Roger L Chang

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Deterministic graph-theoretic algorithm for detecting modules in biological interaction networks
    Roger L Chang
    University of California San Diego, La Jolla, San Diego, CA 92093 0412, USA
    Int J Bioinform Res Appl 6:101-19. 2010
  2. ncbi Network context and selection in the evolution to enzyme specificity
    Hojung Nam
    Department of Bioengineering, University of California San Diego, La Jolla, CA 92093 0412, USA
    Science 337:1101-4. 2012
  3. ncbi Drug off-target effects predicted using structural analysis in the context of a metabolic network model
    Roger L Chang
    Department of Bioengineering, University of California San Diego, La Jolla, California, United States of America
    PLoS Comput Biol 6:e1000938. 2010
  4. ncbi Metabolic network reconstruction of Chlamydomonas offers insight into light-driven algal metabolism
    Roger L Chang
    Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA
    Mol Syst Biol 7:518. 2011

Detail Information

Publications4

  1. ncbi Deterministic graph-theoretic algorithm for detecting modules in biological interaction networks
    Roger L Chang
    University of California San Diego, La Jolla, San Diego, CA 92093 0412, USA
    Int J Bioinform Res Appl 6:101-19. 2010
    ..dMoNet simultaneously processes structurally equivalent edges while preserving intuitive foundations of the MoNet algorithm and generates modules with full network coverage...
  2. ncbi Network context and selection in the evolution to enzyme specificity
    Hojung Nam
    Department of Bioengineering, University of California San Diego, La Jolla, CA 92093 0412, USA
    Science 337:1101-4. 2012
    ..Furthermore, these properties are conserved in Archaea and Eukarya. Thus, the metabolic network context and environmental conditions influence enzyme evolution toward high specificity...
  3. ncbi Drug off-target effects predicted using structural analysis in the context of a metabolic network model
    Roger L Chang
    Department of Bioengineering, University of California San Diego, La Jolla, California, United States of America
    PLoS Comput Biol 6:e1000938. 2010
    ..The methodology introduced herein has important implications for drug development and personalized medicine...
  4. ncbi Metabolic network reconstruction of Chlamydomonas offers insight into light-driven algal metabolism
    Roger L Chang
    Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA
    Mol Syst Biol 7:518. 2011
    ..The network offers insight into algal metabolism and potential for genetic engineering and efficient light source design, a pioneering resource for studying light-driven metabolism and quantitative systems biology...