Zhao Chen

Summary

Affiliation: University of Arizona
Country: USA

Publications

  1. ncbi request reprint Habitual tea consumption and risk of osteoporosis: a prospective study in the women's health initiative observational cohort
    Z Chen
    Arizona College of Public Health, University of Arizona, Tucson, AZ 85716, USA
    Am J Epidemiol 158:772-81. 2003
  2. pmc Hormone therapy improves femur geometry among ethnically diverse postmenopausal participants in the Women's Health Initiative hormone intervention trials
    Zhao Chen
    Division of Epidemiology and Biostatistics, University of Arizona, Tucson, Arizona 85724 5211, USA
    J Bone Miner Res 23:1935-45. 2008
  3. pmc Hip bone density predicts breast cancer risk independently of Gail score: results from the Women's Health Initiative
    Zhao Chen
    Division of Epidemiology and Biostatistics, University of Arizona College of Public Health, Tucson, Arizona 85724 5211, USA
    Cancer 113:907-15. 2008
  4. pmc Fracture risk increases after diagnosis of breast or other cancers in postmenopausal women: results from the Women's Health Initiative
    Z Chen
    Division of Epidemiology and Biostatistics, University of Arizona Mel and Enid Zuckerman College of Public Health, Tucson, AZ 85724 5211, USA
    Osteoporos Int 20:527-36. 2009
  5. ncbi request reprint Postmenopausal hormone therapy and body composition--a substudy of the estrogen plus progestin trial of the Women's Health Initiative
    Zhao Chen
    Division of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ 85724, USA
    Am J Clin Nutr 82:651-6. 2005
  6. ncbi request reprint Osteoporosis and rate of bone loss among postmenopausal survivors of breast cancer
    Zhao Chen
    Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona 85724, USA
    Cancer 104:1520-30. 2005
  7. ncbi request reprint Dual-energy X-ray absorptiometry is a valid tool for assessing skeletal muscle mass in older women
    Zhao Chen
    College of Public Health, University of Arizona, Tucson, AZ 85724, USA
    J Nutr 137:2775-80. 2007
  8. ncbi request reprint Fracture risk among breast cancer survivors: results from the Women's Health Initiative Observational Study
    Zhao Chen
    Division of Epidemiology and Biostatistics, Zuckerman College of Public Health, University of Arizona, PO Box 245203, 1540 E Drachman, Tucson, AZ 85724, USA
    Arch Intern Med 165:552-8. 2005
  9. ncbi request reprint Wheat bran fiber supplementation and bone loss among older people
    Zhao Chen
    Arizona Cancer Center, Tucson, USA
    Nutrition 20:747-51. 2004
  10. ncbi request reprint Validity of self-report for fractures among a multiethnic cohort of postmenopausal women: results from the Women's Health Initiative observational study and clinical trials
    Zhao Chen
    University of Arizona, Tucson, AZ, USA
    Menopause 11:264-74. 2004

Detail Information

Publications42

  1. ncbi request reprint Habitual tea consumption and risk of osteoporosis: a prospective study in the women's health initiative observational cohort
    Z Chen
    Arizona College of Public Health, University of Arizona, Tucson, AZ 85716, USA
    Am J Epidemiol 158:772-81. 2003
    ..In conclusion, the results from this study indicate that the effect of habitual tea drinking on bone density is small and does not significantly alter the risk of fractures among the US postmenopausal population...
  2. pmc Hormone therapy improves femur geometry among ethnically diverse postmenopausal participants in the Women's Health Initiative hormone intervention trials
    Zhao Chen
    Division of Epidemiology and Biostatistics, University of Arizona, Tucson, Arizona 85724 5211, USA
    J Bone Miner Res 23:1935-45. 2008
    ..3-3.6% for section modulus and -5.3% to - 4.3% for buckling ratio. Hormone interventions led to favorable changes in femur geometry, which may help explain the reduced fracture risk observed in hormone interventions...
