Susana Chavez-Bueno

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. pmc Inducible clindamycin resistance and molecular epidemiologic trends of pediatric community-acquired methicillin-resistant Staphylococcus aureus in Dallas, Texas
    Susana Chavez-Bueno
    University of Texas Southwestern Medical Center of Dallas, and Children s Medical Center of Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390 9063, USA
    Antimicrob Agents Chemother 49:2283-8. 2005
  2. pmc Respiratory syncytial virus-induced acute and chronic airway disease is independent of genetic background: an experimental murine model
    Susana Chavez-Bueno
    Division of Pediatric Infectious Diseases, Department of Pediatrics, The University of Texas Southwestern Medical Center, Children s Medical Center, Dallas, Texas, USA
    Virol J 2:46. 2005
  3. ncbi request reprint Bacterial meningitis in children
    Susana Chavez-Bueno
    Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, TX 75390 9063, USA
    Pediatr Clin North Am 52:795-810, vii. 2005
  4. pmc Anti-respiratory syncytial virus (RSV) neutralizing antibody decreases lung inflammation, airway obstruction, and airway hyperresponsiveness in a murine RSV model
    Asuncion Mejias
    Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center at Dallas and Children s Medical Center of Dallas, Dallas, Texas 75390 9063, USA
    Antimicrob Agents Chemother 48:1811-22. 2004
  5. pmc Impact of cethromycin (ABT-773) therapy on microbiological, histologic, immunologic, and respiratory indices in a murine model of Mycoplasma pneumoniae lower respiratory infection
    Ana Maria Rios
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9063, USA
    Antimicrob Agents Chemother 48:2897-904. 2004
  6. pmc Evaluation of LBM415 (NVP PDF-713), a novel peptide deformylase inhibitor, for treatment of experimental Mycoplasma pneumoniae pneumonia
    Monica Fonseca-Aten
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, 75390 9063, USA
    Antimicrob Agents Chemother 49:4128-36. 2005
  7. ncbi request reprint Mycoplasma pneumoniae induces host-dependent pulmonary inflammation and airway obstruction in mice
    Monica Fonseca-Aten
    Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9063, USA
    Am J Respir Cell Mol Biol 32:201-10. 2005
  8. pmc Comparative effects of two neutralizing anti-respiratory syncytial virus (RSV) monoclonal antibodies in the RSV murine model: time versus potency
    Asuncion Mejias
    Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390 906, USA
    Antimicrob Agents Chemother 49:4700-7. 2005
  9. pmc Microbiologic and immunologic evaluation of a single high dose of azithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia
    Ana Maria Rios
    Department of Pediatrics and Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9063, USA
    Antimicrob Agents Chemother 49:3970-3. 2005
  10. pmc Antimicrobial and immunologic activities of clarithromycin in a murine model of Mycoplasma pneumoniae-induced pneumonia
    Robert D Hardy
    Departments of Pediatrics Internal Medicine, Division of Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, USA
    Antimicrob Agents Chemother 47:1614-20. 2003

