- A mutant form of the Neisseria gonorrhoeae pilus secretin protein PilQ allows increased entry of heme and antimicrobial compoundsChing Ju Chen
Department of Medicine Department of Microbiology and Immunology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7031, USA
J Bacteriol 186:730-9. 2004..These results show that PilQ forms a channel that allows entry of heme and certain antimicrobial compounds and that a gain-of function point mutation in pilQ results in TonB-independent, PilT-dependent increase of entry...
- Point mutations in HpuB enable gonococcal HpuA deletion mutants to grow on hemoglobinChing-ju Chen
Department of Medicine, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599, USA
J Bacteriol 184:420-6. 2002..Thus, HpuB point mutants internalized heme in the absence of HpuA despite reduced binding of Hb. HpuA facilitated Hb binding and was important in allowing use of heme from Hb for growth...