  3. pmc Hip bone density predicts breast cancer risk independently of Gail score: results from the Women's Health Initiative
    Zhao Chen
    Division of Epidemiology and Biostatistics, University of Arizona College of Public Health, Tucson, Arizona 85724 5211, USA
    Cancer 113:907-15. 2008
    ..The objective of the current study was to investigate whether hip BMD predicts postmenopausal breast cancer risk independently of the Gail score...
  4. pmc Fracture risk increases after diagnosis of breast or other cancers in postmenopausal women: results from the Women's Health Initiative
    Z Chen
    Division of Epidemiology and Biostatistics, University of Arizona Mel and Enid Zuckerman College of Public Health, Tucson, AZ 85724 5211, USA
    Osteoporos Int 20:527-36. 2009
    ..Risk for falls and fractures increases after breast cancer or other cancer diagnosis in postmenopausal women. Factors other than falls may be the major causes for the increased fracture risk...
  5. ncbi request reprint Postmenopausal hormone therapy and body composition--a substudy of the estrogen plus progestin trial of the Women's Health Initiative
    Zhao Chen
    Division of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ 85724, USA
    Am J Clin Nutr 82:651-6. 2005
    ..It has been suggested that hormone therapy may help counter undesirable changes in body composition in older women...
  6. ncbi request reprint Osteoporosis and rate of bone loss among postmenopausal survivors of breast cancer
    Zhao Chen
    Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona 85724, USA
    Cancer 104:1520-30. 2005
    ..Breast cancer diagnosis and treatment may put women at higher risk for osteoporosis in later life...
  7. ncbi request reprint Dual-energy X-ray absorptiometry is a valid tool for assessing skeletal muscle mass in older women
    Zhao Chen
    College of Public Health, University of Arizona, Tucson, AZ 85724, USA
    J Nutr 137:2775-80. 2007
    ..We conclude that DXA is a reliable method for cross-sectional assessments of SMM in older women...
  8. ncbi request reprint Fracture risk among breast cancer survivors: results from the Women's Health Initiative Observational Study
    Zhao Chen
    Division of Epidemiology and Biostatistics, Zuckerman College of Public Health, University of Arizona, PO Box 245203, 1540 E Drachman, Tucson, AZ 85724, USA
    Arch Intern Med 165:552-8. 2005
    ..We tested the hypothesis in the Women's Health Initiative Observational Study that postmenopausal survivors of breast cancer have a higher risk for fractures compared with women who have no cancer history...
  9. ncbi request reprint Wheat bran fiber supplementation and bone loss among older people
    Zhao Chen
    Arizona Cancer Center, Tucson, USA
    Nutrition 20:747-51. 2004
    ..The purpose of this study was to investigate the effect of wheat bran fiber (WBF) supplementation on bone loss in older people...
  10. ncbi request reprint Validity of self-report for fractures among a multiethnic cohort of postmenopausal women: results from the Women's Health Initiative observational study and clinical trials
    Zhao Chen
    University of Arizona, Tucson, AZ, USA
    Menopause 11:264-74. 2004
    ..The purpose of this study is to examine the validity of, and factors associated with, the accuracy of self-report (participant-report and proxy-report) for fractures...
  11. ncbi request reprint Low bone density and high percentage of body fat among men who were treated with androgen deprivation therapy for prostate carcinoma
    Zhao Chen
    Division of Epidemiology and Biostatistics, College of Public Health, University of Arizona, Tucson, Arizona 85716, USA
    Cancer 95:2136-44. 2002
    ..In the current case-control study, the authors examined the prevalence and magnitude of low bone density and obesity among men with prostate carcinoma who were treated with ADT...
  12. pmc The relationship between incidence of fractures and anemia in older multiethnic women
    Zhao Chen
    Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona 85724, USA
    J Am Geriatr Soc 58:2337-44. 2010
    ....
