Research Topics
Genomes and Genes | Yin ChenSummaryAffiliation: University of California Country: USA Publications
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Publications
Rhinovirus induces airway epithelial gene expression through double-stranded RNA and IFN-dependent pathwaysYin Chen
Center for Comparative Respiratory Biology and Medicine, Genomic and Biomedical Sciences Facility, Suite 6510, University of California at Davis, One Shields Ave, Davis, CA 95616, USA
Am J Respir Cell Mol Biol 34:192-203. 2006....
Up-regulation of CC chemokine ligand 20 expression in human airway epithelium by IL-17 through a JAK-independent but MEK/NF-kappaB-dependent signaling pathwayCheng-Yuan Kao
Center for Comparative Respiratory Biology and Medicine, University of California, Davis, CA 95616, USA
J Immunol 175:6676-85. 2005..These results suggest that IL-17 can coordinately up-regulate both hBD-2 and CCL20 expressions in airways through differentially JAK-dependent and -independent activations of NF-kappaB-based transcriptional mechanisms, respectively...- Differential regulation of MUC5AC/Muc5ac and hCLCA-1/mGob-5 expression in airway epitheliumPhilip Thai
Center for Comparative Respiratory Biology and Medicine, Surge 1, Room 1121, University of California at Davis, One Shields Avenue, Davis, CA 95616, USA
Am J Respir Cell Mol Biol 33:523-30. 2005..Thus, these results suggest that the two biomakers of the metaplastic airway mucous cell type are differentially regulated by JAK/STAT6-dependent and -independent pathways... - Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epitheliumRichart W Harper
Department of Internal Medicine, Division of Pulmonary Critical Care Medicine, School of Medicine, University of California, Davis, CA 95616, USA
FEBS Lett 579:4911-7. 2005.... - NF-κB mediates IL-1β- and IL-17A-induced MUC5B expression in airway epithelial cellsTomoyuki Fujisawa
Center for Comparative Respiratory Biology and Medicine, University of California at Davis, 95616, USA
Am J Respir Cell Mol Biol 45:246-52. 2011..This is the first demonstration of the participation of NF-κB and its specific binding site in cytokine-mediated airway MUC5B expression... - Genome-wide search and identification of a novel gel-forming mucin MUC19/Muc19 in glandular tissuesYin Chen
Center for Comparative Respiratory Biology and Medicine, University of California at Davis, Davis, CA 95616, USA
Am J Respir Cell Mol Biol 30:155-65. 2004..Based on the chronological convention, we have given the name MUC19 to the human ortholog and Muc19 to the mouse... - IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathwaysCheng-Yuan Kao
Center for Comparative Respiratory Biology and Medicine, University of California, Davis, CA 95616, USA
J Immunol 173:3482-91. 2004.... - Identification of a novel MAGE D2 antisense RNA transcript in human tissuesRichart Harper
Center for Comparative Respiratory Biology and Medicine, University of California, Davis, CA 95616, United States
Biochem Biophys Res Commun 324:199-204. 2004..Identification of this transcript potentially has important implications for future studies examining MAGE D2 expression patterns in cancer and normal tissues... - Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loopYin Chen
Center for Comparative Respiratory Biology and Medicine, University of California, Davis, California 95616, USA
J Biol Chem 278:17036-43. 2003..Finally, evidence is presented to show that both IL-6 and IL-17 mediate MUC5B expression through the ERK signaling pathway... - PMA stimulates MUC5B gene expression through an Sp1-based mechanism in airway epithelial cellsDaphne Y C Wu
Center for Comparative Respiratory Biology and Medicine, University of California at Davis, Davis, California 95616, USA
Am J Respir Cell Mol Biol 37:589-97. 2007..These results suggested an Sp1-based transcriptional mechanism with Sp1-1 as the regulator of basal MUC5B promoter activity and Sp1-2 as the regulator of PMA-induced MUC5B gene expression in the human airway epithelial cells... - Application of high-density DNA microarray to study smoke- and hydrogen peroxide-induced injury and repair in human bronchial epithelial cellsKen Yoneda
