Jian Fu Chen

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling
    Jianfu Chen
    Howard Hughes Medical Institute, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Children s Hospital Colorado, Aurora, CO 80045, USA
    Genes Dev 26:803-15. 2012
  2. pmc Transgenic overexpression of miR-133a in skeletal muscle
    Zhongliang Deng
    Department of Orthopaedic Surgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, PR China
    BMC Musculoskelet Disord 12:115. 2011
  3. ncbi Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size
    Jian Fu Chen
    1 Howard Hughes Medical Institute, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Children s Hospital Colorado, Aurora, Colorado 80045, USA 2 Department of Genetics, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, USA
    Nat Commun 5:3885. 2014

Collaborators

Detail Information

Publications3

  1. pmc The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling
    Jianfu Chen
    Howard Hughes Medical Institute, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Children s Hospital Colorado, Aurora, CO 80045, USA
    Genes Dev 26:803-15. 2012
    ..Thus, mLin41 acts as a temporal regulator to promote neural progenitor cell maintenance, not via the regulation of AGO2 stability, but through FGF signaling...
  2. pmc Transgenic overexpression of miR-133a in skeletal muscle
    Zhongliang Deng
    Department of Orthopaedic Surgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, PR China
    BMC Musculoskelet Disord 12:115. 2011
    ....
  3. ncbi Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size
    Jian Fu Chen
    1 Howard Hughes Medical Institute, Department of Pediatrics, University of Colorado Anschutz Medical Campus, Children s Hospital Colorado, Aurora, Colorado 80045, USA 2 Department of Genetics, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, USA
    Nat Commun 5:3885. 2014
    ..Our results suggest that Wdr62 interacts with Aurora A to control mitotic progression, and loss of these interactions leads to mitotic delay and cell death of NPCs, which could be a potential cause of human microcephaly. ..