Guang Hong Chen

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc Time-resolved interventional cardiac C-arm cone-beam CT: an application of the PICCS algorithm
    Guang Hong Chen
    Department of Medical Physics, Radiology, Human Oncology, University ofWisconsin Madison, 53792, USA
    IEEE Trans Med Imaging 31:907-23. 2012
  2. pmc Small-angle scattering computed tomography (SAS-CT) using a Talbot-Lau interferometerand a rotating anode x-ray tube:theory and experiments
    Guang Hong Chen
    Department of Medical Physics, University of Wisconsin Madison, WI 53705, USA
    Opt Express 18:12960-70. 2010
  3. pmc Temporal resolution improvement using PICCS in MDCT cardiac imaging
    Guang Hong Chen
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    Med Phys 36:2130-5. 2009
  4. pmc Streaking artifacts reduction in four-dimensional cone-beam computed tomography
    Shuai Leng
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53792, USA
    Med Phys 35:4649-59. 2008
  5. ncbi request reprint Fan-beam and cone-beam image reconstruction via filtering the backprojection image of differentiated projection data
    Tingliang Zhuang
    Department of Medical Physics, University of Wisconsin Madison, WI 53704, USA
    Phys Med Biol 49:5489-503. 2004
  6. ncbi request reprint Exact fan-beam image reconstruction algorithm for truncated projection data acquired from an asymmetric half-size detector
    Shuai Leng
    Department of Medical Physics, University of Wisconsin Madison, 53704, USA
    Phys Med Biol 50:1805-20. 2005
  7. ncbi request reprint Development and evaluation of an exact fan-beam reconstruction algorithm using an equal weighting scheme via locally compensated filtered backprojection (LCFBP)
    Guang Hong Chen
    Department of Medical Physics, University of Wisconsin, Madison, Wisconsin 53704, USA
    Med Phys 33:475-81. 2006
  8. ncbi request reprint A shift-invariant filtered backprojection (FBP) cone-beam reconstruction algorithm for the source trajectory of two concentric circles using an equal weighting scheme
    Tingliang Zhuang
    Department of Medical Physics, University of Wisconsin Madison, Madison, WI 53704, USA
    Phys Med Biol 51:3189-210. 2006
  9. pmc High temporal resolution and streak-free four-dimensional cone-beam computed tomography
    Shuai Leng
    Department of Medical Physics, University of Wisconsin Madison, WI 53792 1590, USA
    Phys Med Biol 53:5653-73. 2008
  10. ncbi request reprint A novel extension of the parallel-beam projection-slice theorem to divergent fan-beam and cone-beam projections
    Guang Hong Chen
    Department of Medical Physics, University of Wisconsin in Madison, Madison, Wisconsin 53704, USA
    Med Phys 32:654-65. 2005

Collaborators

Detail Information

Publications45

  1. pmc Time-resolved interventional cardiac C-arm cone-beam CT: an application of the PICCS algorithm
    Guang Hong Chen
    Department of Medical Physics, Radiology, Human Oncology, University ofWisconsin Madison, 53792, USA
    IEEE Trans Med Imaging 31:907-23. 2012
    ..A canine animal model scanned in vivo was used to further validate the method...
  2. pmc Small-angle scattering computed tomography (SAS-CT) using a Talbot-Lau interferometerand a rotating anode x-ray tube:theory and experiments
    Guang Hong Chen
    Department of Medical Physics, University of Wisconsin Madison, WI 53705, USA
    Opt Express 18:12960-70. 2010
    ..Next, a Talbot-Lau interferometer and a rotating-anode x-ray tube were used to implement SAS-CT. A physical phantom and human breast tissue sample were used to demonstrate the reconstructed SAS-CT image volumes...
  3. pmc Temporal resolution improvement using PICCS in MDCT cardiac imaging
    Guang Hong Chen
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    Med Phys 36:2130-5. 2009
    ..This method also enables dual-source MDCT scanner to achieve higher temporal resolution without further hardware modifications...
  4. pmc Streaking artifacts reduction in four-dimensional cone-beam computed tomography
    Shuai Leng
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53792, USA
    Med Phys 35:4649-59. 2008
    ..At the same time, a temporal gating window as narrow as 100 ms was utilized. Compared to the conventional 4D CBCT reconstruction, streaking artifacts were reduced by 60% to 70%...
