Ajay Chawla

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Macrophage-mediated inflammation in metabolic disease
    Ajay Chawla
    Cardiovascular Research Institute, University of California San Francisco, California 94158 9001, USA
    Nat Rev Immunol 11:738-49. 2011
  2. pmc The immune system as a sensor of the metabolic state
    Justin I Odegaard
    Cardiovascular Research Institute, University of California San Francisco, CA 94158 9001, USA
    Immunity 38:644-54. 2013
  3. pmc Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis
    Justin I Odegaard
    Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94158 9001, USA
    Science 339:172-7. 2013

Detail Information

Publications3

  1. pmc Macrophage-mediated inflammation in metabolic disease
    Ajay Chawla
    Cardiovascular Research Institute, University of California San Francisco, California 94158 9001, USA
    Nat Rev Immunol 11:738-49. 2011
    ..In particular, we focus our discussion on the pathogenic and protective functions of classically and alternatively activated macrophages, respectively, in experimental models of obesity and metabolic disease...
  2. pmc The immune system as a sensor of the metabolic state
    Justin I Odegaard
    Cardiovascular Research Institute, University of California San Francisco, CA 94158 9001, USA
    Immunity 38:644-54. 2013
    ..Such an integrated perspective both advances our understanding of basic physiology and highlights potential opportunities for therapeutic intervention in metabolic dysfunction...
  3. pmc Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis
    Justin I Odegaard
    Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94158 9001, USA
    Science 339:172-7. 2013
    ..An appreciation of the adaptive context in which these responses arose is useful for understanding their pathogenic actions in disease...

Research Grants12

  1. Role of Cytokine Signaling Pathways and Macrophages in Type 2 Diabetes Mellitus
    Ajay Chawla; Fiscal Year: 2010
    ..Thus, our studies are aimed at identifying new therapeutic targets that can improve the action of insulin, and limit or delay the onset of type 2 diabetes mellitus. ..
  2. Nuclear receptor mechanisms controlling macrophage function in health and disease
    Ajay Chawla; Fiscal Year: 2010
    ..Insights from these studies should lead to development of new therapeutics to treat chronic inflammatory and degenerative diseases, and improve modalities for tissue regeneration. ..
  3. Role of Cytokine Signaling Pathways and Macrophages in Type 2 Diabetes Mellitus
    Ajay Chawla; Fiscal Year: 2007
    ..Thus, our studies are aimed at identifying new therapeutic targets that can improve the action of insulin, and limit or delay the onset of type 2 diabetes mellitus. ..
  4. Transcriptional Control of Macrophage in Atherogenesis
    Ajay Chawla; Fiscal Year: 2007
    ..abstract_text> ..
  5. Transcriptional Control of Macrophage in Atherogenesis
    Ajay Chawla; Fiscal Year: 2010
    ..Insights from these studies should identify new therapeutic targets for intervening in atherosclerosis in which monocytes and macrophages play a key pathogenic role. ..