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nuclear export signals
Genomes and Genes
Jau Nian Chen
University of California
Huang H, Zhang B, Hartenstein P, Chen J, Lin S. NXT2 is required for embryonic heart development in zebrafish. BMC Dev Biol. 2005;5:7
..The defects could be reproduced by morpholino anti-sense oligo knockdown of NXT2. NXT2 has a critical role in maintaining morphogenetic integrity of embryonic heart in vertebrate species. ..
Chen J, Fishman M. Genetics of heart development. Trends Genet. 2000;16:383-8
..Mutational analysis in mice and, as particular focus of this review, in zebrafish, reveals the additional genes brought into play to fashion these evolutionarily 'new' organotypic components. ..
Cavanaugh A, Huang J, Chen J. Two developmentally distinct populations of neural crest cells contribute to the zebrafish heart. Dev Biol. 2015;404:103-12
..These findings add to our understanding of the contribution of neural crest cells to the developing heart and provide insights into the requirement for these cells in cardiac maturation. ..
Lu F, Langenbacher A, Chen J. Tbx20 drives cardiac progenitor formation and cardiomyocyte proliferation in zebrafish. Dev Biol. 2017;421:139-148
Parvana A Hartenstein
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