  5. ncbi request reprint Fan-beam and cone-beam image reconstruction via filtering the backprojection image of differentiated projection data
    Tingliang Zhuang
    Department of Medical Physics, University of Wisconsin Madison, WI 53704, USA
    Phys Med Biol 49:5489-503. 2004
    ..Numerical simulations were conducted to validate the new reconstruction scheme for the fan-beam case...
  6. ncbi request reprint Exact fan-beam image reconstruction algorithm for truncated projection data acquired from an asymmetric half-size detector
    Shuai Leng
    Department of Medical Physics, University of Wisconsin Madison, 53704, USA
    Phys Med Biol 50:1805-20. 2005
    ..The most important characteristic of the proposed reconstruction scheme is that an explicit data rebinning process is not introduced. Numerical simulations were conducted to validate the new reconstruction algorithm...
  7. ncbi request reprint Development and evaluation of an exact fan-beam reconstruction algorithm using an equal weighting scheme via locally compensated filtered backprojection (LCFBP)
    Guang Hong Chen
    Department of Medical Physics, University of Wisconsin, Madison, Wisconsin 53704, USA
    Med Phys 33:475-81. 2006
    ..Both phantom data and clinical data were utilized to validate the algorithm and demonstrate the superior noise properties of the new algorithm...
  8. ncbi request reprint A shift-invariant filtered backprojection (FBP) cone-beam reconstruction algorithm for the source trajectory of two concentric circles using an equal weighting scheme
    Tingliang Zhuang
    Department of Medical Physics, University of Wisconsin Madison, Madison, WI 53704, USA
    Phys Med Biol 51:3189-210. 2006
    ..Numerical simulations are presented to validate the reconstruction algorithm and demonstrate the dose advantage of the equal weighting scheme...
  9. pmc High temporal resolution and streak-free four-dimensional cone-beam computed tomography
    Shuai Leng
    Department of Medical Physics, University of Wisconsin Madison, WI 53792 1590, USA
    Phys Med Biol 53:5653-73. 2008
    ..This feature of PICCS breaks the connection between the temporal resolution and streaking artifacts' level in 4D CBCT. Numerical simulations and experimental phantom studies have been conducted to validate the method...
  10. ncbi request reprint A novel extension of the parallel-beam projection-slice theorem to divergent fan-beam and cone-beam projections
    Guang Hong Chen
    Department of Medical Physics, University of Wisconsin in Madison, Madison, Wisconsin 53704, USA
    Med Phys 32:654-65. 2005
    ..Numerical simulations are performed to verify the generalized projection-slice theorem by using a disc phantom in the fan-beam case...
  11. ncbi request reprint A local region of interest image reconstruction via filtered backprojection for fan-beam differential phase-contrast computed tomography
    Zhihua Qi
    Department of Medical Physics, University of Wisconsin in Madison, 600 Highland Avenue, Madison, WI 53792 1590, USA
    Phys Med Biol 52:N417-23. 2007
    ..Numerical simulations have been conducted to validate the image reconstruction algorithm...
  12. pmc Noise spatial nonuniformity and the impact of statistical image reconstruction in CT myocardial perfusion imaging
    Pascal Thériault Lauzier
    Department of Medical Physics, University of Wisconsin Madison, Madison, WI, USA
    Med Phys 39:4079-92. 2012
    ..2) To demonstrate that statistical image reconstruction (SIR) algorithms can be a potential solution to address the nonuniform spatial noise distribution problem and can also lead to radiation dose reduction in the context of CT MPI...
  13. pmc Multicontrast x-ray computed tomography imaging using Talbot-Lau interferometry without phase stepping
    Nicholas Bevins
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    Med Phys 39:424-8. 2012
    ....
  14. ncbi request reprint Temporal resolution improvement in cardiac CT using PICCS (TRI-PICCS): performance studies
    Jie Tang
    Department of Medical Physics, University of Wisconsin Madison, 53705, USA
    Med Phys 37:4377-88. 2010
    ....
  15. ncbi request reprint A new data consistency condition for fan-beam projection data
    Guang Hong Chen
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53792, USA
    Med Phys 32:961-7. 2005
    ..Numerical simulations are performed to validate the new FDCC in correcting ring artifacts caused by malfunctioning detector cells...