Collaborators

Detail Information

Publications22

  1. pmc Inducible clindamycin resistance and molecular epidemiologic trends of pediatric community-acquired methicillin-resistant Staphylococcus aureus in Dallas, Texas
    Susana Chavez-Bueno
    University of Texas Southwestern Medical Center of Dallas, and Children s Medical Center of Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390 9063, USA
    Antimicrob Agents Chemother 49:2283-8. 2005
    ..001). The phenotype of strains was associated with their sequence type. Our results demonstrate a clonal shift in CA-MRSA in Dallas children from 1999 to 2002...
  2. pmc Respiratory syncytial virus-induced acute and chronic airway disease is independent of genetic background: an experimental murine model
    Susana Chavez-Bueno
    Division of Pediatric Infectious Diseases, Department of Pediatrics, The University of Texas Southwestern Medical Center, Children s Medical Center, Dallas, Texas, USA
    Virol J 2:46. 2005
    ..Lung inflammation was evaluated with a histopathologic score (HPS), and AO and AHR were determined by plethysmography...
  3. ncbi request reprint Bacterial meningitis in children
    Susana Chavez-Bueno
    Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, TX 75390 9063, USA
    Pediatr Clin North Am 52:795-810, vii. 2005
    ..Better understanding of pathophysiologic mechanisms likely would result in more effective therapies in the future...
  4. pmc Anti-respiratory syncytial virus (RSV) neutralizing antibody decreases lung inflammation, airway obstruction, and airway hyperresponsiveness in a murine RSV model
    Asuncion Mejias
    Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center at Dallas and Children s Medical Center of Dallas, Dallas, Texas 75390 9063, USA
    Antimicrob Agents Chemother 48:1811-22. 2004
    ..Studies to determine whether strategies aimed at preventing or reducing RSV replication could decrease the long-term morbidity associated with RSV infection in children should be considered...
  5. pmc Impact of cethromycin (ABT-773) therapy on microbiological, histologic, immunologic, and respiratory indices in a murine model of Mycoplasma pneumoniae lower respiratory infection
    Ana Maria Rios
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9063, USA
    Antimicrob Agents Chemother 48:2897-904. 2004
    ..pneumoniae culture titers in BAL samples, cytokine and chemokine concentrations in BAL samples, histologic inflammation in the lungs, and disease severity as defined by AO and AHR...
  6. pmc Evaluation of LBM415 (NVP PDF-713), a novel peptide deformylase inhibitor, for treatment of experimental Mycoplasma pneumoniae pneumonia
    Monica Fonseca-Aten
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, 75390 9063, USA
    Antimicrob Agents Chemother 49:4128-36. 2005
    ..LBM415 therapy had beneficial microbiologic, histologic, respiratory, and immunologic effects on acute murine M. pneumoniae pneumonia...
  7. ncbi request reprint Mycoplasma pneumoniae induces host-dependent pulmonary inflammation and airway obstruction in mice
    Monica Fonseca-Aten
    Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9063, USA
    Am J Respir Cell Mol Biol 32:201-10. 2005
    ..The mice in this study exhibited host-dependent infection-related AO and AHR associated with chemokine and T-helper type (Th)1 pulmonary host response and not Th2 response after M. pneumoniae infection...
  8. pmc Comparative effects of two neutralizing anti-respiratory syncytial virus (RSV) monoclonal antibodies in the RSV murine model: time versus potency
    Asuncion Mejias
    Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390 906, USA
    Antimicrob Agents Chemother 49:4700-7. 2005
    ..MEDI-524 was superior to palivizumab on several outcome variables of RSV disease assessed in the mouse model: viral replication, inflammatory and clinical markers of acute disease severity, and long-term pulmonary abnormalities...
  9. pmc Microbiologic and immunologic evaluation of a single high dose of azithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia
    Ana Maria Rios
    Department of Pediatrics and Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9063, USA
    Antimicrob Agents Chemother 49:3970-3. 2005
    ..Although both azithromycin regimens significantly reduced quantitative cultures, lung histopathology, and pulmonary cytokines and chemokines, there were no significant differences between the two regimens...
  10. pmc Antimicrobial and immunologic activities of clarithromycin in a murine model of Mycoplasma pneumoniae-induced pneumonia
    Robert D Hardy
    Departments of Pediatrics Internal Medicine, Division of Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, USA
    Antimicrob Agents Chemother 47:1614-20. 2003
    ..pneumoniae; this was not observed in the mice inoculated with UV-killed M. pneumoniae...
  11. ncbi request reprint Respiratory syncytial virus induces pneumonia, cytokine response, airway obstruction, and chronic inflammatory infiltrates associated with long-term airway hyperresponsiveness in mice
