Research Topics
| Hua ChenSummaryAffiliation: University of Houston Country: USA Publications
Research Grants
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Detail Information
Publications
The definition and prevalence of pediatric psychotropic polypharmacyHua Chen
College of Pharmacy, University of Houston TexasMedical Center, Houston, TX 77030, USA
Psychiatr Serv 62:1450-5. 2011..Using increasingly stringent criteria, this study evaluated the prevalence of psychotropic polypharmacy among children on the basis of duration of overlap between two or more psychotropic medications...- The impact of Medicare Part D on psychotropic utilization and financial burden for community-based seniorsHua Chen
College of Pharmacy, University of Houston, Houston, TX 77030, USA
Psychiatr Serv 59:1191-7. 2008..This study evaluated the impact of Medicare's new drug benefit (Part D) on utilization of psychotropic medications and the consequent financial burden for the elderly population... 
Prevalence and factors associated with self-reported vaccination rates among US adults at high risk of vaccine-preventable hepatitisHua Chen
Department of Clinical Sciences andAdministration, College of Pharmacy, University of Houston, Texas Medical Center, Houston, TX 77030, USA
Curr Med Res Opin 22:2489-96. 2006..Also, the association between vaccination rates and selected demographic, socio-economic characteristics and comorbidities was investigated...- Off-label use of second-generation antipsychotic agents among elderly nursing home residentsPravin Kamble
Department of Clinical Sciences and Administration, University of Houston Texas Medical Center, Houston, TX 77030, USA
Psychiatr Serv 61:130-6. 2010..This study examined off-label and evidence-based use of second-generation antipsychotic agents among elderly nursing home residents and factors associated with off-label use... - Antihypertensive drug use and the risk of dementia in patients with diabetes mellitusMichael L Johnson
Department of Clinical Sciences and Administration, Division of Pharmacy Administration and Public Health, University of Houston, College of Pharmacy, TX, USA
Alzheimers Dement 8:437-44. 2012..Diabetes and hypertension are independent risk factors for dementia, and hypertension may increase this risk in patients with diabetes. It is unclear whether antihypertensive drugs are associated with risk of dementia in these patients... - Risk of cerebrovascular adverse events in older adults using antipsychotic agents: a propensity-matched retrospective cohort studySandhya Mehta
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, Houston 77030 3407, USA
J Clin Psychiatry 71:689-98. 2010..To compare the risk of cerebrovascular adverse events with second-generation antipsychotic users versus those taking first-generation antipsychotics in community-dwelling older adults... - Risk of death in dual-eligible nursing home residents using typical or atypical antipsychotic agentsRajender R Aparasu
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, 1441 Moursund Street, Houston, TX 77030 3407, USA
Med Care 50:961-9. 2012..Antipsychotic use among dual-eligible nursing home residents is a concern for cost and safety considerations... - Risk of falls and fractures in older adults using atypical antipsychotic agents: a propensity score-adjusted, retrospective cohort studySatabdi Chatterjee
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, Houston, Texas, USA
Am J Geriatr Pharmacother 10:83-94. 2012..However, none of the studies assessed the comparative safety profiles of atypical agents with respect to falls and fractures... - Risk factors for dementia in patients over 65 with diabetesNiraj M Parikh
College of Pharmacy, University of Houston, TX, USA
Int J Geriatr Psychiatry 26:749-57. 2011..This study identified factors in patients with diabetes associated with risk of developing dementia... - Risk of serious cardiac events in older adults using antipsychotic agentsSandhya Mehta
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, Houston, USA
Am J Geriatr Pharmacother 9:120-32. 2011..Few epidemiologic studies have evaluated the risk of serious cardiovascular-related events in typical and atypical antipsychotic users... - Hospitalization risk associated with typical and atypical antipsychotic use in community-dwelling elderly patientsRajender R Aparasu
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, Houston, Texas 77030, USA
Am J Geriatr Pharmacother 6:198-204. 2008..However, few studies have examined the impact of typical and atypical antipsychotic use on all-cause hospitalization in the elderly population... - Risk of falls and fractures in older adults using antipsychotic agents: a propensity-matched retrospective cohort studySandhya Mehta
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, Houston, Texas 77030 3407, USA
Drugs Aging 27:815-29. 2010..Very few studies have compared the risk of falls and fractures among older adults using typical and atypical agents and none of the studies have evaluated differential risk across antipsychotic classes... - Determinants of atypical antipsychotic use among antipsychotic users in community-dwelling elderly, 1996-2004Elda Jano
College of Pharmacy, University of Houston, Texas Medical Center, Houston, TX 77030, USA
Curr Med Res Opin 24:709-16. 2008..This study examined the determinants of atypical antipsychotic use among antipsychotic users in community-dwelling elderly in the United States... - Effect of certain angiotensin-converting enzyme inhibitors on mortality in heart failure: a multiple-propensity analysisAbhishek S Chitnis
