Research Topics
Species | Lee May ChenSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Perioperative outcomes comparing patient controlled epidural versus intravenous analgesia in gynecologic oncology surgeryLee May Chen
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA, USA
Gynecol Oncol 115:357-61. 2009..Our aim was to compare perioperative patient controlled epidural analgesia (PCEA) versus patient controlled intravenous analgesia (PCA) after gynecologic oncology laparotomy...
Single-agent pulse dactinomycin has only modest activity for methotrexate-resistant gestational trophoblastic neoplasiaLee May Chen
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco Medical Center, San Francisco, CA 94115 USA
Gynecol Oncol 94:204-7. 2004..To determine the effectiveness of single-agent pulse dactinomycin for methotrexate-resistant low-risk gestational trophoblastic neoplasia (GTN)...- Discordance between beliefs and recommendations of gynecologic oncologists in ovarian cancer managementL Chen
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
Int J Gynecol Cancer 14:1055-62. 2004..The purpose of this study was to determine how physician experts make decisions for clinical scenarios in ovarian cancer and describe a profile of factors reported to influence treatment decisions... - Gynecologic cancer prevention in Lynch syndrome/hereditary nonpolyposis colorectal cancer familiesLee May Chen
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, California, USA
Obstet Gynecol 110:18-25. 2007..This study models a comparison of management strategies for women who carry a Lynch/HNPCC mutation... - Influence of gynecologic oncologists on the survival of patients with endometrial cancerJohn K Chan
University of California, San Francisco UCSF School of Medicine, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143 1702, USA
J Clin Oncol 29:832-8. 2011..Therefore, we propose to determine the influence of gynecologic oncologists on the treatment and survival of patients with endometrial cancer... - Risk-reducing salpingo-oophorectomy (RRSO) in BRCA mutation carriers: experience with a consecutive series of 111 patients using a standardized surgical-pathological protocolC Bethan Powell
Cancer Risk Program, Department of Pathology, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94115, USA
Int J Gynecol Cancer 21:846-51. 2011..We report outcomes in 111 consecutive BRCA-positive women who had RRSO using a rigorous surgical-pathological protocol from 1996 to 2008... - Factors associated with publication of plenary presentations at the Society of Gynecologic Oncologists annual meetingJoshua G Cohen
Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, 1600 Divisadero Street, San Francisco, CA 94143 1702, USA
Gynecol Oncol 128:128-31. 2013..To determine the rate and factors associated with publication of plenary abstract presentations from the Society of Gynecologic Oncologists annual meeting... - Characteristics of success in mentoring and research productivity - a case-control study of academic centersJoshua G Cohen
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA 94143 1702, USA
Gynecol Oncol 125:8-13. 2012..Thus, we performed a case-control study to identify characteristics of successful mentoring programs... - Rules of tumor cell development and their application to biomarkers for ovarian cancerMonica R McLemore
Department of Physiological Nursing, University of California, San Francisco, USA
Oncol Nurs Forum 35:403-9. 2008..To apply the Hanahan and Weinberg conceptual framework for tumor development to the specific biomarkers observed or expressed in ovarian cancer... - Surveillance of survivors: follow-up after risk-reducing salpingo-oophorectomy in BRCA 1/2 mutation carriersJocelyn S Chapman
UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143, USA
Gynecol Oncol 122:339-43. 2011..To characterize the post-operative care of BRCA1 and BRCA2 mutation carriers who undergo risk-reducing salpingo-oophorectomy (RRSO)... - Correlation of macroscopic and microscopic pathology in risk reducing salpingo-oophorectomy: implications for intraoperative specimen evaluationJoseph T Rabban
Department of Pathology, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94313, USA
Gynecol Oncol 121:466-71. 2011..The aim of this study was to correlate the macroscopic and microscopic pathologic findings in RRSO... 
