L L Chao

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Experience-dependent modulation of category-related cortical activity
    Linda L Chao
    Laboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, MD, USA
    Cereb Cortex 12:545-51. 2002
  2. doi request reprint Regional cerebral volumes in veterans with current versus remitted posttraumatic stress disorder
    Linda Chao
    Department of Radiology, University of California, San Francisco 94121, USA
    Psychiatry Res 213:193-201. 2013
  3. doi request reprint Effects of post-traumatic stress disorder on occipital lobe function and structure
    Linda L Chao
    Department of Radiology and Biomedical Imaging, University of California, USA
    Neuroreport 23:412-9. 2012
  4. doi request reprint Effects of low-level sarin and cyclosarin exposure and Gulf War Illness on brain structure and function: a study at 4T
    Linda L Chao
    Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA
    Neurotoxicology 32:814-22. 2011
  5. pmc Effects of low-level exposure to sarin and cyclosarin during the 1991 Gulf War on brain function and brain structure in US veterans
    Linda L Chao
    Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Affairs Medical Center, 4150 Clement Street, 114 M, San Francisco, CA 94121, USA
    Neurotoxicology 31:493-501. 2010
  6. pmc ASL perfusion MRI predicts cognitive decline and conversion from MCI to dementia
    Linda L Chao
    Center for Imaging of Neurodegenerative Disease, San Francisco, CA, USA
    Alzheimer Dis Assoc Disord 24:19-27. 2010
  7. pmc Patterns of cerebral hypoperfusion in amnestic and dysexecutive MCI
    Linda L Chao
    Center for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Alzheimer Dis Assoc Disord 23:245-52. 2009
  8. pmc Patterns of white matter atrophy in frontotemporal lobar degeneration
    Linda L Chao
    Center for Imaging of Neurodegenerative Diseases, San Francisco Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Arch Neurol 64:1619-24. 2007
  9. pmc Evidence of neurodegeneration in brains of older adults who do not yet fulfill MCI criteria
    L L Chao
    Center for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center, San Francisco, CA 94121, USA
    Neurobiol Aging 31:368-77. 2010
  10. pmc Brain atrophy associated with baseline and longitudinal measures of cognition
    V A Cardenas
    San Francisco Veterans Affairs Medical Center, USA
    Neurobiol Aging 32:572-80. 2011

Detail Information

Publications24

  1. ncbi request reprint Experience-dependent modulation of category-related cortical activity
    Linda L Chao
    Laboratory of Brain and Cognition, National Institute of Mental Health, Bethesda, MD, USA
    Cereb Cortex 12:545-51. 2002
    ..Together, these findings suggest that category-related activations reflect the retrieval of information about category-specific features and attributes...
  2. doi request reprint Regional cerebral volumes in veterans with current versus remitted posttraumatic stress disorder
    Linda Chao
    Department of Radiology, University of California, San Francisco 94121, USA
    Psychiatry Res 213:193-201. 2013
    ....
  3. doi request reprint Effects of post-traumatic stress disorder on occipital lobe function and structure
    Linda L Chao
    Department of Radiology and Biomedical Imaging, University of California, USA
    Neuroreport 23:412-9. 2012
    ..These findings suggest that PTSD adversely affects occipital lobe volume but not the reactivity of the lateral occipital complex to generally aversive, trauma nonspecific stimuli...
  4. doi request reprint Effects of low-level sarin and cyclosarin exposure and Gulf War Illness on brain structure and function: a study at 4T
    Linda L Chao
    Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Affairs Medical Center, San Francisco, CA, USA
    Neurotoxicology 32:814-22. 2011
    ..5T MR scanner. In this study, we reexamine the relationship between GB/GF exposure and volumetric measurements of gross neuroanatomical structures in a different cohort of GW veterans on a 4T MR scanner...