  16. pmc Quantitative imaging of electron density and effective atomic number using phase contrast CT
    Zhihua Qi
    Department of Medical Physics, University of Wisconsin Madison, WI 53705, USA
    Phys Med Biol 55:2669-77. 2010
    ..The presented method will provide insight into the technique of material separation and find its use in medical and industrial applications...
  17. pmc Performance comparison between total variation (TV)-based compressed sensing and statistical iterative reconstruction algorithms
    Jie Tang
    Department of Medical Physics, University of Wisconsin Madison, Madison, WI 53705, USA
    Phys Med Biol 54:5781-804. 2009
    ....
  18. pmc Grating-based phase contrast tomosynthesis imaging: Proof-of-concept experimental studies
    Ke Li
    Department of Medical Physics, University of Wisconsin Madison, 1111 Highland Avenue, Madison, Wisconsin 53705
    Med Phys 41:011903. 2014
    ..The method shows promise in improving the visibility of several low-density materials and therefore merits further investigation. ..
  19. pmc Spatial resolution characterization of differential phase contrast CT systems via modulation transfer function (MTF) measurements
    Ke Li
    Department of Medical Physics, University of Wisconsin Madison, 1111 Highland Avenue, Madison, WI 53705, USA
    Phys Med Biol 58:4119-35. 2013
    ..An effective MTF was introduced and experimentally estimated to describe the impact of the Talbot-Lau interferometer on the system MTF...
  20. pmc Temporally targeted imaging method applied to ECG-gated computed tomography: preliminary phantom and in vivo experience
    Brian E Nett
    Department of Medical Physics, University of Wisconsin Madison, J5 M174, Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 1590, USA
    Acad Radiol 15:93-106. 2008
    ..In gated cardiac computed tomography (CT) scans improved temporal resolution directly translates into a reduction in motion artifacts for rapidly moving objects such as the coronary arteries...
  21. pmc Fundamental relationship between the noise properties of grating-based differential phase contrast CT and absorption CT: theoretical framework using a cascaded system model and experimental validation
    Ke Li
    Department of Medical Physics, University of Wisconsin Madison, Madison, WI 53705, USA
    Med Phys 40:021908. 2013
    ..The purpose of this paper is to investigate these relationships...
  22. pmc Abdominal CT with model-based iterative reconstruction (MBIR): initial results of a prospective trial comparing ultralow-dose with standard-dose imaging
    Perry J Pickhardt
    Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
    AJR Am J Roentgenol 199:1266-74. 2012
    ..The purpose of this study was to report preliminary results of an ongoing prospective trial of ultralow-dose abdominal MDCT...
  23. pmc Interior tomography in x-ray differential phase contrast CT imaging
    Pascal Thériault Lauzier
    Department of Medical Physics, University of Wisconsin Madison, Madison, WI 53705, USA
    Phys Med Biol 57:N117-30. 2012
    ..In both cases, the root mean square error is reduced by an order of magnitude with respect to the truncated analytic reconstructions. Truncation artifacts observed in the latter reconstructions are eliminated using the POCS algorithm...
  24. pmc Time-resolved cardiac interventional cone-beam CT reconstruction from fully truncated projections using the prior image constrained compressed sensing (PICCS) algorithm
    Pascal Thériault Lauzier
    Department of Medical Physics, University of Wisconsin Madison, Madison, WI, USA
    Phys Med Biol 57:2461-76. 2012
    ..3) This study showed evidence that accurate interior tomography with an undersampled acquisition is possible for realistic objects if a prior image with minimal artifacts is available...
  25. pmc Extraction of tumor motion trajectories using PICCS-4DCBCT: a validation study
    Zhihua Qi
    Department of Medical Physics, University of Wisconsin Madison, Madison, WI, USA
    Med Phys 38:5530-8. 2011
    ....
  26. pmc Perfusion measurements by micro-CT using prior image constrained compressed sensing (PICCS): initial phantom results
    Brian E Nett
    Department of Medical Physics, University of Wisconsin Madison, Madison, WI, USA
    Phys Med Biol 55:2333-50. 2010
    ..Sample perfusion maps using a deconvolution-based perfusion analysis are included to demonstrate the improvement in image quality using the PICCS algorithm...
  27. ncbi request reprint A new framework of image reconstruction from fan beam projections
    Guang Hong Chen
    Department of Medical Physics, University of Wisconsin, Madison, Wisconsin 53792, USA
    Med Phys 30:1151-61. 2003
    ..It results in a new algorithm for the sequential reconstruction of a ROI with a general normalized weighting function...