Function of UDP-glucuronosyltransferase 2B17 (UGT2B17) is involved in endometrial cancerHiroshi Hirata
Department of Urology, Veterans Affairs Medical Center and University of California at San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
Carcinogenesis 31:1620-6. 2010..This is the first report to show that UGT2B17 and Mcl-1 expression are upregulated in EC tissues and that UGT2B17 depletion induces inhibition of cell growth and apoptosis in EC cells through Mcl-1 downregulation...- Multistep level sections to detect occult fallopian tube carcinoma in risk-reducing salpingo-oophorectomies from women with BRCA mutations: implications for defining an optimal specimen dissection protocolJoseph T Rabban
Department of Pathology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA
Am J Surg Pathol 33:1878-85. 2009..Guidelines for evaluation of RRSO specimens should emphasize the use of an optimal dissection protocol and the importance of thin tissue slice intervals... - Synchronous ovarian granulosa cell tumor and uterine serous carcinoma: a rare association of a high-risk endometrial cancer with anestrogenic ovarian tumorJoseph T Rabban
Department of Pathology, University of California, San Francisco, CA 94143, USA
Gynecol Oncol 103:1164-8. 2006..The endometrial carcinoma is thought to occur under the influence of the estrogen receptor pathway and is typically a low-grade, low-stage endometrioid adenocarcinoma... - High-dose rate brachytherapy using inverse planning simulated annealing for locoregionally advanced cervical cancer: a clinical report with 2-year follow-upDaniel H Kim
Department of Radiation Oncology, University of California, San Francisco, CA, USA
Int J Radiat Oncol Biol Phys 75:1329-34. 2009..We present clinical outcomes of image-guided brachytherapy using inverse planning simulated annealing (IPSA) planned high-dose rate (HDR) brachytherapy boost for locoregionally advanced cervical cancer... - Superficial endometrial spread of squamous cell cervical carcinoma: a diagnostic challenge at magnetic resonance imagingFelix Adler
Department of Radiology, University of California, San Francisco, CA 94143 0628, USA
J Comput Assist Tomogr 31:247-50. 2007.... - A cost-effectiveness analysis of prophylactic surgery versus gynecologic surveillance for women from hereditary non-polyposis colorectal cancer (HNPCC) FamiliesKathleen Y Yang
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, 1600 Divisadero St 4th Floor, San Francisco, CA 94115 1702, USA
Fam Cancer 10:535-43. 2011..Further, because risk-reducing surgery leads to both the lowest costs and the highest number of QALYs, it is a dominant strategy. Risk-reducing surgery is the most cost-effective option from a societal healthcare cost perspective... - Predictors of intensive care unit utilization in gynecologic oncology surgeryRachel Ruskin
Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, Helen Diller Family Cancer Center, University of California, CA, USA
Int J Gynecol Cancer 21:1336-42. 2011..The objectives of the study were to examine factors predicting intensive care unit (ICU) admission after surgery for gynecologic cancer and to determine the impact of ICU admission on survival... - Decidualized endometrioma during pregnancy: recognizing an imaging mimic of ovarian malignancyLiina Poder
Department of Radiology, University of California San Francisco, San Francisco, CA 94143 0628, USA
J Comput Assist Tomogr 32:555-8. 2008.... - A comparison of the cyclic variation in serum levels of CA125 across the menstrual cycle using two commercial assaysMonica R McLemore
School of Nursing, Department of Physiological Nursing, University of California, San Francisco, CA 94117, USA
Biol Res Nurs 14:250-6. 2012..The purpose of this study was to determine if serum concentrations of CA125 differed across the three phases of the menstrual cycle in healthy, premenopausal women using two commercially available assays... - An economic analysis of robotic versus laparoscopic surgery for endometrial cancer: costs, charges and reimbursements to hospitals and professionalsPavithra Venkat
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA 94143, USA
Gynecol Oncol 125:237-40. 2012..To determine the actual costs, charges, and reimbursements associated with robotic vs. laparoscopic surgery for endometrial cancer... - Squamous metaplasia of the ovarian surface epithelium and subsurface fibrosis: distinctive pathologic findings in the ovaries and fallopian tubes of patients on peritoneal dialysisElizabeth M Hosfield
Department of Pathology, University of California, San Francisco, California 94143, USA
Int J Gynecol Pathol 27:465-74. 2008..Dialysis-associated changes involving the ovary and fallopian tube form a mechanical barrier that could contribute to the low rate of fertility in peritoneal dialysis patients... - Small cell carcinoma of the cervix: treatment and survival outcomes of 188 patientsJoshua G Cohen
Division of Gynecologic Oncology, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA
Am J Obstet Gynecol 203:347.e1-6. 2010..To determine the clinicopathologic factors associated with survival in neuroendocrine small cell cervical cancer patients... - A randomized study of the effectiveness of a brief psychosocial intervention for women attending a gynecologic cancer clinicC Bethan Powell
Department of Obstetrics, Division of Gynecologic Oncology, Gynecology and Reproductive Sciences, UCSF, Helen Diller Family Comprehensive Cancer Center, San Francisco, CA 94143, USA
Gynecol Oncol 111:137-43. 2008..While there are many psychosocial interventions for cancer patients, few are brief in nature. The aim of this study was to investigate the usefulness of a single-visit psychosocial intervention for gynecologic cancer patients... - Epidemiological and genetic factors associated with ovarian cancerMonica R McLemore