  5. pmc Effects of low-level exposure to sarin and cyclosarin during the 1991 Gulf War on brain function and brain structure in US veterans
    Linda L Chao
    Center for Imaging of Neurodegenerative Diseases, San Francisco Veterans Affairs Medical Center, 4150 Clement Street, 114 M, San Francisco, CA 94121, USA
    Neurotoxicology 31:493-501. 2010
    ..The goal of the current study is to determine the generalizability of these findings in another cohort of GW veterans with suspected GB/GF exposure...
  6. pmc ASL perfusion MRI predicts cognitive decline and conversion from MCI to dementia
    Linda L Chao
    Center for Imaging of Neurodegenerative Disease, San Francisco, CA, USA
    Alzheimer Dis Assoc Disord 24:19-27. 2010
    ..03). These results suggest that hypoperfusion as detected by ASL-MRI can predict subsequent clinical, functional, and cognitive decline and may be useful for identifying candidates for future Alzheimer disease treatment trials...
  7. pmc Patterns of cerebral hypoperfusion in amnestic and dysexecutive MCI
    Linda L Chao
    Center for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center, 4150 Clement Street, San Francisco, CA 94121, USA
    Alzheimer Dis Assoc Disord 23:245-52. 2009
    ..These data further suggest that cognitive impairment in MCI is related to cerebral hypoperfusion...
  8. pmc Patterns of white matter atrophy in frontotemporal lobar degeneration
    Linda L Chao
    Center for Imaging of Neurodegenerative Diseases, San Francisco Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Arch Neurol 64:1619-24. 2007
    ..Structural magnetic resonance imaging (MRI) has been used to investigate the in vivo pathology of frontotemporal lobar degeneration. However, few neuroimaging studies have focused on white matter (WM) alterations in this disease...
  9. pmc Evidence of neurodegeneration in brains of older adults who do not yet fulfill MCI criteria
    L L Chao
    Center for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Center, San Francisco, CA 94121, USA
    Neurobiol Aging 31:368-77. 2010
    ....
  10. pmc Brain atrophy associated with baseline and longitudinal measures of cognition
    V A Cardenas
    San Francisco Veterans Affairs Medical Center, USA
    Neurobiol Aging 32:572-80. 2011
    ..These findings suggest that baseline volumes of prefrontal and temporal regions may underlie continuing cognitive decline due to aging, pathology, or both in non-demented elderly individuals...
  11. pmc Evidence for functional specialization of hippocampal subfields detected by MR subfield volumetry on high resolution images at 4 T
    S G Mueller
    Center for Imaging of Neurodegenerative Diseases, San Francisco VAMC, San Francisco, CA 94121, USA
    Neuroimage 56:851-7. 2011
    ..These preliminary findings demonstrate that subfield volumetry has the potential to study non invasively subfield specific memory functions...
  12. pmc Reduced medial temporal lobe N-acetylaspartate in cognitively impaired but nondemented patients
    L L Chao
    Magnetic Resonance Unit, San Francisco Veterans Affairs Medical Center, 4150 Clement Street, 116R, San Francisco, CA 94121, USA
    Neurology 64:282-9. 2005
    ..Because NAA is considered a marker of neuronal integrity, reduced medial temporal and parietal lobe NAA could be an early indication of dementia-related pathology in elderly individuals...
  13. pmc Clinical-neuroimaging characteristics of dysexecutive mild cognitive impairment
    Judy Pa
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA 94117, USA
    Ann Neurol 65:414-23. 2009
    ..The goal of the study was to compare clinical and neuroimaging characteristics of two single-domain MCI subgroups: amnestic MCI and dysexecutive MCI...
  14. pmc Evidence for ongoing brain injury in human immunodeficiency virus-positive patients treated with antiretroviral therapy
    V A Cardenas
    University of California, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    J Neurovirol 15:324-33. 2009
    ..Therefore, HIV+ individuals on ART should be monitored for cognitive decline, and treatments that reduce ongoing neurological injury should be considered...
  15. pmc Effects of heavy drinking, binge drinking, and family history of alcoholism on regional brain metabolites
    D J Meyerhoff
    Department of Radiology, University of California San Francisco, San Francisco, California, USA
    Alcohol Clin Exp Res 28:650-61. 2004
    ....
