Research Topics
Species | Yunn Yi ChenSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Genetic and phenotypic characteristics of pleomorphic lobular carcinoma in situ of the breastYunn Yi Chen
Department of Pathology, University of California San Francisco, California 94143, USA
Am J Surg Pathol 33:1683-94. 2009..However, clinical follow-up studies will be required to define the natural history and most appropriate management of these lesions...- Pathologic and biologic response to preoperative endocrine therapy in patients with ER-positive ductal carcinoma in situYunn Yi Chen
Department of Surgery, University of California San Francisco, San Francisco, USA
BMC Cancer 9:285. 2009.... 
Protein acetylation and histone deacetylase expression associated with malignant breast cancer progressionJunko Suzuki
Department of Laboratory Medicine, University of California, San Francisco, CA, USA
Clin Cancer Res 15:3163-71. 2009..However, HDAC expression and protein acetylation have not been studied in the context of breast cancer progression...- D2-40 expression by breast myoepithelium: potential pitfalls in distinguishing intralymphatic carcinoma from in situ carcinomaJoseph T Rabban
Department of Pathology, University of California San Francisco, San Francisco, CA 94143, USA
Hum Pathol 39:175-83. 2008..We recommend that myoepithelial markers be used in conjunction with D2-40 to distinguish solid intralymphatic tumor emboli from solid pattern in situ carcinoma... 
Clinical application of array-based comparative genomic hybridization to define the relationship between multiple synchronous tumorsChrystal V Wa
Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA
Mod Pathol 18:591-7. 2005..We conclude that genetic analysis by array-based CGH can clearly elucidate the relationships between multiple tumors and may potentially serve as an important clinical tool...- Genomic alterations and phenotype of large compared to small high-grade ductal carcinoma in situE Shelley Hwang
Department of Surgery, University of California San Francisco, San Francisco, CA 94143 1710, USA
Hum Pathol 42:1467-75. 2011..Interestingly, larger tumors showed some molecular features associated with better prognosis. A more thorough evaluation of these differences could help identify the likelihood of recurrence or progression for in situ lesions... - Identification of a robust gene signature that predicts breast cancer outcome in independent data setsJames E Korkola
Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA
BMC Cancer 7:61. 2007..Breast cancer is a heterogeneous disease, presenting with a wide range of histologic, clinical, and genetic features. Microarray technology has shown promise in predicting outcome in these patients... - Increased beta1 integrin is associated with decreased survival in invasive breast cancerEvelyn S Yao
Department of Radiation Oncology, Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California 94143 1708, and Lawrence Berkeley National Laboratory, Berkeley, California, USA
Cancer Res 67:659-64. 2007.... - Magnetic resonance imaging captures the biology of ductal carcinoma in situLaura J Esserman
Department of Surgery, University of California, San Francisco, USA
J Clin Oncol 24:4603-10. 2006..We investigated whether MRI features of DCIS reflect differences in biology and pathology... - CD36 repression activates a multicellular stromal program shared by high mammographic density and tumor tissuesRosa Anna DeFilippis
Department of Pathology, Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94143, USA
Cancer Discov 2:826-39. 2012..Levels of CD36 and extent of mammographic density are both modifiable factors that provide potential for intervention... - Fibroepithelial lesions with cellular stroma on breast core needle biopsy: are there predictors of outcome on surgical excision?Timothy W Jacobs
Department of Pathology, Virginia Mason Medical Center, Seattle, WA 98101, USA
Am J Clin Pathol 124:342-54. 2005..Assessment of stromal cellularity, mitoses, and proliferation indices might help determine the probability of phyllodes tumor occurring and guide management of these cases... - Array-based comparative genomic hybridization of ductal carcinoma in situ and synchronous invasive lobular cancerSarah J Nyante
Department of Surgery, University of California San Francisco, 94115, USA
Hum Pathol 35:759-63. 2004..The following case illustrates how array CGH may be used to better understand whether synchronous neoplasms share a common origin... - Pure and predominantly pure intralymphatic breast carcinoma after neoadjuvant chemotherapy: an unusual and adverse pattern of residual diseaseJoseph T Rabban
Department of Pathology, University of California San Francisco, San Francisco, CA 94143, USA
Am J Surg Pathol 33:256-63. 2009..D2-40 immunostaining is useful in this setting. Current staging criteria should be clarified to define whether extensive intralymphatic tumor should be incorporated in tumor stage assignment... - Abrogated response to cellular stress identifies DCIS associated with subsequent tumor events and defines basal-like breast tumorsMona L Gauthier
Department of Pathology, University of California, San Francisco, CA 94143, USA
Cancer Cell 12:479-91. 2007..Assessment of these biomarkers in DCIS begins to allow prediction of tumor formation years before it actually occurs... - Immunophenotypic overlap between adenoid cystic carcinoma and collagenous spherulosis of the breast: potential diagnostic pitfalls using myoepithelial markersJoseph T Rabban
Department of Pathology, University of California, San Francisco, CA 94143, USA
Mod Pathol 19:1351-7. 2006..Reliance on p63 or smooth muscle actin alone poses a potential diagnostic pitfall in evaluating cribriform breast lesions... - Topographic enhancement mapping of the cancer-associated breast stroma using breast MRINima Nabavizadeh
Department of Radiation Oncology, University of California, San Francisco Comprehensive Cancer Center, 1600 Divisadero Street H1031, San Francisco, CA 94143 1708, USA
Integr Biol (Camb) 3:490-6. 2011..Identification of a cancer-associated stroma may be further developed to help guide local therapy to reduce recurrence and morbidity in breast cancer patients... - Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: results from the I-SPY 1 TRIAL--CALGB 150007/150012, ACRIN 6657Laura J Esserman
Breast Care Center, University of California at San Francisco, 1600 Divisadero St, 2nd Floor, Box 1710, San Francisco, CA 94115, USA
J Clin Oncol 30:3242-9. 2012.... - Glycogenic hepatopathy: an underrecognized hepatic complication of diabetes mellitusMichael Torbenson
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA
Am J Surg Pathol 30:508-13. 2006..We conclude that glycogenic hepatopathy can cause hepatomegaly and significant transaminase elevations in individuals with type I diabetes mellitus. The pathology is distinct from steatohepatitis...