Department of Physiologic Nursing, School of Nursing, University of California, San Francisco, 520 Frederick St, 31, San Francisco, CA 94117, USA
Cancer Nurs 32:281-8; quiz 289-90. 2009..The article concludes with a discussion of how oncology nurses can apply this information to improve patient care... - Ovarian pathology in risk-reducing salpingo-oophorectomies from women with BRCA mutations, emphasizing the differential diagnosis of occult primary and metastatic carcinomaJoseph T Rabban
Department of Pathology, University of California, M 551 San Francisco, California 94143, USA
Am J Surg Pathol 33:1125-36. 2009.... - COMT polymorphisms affecting protein expression are risk factors for endometrial cancerHiroshi Hirata
Department of Urology, Veterans Affairs Medical Center and University of California at San Francisco, San Francisco, California 94121, USA
Mol Carcinog 47:768-74. 2008..This is the first study demonstrating that polymorphisms in COMT codon 62 and codon 158 altered protein expression levels in EC, suggesting that they may be risk factors for EC in Caucasians... - Symptom management in gynecologic malignanciesCarolyn Casey
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA, USA
Expert Rev Anticancer Ther 11:1077-89. 2011..Literature regarding epidemiology, assessment and management of pain, fatigue, nausea/vomiting, lymphedema, ascites, depression, anxiety and sexual dysfunction in gynecologic oncology patients will be reviewed in this article... - CYP1A1, SULT1A1, and SULT1E1 polymorphisms are risk factors for endometrial cancer susceptibilityHiroshi Hirata
Department of Urology, University of California at San Francisco, San Francisco, CA 94121, USA
Cancer 112:1964-73. 2008..The authors hypothesized that single nucleotide polymorphisms (single nucleotide polymorphisms) of CYP1A1, CYP1A2, CYP1B1, CYP17, SULT1A1, SULT1E1, and SHBG genes may be risk factors for endometrial cancer... - Prophylactic surgery to reduce the risk of gynecologic cancers in the Lynch syndromeKathleen M Schmeler
Department of Gynecologic Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77230-1439, USA
N Engl J Med 354:261-9. 2006..CONCLUSIONS: These findings suggest that prophylactic hysterectomy with bilateral salpingo-oophorectomy is an effective strategy for preventing endometrial and ovarian cancer in women with the Lynch syndrome... - Society of Gynecologic Oncologists Education Committee statement on risk assessment for inherited gynecologic cancer predispositionsJohnathan M Lancaster
H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
Gynecol Oncol 107:159-62. 2007..This commentary provides guidance on identification of patients who may benefit from hereditary cancer risk assessment for Hereditary Breast/Ovarian Cancer and the Lynch/Hereditary Non-Polyposis Colorectal Cancer syndrome... - Magnetic resonance imaging of ovarian cancer arising in endometriomasTroy T Wu
Keck School of Medicine, University of Southern California, Los Angeles, CA 94143-0628, USA
J Comput Assist Tomogr 28:836-8. 2004.... - Risk-reducing salpingo-oophorectomy in BRCA mutation carriers: role of serial sectioning in the detection of occult malignancyC Bethan Powell
Gynecologic Oncology Program and Cancer Risk Program, University of California San Francisco Comprehensive Cancer Center, 2340 Sutter Street, Room N424, San Francisco, CA 94143, USA
J Clin Oncol 23:127-32. 2005..If confirmed, this finding will alter postoperative management because additional staging, chemotherapy, and follow-up may be necessary in affected women... - Gynecologic cancer as a "sentinel cancer" for women with hereditary nonpolyposis colorectal cancer syndromeKaren H Lu
Department of Gynecologic Oncology, Division of Surgery, University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4009, USA
Obstet Gynecol 105:569-74. 2005..The purpose of this study was to estimate whether women with hereditary nonpolyposis colorectal cancer syndrome who develop 2 primary cancers present with gynecologic or colon cancer as their "sentinel cancer.".. - Pathologic features of endometrial carcinoma associated with HNPCC: a comparison with sporadic endometrial carcinomaRussell R Broaddus
Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
Cancer 106:87-94. 2006..It was the purpose of this study to pathologically characterize a series of HNPCC associated endometrial carcinomas... - CT and MRI of adnexal masses in patients with primary nonovarian malignancyWei-Chao Chang
Department of Radiology, University of California San Francisco, Box 0628, M-372 505 Parnassus Ave, San Francisco, CA 94143-0628, USA
AJR Am J Roentgenol 186:1039-45. 2006..MRI may help characterize incidental benign entities such as endometriosis, fibroma, and peritoneal inclusion cysts... - Awareness of gynecologic surveillance in women from hereditary non-polyposis colorectal cancer familiesKathleen Yang
Division of Gynecologic Oncology, Department of Obstetrics, Gynecology, and Reproductive Sciences, UCSF Comprehensive Cancer Center, 1600 Divisadero St, 4th Floor, San Francisco, CA 94115, USA
Fam Cancer 5:405-9. 2006..CONCLUSIONS: While the effectiveness of surveillance remains in question, gynecologists can be a source of information regarding gynecologic cancer risk for women from HNPCC families... - Ovarian cancer. Clinical practice guidelines in oncologyRobert J Morgan
City of Hope Cancer Center, USA
J Natl Compr Canc Netw 4:912-39. 2006 - Cost-effectiveness analyses in gynecologic oncology: methodological quality and trendsMichael R Manuel
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California at San Francisco (UCSF, San Francisco, CA 94143, USA
Gynecol Oncol 93:1-8. 2004..Understanding the methodology of cost-effectiveness analysis is critical for researchers, editors, and readers to accurately interpret results of the growing body of CEA articles...