  16. ncbi request reprint Abnormal CNV in chronic heavy drinkers
    Linda L Chao
    Magnetic Resonance Unit, 116R San Francisco VA Medical Center, University of California San Francisco, 4150 Clement Street, San Francisco, CA 94121, USA
    Clin Neurophysiol 114:2081-95. 2003
    ..We used the contingent negative variation (CNV), a slow negative shift in the human electroencephalogram, to investigate the effects of heavy chronic alcohol use on frontal lobe function...
  17. pmc Abnormal contingent negative variation in HIV patients receiving antiretroviral therapy
    Linda L Chao
    Magnetic Resonance Unit, San Francisco Veterans Affairs Medical Center, 4150 Clement Street, 116R, San Francisco, CA 94121, USA
    Neuroreport 14:2111-5. 2003
    ..However, the benefits of antiretroviral therapy on immune function appear to facilitate neurocognitive performance...
  18. pmc Using automated morphometry to detect associations between ERP latency and structural brain MRI in normal adults
    Valerie A Cardenas
    Magnetic Resonance Unit, San Francisco Veterans Administration Medical Center, San Francisco, California 94121, USA
    Hum Brain Mapp 25:317-27. 2005
    ..These results imply that the WM connectivity between generators influences P3b latency more than the generators themselves do...
  19. pmc ERP evidence of impaired central nervous system function in virally suppressed HIV patients on antiretroviral therapy
    Linda L Chao
    Magnetic Resonance Unit, Department of Radiology, San Francisco Veterans Affairs Medical Center, and Department of Radiology, University of California, San Francisco, 94121, USA
    Clin Neurophysiol 115:1583-91. 2004
    ..To examine the effects of human immunodeficiency virus (HIV) on central nervous system (CNS) function in patients receiving antiretroviral therapy (ART) who have suppressed viral loads...
  20. ncbi request reprint White matter lesions are associated with cortical atrophy more than entorhinal and hippocampal atrophy
    An Tao Du
    Magnetic Resonance Unit 114M, Department of Veterans Affairs Medical Center, 4150, Clement Street, San Francisco, CA 94121, USA
    Neurobiol Aging 26:553-9. 2005
    ..Further, AD pathology and subcortical vascular disease may independently affect cortical atrophy...
  21. pmc Deformation-based morphometry reveals brain atrophy in frontotemporal dementia
    Valerie A Cardenas
    Magnetic Resonance Unit, San Francisco Veterans Affairs Medical Center, CA 94121, USA
    Arch Neurol 64:873-7. 2007
    ..To compare deformation-based maps of local anatomical size between subjects with frontotemporal dementia (FTD) and healthy subjects to identify regions of the brain involved in FTD...
  22. ncbi request reprint Prediction of conversion from mild cognitive impairment to Alzheimer disease based on bayesian data mining with ensemble learning
    R Chen
    Department of Radiology, University of Pennsylvania Philadelphia, PA, USA
    Neuroradiol J 25:5-16. 2012
    ..63 and specificity was 0.89. We validated the generated predictive model with an independent data set constructed from the Alzheimer Disease Neuroimaging Initiative database, and again found high predictive accuracy (0.75). ..
  23. ncbi request reprint Prefrontal and posterior cortical activation during auditory working memory
    L L Chao
    Department of Neurology and Center for Neuroscience, University of California, Davis VAMC Department of Neurology 127, Martinez 94553, USA
    Brain Res Cogn Brain Res 4:27-37. 1996
    ..Taken together these findings provide evidence of differential activation of distributed neural activity during non-linguistic auditory memory...
  24. pmc Age effects on atrophy rates of entorhinal cortex and hippocampus
    An Tao Du
    Magnetic Resonance Unit 114M, Department of Veterans Affairs Medical Center, 4150, Clement Street, San Francisco, CA 94121, USA
    Neurobiol Aging 27:733-40. 2006
    ..In conclusion, age and presence of lacunes should be taken into consideration in imaging studies of CN subjects and AD patients to predict AD progression and assess the response to treatment trials...