  28. pmc Radiation dose reduction in time-resolved CT angiography using highly constrained back projection reconstruction
    Mark Supanich
    Department of Medical Physics, University of Wisconsin in Madison, 1111 Highland Avenue, Madison, WI, 53705, USA
    Phys Med Biol 54:4575-93. 2009
    ..Experimental results demonstrated that a factor of 6-8 times radiation dose reduction is possible when the HYPR algorithm is applied to time-resolved CTA exams...
  29. pmc Prior image constrained compressed sensing: implementation and performance evaluation
    Pascal Thériault Lauzier
    Medical Physics Department, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    Med Phys 39:66-80. 2012
    ..The purpose is to study and compare the performance of each implementation, as well as to evaluate the performance of the PICCS objective function with respect to image quality...
  30. doi request reprint Reduced image noise at low-dose multidetector CT of the abdomen with prior image constrained compressed sensing algorithm
    Meghan G Lubner
    Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 31 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
    Radiology 260:248-56. 2011
    ..To assess the effect of prior image constrained compressed sensing (PICCS) on noise reduction and image quality at low-dose computed tomography (CT)...
  31. pmc Prior image constrained scatter correction in cone-beam computed tomography image-guided radiation therapy
    Stephen Brunner
    Department of Medical Physics, University of Wisconsin Madison, Madison, WI 53705, USA
    Phys Med Biol 56:1015-30. 2011
    ..Results show that the proposed scatter correction algorithm using a prior image with low scatter artifacts can substantially mitigate scatter-induced shading artifacts in both full-fan and half-fan modes...
  32. ncbi request reprint Statistical model based iterative reconstruction (MBIR) in clinical CT systems. Part II. Experimental assessment of spatial resolution performance
    Ke Li
    Department of Medical Physics, University of Wisconsin Madison, 1111 Highland Avenue, Madison, Wisconsin 53705 and Department of Radiology, University of Wisconsin Madison, 600 Highland Avenue, Madison, Wisconsin 53792
    Med Phys 41:071911. 2014
    ....
  33. ncbi request reprint An alternative derivation of Katsevich's cone-beam reconstruction formula
    Guang Hong Chen
    Department of Medical Physics, University of Wisconsin, Madison, Wisconsin 53792, USA
    Med Phys 30:3217-26. 2003
    ..However, the data sufficiency conditions and the regularization scheme of singularities are different. A detailed comparison between these two methods is presented...
  34. pmc Characterization of statistical prior image constrained compressed sensing (PICCS): II. Application to dose reduction
    Pascal Thériault Lauzier
    Medical Physics Department, University of Wisconsin Madison, Madison, WI 53705, USA
    Med Phys 40:021902. 2013
    ..The purpose of this study is to characterize the effects of a statistical model of x-ray detection in the DR-PICCS framework and its impact on spatial resolution...
  35. pmc Performance studies of four-dimensional cone beam computed tomography
    Zhihua Qi
    Department of Medical Physics, University of Wisconsin Madison, WI 53705 2275, USA
    Phys Med Biol 56:6709-21. 2011
    ....
  36. pmc Scaling law for noise variance and spatial resolution in differential phase contrast computed tomography
    Guang Hong Chen
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53705, USA
    Med Phys 38:584-8. 2011
    ..The noise variance versus spatial resolution relationship in differential phase contrast (DPC) projection imaging and computed tomography (CT) are derived and compared to conventional absorption-based x-ray projection imaging and CT...
  37. pmc Statistical model based iterative reconstruction (MBIR) in clinical CT systems: experimental assessment of noise performance
    Ke Li
    Department of Medical Physics, University of Wisconsin Madison, 1111 Highland Avenue, Madison, Wisconsin 53705
    Med Phys 41:041906. 2014
    ..The purpose of this work is to experimentally assess the unique noise characteristics of MBIR using a state-of-the-art clinical CT system...
  38. ncbi request reprint Low dose dynamic CT myocardial perfusion imaging using a statistical iterative reconstruction method
    Yinghua Tao
    Department of Medical Physics, University of Wisconsin Madison, Madison, Wisconsin 53705
    Med Phys 41:071914. 2014
    ..The purpose of this study is to investigate the use of statistical iterative reconstruction to improve parametric maps of myocardial perfusion derived from a low tube current dynamic CT acquisition...
