L Chao

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Distribution of spontaneous mutants and inferences about the replication mode of the RNA bacteriophage phi6
    Lin Chao
    Section of Ecology, Behavior and Evolution, Division of Biology, University of California, San Diego, La Jolla, California 92093 0116, USA
    J Virol 76:3276-81. 2002
  2. ncbi request reprint Kin selection and parasite evolution: higher and lower virulence with hard and soft selection
    L Chao
    Department of Biology, University of California San Diego 92093, USA
    Q Rev Biol 75:261-75. 2000
  3. pmc Hybrid frequencies confirm limit to coinfection in the RNA bacteriophage phi6
    P E Turner
    Department of Biology, University of Maryland, College Park, Maryland 20742, USA
    J Virol 73:2420-4. 1999
  4. pmc Sex and the evolution of intrahost competition in RNA virus phi6
    P E Turner
    Department of Biology, University of Maryland, College Park, Maryland 20742, USA
    Genetics 150:523-32. 1998
  5. ncbi request reprint Prisoner's dilemma in an RNA virus
    P E Turner
    Department of Biology, University of Maryland, College Park 20742, USA
    Nature 398:441-3. 1999
  6. ncbi request reprint Chemostat modeling of Escherichia coli persistence in conventionalized mono-associated and streptomycin-treated mice
    C Rang
    Department of Biology, University of California, San Diego, La Jolla, CA 92093 0116, USA
    Can J Microbiol 47:86-90. 2001
  7. ncbi request reprint Functional origins of fitness effect-sizes of compensatory mutations in the DNA bacteriophage phiX174
    Art F Y Poon
    Section of Ecology, Behavior, and Evolution, Division of Biological Sciences, University of California San Diego, La Jolla, California 92037, USA
    Evolution 60:2032-43. 2006
  8. pmc The rate of compensatory mutation in the DNA bacteriophage phiX174
    Art Poon
    Division of Biological Sciences, Section of Ecology, Behavior and Evolution, University of California, San Diego, California 92093 0116, USA
    Genetics 170:989-99. 2005
  9. pmc The coupon collector and the suppressor mutation: estimating the number of compensatory mutations by maximum likelihood
    Art Poon
    Division of Biological Sciences, University of California, San Diego, California 92093 0116, USA
    Genetics 170:1323-32. 2005
  10. pmc Drift increases the advantage of sex in RNA bacteriophage Phi6
    Art Poon
    Division of Biology, University of California, San Diego, California 92093, USA
    Genetics 166:19-24. 2004