    Hasan S Jafri
    Department of Pediatrics, Division of Infectious Diseases, The University of Texas Southwestern Medical Center at Dallas, Texas, USA
    J Infect Dis 189:1856-65. 2004
    ..pneumonia and airway obstruction [AO]) and long-term complications (e.g., airway hyperresponsiveness [AHR]). We present a comprehensive evaluation of the acute and chronic phases of RSV respiratory tract infection, using a mouse model...
  12. pmc Motavizumab, a neutralizing anti-Respiratory Syncytial Virus (Rsv) monoclonal antibody significantly modifies the local and systemic cytokine responses induced by Rsv in the mouse model
    Asuncion Mejias
    Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center at Dallas, Texas, USA
    Virol J 4:109. 2007
    ....
  13. doi request reprint Respiratory syncytial virus persistence: evidence in the mouse model
    Asuncion Mejias
    Department of Pediatrics, Division of Pediatric Infectious Diseases, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9063, USA
    Pediatr Infect Dis J 27:S60-2. 2008
    ..Future studies are needed to define the significance of persistent RSV RNA in the mouse model, and its potential role in the pathogenesis of RSV-induced persistent wheezing in children...
  14. ncbi request reprint Respiratory syncytial virus: old challenges and new approaches
    Susana Chavez-Bueno
    Pediatrics Department, Division of Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, TX 75390 9063, USA
    Pediatr Ann 34:62-8. 2005
    ....
  15. ncbi request reprint Respiratory syncytial virus infections: old challenges and new opportunities
    Asuncion Mejias
    Division of Pediatric Infectious Diseases, The University of Texas Southwestern Medical Center and Children s Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Pediatr Infect Dis J 24:S189-96, discussion S196-7. 2005
    ..RSV also causes repeated infections including severe lower respiratory tract disease, which may occur at any age, especially among the elderly or those with compromised cardiac, pulmonary, or immune systems...
  16. ncbi request reprint Effect of clarithromycin on cytokines and chemokines in children with an acute exacerbation of recurrent wheezing: a double-blind, randomized, placebo-controlled trial
    Monica Fonseca-Aten
    Departments of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9063, USA
    Ann Allergy Asthma Immunol 97:457-63. 2006
    ..Clarithromycin is postulated to possess immunomodulatory properties in addition to its antimicrobial activity...
  17. ncbi request reprint Treatment of experimental chronic pulmonary mycoplasmosis
    Monica Fonseca-Aten
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Int J Antimicrob Agents 28:253-8. 2006
    ..Therapy longer than 10 days may be necessary to improve pulmonary function...
  18. ncbi request reprint Intravenous palivizumab and ribavirin combination for respiratory syncytial virus disease in high-risk pediatric patients
    Susana Chavez-Bueno
    Department of Pediatrics, Division of Infectious Diseases, The University of Texas Southwestern Medical Center at Dallas, TX 75390 9063, USA
    Pediatr Infect Dis J 26:1089-93. 2007
    ..Palivizumab is approved for prevention of RSV disease, and ribavirin is approved for treatment of RSV infections but its efficacy in high-risk patients has not been conclusively established...
  19. ncbi request reprint Human metapneumovirus: a not so new virus
    Asuncion Mejias
    Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Pediatr Infect Dis J 23:1-7; quiz 8-10. 2004
  20. ncbi request reprint Respiratory syncytial virus pneumonia: mechanisms of inflammation and prolonged airway hyperresponsiveness
    Asuncion Mejias
    Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center and Children s Medical Center, Dallas, Texas 75390 9063, USA
    Curr Opin Infect Dis 18:199-204. 2005
    ..This review highlights new findings reported in the English-language medical literature from January 2004 to January 2005...
  21. doi request reprint Antibacterial agents in pediatrics
    Susana Chavez-Bueno
    Department of Pediatrics, Section of Pediatric Infectious Diseases, University of Oklahoma Health Sciences Center, 940 NE 13th Street, Room 2B 2311, Oklahoma City, OK 73104, USA
    Infect Dis Clin North Am 23:865-80, viii. 2009
    ..This article describes the pharmacologic characteristics and therapeutic use of the most commonly prescribed antibacterials for pediatric patients. Newer agents currently under clinical investigation are discussed as well...
  22. doi request reprint Pediatric vaccines on the horizon
    Susana Chavez-Bueno
    Section of Infectious Diseases, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Am J Med Sci 340:226-31. 2010
    ..Financial barriers and other obstacles to adequate vaccine access need to be eliminated to assure coverage for all children and adolescents...