Research Topics
| EDWIN DUNCAN CHARLEBOISSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Effect of trimethoprim-sulphamethoxazole on the risk of malaria in HIV-infected Ugandan children living in an area of widespread antifolate resistanceAnne F Gasasira
School of Medicine, Makerere University Kampala, Uganda
Malar J 9:177. 2010..This study assessed the incidence of falciparum malaria and the prevalence of resistance-conferring Plasmodium falciparum mutations in HIV-infected children receiving daily TS and HIV-uninfected children not taking TS...- The effect of expanded antiretroviral treatment strategies on the HIV epidemic among men who have sex with men in San FranciscoEdwin D Charlebois
HIV AIDS Division, Department of Medicine, San Francisco General Hospital, California, USA
Clin Infect Dis 52:1046-9. 2011..Addition of annual HIV testing for men who have sex with men to universal treatment decreases new infections by 76%... - Short-term risk of HIV disease progression and death in Ugandan children not eligible for antiretroviral therapyEdwin D Charlebois
School of Medicine, University of California, San Francisco, CA 94105, USA
J Acquir Immune Defic Syndr 55:330-5. 2010..Increasing numbers of HIV-infected children not yet eligible for antiretroviral therapy (ART) are entering health care in Africa. We sought to characterize the risk of short-term disease progression in this population... 
Population dynamics of nasal strains of methicillin-resistant Staphylococcus aureus--and their relation to community-associated disease activityErica S Pan
Department of Medicine, Division of Infectious Diseases, University of California, San Francisco, California, USA
J Infect Dis 192:811-8. 2005....- HIV seroprevalence among homeless and marginally housed adults in San FranciscoMarjorie J Robertson
Department of Epidemiology, University of California, San Francisco, USA
Am J Public Health 94:1207-17. 2004..We report HIV seroprevalence and risk factors for urban indigent adults... - Community-adapted methicillin-resistant Staphylococcus aureus (MRSA): population dynamics of an expanding community reservoir of MRSAHeather A Carleton
Department of Medicine, Division of Infectious Diseases, University of California, San Francisco, San Francisco, California 94110, USA
J Infect Dis 190:1730-8. 2004..The longitudinal results linked the dramatic increase in MRSA infections to an expanding community reservoir of MRSA genotypes with intrinsic community survival advantage... - Hepatitis C virus infection in San Francisco's HIV-infected urban poorChristopher S Hall
Division of Infectious Diseases, San Francisco General Hospital, San Francisco, California, USA
J Gen Intern Med 19:357-65. 2004..Urban poor, nonwhite individuals are less likely to receive HCV testing and subspecialty referral than their white counterparts. Antibody-negative infection may complicate screening and diagnosis in HIV-infected persons. J.. - Reducing risky sexual behavior and substance use among currently and formerly homeless adults living with HIVMary Jane Rotheram-Borus
Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, USA
Am J Public Health 99:1100-7. 2009..We examined the efficacy of the Healthy Living Program in reducing risky sexual behavior and substance use among adults with HIV infection who were marginally housed (i.e., homeless at some point over a 37-month period)... - Inappropriate antibiotic use in soft tissue infectionsKeyianoosh Z Paydar
Division of Infectious Diseases, Department of Surgery, San Francisco General Hospital, University of California, San Francisco, CA 94110, USA
Arch Surg 141:850-4; discussion 855-6. 2006..CONCLUSIONS: Treatment of soft tissue infections after surgical drainage, even with inappropriate antibiotics, has a high cure rate. Further studies to evaluate the efficacy of treating these infections without antibiotics are needed... - HIV seroconversion among the homeless and marginally housed in San Francisco: a ten-year studyJudith A Hahn
Department of Medicine, University of California, San Francisco, CA 94143-1347, USA
J Acquir Immune Defic Syndr 37:1616-9. 2004..Policy implications are that HIV resources aimed at the more stable, older homeless population should probably focus on treatment, while prevention efforts, conversely, should probably be targeted to younger homeless persons... - Origins of community strains of methicillin-resistant Staphylococcus aureusEdwin D Charlebois
Department of Medicine, Division of Infectious Diseases, UCSF and Clinical Laboratory, San Francisco General Hospital, San Francisco, CA 94143, USA
Clin Infect Dis 39:47-54. 2004..In a nonoutbreak setting, the hospital was the main source of community MRSA; however, the presence of genetically distinct and diverse MRSA strains indicates MRSA strains now also originate from the community... - Randomized controlled trial of a cognitive-behavioral intervention for HIV-positive persons: an investigation of treatment effects on psychosocial adjustmentAdam W Carrico