  39. pmc Characterization of statistical prior image constrained compressed sensing. I. Applications to time-resolved contrast-enhanced CT
    Pascal Thériault Lauzier
    Medical Physics Department, University of Wisconsin Madison, Madison, WI 53705, USA
    Med Phys 39:5930-48. 2012
    ..This paper investigates these properties in the clinical context of time-resolved contrast-enhanced CT...
  40. pmc Image reconstruction for fan-beam differential phase contrast computed tomography
    Guang Hong Chen
    Department of Medical Physics and Department of Radiology, University of Wisconsin in Madison, Madison, WI 53792 1590, USA
    Phys Med Biol 53:1015-25. 2008
    ..In this last case, the data are truncated from every view angle. Numerical simulations have been conducted to validate the new reconstruction formula...
  41. doi request reprint A simple technique for interventional tool placement combining fluoroscopy with interventional computed tomography on a C-arm system
    Brian E Nett
    Department of Medical Physics, University of Wisconsin Madison, School of Medicine and Public Health, Madison, Wisconsin 53705, USA
    Neurosurgery 67:ons49-56; discussion ons56-7. 2010
    ..Flat-panel cone-beam computed tomography (FP-CBCT) has recently been introduced as a clinical feature in neuroangiography radiographic C-arm systems...
  42. doi request reprint Correlation between human observer performance and model observer performance in differential phase contrast CT
    Ke Li
    Department of Medical Physics, University of Wisconsin Madison, 1111 Highland Avenue, Madison, Wisconsin 53705
    Med Phys 40:111905. 2013
    ..This work is an investigation of the effects of stochastic DPC-CT noise on the correlation of detection performance between model and human observers with signal-known-exactly (SKE) detection tasks...
  43. pmc Quantification of hepatic steatosis with dual-energy computed tomography: comparison with tissue reference standards and quantitative magnetic resonance imaging in the ob/ob mouse
    Nathan S Artz
    Department of Radiology, University of Wisconsin, Madison, WI 53705 2275, USA
    Invest Radiol 47:603-10. 2012
    ....
  44. doi request reprint Dual energy CT using slow kVp switching acquisition and prior image constrained compressed sensing
    Timothy P Szczykutowicz
    Department of Medical Physics, University of Wisconsin Madison, WI 53704, USA
    Phys Med Biol 55:6411-29. 2010
    ..In contrast, the slew rate should be high enough to obtain over 500 projections at each kVp for artifact-free reconstruction using an FBP-based DECT method...
  45. pmc Prior image constrained compressed sensing (PICCS): a method to accurately reconstruct dynamic CT images from highly undersampled projection data sets
    Guang Hong Chen
    Med Phys 35:660-3. 2008
    ..This undersampling factor implies a potential radiation dose reduction by a factor of 32 in myocardial CT perfusion imaging...

Research Grants6

  1. 3D Time-resolved Tomographic Interventional Platform
    Guang Hong Chen; Fiscal Year: 2004
    ....
  2. Integrated Tomosynthetic Perfusion and Cone-beam CT Imaging on a C-arm Gantry
    Guang Hong Chen; Fiscal Year: 2006
    ..The new interventional platform will not only benefit those at research centers, but also will enable image-guided interventional stroke treatments for hospitals without advanced imaging facilities. ..
  3. Integrated Tomosynthetic Perfusion and Cone-beam CT Imaging on a C-arm Gantry
    Guang Hong Chen; Fiscal Year: 2007
    ..The new interventional platform will not only benefit those at research centers, but also will enable image-guided interventional stroke treatments for hospitals without advanced imaging facilities. ..
  4. Integrated Tomosynthetic Perfusion and Cone-beam CT Imaging on a C-arm Gantry
    Guang Hong Chen; Fiscal Year: 2009
    ..The new interventional platform will not only benefit those at researchcenters,but also will enable image-guided interventional stroke treatmentsfor hospitals without advanced imaging facilities. ..
  5. Four Dimensional Cone Beam CT for Image-guided Radiation Therapy
    Guang Hong Chen; Fiscal Year: 2010
    ..This will find wide application in cancer treatment for the chest and upper abdomen, including cancer of either the lungs or liver. ..