Farid F Chehab

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Duplication of C7orf58, WNT16 and FAM3C in an obese female with a t(7;22)(q32.1;q11.2) chromosomal translocation and clinical features resembling Coffin-Siris Syndrome
    Jun Zhu
    Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 7:e52353. 2012
  2. pmc Homozygous deletion of six olfactory receptor genes in a subset of individuals with Beta-thalassemia
    Jessica Van Ziffle
    Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 6:e17327. 2011
  3. pmc Obesity and lipodystrophy--where do the circles intersect?
    Farid F Chehab
    University of California, San Francisco, Department of Laboratory Medicine, 185 Berry Street, Suite 290, San Francisco, California 94107 0134, USA
    Endocrinology 149:925-34. 2008
  4. ncbi request reprint The use of animal models to dissect the biology of leptin
    Farid F Chehab
    Department of Laboratory Medicine, University of California, San Francisco, California 94143 0134, USA
    Recent Prog Horm Res 59:245-66. 2004
  5. doi request reprint Overexpression of the transcription factor Foxo4 is associated with rapid glucose clearance
    Biao Wang
    Department of Laboratory Medicine, University of California, San Francisco, CA 94107, USA
    Mol Cell Endocrinol 307:217-23. 2009
  6. pmc Effects of FoxO4 overexpression on cholesterol biosynthesis, triacylglycerol accumulation, and glucose uptake
    Jun Zhu
    Department of Laboratory Medicine, University of California, San Francisco, CA, USA
    J Lipid Res 51:1312-24. 2010
  7. pmc Deletion of the serotonin 2c receptor from transgenic mice overexpressing leptin does not affect their lipodystrophy but exacerbates their diet-induced obesity
    Biao Wang
    Department of Laboratory Medicine, University of California, San Francisco, CA 94143 1034, USA
    Biochem Biophys Res Commun 351:418-23. 2006
  8. ncbi request reprint Overexpression of leptin in transgenic mice leads to decreased basal lipolysis, PKA activity, and perilipin levels
    Yaohuang Ke
    Department of Laboratory Medicine, 505 Parnassus Avenue, University of California, San Francisco, CA 94143 0134, USA
    Biochem Biophys Res Commun 312:1165-70. 2003
  9. ncbi request reprint Mosaicism for a full mutation, premutation, and deletion of the CGG repeats results in 22% FMRP and elevated FMR1 mRNA levels in a high-functioning fragile X male
    Xiao Dong Han
    Department of Laboratory Medicine, University of California San Francisco, 185 Berry Street, San Francisco, CA 94107, USA
    Am J Med Genet A 140:1463-71. 2006

Research Grants

  1. LEPTIN AND INITIATION OF REPRODUCTIVE FUNCTION
    Farid Chehab; Fiscal Year: 1999
  2. LEPTIN AND INITIATION OF REPRODUCTIVE FUNCTION
    Farid Chehab; Fiscal Year: 2000
  3. LEPTIN AND INITIATION OF REPRODUCTIVE FUNCTION
    Farid Chehab; Fiscal Year: 2001

Collaborators

  • Jun Zhu
  • Wen Jun Shen
  • Enrique Saez
  • Biao Wang
  • Yaohuang Ke
  • Jessica Van Ziffle
  • Xiao Dong Han
  • Wendy Yang
  • Eric F Chehab
  • Khalid Mounzih
  • Judith L Phalin
  • Berkley R Powell
  • Fredric B Kraemer
  • Jun Qiu
  • Scott Ogus

Detail Information

Publications9

  1. pmc Duplication of C7orf58, WNT16 and FAM3C in an obese female with a t(7;22)(q32.1;q11.2) chromosomal translocation and clinical features resembling Coffin-Siris Syndrome
    Jun Zhu
    Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 7:e52353. 2012
    ....
  2. pmc Homozygous deletion of six olfactory receptor genes in a subset of individuals with Beta-thalassemia
    Jessica Van Ziffle
    Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 6:e17327. 2011
    ....
  3. pmc Obesity and lipodystrophy--where do the circles intersect?
    Farid F Chehab
    University of California, San Francisco, Department of Laboratory Medicine, 185 Berry Street, Suite 290, San Francisco, California 94107 0134, USA
    Endocrinology 149:925-34. 2008
    ..The intersection of obesity and lipodystrophy results in insulin resistance, which may be unlocked by elucidating the roles of these factors in pathways that control insulin sensitivity and glucose uptake...
  4. ncbi request reprint The use of animal models to dissect the biology of leptin
    Farid F Chehab
    Department of Laboratory Medicine, University of California, San Francisco, California 94143 0134, USA
    Recent Prog Horm Res 59:245-66. 2004
    ....
  5. doi request reprint Overexpression of the transcription factor Foxo4 is associated with rapid glucose clearance
    Biao Wang
    Department of Laboratory Medicine, University of California, San Francisco, CA 94107, USA
    Mol Cell Endocrinol 307:217-23. 2009
    ..These studies shed new light on mechanisms by which leptin treatment improves glucose disposal...
  6. pmc Effects of FoxO4 overexpression on cholesterol biosynthesis, triacylglycerol accumulation, and glucose uptake
    Jun Zhu
    Department of Laboratory Medicine, University of California, San Francisco, CA, USA
    J Lipid Res 51:1312-24. 2010
    ..Together, these studies suggest that FoxO4 acts on CYP51 to regulate the late steps of cholesterol biosynthesis...
  7. pmc Deletion of the serotonin 2c receptor from transgenic mice overexpressing leptin does not affect their lipodystrophy but exacerbates their diet-induced obesity
    Biao Wang
    Department of Laboratory Medicine, University of California, San Francisco, CA 94143 1034, USA
    Biochem Biophys Res Commun 351:418-23. 2006
    ..Thus, on a chow diet, leptin action is independent of 5HT2c receptors whereas on a high fat diet 5HT2c receptors are required for the attenuation of obesity...
  8. ncbi request reprint Overexpression of leptin in transgenic mice leads to decreased basal lipolysis, PKA activity, and perilipin levels
    Yaohuang Ke
    Department of Laboratory Medicine, 505 Parnassus Avenue, University of California, San Francisco, CA 94143 0134, USA
    Biochem Biophys Res Commun 312:1165-70. 2003
    ....
  9. ncbi request reprint Mosaicism for a full mutation, premutation, and deletion of the CGG repeats results in 22% FMRP and elevated FMR1 mRNA levels in a high-functioning fragile X male
    Xiao Dong Han
    Department of Laboratory Medicine, University of California San Francisco, 185 Berry Street, San Francisco, CA 94107, USA
    Am J Med Genet A 140:1463-71. 2006
    ....

Research Grants4

  1. LEPTIN AND INITIATION OF REPRODUCTIVE FUNCTION
    Farid Chehab; Fiscal Year: 1999
    ..This animal model for lepltin-induced puberty will allow us to correlate various levels of leptin in the circulation with reproductive indexes at reproductive maturation. ..
  2. LEPTIN AND INITIATION OF REPRODUCTIVE FUNCTION
    Farid Chehab; Fiscal Year: 2000
    ..This animal model for lepltin-induced puberty will allow us to correlate various levels of leptin in the circulation with reproductive indexes at reproductive maturation. ..
  3. LEPTIN AND INITIATION OF REPRODUCTIVE FUNCTION
    Farid Chehab; Fiscal Year: 2001
    ..This animal model for lepltin-induced puberty will allow us to correlate various levels of leptin in the circulation with reproductive indexes at reproductive maturation. ..