Research Topics
Species | Susana Chavez-BuenoSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Detail Information
Publications
Inducible clindamycin resistance and molecular epidemiologic trends of pediatric community-acquired methicillin-resistant Staphylococcus aureus in Dallas, TexasSusana Chavez-Bueno
University of Texas Southwestern Medical Center of Dallas, and Children s Medical Center of Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390 9063, USA
Antimicrob Agents Chemother 49:2283-8. 2005..001). The phenotype of strains was associated with their sequence type. Our results demonstrate a clonal shift in CA-MRSA in Dallas children from 1999 to 2002...- Respiratory syncytial virus-induced acute and chronic airway disease is independent of genetic background: an experimental murine modelSusana Chavez-Bueno
Division of Pediatric Infectious Diseases, Department of Pediatrics, The University of Texas Southwestern Medical Center, Children s Medical Center, Dallas, Texas, USA
Virol J 2:46. 2005..Lung inflammation was evaluated with a histopathologic score (HPS), and AO and AHR were determined by plethysmography... 
Bacterial meningitis in childrenSusana Chavez-Bueno
Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, TX 75390 9063, USA
Pediatr Clin North Am 52:795-810, vii. 2005..Better understanding of pathophysiologic mechanisms likely would result in more effective therapies in the future...- Anti-respiratory syncytial virus (RSV) neutralizing antibody decreases lung inflammation, airway obstruction, and airway hyperresponsiveness in a murine RSV modelAsuncion Mejias
Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center at Dallas and Children s Medical Center of Dallas, Dallas, Texas 75390 9063, USA
Antimicrob Agents Chemother 48:1811-22. 2004..Studies to determine whether strategies aimed at preventing or reducing RSV replication could decrease the long-term morbidity associated with RSV infection in children should be considered... - Evaluation of LBM415 (NVP PDF-713), a novel peptide deformylase inhibitor, for treatment of experimental Mycoplasma pneumoniae pneumoniaMonica Fonseca-Aten
Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, 75390 9063, USA
Antimicrob Agents Chemother 49:4128-36. 2005..LBM415 therapy had beneficial microbiologic, histologic, respiratory, and immunologic effects on acute murine M. pneumoniae pneumonia... - Impact of cethromycin (ABT-773) therapy on microbiological, histologic, immunologic, and respiratory indices in a murine model of Mycoplasma pneumoniae lower respiratory infectionAna Maria Rios
Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9063, USA
Antimicrob Agents Chemother 48:2897-904. 2004..pneumoniae culture titers in BAL samples, cytokine and chemokine concentrations in BAL samples, histologic inflammation in the lungs, and disease severity as defined by AO and AHR... - Microbiologic and immunologic evaluation of a single high dose of azithromycin for treatment of experimental Mycoplasma pneumoniae pneumoniaAna Maria Rios
Department of Pediatrics and Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9063, USA
Antimicrob Agents Chemother 49:3970-3. 2005..Although both azithromycin regimens significantly reduced quantitative cultures, lung histopathology, and pulmonary cytokines and chemokines, there were no significant differences between the two regimens... - Mycoplasma pneumoniae induces host-dependent pulmonary inflammation and airway obstruction in miceMonica Fonseca-Aten
Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9063, USA
Am J Respir Cell Mol Biol 32:201-10. 2005..The mice in this study exhibited host-dependent infection-related AO and AHR associated with chemokine and T-helper type (Th)1 pulmonary host response and not Th2 response after M. pneumoniae infection... - Comparative effects of two neutralizing anti-respiratory syncytial virus (RSV) monoclonal antibodies in the RSV murine model: time versus potencyAsuncion Mejias
Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390 906, USA
Antimicrob Agents Chemother 49:4700-7. 2005..MEDI-524 was superior to palivizumab on several outcome variables of RSV disease assessed in the mouse model: viral replication, inflammatory and clinical markers of acute disease severity, and long-term pulmonary abnormalities... - Antimicrobial and immunologic activities of clarithromycin in a murine model of Mycoplasma pneumoniae-induced pneumoniaRobert D Hardy
Departments of Pediatrics Internal Medicine, Division of Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, USA
Antimicrob Agents Chemother 47:1614-20. 2003..pneumoniae; this was not observed in the mice inoculated with UV-killed M. pneumoniae... - Respiratory syncytial virus induces pneumonia, cytokine response, airway obstruction, and chronic inflammatory infiltrates associated with long-term airway hyperresponsiveness in miceHasan S Jafri