Department of Psychiatry, Health Psychology Program, University of California, San Francisco, 3333 California St, Suite 465, Box 0848, San Francisco, CA 94143 0848, USA
AIDS Behav 13:555-63. 2009..More intensive mental health interventions may be necessary to improve psychosocial adjustment among HIV-positive individuals... - Effects of behavioral intervention on substance use among people living with HIV: the Healthy Living Project randomized controlled studyF Lennie Wong
University of California, Los Angeles, CA, USA
Addiction 103:1206-14. 2008..Reductions in substance use were examined in response to an intensive intervention with people living with human immunodeficiency virus (HIV) (PLH)... - Receipt of prevention services among HIV-infected men who have sex with menWayne T Steward
Center for AIDS Prevention Studies, University of California, San Francisco, 50 Beale St, Suite 1300, San Francisco, CA 94105, USA
Am J Public Health 98:1011-4. 2008..Greater efforts should be made to ensure that prevention counseling is delivered to all HIV-infected persons, especially men who have sex with men... - Affect regulation, stimulant use, and viral load among HIV-positive persons on anti-retroviral therapyAdam W Carrico
Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94143 0848, USA
Psychosom Med 69:785-92. 2007..The present study examined the associations among affect regulation, substance use, non-adherence to anti-retroviral therapy (ART), and immune status in a diverse sample of HIV-positive persons... - Project Accept (HPTN 043): a community-based intervention to reduce HIV incidence in populations at risk for HIV in sub-Saharan Africa and ThailandGertrude Khumalo-Sakutukwa
Center for AIDS Prevention Studies, University of California, San Francisco, 50 Beale Street, Suite 1300, San Francisco, CA 94105, USA
J Acquir Immune Defic Syndr 49:422-31. 2008..Changing community norms to increase awareness of HIV status and reduce HIV-related stigma has the potential to reduce the incidence of HIV-1 infection in the developing world... - A behavioral intervention reduces HIV transmission risk by promoting sustained serosorting practices among HIV-infected men who have sex with menStephen F Morin
Center for AIDS Prevention Studies, University of California, San Francisco, San Francisco, CA 94105, USA
J Acquir Immune Defic Syndr 49:544-51. 2008..To examine factors that explain the effect of a cognitive-behavioral intervention on reductions in HIV transmission risk among HIV-infected men who have sex with men (MSM)... - Polymerase chain reaction of secA1 on sputum or oral wash samples for the diagnosis of pulmonary tuberculosisJ Lucian Davis
Department of Medicine, San Francisco General Hospital and University of California, San Francisco, California 94110, USA
Clin Infect Dis 48:725-32. 2009..Few studies have assessed their performance among patients infected with HIV, and no studies have assessed their performance with oral wash specimens, which may be easier to obtain than sputum samples... - Dynamics of T cell activation accompanying CD4 recovery in antiretroviral treated HIV-infected Ugandan childrenTheodore Ruel
Department of Pediatrics, Division of Infectious Disease, University of California, San Francisco, San Francisco, CA 94143 0136, USA
Clin Immunol 131:410-4. 2009..008). Our data suggest that significant decreases in T cell activation accompany CD4 recovery in ART-treated HIV-infected African children, to levels that approach but do not reach those of uninfected children... - Patient perspectives with abbreviated versus standard pre-test HIV counseling in the prenatal setting: a randomized-controlled, non-inferiority trialDeborah Cohan
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 4:e5166. 2009..Previous studies have found increased uptake of prenatal HIV testing with abbreviated pre-test counseling, however little is known about patient decision making, testing satisfaction and knowledge in this setting... - Mycobacterium tuberculosis microbiologic and clinical treatment outcomes in a randomized trial of immediate versus CD4(+)-initiated antiretroviral therapy in HIV-infected adults with a high CD4(+) cell countGabriel Chamie
Department of Medicine, University of California, San Francisco, CA, USA
Clin Infect Dis 51:359-62. 2010..Trial registration. ClinicalTrials.gov identifier: NCT00078247 ... - Early virologic failure and the development of antiretroviral drug resistance mutations in HIV-infected Ugandan childrenTheodore D Ruel
Department of Pediatrics, School of Medicine, University of California, San Francisco, San Francisco, CA 94143 0136, USA
J Acquir Immune Defic Syndr 56:44-50. 2011..We sought to determine the prevalence of early virologic failure (EVF), to characterize the evolution of ARV-resistance mutations and to predict the impact on second-line therapy... - Psychiatric risk factors for HIV disease progression: the role of inconsistent patterns of antiretroviral therapy utilizationAdam W Carrico
