Guang Chen

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Group SCAD regression analysis for microarray time course gene expression data
    LiFeng Wang
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Bioinformatics 23:1486-94. 2007
  2. ncbi Clustering of genes into regulons using integrated modeling-COGRIM
    Guang Chen
    Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Genome Biol 8:R4. 2007
  3. ncbi Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha
    Rana K Gupta
    Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Genes Dev 21:756-69. 2007
  4. ncbi The anti-apoptotic, glucocorticoid receptor cochaperone protein BAG-1 is a long-term target for the actions of mood stabilizers
    Rulun Zhou
    Laboratory of Molecular Pathophysiology, National Institute of Mental Health, Bethesda, Maryland 20852, USA
    J Neurosci 25:4493-502. 2005
  5. ncbi Defining the mammalian CArGome
    Qiang Sun
    Cardiovascular Research Institute, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Genome Res 16:197-207. 2006
  6. ncbi Systems biology-defined NF-kappaB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status
    Bin Yan
    Head and Neck Surgery Branch, NIDCD, National Institutes of Health, Bethesda, MD 20892, USA
    Genome Biol 9:R53. 2008
  7. ncbi BAG1 plays a critical role in regulating recovery from both manic-like and depression-like behavioral impairments
    Sungho Maeng
    Laboratory of Molecular Pathophysiology and Experimental Therapeutics, Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 105:8766-71. 2008

Collaborators

  • Xiaoxia Li
  • Christian J Stoeckert
  • Hongzhe Li
  • Shane T Jensen
  • Bin Yan
  • JOSEPH MIANO
  • Hong Fu
  • L Zhang
  • Rulun Zhou
  • Sungho Maeng
  • LiFeng Wang
  • Rana K Gupta
  • Peixiong Yuan
  • Husseini K Manji
  • Jing Du
  • Qiang Sun
  • John C Reed
  • Robert J Schloesser
  • Joshua G Hunsberger
  • Bruce McEwen
  • Yun Wang
  • Yanling Wei
  • Brandon Pearson
  • Joseph McCammon
  • Kiran Rafiq
  • Peter White
  • Nan Gao
  • Olga T Hardy
  • Klaus H Kaestner
  • John E Brestelli
  • Regina K Gorski
  • Yumei Yang
  • Xiaochun Long
  • Jeffrey W Streb
  • Jingshan Chen
  • Neil A Gray
  • Patricia Damschroder-Williams

Detail Information

Publications7

  1. ncbi Group SCAD regression analysis for microarray time course gene expression data
    LiFeng Wang
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Bioinformatics 23:1486-94. 2007
    ....
  2. ncbi Clustering of genes into regulons using integrated modeling-COGRIM
    Guang Chen
    Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Genome Biol 8:R4. 2007
    ..In these applications, we demonstrate the ability to predict gene-transcription factor interactions with reduced numbers of false-positive findings and to make predictions beyond what is obtained when single types of data are considered...
  3. ncbi Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha
    Rana K Gupta
    Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Genes Dev 21:756-69. 2007
    ..Together, these results indicate that HNF-4alpha is essential for the physiological expansion of adult beta-cell mass in response to increased metabolic demand...
  4. ncbi The anti-apoptotic, glucocorticoid receptor cochaperone protein BAG-1 is a long-term target for the actions of mood stabilizers
    Rulun Zhou
    Laboratory of Molecular Pathophysiology, National Institute of Mental Health, Bethesda, Maryland 20852, USA
    J Neurosci 25:4493-502. 2005
    ....
  5. ncbi Defining the mammalian CArGome
    Qiang Sun
    Cardiovascular Research Institute, University of Rochester School of Medicine, Rochester, NY 14642, USA
    Genome Res 16:197-207. 2006
    ..We suggest one function of SRF is that of an ancient master regulator of the actin cytoskeleton...
  6. ncbi Systems biology-defined NF-kappaB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status
    Bin Yan
    Head and Neck Surgery Branch, NIDCD, National Institutes of Health, Bethesda, MD 20892, USA
    Genome Biol 9:R53. 2008
    ..However, how NF-kappaB acts as a key regulatory node to modulate global gene expression, and contributes to the malignant heterogeneity of head and neck cancer, is not well understood...
  7. ncbi BAG1 plays a critical role in regulating recovery from both manic-like and depression-like behavioral impairments
    Sungho Maeng
    Laboratory of Molecular Pathophysiology and Experimental Therapeutics, Mood and Anxiety Disorders Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
    Proc Natl Acad Sci U S A 105:8766-71. 2008
    ..These data suggest that BAG1 plays a key role in affective resilience and in regulating recovery from both manic-like and depression-like behavioral impairments...