Kuan Ming Chen

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi Extensive mutagenesis experiments corroborate a structural model for the DNA deaminase domain of APOBEC3G
    Kuan Ming Chen
    University of Minnesota, Department of Biochemistry, Molecular Biology and Biophysics, Minneapolis, MN 55455, United States
    FEBS Lett 581:4761-6. 2007
  2. ncbi Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G
    Kuan Ming Chen
    Department of Biochemistry, Molecular Biology and Biophysics, of Minnesota, Minneapolis, Minnesota 55455, USA
    Nature 452:116-9. 2008
  3. ncbi Solution NMR structure of the N-terminal domain of the human DEK protein
    Matthew Devany
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Protein Sci 17:205-15. 2008
  4. ncbi An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model
    Elena Harjes
    Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, 55455, USA
    J Mol Biol 389:819-32. 2009

Collaborators

  • Reuben S Harris
  • Ferdinand Kappes
  • Elena Harjes
  • Hiroshi Matsuo
  • Matthew Devany
  • Yongjian Lu
  • Moshe Kotler
  • Keisuke Shindo
  • John D Gross
  • Phillip J Gross
  • Roni Nowarski
  • David M Markovitz

Detail Information

Publications4

  1. ncbi Extensive mutagenesis experiments corroborate a structural model for the DNA deaminase domain of APOBEC3G
    Kuan Ming Chen
    University of Minnesota, Department of Biochemistry, Molecular Biology and Biophysics, Minneapolis, MN 55455, United States
    FEBS Lett 581:4761-6. 2007
    ..These data corroborated an APOBEC2-based structural model for the catalytic domain of APOBEC3G indicating that most non-essential residues are solvent accessible and most essential residues cluster within the protein core...
  2. ncbi Structure of the DNA deaminase domain of the HIV-1 restriction factor APOBEC3G
    Kuan Ming Chen
    Department of Biochemistry, Molecular Biology and Biophysics, of Minnesota, Minneapolis, Minnesota 55455, USA
    Nature 452:116-9. 2008
    ..The structure of the APOBEC3G catalytic domain will help us to understand functions of other family members and interactions that occur with pathogenic proteins such as HIV-1 Vif...
  3. ncbi Solution NMR structure of the N-terminal domain of the human DEK protein
    Matthew Devany
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Protein Sci 17:205-15. 2008
    ..Our study illustrates a new structural variant and reveals novel dsDNA-binding properties for proteins containing the SAP/SAF motif...
  4. ncbi An extended structure of the APOBEC3G catalytic domain suggests a unique holoenzyme model
    Elena Harjes
    Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, 55455, USA
    J Mol Biol 389:819-32. 2009
    ....