Richard Channick

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Safety and efficacy of inhaled treprostinil as add-on therapy to bosentan in pulmonary arterial hypertension
    Richard N Channick
    UCSD Medical Center, La Jolla, California 92037, USA
    J Am Coll Cardiol 48:1433-7. 2006
  2. ncbi request reprint Diagnosis and treatment of pulmonary arterial hypertension
    Richard Channick
    Division of Pulmonary and Critical Care, University of California, San Diego, 9300 Campus Point Drive, La Jolla, CA 92037, USA
    Cardiol Clin 22:441-52, vii. 2004
  3. ncbi request reprint Endothelin receptor antagonists in pulmonary arterial hypertension
    Richard N Channick
    Pulmonary and Critical Care Division, University of California, San Diego, California, USA
    J Am Coll Cardiol 43:62S-67S. 2004
  4. ncbi request reprint Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study
    R N Channick
    Division of Pulmonary and Critical Care Medicine, University of California, San Diego, CA, USA
    Lancet 358:1119-23. 2001
  5. ncbi request reprint Bosentan
    Kelly Chin
    Division of Pulmonary and Critical Care Medicine, University of California, San Diego, 9300 Campus Point Drive, La Jolla, CA 92037 7381, USA
    Expert Rev Cardiovasc Ther 2:175-82. 2004
  6. ncbi request reprint Long-term outcome after pulmonary thromboendarterectomy
    C J Archibald
    Division of Pulmonary and Critical Care Medicine and Division of Cardiothoracic Surgery, University of California, San Diego, San Diego, California, USA
    Am J Respir Crit Care Med 160:523-8. 1999
  7. ncbi request reprint Atrial septostomy as a bridge to lung transplantation in patients with severe pulmonary hypertension
    A Rothman
    Division of Pediatric Cardiology, University of California, San Diego, USA
    Am J Cardiol 84:682-6. 1999
  8. ncbi request reprint Chronic thromboembolic pulmonary hypertension
    P F Fedullo
    Division of Pulmonary and Critical Care, University of California, San Diego Medical Center, San Diego, California, USA
    Clin Chest Med 22:561-81. 2001
  9. ncbi request reprint Outpatient inhaled nitric oxide in a patient with idiopathic pulmonary fibrosis: a bridge to lung transplantation
    G L Yung
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Diego School of Medicine, San Diego, California 92103 8373, USA
    J Heart Lung Transplant 20:1224-7. 2001
  10. ncbi request reprint New and experimental therapies for pulmonary hypertension
    R N Channick
    Department of Medicine, Pulmonary and Critical Care Division, University of California, San Diego Medical Center, San Diego, California, USA
    Clin Chest Med 22:539-45. 2001

Detail Information

Publications24

  1. ncbi request reprint Safety and efficacy of inhaled treprostinil as add-on therapy to bosentan in pulmonary arterial hypertension
    Richard N Channick
    UCSD Medical Center, La Jolla, California 92037, USA
    J Am Coll Cardiol 48:1433-7. 2006
    ..This study evaluated the safety and efficacy of inhaled treprostinil as add-on therapy to oral bosentan in patients with pulmonary arterial hypertension (PAH)...
  2. ncbi request reprint Diagnosis and treatment of pulmonary arterial hypertension
    Richard Channick
    Division of Pulmonary and Critical Care, University of California, San Diego, 9300 Campus Point Drive, La Jolla, CA 92037, USA
    Cardiol Clin 22:441-52, vii. 2004
    ..Proper evaluation and understanding of determinants of severity in pulmonary arterial hypertension are necessary to guide appropriate therapy. This article discusses the diagnosis and treatment of this complex and multifactorial disease...
  3. ncbi request reprint Endothelin receptor antagonists in pulmonary arterial hypertension
    Richard N Channick
    Pulmonary and Critical Care Division, University of California, San Diego, California, USA
    J Am Coll Cardiol 43:62S-67S. 2004
    ..The selective endothelin receptor-A antagonists sitaxsentan and ambrisentan are currently undergoing investigation...
  4. ncbi request reprint Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study
    R N Channick
    Division of Pulmonary and Critical Care Medicine, University of California, San Diego, CA, USA
    Lancet 358:1119-23. 2001
    ..We describe the efficacy and safety of bosentan, a dual endothelin-receptor antagonist that can be taken orally, in patients with severe pulmonary hypertension...