Center for AIDS Prevention Studies, University of California, San Francisco, CA 94105, USA
J Acquir Immune Defic Syndr 56:146-50. 2011..In the era of antiretroviral therapy (ART), depression and substance use predict hastened HIV disease progression, but the underlying biological or behavioral mechanisms that explain these effects are not fully understood... - Correlates of suicidal ideation among HIV-positive personsAdam W Carrico
Health Psychology Program, Department of Psychiatry, University of California San Francisco, 3333 California Street, San Francisco, CA 94143, USA
AIDS 21:1199-203. 2007.... - Comparison of an interferon-gamma release assay with tuberculin skin testing in HIV-infected individualsAnnie F Luetkemeyer
HIV AIDS Division, San Francisco General Hospital, University of California at San Fracisco, San Francisco, Box 0874, Building 80, 995 Potrero Avenue, San Francisco, CA 94110, USA
Am J Respir Crit Care Med 175:737-42. 2007..Although interferon (IFN)-gamma release assays are approved for the diagnosis of latent tuberculosis infection (LTBI), limited data exist regarding their performance in HIV infection... - Increasing prevalence of methicillin-resistant Staphylococcus aureus infection in California jailsErica S Pan
Department of Pediatrics, San Francisco General Hospital, San Francisco, California 94110, USA
Clin Infect Dis 37:1384-8. 2003..One of these clonal groups is genetically indistinguishable from the strain responsible for an outbreak of MRSA in the Los Angeles County jail system in 2002... - Are untimed antiretroviral drug levels useful predictors of adherence behavior?Cheryl A Liechty
Division of Infectious Diseases, University of California San Francisco, San Francisco, CA, USA
AIDS 18:127-9. 2004..An abnormally low drug level was associated with a higher viral load. A single abnormally low untimed antiretroviral drug level can identify an individual with very low adherence at high risk of HIV disease progression and death... - Modeling the HIV protease inhibitor adherence-resistance curve by use of empirically derived estimatesDavid R Bangsberg
Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, San Francisco General Hospital AIDS Program, University of California San Francisco, 94110, USA
J Infect Dis 190:162-5. 2004..Higher levels of viral suppression at 100% adherence (a marker of greater regimen potency) progressively reduce the overall population rate of drug resistance and shift the peak resistance rate to lower levels of adherence... - Multiple validated measures of adherence indicate high levels of adherence to generic HIV antiretroviral therapy in a resource-limited settingJessica H Oyugi
Epidemiology and Prevention Interventions Center and San Francisco General Hospital AIDS Program, University of California at San Francisco, San Francisco, CA 94143, USA
J Acquir Immune Defic Syndr 36:1100-2. 2004..The relative ease of administration of the 30-day visual analog scale suggests that this may be the preferred method to assess adherence in resource-poor settings... - An epidemic of methicillin-resistant Staphylococcus aureus soft tissue infections among medically underserved patientsDavid M Young
Department of Surgery, San Francisco General Hospital, University of California, San Francisco 94110, USA
Arch Surg 139:947-51; discussion 951-3. 2004..A high prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in soft tissue infections presents a treatment challenge... - Adherence to highly active antiretroviral therapy in the homeless population in San Francisco: a prospective studyAndrew R Moss
Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94110, USA
Clin Infect Dis 39:1190-8. 2004.... - Impact of a formulary switch from ticarcillin-clavulanate to piperacillin-tazobactam on colonization with vancomycin-resistant enterococciLisa G Winston
Department of Medicine, Division of Infectious Diseases, University of California San Francisco and SF General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA
Am J Infect Control 32:462-9. 2004..The prevalence of vancomycin-resistant enterococci (VRE) is increasing, despite infection control measures. Limited data link ticarcillin-clavulanate to higher VRE prevalence... - Predicting HIV transmission risk among HIV-infected men who have sex with men: findings from the healthy living projectStephen F Morin
Center for AIDS Prevention Studies, University of California, San Francisco, CA 94105, USA
J Acquir Immune Defic Syndr 40:226-35. 2005..To examine the predictors of transmission risk among HIV-infected men who have sex with men (MSM) in 4 US cities... - Population-based community prevalence of methicillin-resistant Staphylococcus aureus in the urban poor of San FranciscoEdwin D Charlebois