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, 1441 Moursund St, Houston, TX, USA
Res Social Adm Pharm 8:145-56. 2012..There is a substantial evidence about efficacy of angiotensin-converting enzyme inhibitors (ACEIs) in heart failure (HF); however, there is no conclusive evidence on the relative effectiveness of individual ACEIs... - Economic benefit of appropriate timing of vancomycin prophylaxis in patients undergoing cardiovascular surgeryKevin W Garey
University of Houston College of Pharmacy, Houston, Texas, USA
Pharmacotherapy 28:699-706. 2008.... - Timing of vancomycin prophylaxis for cardiac surgery patients and the risk of surgical site infectionsKevin W Garey
University of Houston College of Pharmacy, Department of Clinical Sciences and Administration, Houston, TX 77030 3047, USA
J Antimicrob Chemother 58:645-50. 2006..The objective of the present study was to assess the effect of vancomycin prophylaxis timing in relation to the first surgical incision on the incidence of SSI... - Comparative Risk of Cerebrovascular Adverse Events in Community-Dwelling Older Adults using Risperidone, Olanzapine and Quetiapine : A Multiple Propensity Score-Adjusted Retrospective Cohort StudySatabdi Chatterjee
Department of Clinical Sciences and Administration, College of Pharmacy, Texas Medical Center, University of Houston, 1441 Moursund Street, Houston, TX, 77030, USA
Drugs Aging 29:807-17. 2012..However, limited evidence exists regarding comparative cerebrovascular profiles of individual atypical agents, particularly in community settings... - Extent of functional impairment in children and adolescents with depressionSaurabh Nagar
University of Houston, Texas Medical Center, Houston, TX 77030 3407, USA
Curr Med Res Opin 26:2057-64. 2010..This study examined the extent of functional impairment in children and adolescents aged 5 to 17 years with depression based on 2005-2006 Medical Expenditure Panel Survey (MEPS) data... - Antipsychotic drug use among elderly nursing home residents in the United StatesPravin Kamble
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Houston, Texas 77030, USA
Am J Geriatr Pharmacother 6:187-97. 2008..However, few studies have examined antipsychotic utilization patterns in nursing home residents in the United States since the introduction of atypical agents in the 1990s... 
Correlates of HIV knowledge and sexual risk behaviors among female military personnelE James Essien
University of Houston, Texas Medical Center, Houston, TX 77030, USA
AIDS Behav 14:1401-14. 2010..05) associated with number of children, annual income, and number of sexual partners. Data indicates the importance of incorporating these predictor variables into intervention designs...- The effect of adjunctive mood stabilizers on antipsychotic utilization pattern and health resource utilization for Medicaid enrollees with schizophreniaHua Chen
Department of Clinical Sciences and Administration, University of Houston, Houston, TX, USA
Curr Med Res Opin 23:1351-65. 2007..Prescribing adjunctive mood stabilizers to manage schizophrenia is prevalent, despite the lack of substantial evidence to support the long-term use of this treatment regimen... - Use of antipsychotics among elderly nursing home residents with dementia in the US: an analysis of National Survey DataPravin Kamble
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, Houston, Texas, USA
Drugs Aging 26:483-92. 2009..However, recent data suggest that the risk of adverse effects may offset the benefits of atypical agents in patients with dementia... - Antipsychotic utilization and expenditure trends among elderly personsElda Jano
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, Texas Medical Center, 1441 Moursund St, Houston, TX 77030-3407, USA
Psychiatr Serv 58:1400. 2007 - High- versus low-dose fluconazole therapy for empiric treatment of suspected invasive candidiasis among high-risk patients in the intensive care unit: a cost-effectiveness analysisHua Chen
University of Houston, Houston, TX, USA
Curr Med Res Opin 23:1057-65. 2007..However, empiric high-dose fluconazole is not currently recommended and may result in higher drug costs and toxicity... - Off-label use of antidepressant, anticonvulsant, and antipsychotic medications among Georgia medicaid enrollees in 2001Hua Chen
Department of Clinical Sciences and Administration, College of Pharmacy, University of Houston, USA
J Clin Psychiatry 67:972-82. 2006..Further research to study the effects of off-label use among this high risk subpopulation may be an important step toward defining the scope of and potential for such use... - Significance of hepatitis B virus surface antigen, hepatitis C virus expression in hepatocellular carcinoma and pericarcinomatous tissuesShi Ying Xuan
College of Medicine and Pharmaceutics, Ocean University of China, 5 Yushan Road, Qingdao 266003, Shandong Province, China
World J Gastroenterol 13:1870-4. 2007.... - An epidemiological investigation of off-label anticonvulsant drug use in the Georgia Medicaid populationHua Chen
Pharmacy Care Administration Graduate Program, University of Georgia, Athens, GA 30602, USA
Pharmacoepidemiol Drug Saf 14:629-38. 2005..CONCLUSIONS: The anticonvulsant off-label use in the Georgia Medicaid population is very high (71%). Only a modest proportion of these off-label uses are supported by evidence from controlled trials...
Research Grants
- The Impact of the FDA Antidepressant Black Box Warning on Psychiatric PracticeHua Chen; Fiscal Year: 2007..The study findings will also be a good reference for the policy makers when new black box warning is considered for psychiatric drugs other than antidepressants. ..