  13. pmc Effect of hormone therapy on lean body mass, falls, and fractures: 6-year results from the Women's Health Initiative hormone trials
    Jennifer W Bea
    Arizona Cancer Center, Tucson, AZ 85724 5024, USA
    Menopause 18:44-52. 2011
    ....
  14. pmc Rheumatoid arthritis is associated with less optimal hip structural geometry
    Nicole C Wright
    Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA
    J Clin Densitom 15:39-48. 2012
    ..Within the WHI-BMD, women with RA group had reduced BMD and structural geometry at baseline, and this reduction was seen at a fixed rate throughout the 9 yr of study...
  15. pmc Indigenous American ancestry is associated with arsenic methylation efficiency in an admixed population of northwest Mexico
    Paulina Gomez-Rubio
    Department of Pharmacology and Toxicology, University of Arizona, Tucson, Arizona, USA
    J Toxicol Environ Health A 75:36-49. 2012
    ....
  16. pmc Arthritis increases the risk for fractures--results from the Women's Health Initiative
    Nicole C Wright
    Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona, USA
    J Rheumatol 38:1680-8. 2011
    ..To examine the relationship between arthritis and fracture...
  17. doi request reprint Stronger bone correlates with African admixture in African-American women
    Zhao Chen
    Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ 85724, USA
    J Bone Miner Res 26:2307-16. 2011
    ..However, women with higher percent African admixture had larger reductions in bone strength than non-Hispanic white women during the follow-up...
  18. pmc Lower trabecular volumetric BMD at metaphyseal regions of weight-bearing bones is associated with prior fracture in young girls
    Joshua N Farr
    Department of Physiological Sciences, University of Arizona, Tucson, AZ 85721 0093, USA
    J Bone Miner Res 26:380-7. 2011
    ..Lower trabecular vBMD at metaphyseal sites of long bones may be an early marker of skeletal fragility in girls...
  19. pmc Self-reported osteoarthritis, ethnicity, body mass index, and other associated risk factors in postmenopausal women-results from the Women's Health Initiative
    Nicole C Wright
    Mel and Enid Zuckerman College of Public Health, Tuscon, Arizona, USA
    J Am Geriatr Soc 56:1736-43. 2008
    ..79, 3.91) women, indicating a significant interactive effect of BMI and ethnicity on odds of OA. In conclusion, OA is a highly prevalent condition in postmenopausal women, and there are differential effects according to ethnicity...
  20. doi request reprint Skeletal muscle fat content is inversely associated with bone strength in young girls
    Joshua N Farr
    Department of Physiological Sciences, University of Arizona, Tucson, AZ 85721 0093, USA
    J Bone Miner Res 26:2217-25. 2011
    ..03-0.05, p > .05), except the distal tibia (β = 0.09, p = .03). In conclusion, skeletal muscle fat content of the calf and thigh is inversely associated with weight-bearing bone strength in young girls...
  21. pmc Relationship of total body fat mass to weight-bearing bone volumetric density, geometry, and strength in young girls
    Joshua N Farr
    Department of Physiological Sciences, The University of Arizona, 1713 E University Blvd 93, Tucson, AZ 85721, USA
    Bone 46:977-84. 2010
    ..Nevertheless, girls with higher TBFM relative to body mass have markedly diminished vBMD, geometry, and bone strength at metaphyseal and diaphyseal sites of the femur and tibia...
  22. ncbi request reprint Diet and health risk: risk patterns and disease-specific associations
    J R Marshall
    Arizona Cancer Center, College of Medicine, University of Arizona, Tucson 85724, USA
    Am J Clin Nutr 69:1351S-1356S. 1999
    ..The most critical tasks for lessening bias in these epidemiologic descriptors are first, to lessen imprecision in measuring exposures, and second, to adjust association estimates for attenuation due to measurement imprecision...
