Research Topics
Species | M Ahmad ChaudhrySummaryAffiliation: University of Vermont Country: USA Publications
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Detail Information
Publications
Biomarkers for human radiation exposureM Ahmad Chaudhry
Department of Medical Laboratory and Radiation Sciences, College of Nursing and Health Sciences, University of Vermont, 302 Rowell Building, Burlington, VT 05405, USA
J Biomed Sci 15:557-63. 2008..Microarray based studies are identifying new radiation responsive genes that could potentially be used as biomarkers of human exposure to radiation after an accident...
Differential regulation of microRNA expression in irradiated and bystander cellsM A Chaudhry
Department of Medical Laboratory and Radiation Sciences, University of Vermont, Burlington, VT 05405, USA
Mol Biol (Mosk) 46:634-43. 2012..While the expression of miR-15a, miR-16, miR-155, and miR-21 was repressed, the miR-143 and miR-145 expression was induced in bystander cells. These results indicate the involvement of miRNA modulation in irradiated and bystander cells...
Differential DNA methylation alterations in radiation-sensitive and -resistant cellsM Ahmad Chaudhry
Department of Medical Laboratory and Radiation Sciences, University of Vermont, Burlington, Vermont 05405, USA
DNA Cell Biol 31:908-16. 2012..This study also shows that DNA methylation patterns change at different genomic regions and are dependent on time after irradiation and the genetic background of the cell...
Micro RNA responses to chronic or acute exposures to low dose ionizing radiationM Ahmad Chaudhry
Department of Medical Laboratory and Radiation Sciences, University of Vermont, 302 Rowell Building, Burlington, VT 05405, USA
Mol Biol Rep 39:7549-58. 2012..This information will contribute to understanding the risks to human health after exposure to low dose radiation...
Mitochondrial gene expression in directly irradiated and nonirradiated bystander cellsM Ahmad Chaudhry
Department of Medical Laboratory and Radiation Sciences, University of Vermont, Burlington, VT 05405, USA
Cancer Biother Radiopharm 26:657-63. 2011....
An exercise to estimate differential gene expression in human cellsM Ahmad Chaudhry
Department of Medical Laboratory and Radiation Sciences, Burlington, Vermont 05405 DNA Microarray Facility, University of Vermont, Burlington, Vermont 05405
Biochem Mol Biol Educ 34:116-20. 2006..This technique should have a wide application to investigate differential gene expression in a variety of organisms and under various experimental and treatment conditions...
Transcriptional modulation of micro-RNA in human cells differing in radiation sensitivityM Ahmad Chaudhry
Department of Medical Laboratory and Radiation Sciences, University of Vermont, Burlington, Vermont 05405, USA
Int J Radiat Biol 86:569-83. 2010..We hypothesised that ionising radiation induced stress response is controlled in part by miRNA and that a difference in tumour protein 53 (p53) status corresponds with altered expression in miRNA responses to ionising radiation...
Strategies for detecting genomic DNA methylation: a survey of US patentsM Ahmad Chaudhry
Department of Medical Laboratory and Radiation Sciences, 302 Rowell Building, University of Vermont, Burlington, VT 05405, USA
Recent Pat DNA Gene Seq 4:79-85. 2010..The disease diagnosis was the prominent application of DNA methylation detection for most of these methods. Future inventions will likely concentrate on genome-scale DNA methylation discovery...
Radiation-induced micro-RNA modulation in glioblastoma cells differing in DNA-repair pathwaysM Ahmad Chaudhry
Department of Medical Laboratory and Radiation Sciences, University of Vermont, Burlington, Vermont, USA
DNA Cell Biol 29:553-61. 2010..These results indicate the involvement of miRNAs in the differential response of glioblastoma cells to ionizing radiation treatment...
Real-time PCR analysis of micro-RNA expression in ionizing radiation-treated cellsM Ahmad Chaudhry
Department of Medical Laboratory and Radiation Sciences, University of Vermont, Burlington, VT 05405, USA
Cancer Biother Radiopharm 24:49-56. 2009..These results provide a first glimpse to indicate the involvement of miRNA in radiation-induced stress response and will lead to functional studies dissecting the molecular details of these processes...
Analysis of gene expression in normal and cancer cells exposed to gamma-radiationM Ahmad Chaudhry
Department of Medical Laboratory and Radiation Sciences, University of Vermont, 302 Rowell Building, Burlington, 05405 VT, USA
J Biomed Biotechnol 2008:541678. 2008..These results indicate cell specific modulation of gene expression and suggest the involvement of different pathways in cellular response to radiation treatment in different cells...
Bystander effect: biological endpoints and microarray analysisM Ahmad Chaudhry
Department of Medical Laboratory and Radiation Sciences, College of Nursing and Health Sciences, University of Vermont, 302 Rowell Building, Burlington, VT 05405, USA
Mutat Res 597:98-112. 2006..The induction of receptors and the cell communication processes in bystander cells receiving media from irradiated cells supports the active involvement of these processes in inducing bystander effect...
Radiation-induced gene expression profile of human cells deficient in 8-hydroxy-2'-deoxyguanine glycosylaseM Ahmad Chaudhry
Department of Medical Laboratory and Radiation Sciences, DNA Microarray Facility, University of Vermont, Burlington, VT 05405, USA
Int J Cancer 118:633-42. 2006..Microarray gene expression data were independently validated by relative quantitative RT-PCR. Surprisingly, none of the genes involved in the base excision repair of radiation-induced DNA damage showed altered expression...
Gene expression profile of human cells irradiated in G1 and G2 phases of cell cycleM Ahmad Chaudhry
Department of Microbiology and Molecular Genetics, University of Vermont, 226 Stafford Hall, Burlington 05401, USA
Cancer Lett 195:221-33. 2003..These studies have revealed cell cycle dependence on radiation-induced gene induction and have permitted the identification of previously known as well as unknown genes associated with radiation-induced altered expression...
Base excision repair by hNTH1 and hOGG1: a two edged sword in the processing of DNA damage in gamma-irradiated human cellsNing Yang
Department of Microbiology and Molecular Genetics, The Markey Center for Molecular Genetics, The University of Vermont, 95 Carrigan Drive, Stafford Hall, Burlington, VT 05405 0068, USA
DNA Repair (Amst) 5:43-51. 2006..Here, overexpression of hNTH1 and hOGG1 resulted in reduced cell killing while suppression of glycosylase expression resulted in elevated cell death...
Current approaches to micro-RNA analysis and target gene predictionTenzin W Lhakhang
Department of Medical Laboratory and Radiation Sciences, University of Vermont, 302 Rowell Building, Burlington, VT 05405, USA
J Appl Genet 53:149-58. 2012..This article will bring together the information on our current knowledge of miRNA biology, the approaches for miRNA analysis, and computational strategies to gain insight in miRNA functional roles...
Detection of genomic DNA methylation with denaturing high performance liquid chromatographyRomaica A Omaruddin
Department of Medical Laboratory and Radiation Science, University of Vermont, Burlington, Vermont 05405, USA
Hum Cell 23:41-9. 2010..In conclusion, DHPLC technology serves as a rapid screening tool to monitor the genomic DNA methylation and could be used to increase the throughput efficiency of methylation analysis...
Gene expression profiling of HeLa cells in G1 or G2 phasesM Ahmad Chaudhry
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, PA 19104, USA
Oncogene 21:1934-42. 2002..Some of these genes are candidates for transition through early G1. This gene inventory for G1 and G2 phases of cell cycle will provide the basis for understanding of cell cycle delay as a result of DNA damage...