Department of Internal Medicine, University of California at Davis, Davis, California 95616, USA
J Am Soc Nephrol 14:S284-9. 2003..These results demonstrated a complex gene expression array by bronchial epithelial cells in response to a single insult of oxidants that are relevant to environmental pollutants... - ORFeome-based search of airway epithelial cell-specific novel human [beta]-defensin genesCheng Yuan Kao
Center for Comparative Respiratory Biology and Medicine, University of California at Davis, Davis, CA 95616, USA
Am J Respir Cell Mol Biol 29:71-80. 2003..These results support the utility of ORFeome-based HMM search in gene discovery for members of a specific gene family. The novel DEFB genes identified in this study may significantly contribute to overall antimicrobial host defenses... - Identification of Nrf2-dependent airway epithelial adaptive response to proinflammatory oxidant-hypochlorous acid challenge by transcription profilingLingxiang Zhu
Division of Translational Biology, The Hamner Institutes for Health Sciences, 6 Davis Dr, Research Triangle Park, NC 27709, USA
Am J Physiol Lung Cell Mol Physiol 294:L469-77. 2008..By both methods, we conclude that Nrf2 directly protects airway epithelial cells from HOCl-induced toxicity... - Molecular ecology techniques for the study of aerobic methanotrophsIan R McDonald
Department of Biological Sciences, University of Waikato, Private Bag 3105, Hamilton 3240, New Zealand
Appl Environ Microbiol 74:1305-15. 2008 - Diversity of the active methanotrophic community in acidic peatlands as assessed by mRNA and SIP-PLFA analysesYin Chen
Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
Environ Microbiol 10:446-59. 2008..The presence of (13)C-labelled 18:1 omega 9, which was not a major PLFA of any extant methanotrophs, indicated the presence of novel methanotrophs in this peatland... - Identity of active methanotrophs in landfill cover soil as revealed by DNA-stable isotope probingAurélie Cébron
Department of Biological Sciences, University of Warwick, Coventry, UK
FEMS Microbiol Ecol 62:12-23. 2007..Environmental conditions in the slightly acidic peat soil from Roscommon landfill cover allow establishment of both Type I and Type II methanotrophs... - Pathogenic and molecular characterization of the H5N1 avian influenza virus isolated from the first human case in Zhejiang province, ChinaJuying Yan
Institute of Virology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310009, China
Diagn Microbiol Infect Dis 58:399-405. 2007..The sequenced genes were all avian origin. Phylogenetic analyses between the A/Zhejiang/16/06 and other H5N1 influenza viruses were also included... - Paeoniflorin induced immune tolerance of mesenteric lymph node lymphocytes via enhancing beta 2-adrenergic receptor desensitization in rats with adjuvant arthritisHong Wu
Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Antiinflammatory immunopharmacology in Anhui Province, Key Laboratory of Research and Development of Chinese Medicine in Anhui Province, Hefei 230032, Anhui Province, China
Int Immunopharmacol 7:662-73. 2007..The mechanisms of Pae on beta 2-AR desensitization and beta 2-AR-AC-cAMP transmembrane signal transduction of MLN lymphocytes play crucial roles in pathogenesis of this disease... - Overexpression of celB gene coding for beta-glucosidase from Pyrococcus furiosus using a baculovirus expression vector system in silkworm, Bombyx moriXu Ai Lin
Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, 100081, China
Z Naturforsch C 61:595-600. 2006..4 U per silkworm larva, and the specific activity of the one-step purified crude enzyme was 885 U per mg. It was demonstrated to be an attractive approach for mass production of thermostable beta-glucosidase using this system... - Expression of ssDNA in mammalian cellsYin Chen
CytoGenix, Houston, TX, USA
Biotechniques 34:167-71. 2003..Our study further demonstrates the feasibility of using this novel ssDNA expression technology to produce intracellularly any sequence of interest, including antisense oligonucleotides and DNA enzyme molecules...