Yingzi Chang

Summary

Affiliation: University of Tennessee
Country: USA

Publications

  1. ncbi request reprint Counter-regulatory function of protein tyrosine phosphatase 1B in platelet-derived growth factor- or fibroblast growth factor-induced motility and proliferation of cultured smooth muscle cells and in neointima formation
    Yingzi Chang
    Department of Physiology, University of Tennessee Health Science Center, Memphis, TN, USA
    Arterioscler Thromb Vasc Biol 26:501-7. 2006
  2. pmc Chronic insulin treatment amplifies PDGF-induced motility in differentiated aortic smooth muscle cells by suppressing the expression and function of PTP1B
    Daming Zhuang
    Dept of Physiology, Univ of Tennessee, Memphis, TN 38163, USA
    Am J Physiol Heart Circ Physiol 295:H163-73. 2008
  3. pmc Chronic insulin treatment suppresses PTP1B function, induces increased PDGF signaling, and amplifies neointima formation in the balloon-injured rat artery
    Qinghua Pu
    Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Am J Physiol Heart Circ Physiol 296:H132-9. 2009
  4. ncbi request reprint Increase of PTP levels in vascular injury and in cultured aortic smooth muscle cells treated with specific growth factors
    Yingzi Chang
    Department of Physiology, University of Tennessee Health Science Center, 894 Union Ave, Memphis, TN 38163, USA
    Am J Physiol Heart Circ Physiol 287:H2201-8. 2004
  5. ncbi request reprint Nitric oxide attenuates IGF-I-induced aortic smooth muscle cell motility by decreasing Rac1 activity: essential role of PTP-PEST and p130cas
    Alice Corina Ceacareanu
    Department of Physiology, University of Tennessee Health Science Center, 894 Union Ave, Memphis, 38163, USA
    Am J Physiol Cell Physiol 290:C1263-70. 2006
  6. ncbi request reprint Nitric oxide-induced motility in aortic smooth muscle cells: role of protein tyrosine phosphatase SHP-2 and GTP-binding protein Rho
    Yingzi Chang
    Department of Physiology and Vascular Biology Center, University of Tennessee, Memphis 38163, USA
    Circ Res 91:390-7. 2002

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Counter-regulatory function of protein tyrosine phosphatase 1B in platelet-derived growth factor- or fibroblast growth factor-induced motility and proliferation of cultured smooth muscle cells and in neointima formation
    Yingzi Chang
    Department of Physiology, University of Tennessee Health Science Center, Memphis, TN, USA
    Arterioscler Thromb Vasc Biol 26:501-7. 2006
    ..The current study was designed to test the hypothesis that PTP1B attenuates PDGF- or FGF-induced motility and proliferation of cultured cells, as well as neointima formation in injured rat carotid arteries...
  2. pmc Chronic insulin treatment amplifies PDGF-induced motility in differentiated aortic smooth muscle cells by suppressing the expression and function of PTP1B
    Daming Zhuang
    Dept of Physiology, Univ of Tennessee, Memphis, TN 38163, USA
    Am J Physiol Heart Circ Physiol 295:H163-73. 2008
    ..These observations uncover novel mechanisms that explain how insulin amplifies the motogenic capacity of the pivotal growth factor PDGF...
  3. pmc Chronic insulin treatment suppresses PTP1B function, induces increased PDGF signaling, and amplifies neointima formation in the balloon-injured rat artery
    Qinghua Pu
    Department of Physiology, University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Am J Physiol Heart Circ Physiol 296:H132-9. 2009
    ..These observations support the hypothesis that hyperinsulinemia induces the suppression of PTP1B function, leading to enhanced PDGFR signaling and neointimal hyperplasia...
  4. ncbi request reprint Increase of PTP levels in vascular injury and in cultured aortic smooth muscle cells treated with specific growth factors
    Yingzi Chang
    Department of Physiology, University of Tennessee Health Science Center, 894 Union Ave, Memphis, TN 38163, USA
    Am J Physiol Heart Circ Physiol 287:H2201-8. 2004
    ..These results suggest that increased PDGF and bFGF levels, occurring after vascular injury, may induce expression of several PTPs...
  5. ncbi request reprint Nitric oxide attenuates IGF-I-induced aortic smooth muscle cell motility by decreasing Rac1 activity: essential role of PTP-PEST and p130cas
    Alice Corina Ceacareanu
    Department of Physiology, University of Tennessee Health Science Center, 894 Union Ave, Memphis, 38163, USA
    Am J Physiol Cell Physiol 290:C1263-70. 2006
    ..Decreased Rac1 activity lowers intracellular H(2)O(2) levels, thus attenuating cell motility...
  6. ncbi request reprint Nitric oxide-induced motility in aortic smooth muscle cells: role of protein tyrosine phosphatase SHP-2 and GTP-binding protein Rho
    Yingzi Chang
    Department of Physiology and Vascular Biology Center, University of Tennessee, Memphis 38163, USA
    Circ Res 91:390-7. 2002
    ..The results may be of relevance to in vivo events such as neointimal formation, angiogenesis, and vasculogenesis...