Research Topics
Species | B ChenSummaryAffiliation: University at Buffalo Country: USA Publications
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Detail Information
Publications
The expression of the HSP90 gene in response to winter and summer diapauses and thermal-stress in the onion maggot, Delia antiquaB Chen
Laboratory of Applied Entomology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Tokyo, Japan
Insect Mol Biol 14:697-702. 2005..These results suggest that the development and physiology of summer- and winter-diapauses, as monitored via variation in HSP90 transcript levels, can be substantial different...
DaTrypsin, a novel clip-domain serine proteinase gene up-regulated during winter and summer diapauses of the onion maggot, Delia antiquaBin Chen
Laboratory of Applied Entomology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113 8657, Japan
Gene 347:115-23. 2005..It may participate in the host's immune defense and/or maintain the developmental status in the diapausing pupae...
The HSP90 family of genes in the human genome: insights into their divergence and evolutionBin Chen
Department of Biological Sciences, The State University of New York at Buffalo, NY 14260, USA
Genomics 86:627-37. 2005..Phylogenetic analyses based on both nucleotide and protein data demonstrated that HSP90(AA+AB+B) formed a monophyletic clade, whereas TRAP is a relatively distant paralogue of this clade...
Upregulation of a desaturase is associated with the enhancement of cold hardiness in the onion maggot, Delia antiquaTakumi Kayukawa
Laboratory of Applied Entomology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113 8657, Japan
Insect Biochem Mol Biol 37:1160-7. 2007..These findings suggest that the increase in the expression of Dadesat contributes to enhanced cold hardiness in D. antiqua through the production of these unsaturated fatty acids...
Expression of mRNA for the t-complex polypeptide-1, a subunit of chaperonin CCT, is upregulated in association with increased cold hardiness in Delia antiquaTakumi Kayukawa
Laboratory of Applied Entomology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113-8657, Japan
Cell Stress Chaperones 10:204-10. 2005..These findings suggest that the upregulation of DaTCP-1 expression is related to enhanced cold hardiness in D antiqua. The upregulation of CCT in response to low temperature in an organism other than the yeast is newly reported...
Cloning and characterization of the HSP70 Gene, and its expression in response to diapauses and thermal stress in the onion maggot, Delia antiquaBin Chen
Laboratory of Applied Entomology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113 8657, Japan
J Biochem Mol Biol 39:749-58. 2006..HSP70 expression was low in non-diapausing pupae but was up-regulated following cold- and heatstresses. Heat-stress gradually increased the mRNA level with time whereas cold-stress gradually decreased levels after an initial increase...
In vivo electroporation of DNA into the wing epidermis of the butterfly, Bicyclus anynanaKyle Golden
Department of Biological Sciences, University at Buffalo, Buffalo, NY 14260, USA
J Insect Sci 7:1-8. 2007....
Gene targeting using a promoterless gene trap vector ("targeted trapping") is an efficient method to mutate a large fraction of genesRoland H Friedel
Department of Biological Sciences, Howard Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 102:13188-93. 2005..The simplicity and high efficiency of the method facilitate systematic targeting of a large fraction of the genome by individual investigators and large-scale consortia alike...
Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organismsBin Chen
School of Life Sciences, Southwest University, Chongqing 400715, P R China
BMC Genomics 7:156. 2006....
Role of hunchback in segment patterning of Locusta migratoria manilensis revealed by parental RNAiZheng-Bo He
Genetic Engineering Research Center, Chongqing University, Chongqing Engineering and Technology Center of Fungal Insecticide, Chongqing 400044, China
Dev Growth Differ 48:439-45. 2006..These findings suggest a more extensive role for L. migratoria manilensis hunchback in anterior patterning than those described in Drosophila...
Potential of endogenous estrogen receptor beta to influence the selective ER modulator ERbeta complexBin Chen
Robert H. Lurie Comprehensive Cancer Center, The Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Int J Oncol 27:327-35. 2005..We conclude that endogenous ERbeta may not play a dominant role in the modulation of the tamoxifen ERalpha complex, or in the development of tamoxifen-stimulated resistant tumor growth...
Analyses of the tumour suppressor ING1 expression and gene mutation in human basal cell carcinomaBin Chen
Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, P R China
Int J Oncol 22:927-31. 2003..Our data indicate that overexpression and mutation of the ING1 gene are infrequent in human basal cell carcinoma...