Department of Pediatrics, Division of Infectious Diseases, The University of Texas Southwestern Medical Center at Dallas, Texas, USA
J Infect Dis 189:1856-65. 2004..pneumonia and airway obstruction [AO]) and long-term complications (e.g., airway hyperresponsiveness [AHR]). We present a comprehensive evaluation of the acute and chronic phases of RSV respiratory tract infection, using a mouse model... - Motavizumab, a neutralizing anti-Respiratory Syncytial Virus (Rsv) monoclonal antibody significantly modifies the local and systemic cytokine responses induced by Rsv in the mouse modelAsuncion Mejias
Department of Pediatrics, Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center at Dallas, Texas, USA
Virol J 4:109. 2007.... - Respiratory syncytial virus: old challenges and new approachesSusana Chavez-Bueno
Pediatrics Department, Division of Infectious Diseases, University of Texas Southwestern Medical Center, Dallas, TX 75390 9063, USA
Pediatr Ann 34:62-8. 2005.... - Respiratory syncytial virus infections: old challenges and new opportunitiesAsuncion Mejias
Division of Pediatric Infectious Diseases, The University of Texas Southwestern Medical Center and Children s Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
Pediatr Infect Dis J 24:S189-96, discussion S196-7. 2005..RSV also causes repeated infections including severe lower respiratory tract disease, which may occur at any age, especially among the elderly or those with compromised cardiac, pulmonary, or immune systems... 
Respiratory syncytial virus persistence: evidence in the mouse modelAsuncion Mejias
Department of Pediatrics, Division of Pediatric Infectious Diseases, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9063, USA
Pediatr Infect Dis J 27:S60-2. 2008..Future studies are needed to define the significance of persistent RSV RNA in the mouse model, and its potential role in the pathogenesis of RSV-induced persistent wheezing in children...- Effect of clarithromycin on cytokines and chemokines in children with an acute exacerbation of recurrent wheezing: a double-blind, randomized, placebo-controlled trialMonica Fonseca-Aten
Departments of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9063, USA
Ann Allergy Asthma Immunol 97:457-63. 2006..CONCLUSION: Clarithromycin therapy reduces mucosal TNF-alpha, IL-1beta, and IL-10 concentrations in children with an acute exacerbation of recurrent wheezing... - Treatment of experimental chronic pulmonary mycoplasmosisMonica Fonseca-Aten
Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA
Int J Antimicrob Agents 28:253-8. 2006..Therapy longer than 10 days may be necessary to improve pulmonary function... - Human metapneumovirus: a not so new virusAsuncion Mejias
Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas, USA
Pediatr Infect Dis J 23:1-7; quiz 8-10. 2004 - Respiratory syncytial virus pneumonia: mechanisms of inflammation and prolonged airway hyperresponsivenessAsuncion Mejias
Division of Pediatric Infectious Diseases, University of Texas Southwestern Medical Center and Children s Medical Center, Dallas, Texas 75390 9063, USA
Curr Opin Infect Dis 18:199-204. 2005..This review highlights new findings reported in the English-language medical literature from January 2004 to January 2005... - Antibacterial agents in pediatricsSusana Chavez-Bueno
Department of Pediatrics, Section of Pediatric Infectious Diseases, University of Oklahoma Health Sciences Center, 940 NE 13th Street, Room 2B 2311, Oklahoma City, OK 73104, USA
Infect Dis Clin North Am 23:865-80, viii. 2009..This article describes the pharmacologic characteristics and therapeutic use of the most commonly prescribed antibacterials for pediatric patients. Newer agents currently under clinical investigation are discussed as well... - Intravenous palivizumab and ribavirin combination for respiratory syncytial virus disease in high-risk pediatric patientsSusana Chavez Bueno
Department of Pediatrics, Division of Infectious Diseases, The University of Texas Southwestern Medical Center at Dallas, TX 75390 9063, USA
Pediatr Infect Dis J 26:1089-93. 2007..Palivizumab is approved for prevention of RSV disease, and ribavirin is approved for treatment of RSV infections but its efficacy in high-risk patients has not been conclusively established... - Pediatric vaccines on the horizonSusana Chavez-Bueno
Section of Infectious Diseases, Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
Am J Med Sci 340:226-31. 2010..Financial barriers and other obstacles to adequate vaccine access need to be eliminated to assure coverage for all children and adolescents...