Department of Medicine, Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, San Francisco General Hospital, San Francisco, CA 94110, USA
Clin Infect Dis 34:425-33. 2002..Only 2 individuals (0.24%) with MRSA had no known risk factors. A total of 22 of 23 community MRSA genotypically matched clinical MRSA isolates, with 15 of 23 isolates identical to MRSA clones endemic among hospitalized patients... - Removing barriers to knowing HIV status: same-day mobile HIV testing in ZimbabweStephen F Morin
AIDS Policy Research Center, Department of Medicine, University of California, San Francisco, San Francisco, CA 94105, USA
J Acquir Immune Defic Syndr 41:218-24. 2006.... - Potential deterrent effect of name-based HIV infection surveillanceEdwin D Charlebois
Center for AIDS Prevention Studies, AIDS Policy Research Center, AIDS Research Institute, University of California, San Francisco, CA 94105, USA
J Acquir Immune Defic Syndr 39:219-27. 2005..This shift is of concern as confidential HIV testing is the basis of US HIV surveillance systems... - Epidemiology of vancomycin-resistant Enterococcus faecium under a selective isolation policy at an urban county hospitalLisa G Winston
University of California, San Francisco/San Francisco General Hospital, 94110, USA
Am J Infect Control 30:400-6. 2002..VREF persisted in individual patients up to 46 months. CONCLUSIONS: The number of VREF infections in this facility has been low, despite appreciable colonization, for an extended period during which selective isolation was used... - Early virological response of zidovudine/lamivudine/abacavir for patients co-infected with HIV and tuberculosis in UgandaPadmini Srikantiah
HIV AIDS Division, San Francisco General Hospital, University of California, San Francisco, California, USA
AIDS 21:1972-4. 2007..No cases of hypersensitivity or immune reconstitution syndrome were observed. These data support the continuing evaluation of nucleoside-based antiretroviral regimens as an alternative treatment for this population... - High levels of adherence do not prevent accumulation of HIV drug resistance mutationsDavid R Bangsberg
Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, San Francisco General Hospital, California, USA
AIDS 17:1925-32. 2003..Exceptionally high levels of adherence will not prevent population levels of drug resistance... - Measuring adherence to antiretroviral therapy in a diverse population using a visual analogue scaleThomas P Giordano
Department of Medicine, Baylor College of Medicine, Houston, Texas, USA
HIV Clin Trials 5:74-9. 2004..Given its simplicity, the visual analogue scale adherence instrument will be useful in research and may be useful in routine patient care... - False-positive results of enzyme immunoassays for human immunodeficiency virus in patients with uncomplicated malariaAnne F Gasasira
Department of Medicine, Makerere University Medical School, Kampala, Uganda
J Clin Microbiol 44:3021-4. 2006..We found poor positive predictive values (53% and 76%), particularly with younger age. Combining EIAs eliminated false positives but missed 21% of true positives. Performance of HIV EIAs in malaria may be unsatisfactory... - High prevalence of methicillin-resistant Staphylococcus aureus in emergency department skin and soft tissue infectionsBradley W Frazee
Department of Emergency Medicine, Alameda County Medical Center Highland Campus, Oakland, CA 94602, USA
Ann Emerg Med 45:311-20. 2005.... - Effects of trimethoprim-sulfamethoxazole and insecticide-treated bednets on malaria among HIV-infected Ugandan childrenMoses R Kamya
Makerere University Medical School, Kampala, Uganda
AIDS 21:2059-66. 2007..The efficacy of TMP/SMX may be diminished where antifolate resistance to malaria is high. We evaluated the efficacy of these interventions for malaria prevention among Ugandan children... - HIV-1 infection in patients referred for malaria blood smears at government health clinics in UgandaLisa M Bebell
Columbia University College of Physicians and Surgeons, New York, NY, USA
J Acquir Immune Defic Syndr 46:624-30. 2007..In children, the relationship between HIV and malaria is less clear. We investigated the relationship between malaria and HIV-1 infection among adults and children referred for malaria blood smears at government health clinics in Uganda... - HIV RNA suppression among HIV-infected Ugandan children with measlesTheodore D Ruel
J Acquir Immune Defic Syndr 48:225-7. 2008
Research Grants
- Family-Based HIV VCT in Patients at Risk for TBEdwin Charlebois; Fiscal Year: 2007..3) To investigate the effectiveness of Home-based and TB Clinic-based VCT in linking HIV infected persons among the 600 randomized households to HIV medical care and social support. ..
- Family-Based HIV VCT in Patients at Risk for TBEDWIN DUNCAN CHARLEBOIS; Fiscal Year: 2010..3) To investigate the effectiveness of Home-based and TB Clinic-based VCT in linking HIV infected persons among the 600 randomized households to HIV medical care and social support. ..