  23. ncbi request reprint Direct transport of cocaine from the nasal cavity to the brain following intranasal cocaine administration in rats
    H S Chow
    Department of Pharmacy Practice and Science, College of Pharmacy, The University of Arizona, Tucson, Arizona 85721, USA
    J Pharm Sci 88:754-8. 1999
    ..We conclude that nasally administered cocaine was transported directly from the nasal cavity to the brain but that only a very small fraction of the dose was transported via the direct pathway...
  24. pmc Performance evaluation of a multiplex assay for future use in biomarker discovery efforts to predict body composition
    Jennifer W Bea
    Arizona Cancer Center, University of Arizona, Tucson, AZ 85724, USA
    Clin Chem Lab Med 49:817-24. 2011
    ..We sought to determine the best blood fraction for multiplex evaluation of circulating biomarkers in post-menopausal women, and to explore body composition phenotype discrimination by biomarkers...
  25. pmc Association between body mass index and arsenic methylation efficiency in adult women from southwest U.S. and northwest Mexico
    Paulina Gomez-Rubio
    Department of Pharmacology and Toxicology, University of Arizona, Tucson, AZ 85721 0207, USA
    Toxicol Appl Pharmacol 252:176-82. 2011
    ....
  26. ncbi request reprint Pilot study of dietary influences on mammographic density in pre- and postmenopausal Hispanic and non-Hispanic white women
    Cynthia A Thomson
    Department of Nutritional Sciences, College of Agriculture and Life Sciences, University of Arizona, Tucson 85721 0038, USA
    Menopause 14:243-50. 2007
    ....
  27. pmc Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network
    Zhao Chen
    Division of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ 85724, USA
    Hum Mol Genet 22:2529-38. 2013
    ....
  28. ncbi request reprint Statin use, clinical fracture, and bone density in postmenopausal women: results from the Women's Health Initiative Observational Study
    Andrea Z LaCroix
    Women s Health Initiative Clinical Coordinating Center, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, MP 1002, PO Box 19024, Seattle, Washington 98109 1024, USA
    Ann Intern Med 139:97-104. 2003
    ..While early epidemiologic studies showed lower risk for hip fracture among statin users than nonusers, subsequent studies have produced mixed results...
  29. ncbi request reprint Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women's Health Initiative randomized trial
    Jane A Cauley
    Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA
    JAMA 290:1729-38. 2003
    ..In the Women's Health Initiative trial of estrogen-plus-progestin therapy, women assigned to active treatment had fewer fractures...
  30. ncbi request reprint Ethnicity and breast cancer: factors influencing differences in incidence and outcome
    Rowan T Chlebowski
    Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, 1124 W Carson St, Building J 3, Torrance, CA 90502, USA
    J Natl Cancer Inst 97:439-48. 2005
    ..The influence of breast cancer risk factors on these differences has received little attention...
  31. ncbi request reprint Bone mineral density of American Indian and Alaska Native women compared with non-Hispanic white women: results from the Women's Health Initiative Study
    Nina S Wampler
    Noqsi Research, Pine, CO 80470, USA
    Menopause 12:536-44. 2005
    ..To compare bone mineral density (BMD) of American Indian/Alaska Native (AI/AN) women with that of non-Hispanic white women...
  32. ncbi request reprint Factors associated with 5-year risk of hip fracture in postmenopausal women
    John Robbins
    Department of Internal Medicine, University of California at Davis School of Medicine, Sacramento, CA 95817, USA
    JAMA 298:2389-98. 2007
    ..The 329,000 hip fractures that annually occur in the United States are associated with high morbidity, mortality, and cost. Identification of those at high risk is a step toward prevention...
  33. ncbi request reprint Ethnic and geographic differences in mammographic density and their association with breast cancer incidence
    Gertraud Maskarinec
    Cancer Research Center of Hawaii, 1236 Lauhala Street, Honolulu, HI 96813, USA
    Breast Cancer Res Treat 104:47-56. 2007
    ..This comparison of mammographic densities suggests that, on a group level, age-adjusted dense areas may reflect breast cancer incidence better than percent densities...