  5. ncbi request reprint Bosentan
    Kelly Chin
    Division of Pulmonary and Critical Care Medicine, University of California, San Diego, 9300 Campus Point Drive, La Jolla, CA 92037 7381, USA
    Expert Rev Cardiovasc Ther 2:175-82. 2004
    ..Ease of administration of bosentan with twice-daily oral dosing will provide many patients with pulmonary hypertension an option for treatment without the risks and discomforts of continuous intravenous medication...
  6. ncbi request reprint Long-term outcome after pulmonary thromboendarterectomy
    C J Archibald
    Division of Pulmonary and Critical Care Medicine and Division of Cardiothoracic Surgery, University of California, San Diego, San Diego, California, USA
    Am J Respir Crit Care Med 160:523-8. 1999
    ..These data indicate that PTE offers most CTEPH patients substantial improvement in survival, function, and quality of life, with minimal disease-related health care utilization...
  7. ncbi request reprint Atrial septostomy as a bridge to lung transplantation in patients with severe pulmonary hypertension
    A Rothman
    Division of Pediatric Cardiology, University of California, San Diego, USA
    Am J Cardiol 84:682-6. 1999
    ..Six patients did not have clinical improvement after septostomy. Atrial septostomy improves the hemodynamic status and may be useful as a bridge to lung transplantation in selected patients with pulmonary hypertension...
  8. ncbi request reprint Chronic thromboembolic pulmonary hypertension
    P F Fedullo
    Division of Pulmonary and Critical Care, University of California, San Diego Medical Center, San Diego, California, USA
    Clin Chest Med 22:561-81. 2001
    ..It also provides a unique opportunity to evaluate pharmacologic interventions designed to prevent or diminish the occurrence of acute lung injury and postoperative management strategies designed to minimize its impact...
  9. ncbi request reprint Outpatient inhaled nitric oxide in a patient with idiopathic pulmonary fibrosis: a bridge to lung transplantation
    G L Yung
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Diego School of Medicine, San Diego, California 92103 8373, USA
    J Heart Lung Transplant 20:1224-7. 2001
    ..Exercise study and two-dimensional echocardiogram, after 3 months of inhaled NO, demonstrated continued benefits of INO for improvement of arterial oxygenation, pulmonary arterial pressure and exercise tolerance...
  10. ncbi request reprint New and experimental therapies for pulmonary hypertension
    R N Channick
    Department of Medicine, Pulmonary and Critical Care Division, University of California, San Diego Medical Center, San Diego, California, USA
    Clin Chest Med 22:539-45. 2001
    ..The development of agents that target the known endothelial and nonendothelial defects in patients with PPH is well underway. Clinicians are witnessing an exciting new era for physicians and patients dealing with this disease...
  11. doi request reprint Rituximab treatment of pulmonary arterial hypertension associated with systemic lupus erythematosus: a case report
    S Hennigan
    Department of Medicine, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Lupus 17:754-6. 2008
    ....
  12. ncbi request reprint Comparison of impedance cardiography to direct Fick and thermodilution cardiac output determination in pulmonary arterial hypertension
    Gordon L Yung
    Division of Pulmonary and Critical Care Medicine, University of California San Diego Medical Center, San Diego, CA 92103 8373, USA
    Congest Heart Fail 10:7-10. 2004
    ..TD was 0.84, 0.89, and 0.80, respectively). ICG provides an accurate, useful, and cost-effective method for determining CO in pulmonary hypertension patients, and is a potential tool for following responses to therapeutic interventions...
  13. doi request reprint Exercise in patients with pulmonary arterial hypertension
    Smita A Desai
    University of California San Diego Medical Center, 200 W Arbor Dr, MC 8373, San Diego, CA 92103 corrected USA
    J Cardiopulm Rehabil Prev 28:12-6. 2008
    ..The evidence suggesting that exercise may be safe in these patients is summarized and a potential exercise prescription is suggested...
  14. ncbi request reprint Central venous blood oxygen saturation monitoring in patients with chronic pulmonary arterial hypertension treated with continuous IV epoprostenol: correlation with measurements of hemodynamics and plasma brain natriuretic peptide levels
    Kelly M Chin
    Department of Internal Medicine, University of Texas Southwestern Pulmonary Hypertension Program, 5909 Harry Hines Blvd, Dallas, TX 75235 9254, USA
    Chest 132:786-92. 2007
    ....