Elevated tumor necrosis factor-alpha suppresses TAZ expression and impairs osteogenic potential of Flk-1+ mesenchymal stem cells in patients with multiple myelomaBingzong Li
Institute of Basic Medical Sciences and School of Basic Medicine, Center of Excellence in Tissue Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P R China
Stem Cells Dev 16:921-30. 2007..The repressed osteogenesis and TAZ expression were both partially restored by neutralization of TNF-alpha. Thus, the decreased osteogenic potential of MSCs of myeloma patients was in part due to TNF-alpha suppressed TAZ expression...
SP1 regulates a human SNAP-25 gene expressionFang Cai
Department of Psychiatry, Brain Research Center, The University of British Columbia, Vancouver, British Columbia, Canada
J Neurochem 105:512-23. 2008..These results suggest that SP1 plays an important role in regulation of the human SNAP-25 gene expression...
The expression of cyclins in neurons of rats after focal cerebral ischemiaBin Chen
Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
J Huazhong Univ Sci Technolog Med Sci 28:60-4. 2008..05). It was concluded that there was a differential sensitivity among neurons from different brain regions to ischemic injury. But all of them re-enter into cell cycle after MCAO...
Transcriptional regulation of the human PNRC promoter by NFY in HepG2 cellsYan Zhang
Department of Biochemistry and Molecular Biology, Third Military Medical University, Chongqing 400038, China
J Biochem 143:675-83. 2008..These results indicate that the transcription factor NFY specifically binds to promoter region of PNRC and negatively regulates the transcription of the human PNRC gene...
Fast skeletal muscle troponin I is a co-activator of estrogen receptor-related receptor alphaYuping Li
Department of Biochemistry and Molecular Biology, Third Military Medical University, No 30 Gaotanyan Street, Chongqing 400038, China
Biochem Biophys Res Commun 369:1034-40. 2008..Combining mutagenesis and yeast two-hybrid assays, we mapped the ERRalpha-interacting domain on TNNI2 to a region encompassing amino acids 1-128. These findings reveal a new function for TNNI2 as a co-activator of ERRalpha...
p53-related apoptosis resistance and tumor suppression activity in UVB-induced premature senescent human skin fibroblastsWenqi Chen
Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, PR China
Int J Mol Med 21:645-53. 2008..Collectively, our data suggest that UVB-induced SIPS plays an important role in p53-related apoptosis resistance and tumor suppression activity...
The determination of projection neuron identity in the developing cerebral cortexDino P Leone
Department of Biology, Stanford University, Stanford, CA 94305, USA
Curr Opin Neurobiol 18:28-35. 2008..The molecular mechanisms by which Satb2 regulates gene expression involves long-term epigenetic changes in chromatin configuration, which may enable cell fate decisions to be maintained during development...
The Fezf2-Ctip2 genetic pathway regulates the fate choice of subcortical projection neurons in the developing cerebral cortexBin Chen
Department of Biological Sciences, Stanford University, Stanford, CA 94305, USA
Proc Natl Acad Sci U S A 105:11382-7. 2008....
Identification and characterization of PNRC splicing variantsYuanzhong Wang
Department of Biochemistry and Molecular Biology, Third Military Medical University, Chonqing, 400038, PR China
Gene 423:116-24. 2008..Our results suggest that PNRC exists as functionally distinct isoforms and alternative splicing serves as a regulatory mechanism of PNRC coactivator activity...
HTRA1 variant increases risk to neovascular age-related macular degeneration in Chinese populationFang Lu
Human Molecular Biology and Genetics, Sichuan Academy of Medical Sciences and Sichuan Provincial People s Hospital, Sichuan 610072, China
Vision Res 47:3120-3. 2007..00x10(-12)). Unlike in the Caucasian population, the risk allele of rs11200638 was not associated with drusen in our Chinese population. These findings confirm the association of HTRA1 with wet AMD...
Molecular cloning and expression analysis of a monosaccharide transporter gene OsMST4 from rice (Oryza sativa L.)Yongqin Wang
State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Datun Road, Beijing 100101, China
Plant Mol Biol 65:439-51. 2007..In addition, the cell type-specific expression patterns of OsMST4 in other sink and source tissues were also investigated, and its corresponding physiological roles were discussed...