Detail Information

Publications23

  1. pmc Distribution of spontaneous mutants and inferences about the replication mode of the RNA bacteriophage phi6
    Lin Chao
    Section of Ecology, Behavior and Evolution, Division of Biology, University of California, San Diego, La Jolla, California 92093 0116, USA
    J Virol 76:3276-81. 2002
    ..We discuss whether different replication modes may confer an adaptive advantage to viruses...
  2. ncbi request reprint Kin selection and parasite evolution: higher and lower virulence with hard and soft selection
    L Chao
    Department of Biology, University of California San Diego 92093, USA
    Q Rev Biol 75:261-75. 2000
    ..We recognize that hard selection for virulence is more difficult to document, but we take our results to suggest that a kin selection model with soft selection may have general applicability...
  3. pmc Hybrid frequencies confirm limit to coinfection in the RNA bacteriophage phi6
    P E Turner
    Department of Biology, University of Maryland, College Park, Maryland 20742, USA
    J Virol 73:2420-4. 1999
    ..We discuss whether phage phi6 has evolved an optimal limit that balances the costly and beneficial fitness effects associated with multiple infections...
  4. pmc Sex and the evolution of intrahost competition in RNA virus phi6
    P E Turner
    Department of Biology, University of Maryland, College Park, Maryland 20742, USA
    Genetics 150:523-32. 1998
    ..Our findings indicate that high levels of coinfection exceed an optimum where sex may be beneficial to populations of phi6, and suggest that genetic conflicts can evolve in RNA viruses...
  5. ncbi request reprint Prisoner's dilemma in an RNA virus
    P E Turner
    Department of Biology, University of Maryland, College Park 20742, USA
    Nature 398:441-3. 1999
    ..Because the low-multiplicity phage did not evolve lowered fitness, we attribute the evolution of selfishness to the lack of clonal structure and the mixing of unrelated genotypes at high multiplicity...
  6. ncbi request reprint Chemostat modeling of Escherichia coli persistence in conventionalized mono-associated and streptomycin-treated mice
    C Rang
    Department of Biology, University of California, San Diego, La Jolla, CA 92093 0116, USA
    Can J Microbiol 47:86-90. 2001
    ..coli populations is promoted by species diversity. We propose that a mechanism for the persistence may be the presence of new E. coli niches created by keystone species in the more diverse flora...
  7. ncbi request reprint Functional origins of fitness effect-sizes of compensatory mutations in the DNA bacteriophage phiX174
    Art F Y Poon
    Section of Ecology, Behavior, and Evolution, Division of Biological Sciences, University of California San Diego, La Jolla, California 92037, USA
    Evolution 60:2032-43. 2006
    ....
  8. pmc The rate of compensatory mutation in the DNA bacteriophage phiX174
    Art Poon
    Division of Biological Sciences, Section of Ecology, Behavior and Evolution, University of California, San Diego, California 92093 0116, USA
    Genetics 170:989-99. 2005
    ..We estimate that about half of all compensatory mutations are located extragenically in this organism...
  9. pmc The coupon collector and the suppressor mutation: estimating the number of compensatory mutations by maximum likelihood
    Art Poon
    Division of Biological Sciences, University of California, San Diego, California 92093 0116, USA
    Genetics 170:1323-32. 2005
    ..This is the first attempt to characterize the overall diversity of compensatory mutations, identifying a consistent and accurate prior distribution of compensatory mutation diversity for theoretical evolutionary models...
  10. pmc Drift increases the advantage of sex in RNA bacteriophage Phi6
    Art Poon
    Division of Biology, University of California, San Diego, California 92093, USA
    Genetics 166:19-24. 2004
    ..This is the first empirical evidence that the advantage of sex during adaptation increases with the intensity of drift...
  11. ncbi request reprint Evolution of cooperation: two for one?
    Martin Ackermann
    Division of Biological Sciences, University of California, San Diego, La Jolla, California 92093, USA
    Curr Biol 14:R73-4. 2004
    ..How can cooperation thrive in a selfish world? Recent evolution experiments show how bacteria themselves can generate conditions that make cooperation a winning strategy. At least in the short term...
  12. ncbi request reprint Fitness cost of the green fluorescent protein in gastrointestinal bacteria
    Camilla Rang
    Division of Biology, University of California, San Diego, La Jolla, CA 92093 0116, USA
    Can J Microbiol 49:531-7. 2003
    ....
  13. pmc Epistasis and its relationship to canalization in the RNA virus phi 6
    Christina L Burch
    Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA
    Genetics 167:559-67. 2004
    ..In addition, our results suggest that genetic and environmental canalization have the same developmental basis and finally that an understanding of the nature of epistasis may first require an understanding of the nature of canalization...
  14. pmc Widespread genetic exchange among terrestrial bacteriophages
    Olin K Silander
    Department of Biological Sciences, University of California at San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Proc Natl Acad Sci U S A 102:19009-14. 2005
    ..This extraordinary rate of genetic exchange between highly unrelated individuals is unprecedented in any taxa. We discuss our results in light of the biological species concept applied to viruses...
  15. pmc Understanding the evolutionary fate of finite populations: the dynamics of mutational effects
    Olin K Silander
    Division of Biology, University of California San Diego, La Jolla, California, United States of America
    PLoS Biol 5:e94. 2007
    ..In contrast, the size of mutational effects changes little even as organismal fitness changes over several orders of magnitude. These findings have significant implications for the dynamics of adaptation...
  16. ncbi request reprint Evolvability of an RNA virus is determined by its mutational neighbourhood
    C L Burch
    Department of Biology, University of California, San Diego, La Jolla 92093 0116, USA
    Nature 406:625-8. 2000
    ..Thus, the evolvability of phi6 is constrained by the distribution of its mutational neighbours, despite the fact that this phage has the characteristic high mutation rate of RNA viruses...
  17. pmc Amelioration of the cost of conjugative plasmid carriage in Eschericha coli K12
    Cecilia Dahlberg
    Department of Biology, University of California, San Diego, California 92093, USA
    Genetics 165:1641-9. 2003
    ..Our results suggest that once a conjugative bacterial plasmid has invaded a bacterial population it will remain even if the original selection is discontinued...
  18. ncbi request reprint Rapid evolutionary escape by large populations from local fitness peaks is likely in nature
    Daniel M Weinreich
    Department of Organismic and Evolutionary Biology, Harvard University, 16 Divinity Avenue, Cambridge, Massachusetts 02138, USA
    Evolution 59:1175-82. 2005
    ..Thus, counterintuitively, mass selection alone offers a biologically realistic resolution to the problem of evolutionary escape from local fitness peaks in natural populations...
  19. ncbi request reprint Perspective: Evolution and detection of genetic robustness
    J Arjan G M de Visser
    Department of Genetics, Wageningen University, Arboretumlaan 4, 6703 BD Wageningen, The Netherlands
    Evolution 57:1959-72. 2003
    ....
  20. pmc Co-infection weakens selection against epistatic mutations in RNA viruses
    Remy Froissart
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Genetics 168:9-19. 2004
    ..We discuss our results in light of virus disease management and the evolutionary advantage of haploidy in biological populations...
  21. pmc On the evolutionary origin of aging
    Martin Ackermann
    Institute of Integrative Biology, ETHZ, 8092 Zurich, Switzerland
    Aging Cell 6:235-44. 2007
    ..Aging might thus be a more fundamental aspect of cellular organisms than assumed so far...
  22. ncbi request reprint Perspective: Sign epistasis and genetic constraint on evolutionary trajectories
    Daniel M Weinreich
    Department of Organismic and Evolutionary Biology, Harvard University, 16 Divinity Avenue, Cambridge, Massachusetts 02138, USA
    Evolution 59:1165-74. 2005
    ..These theoretical and empirical considerations imply that strong genetic constraint on the selective accessibility of trajectories to high fitness genotypes may exist and suggest specific areas of investigation for future research...
  23. ncbi request reprint Escape from Prisoner's Dilemma in RNA phage phi6
    Paul E Turner
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut 06520, USA
    Am Nat 161:497-505. 2003
    ..We discuss mechanisms that may afford selfish genotypes an advantage during intrahost competition and the relevance in our system for alternative ecological interactions among viruses...