  15. ncbi request reprint Function of Kv1.5 channels and genetic variations of KCNA5 in patients with idiopathic pulmonary arterial hypertension
    Carmelle V Remillard
    Department of Medicine, University of California San Diego, 9500 Gilman Dr, MC 0725, La Jolla, CA 92093 0725, USA
    Am J Physiol Cell Physiol 292:C1837-53. 2007
    ..g., nicotine and ET-1); 2) novel SNPs in KCNA5 are present in IPAH patients; and 3) SNPs in the promoter and translated regions of KCNA5 may underlie the altered expression and/or function of Kv1.5 channels in PASMC from IPAH patients...
  16. ncbi request reprint Effects of the dual endothelin receptor antagonist bosentan in patients with pulmonary arterial hypertension: a 1-year follow-up study
    Olivier Sitbon
    Service de Pneumologie RĂ©animation Respiratoire, Hopital Antoine Beclere, 157, Avenue de la Porte Trivaux, F 92141 Clamart Cedex, France
    Chest 124:247-54. 2003
    ..We report on the long-term safety and efficacy of bosentan treatment in patients with pulmonary arterial hypertension (PAH)...
  17. ncbi request reprint Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension
    Vallerie V McLaughlin
    The University of Michigan Health System, Ann Arbor, Michigan, USA
    Am J Respir Crit Care Med 174:1257-63. 2006
    ..Small, open-label studies suggest that combinations of existing therapies may be effective for pulmonary arterial hypertension (PAH)...
  18. ncbi request reprint Endothelin antagonism in pulmonary arterial hypertension
    Stephen H Lee
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California, San Diego, La Jolla, CA 92037, USA
    Semin Respir Crit Care Med 26:402-8. 2005
    ..This review provides an overview of endothelin biology and the clinical use of ERAs for the treatment of PAH. The use of ERAs for other forms of pulmonary hypertension will not be reviewed here...
  19. ncbi request reprint Successful withdrawal of long-term epoprostenol therapy for pulmonary arterial hypertension
    Nick H Kim
    Pulmonary Vascular Center, University of California, San Diego, CA, La Jolla 92037, USA
    Chest 124:1612-5. 2003
    ..IV epoprostenol treatment of pulmonary arterial hypertension (PAH) has been believed to require an indefinite duration of therapy..
  20. ncbi request reprint Pulmonary endarterectomy: experience and lessons learned in 1,500 cases
    Stuart W Jamieson
    Division of Cardiothoracic Surgery, Department of Anesthesia, UCSD Medical Center, San Diego, California, USA
    Ann Thorac Surg 76:1457-62; discussion 1462-4. 2003
    ..With the increased recognition of the disease and the success of operative therapy, however, more than 1,400 operations have been done since 1990 at our center...
  21. ncbi request reprint Preoperative partitioning of pulmonary vascular resistance correlates with early outcome after thromboendarterectomy for chronic thromboembolic pulmonary hypertension
    Nick H S Kim
    University of California, San Diego, 9300 Campus Point Dr, M C 7381, La Jolla, CA 92037 1300, USA
    Circulation 109:18-22. 2004
    ..We postulated that pulmonary arterial occlusion pressure waveform analysis, a technique that has been used for partitioning pulmonary vascular resistance, might identify CTEPH patients with significant distal, small-vessel disease...
  22. ncbi request reprint Decreased plasma neurohormones and improved cardiac performance after surgical treatment of chronic pulmonary embolism
    Igor I Tulevski
    Department of Cardiology, University of Amsterdam, The Netherlands
    Ann Thorac Surg 76:287-90. 2003
    ..Monitoring of changes in these parameters may provide quantitative follow-up of right ventricular function in these patients...
  23. ncbi request reprint Is methamphetamine use associated with idiopathic pulmonary arterial hypertension?
    Kelly M Chin
    Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, St Paul University Hospital, Dallas, TX, USA
    Chest 130:1657-63. 2006
    ....
  24. ncbi request reprint Surgical treatments/interventions for pulmonary arterial hypertension: ACCP evidence-based clinical practice guidelines
    Ramona L Doyle
    Pulmonary and Critical Care Medicine, H3147 Stanford University School of Medicine, Palo Alto, CA 94305, USA
    Chest 126:63S-71S. 2004
    ..This chapter will provide evidence-based recommendations for the selection and timing of surgical and interventional treatments of PAH for physicians involved in the care of these complex patients...