Thermal and catalyzed [3,3]-phosphorimidate rearrangementsBin Chen
Departments of Chemistry and Medicinal Chemistry, University of Michigan, Ann Arbor, MI 48109, USA
J Am Chem Soc 127:6712-8. 2005....
Isolation and characterization of novel cyclotides from Viola hederaceae: solution structure and anti-HIV activity of vhl-1, a leaf-specific expressed cyclotideBin Chen
Institute for Molecular Bioscience, University of Queensland, Brisbane, QLD 4072, Australia
J Biol Chem 280:22395-405. 2005..Met(7) was found to be oxidized in the native form, consistent with the fact that its side chain protrudes into the solvent, occupying 7.5% of the molecular surface. vhl-1 shows anti-HIV activity with an EC(50) value of 0.87 microm...
[The research on the karyotypes of six species in the genus Eremias from China]Xing Dai
College of Bioscience and Biotechnology, Yangzhou University, Yangzhou 225 009, China
Yi Chuan 26:669-75. 2004..vermiculata is more advanced. Making specialties of E. vermiculata will help in building the phylogenic tree of Eremias. In both male and female of the species studied, the heteromorphic sex-chromosomes were not found...
A novel crosstalk mechanism between nuclear receptor-mediated and growth factor/Ras-mediated pathways through PNRC-Grb2 interactionDujin Zhou
Department of Surgical Research, Beckman Research Institute of the City of Hope, Duarte, CA 91010, USA
Oncogene 23:5394-404. 2004..This is a newly identified crosstalk mechanism for modulating these two important types of regulatory pathways...
Cycloviolacin H4, a hydrophobic cyclotide from Viola hederaceaeBin Chen
Institute for Molecular Bioscience, Australian Research Council Special Research Centre for Functional and Applied Genomics, University of Queensland, Brisbane, QLD 4072, Australia
J Nat Prod 69:23-8. 2006..This work has thus provided insight into the factors that modulate the cytotoxic properties of cyclotides...
[Special space food: microecological health food]Xi-cheng Zhou
Institute of Space Medico-Engineering, Beijing, China
Space Med Med Eng (Beijing) 16:562-5. 2003..This paper described the changes in astronauts' intestinal microflora and its adverse effects on human health, as well as the application of microecological health food in the area of manned spaceflight...
Stable transfection of an estrogen receptor beta cDNA isoform into MDA-MB-231 breast cancer cellsDebra A Tonetti
Department of Biopharmaceutical Sciences, College of Pharmacy M C 865, University of Illinois at Chicago, 833 S Wood Street, Chicago, IL 60612, USA
J Steroid Biochem Mol Biol 87:47-55. 2003..In summary, the availability of both ERalpha and ERbeta stable breast cancer cell lines now allows us to compare and contrast the long-term consequences of individual signal transduction pathways...
Purification process for vertically aligned carbon nanofibersCattien V Nguyen
NASA Ames Research Center, Moffett Field, California, USA
J Nanosci Nanotechnol 3:121-5. 2003..Electron microscopy images and Raman spectroscopy data indicate that the purification process does not damage the graphitic structure of the nanotubes...
Functional analysis on the 5'-flanking region of human FXR gene in HepG2 cellsGuiyu Lou
Department of Biochemistry and Molecular Biology, Third Military Medical University, Chongqing 400038, China
Gene 396:358-68. 2007....
Regulation of CXCR4 expression in human mesenchymal stem cells by cytokine treatment: role in homing efficiency in NOD/SCID miceMingxia Shi
Institute of Basic Medical Sciences and School of Basic Medicine, Center of Excellence in Tissue Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005, China
Haematologica 92:897-904. 2007..Homing of MSC to bone marrow (BM) post-transplantation can occur, but does so with only poor efficiency. This study was designed to evaluate the role of the SDF-1/CXCR4 axis in the homing of Flk1+ MSC derived from human fetal BM...
Nitric oxide synthase gene expression in injured spinal cord tissueChenglong Liu
Department of Orthopedics, Zhujiang Hospital, The First Military Medical University, Guangzhou 510282, China
Chin Med J (Engl) 115:740-2. 2002..043 +/- 0.049). CONCLUSION: Injury to the spinal cord leads to early up-regulation of cNOS and late up-regulation of iNOS. Different NOS isozymes may play different roles in secondary spinal cord injury...
