoshua N Farr
Department of Physiological Sciences, The University of Arizona, 1713 E University Blvd 93, Tucson, AZ 85721, USA
Bone 46:977-84. 2010..Nevertheless, girls with higher TBFM relative to body mass have markedly diminished vBMD, geometry, and bone strength at metaphyseal and diaphyseal sites of the femur and tibia...
Diet and health risk: risk patterns and disease-specific associationsJ R Marshall
Arizona Cancer Center, College of Medicine, University of Arizona, Tucson 85724, USA
Am J Clin Nutr 69:1351S-1356S. 1999..The most critical tasks for lessening bias in these epidemiologic descriptors are first, to lessen imprecision in measuring exposures, and second, to adjust association estimates for attenuation due to measurement imprecision...
Direct transport of cocaine from the nasal cavity to the brain following intranasal cocaine administration in ratsH S Chow
Department of Pharmacy Practice and Science, College of Pharmacy, The University of Arizona, Tucson, Arizona 85721, USA
J Pharm Sci 88:754-8. 1999..We conclude that nasally administered cocaine was transported directly from the nasal cavity to the brain but that only a very small fraction of the dose was transported via the direct pathway...
Performance evaluation of a multiplex assay for future use in biomarker discovery efforts to predict body compositionJennifer W Bea
Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA
Clin Chem Lab Med 49:817-24. 2011..We sought to determine the best blood fraction for multiplex evaluation of circulating biomarkers in post-menopausal women, and to explore body composition phenotype discrimination by biomarkers...
Association between body mass index and arsenic methylation efficiency in adult women from southwest U.S. and northwest MexicoPaulina Gomez-Rubio
Department of Pharmacology and Toxicology, University of Arizona, Tucson, AZ 85721 0207, USA
Toxicol Appl Pharmacol 252:176-82. 2011....
Pilot study of dietary influences on mammographic density in pre- and postmenopausal Hispanic and non-Hispanic white womenCynthia A Thomson
Department of Nutritional Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson 85721 0038, USA
Menopause 14:243-50. 2007....
Ethnicity and breast cancer: factors influencing differences in incidence and outcomeRowan T Chlebowski
Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, 1124 W Carson St, Building J 3, Torrance, CA 90502, USA
J Natl Cancer Inst 97:439-48. 2005..The influence of breast cancer risk factors on these differences has received little attention...
Bone mineral density of American Indian and Alaska Native women compared with non-Hispanic white women: results from the Women's Health Initiative StudyNina S Wampler
Noqsi Research, Pine, CO 80470, USA
Menopause 12:536-44. 2005..To compare bone mineral density (BMD) of American Indian/Alaska Native (AI/AN) women with that of non-Hispanic white women...
Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized trialJane A Cauley
Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA
JAMA 290:1729-38. 2003..In the Women's Health Initiative trial of estrogen-plus-progestin therapy, women assigned to active treatment had fewer fractures...
Ethnic and geographic differences in mammographic density and their association with breast cancer incidenceGertraud Maskarinec
Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
Breast Cancer Res Treat 104:47-56. 2007..This comparison of mammographic densities suggests that, on a group level, age-adjusted dense areas may reflect breast cancer incidence better than percent densities...
IGF-I and mammographic density in four geographic locations: a pooled analysisGertraud Maskarinec
Cancer Research Center, University of Hawaii, Honolulu, HI 96813, USA
Int J Cancer 121:1786-92. 2007..Based on this analysis, the influence of circulating levels of IGF-I, IGFBP-3, and prolactin on percent density appears to be very small...
A new total body potassium method to estimate total body skeletal muscle mass in childrenZiMian Wang
Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
J Nutr 137:1988-91. 2007..Because the adult TBK SM prediction model is not applicable for pediatric use, this study provides new empirical TBK SM prediction equations that should prove useful for studies on nutrition, growth, and development in children...
Statin use, clinical fracture, and bone density in postmenopausal women: results from the Women's Health Initiative Observational StudyAndrea Z LaCroix
Women's Health Initiative Clinical Coordinating Center, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, MP-1002, PO Box 19024, Seattle, Washington 98109-1024, USA
Ann Intern Med 139:97-104. 2003..CONCLUSION: Statin use did not improve fracture risk or bone density in the Women's Health Initiative Observational Study. The cumulative evidence does not warrant use of statins to prevent or treat osteoporosis...
Associations between mammographic density and body composition in Hispanic and non-Hispanic white women by menopause statusGraciela Caire-Juvera
Nutrition Department, Centro de Investigacion en Alimentacion y Desarrollo, Sonora, Mexico
Menopause 15:319-25. 2008..To evaluate the associations of body composition, including percentage of lean and fat mass, with the percentage of mammographic density and mammographic dense area among pre- and postmenopausal Hispanic and non-Hispanic white women...
Factors associated with 5-year risk of hip fracture in postmenopausal womenJohn Robbins
Department of Internal Medicine, University of California at Davis School of Medicine, Sacramento, CA 95817, USA
JAMA 298:2389-98. 2007..The 329,000 hip fractures that annually occur in the United States are associated with high morbidity, mortality, and cost. Identification of those at high risk is a step toward prevention...
[The current status of schistosomiasis epidemics in China]Xiao-Nong Zhou
National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025, China
Zhonghua Liu Xing Bing Xue Za Zhi 25:555-8. 2004..CONCLUSION: The tendency of increase was presented in focal areas along the Yangtze River, due to changes of environmental, ecological, societal and economic status, as well as on the forces of control...
Clinical risk factors for fractures in multi-ethnic women: the Women's Health InitiativeJane A Cauley
Department of Epidemiology, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, Pennsylvania, USA
J Bone Miner Res 22:1816-26. 2007..However, irrespective of their ethnicity, women with multiple risk factors have a high risk of fracture. Targeting these high-risk women for screening and intervention could reduce fractures...
Computerized analysis of tissue density effect on missed cancer detection in digital mammographyLihua Li
Department of Interdisciplinary Oncology, H Lee Moffitt Cancer Center and Research Institute, University of South Florida, 12902 Magnolia Dr, Tampa, FL 33612, USA
Comput Med Imaging Graph 30:291-7. 2006..In order to improve early detection of breast cancer, a special effort should be directed to the high dense breast cases in CAD system design...
Low-fat dietary pattern and risk of treated diabetes mellitus in postmenopausal women: the Women's Health Initiative randomized controlled dietary modification trialLesley F Tinker
Women s Health Initiative, Fred Hutchinson Cancer Research Center, PO Box 19024, Mail Stop M3 A410, Seattle, WA 98109, USA
Arch Intern Med 168:1500-11. 2008..This study was undertaken to assess the effects of a low-fat dietary pattern on incidence of treated diabetes among generally healthy postmenopausal women...
Metabolically active portion of fat-free mass: a cellular body composition level modeling analysisZiMian Wang
Obesity Research Center, 1090 Amsterdam Ave, 14th Floor, New York, NY 10025, USA
Am J Physiol Endocrinol Metab 292:E49-53. 2007..584 +/- 0.041 and 0.529 +/- 0.041 for adult men and women (P < 0.001), respectively. A multiple linear regression model showed that there are independent significant associations of sex, age, and fat mass with BCM/FFM...
Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicronsFrederik Van Dyck
Department of Human Genetics, University of Leuven, B 3000 Leuven, Belgium
Cell Metab 6:406-13. 2007..PlagL2 thus regulates important aspects of dietary lipid absorption, and the PlagL2(-/-) animal model has implications for the amelioration of obesity and the metabolic syndrome...