  34. ncbi request reprint IGF-I and mammographic density in four geographic locations: a pooled analysis
    Gertraud Maskarinec
    Cancer Research Center, University of Hawaii, Honolulu, HI 96813, USA
    Int J Cancer 121:1786-92. 2007
    ..Based on this analysis, the influence of circulating levels of IGF-I, IGFBP-3, and prolactin on percent density appears to be very small...
  35. ncbi request reprint Associations between mammographic density and body composition in Hispanic and non-Hispanic white women by menopause status
    Graciela Caire-Juvera
    Nutrition Department, Centro de Investigacion en Alimentacion y Desarrollo, Sonora, Mexico
    Menopause 15:319-25. 2008
    ..To evaluate the associations of body composition, including percentage of lean and fat mass, with the percentage of mammographic density and mammographic dense area among pre- and postmenopausal Hispanic and non-Hispanic white women...
  36. pmc A new total body potassium method to estimate total body skeletal muscle mass in children
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10025, USA
    J Nutr 137:1988-91. 2007
    ..Because the adult TBK SM prediction model is not applicable for pediatric use, this study provides new empirical TBK SM prediction equations that should prove useful for studies on nutrition, growth, and development in children...
  37. ncbi request reprint Computerized analysis of tissue density effect on missed cancer detection in digital mammography
    Lihua Li
    Department of Interdisciplinary Oncology, H Lee Moffitt Cancer Center and Research Institute, University of South Florida, 12902 Magnolia Dr, Tampa, FL 33612, USA
    Comput Med Imaging Graph 30:291-7. 2006
    ..In order to improve early detection of breast cancer, a special effort should be directed to the high dense breast cases in CAD system design...
  38. ncbi request reprint [The current status of schistosomiasis epidemics in China]
    Xiao Nong Zhou
    National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025, China
    Zhonghua Liu Xing Bing Xue Za Zhi 25:555-8. 2004
    ..To analyze the change of tendency on schistosomiasis epidemics in China in the last 5 years...
  39. ncbi request reprint Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons
    Frederik Van Dyck
    Department of Human Genetics, University of Leuven, B 3000 Leuven, Belgium
    Cell Metab 6:406-13. 2007
    ..PlagL2 thus regulates important aspects of dietary lipid absorption, and the PlagL2(-/-) animal model has implications for the amelioration of obesity and the metabolic syndrome...
  40. doi request reprint Low-fat dietary pattern and risk of treated diabetes mellitus in postmenopausal women: the Women's Health Initiative randomized controlled dietary modification trial
    Lesley F Tinker
    Women s Health Initiative, Fred Hutchinson Cancer Research Center, PO Box 19024, Mail Stop M3 A410, Seattle, WA 98109, USA
    Arch Intern Med 168:1500-11. 2008
    ..This study was undertaken to assess the effects of a low-fat dietary pattern on incidence of treated diabetes among generally healthy postmenopausal women...
  41. pmc Metabolically active portion of fat-free mass: a cellular body composition level modeling analysis
    ZiMian Wang
    Obesity Research Center, 1090 Amsterdam Ave, 14th Floor, New York, NY 10025, USA
    Am J Physiol Endocrinol Metab 292:E49-53. 2007
    ..584 +/- 0.041 and 0.529 +/- 0.041 for adult men and women (P < 0.001), respectively. A multiple linear regression model showed that there are independent significant associations of sex, age, and fat mass with BCM/FFM...
  42. ncbi request reprint Clinical risk factors for fractures in multi-ethnic women: the Women's Health Initiative
    Jane A Cauley
    Department of Epidemiology, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, Pennsylvania, USA
    J Bone Miner Res 22:1816-26. 2007
    ..However, irrespective of their ethnicity, women with multiple risk factors have a high risk of fracture. Targeting these high-risk women for screening and intervention could reduce fractures...