Research Topics
Genomes and Genes
Species | Jeffrey S ChangSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Allergies and childhood leukemiaJeffrey S Chang
Department of Epidemiology and Biostatistics, 44 Page Street, University of California San Francisco, San Francisco, CA 94143 1215, USA
Blood Cells Mol Dis 42:99-104. 2009..In addition, the utilities of genetic and molecular studies to disentangle the association between allergies and childhood leukemia and to elucidate the biological mechanisms are also discussed...
Base excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African-AmericansJeffrey S Chang
Department of Epidemiology and Biostatistics, Division of Neuroepidemiology, University of California San Francisco, San Francisco, CA 94143 1215, USA
Carcinogenesis 30:78-87. 2009..This study suggests that there are genetic differences in the association between BER pathway and lung cancer between Latinos and African-Americans...- Parental social contact in the work place and the risk of childhood acute lymphoblastic leukaemiaJ S Chang
Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA
Br J Cancer 97:1315-21. 2007..Our data suggest that duration of parental occupation may be important when examining the association between parental social contact in the workplace and childhood leukaemia... - Pathway analysis of single-nucleotide polymorphisms potentially associated with glioblastoma multiforme susceptibility using random forestsJeffrey S Chang
Department of Epidemiology and Biostatistics, University of California, San Francisco, 44 Page Street, Suite 503, San Francisco, CA 94143 1215, USA
Cancer Epidemiol Biomarkers Prev 17:1368-73. 2008..Despite less than complete inclusion of genes and SNPs relevant to glioma and a small sample size, RF analysis identified one important biological pathway and several SNPs potentially associated with the development of glioblastoma... - Nucleotide excision repair genes and risk of lung cancer among San Francisco Bay Area Latinos and African AmericansJeffrey S Chang
Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA
Int J Cancer 123:2095-104. 2008..61; 95% CI: 0.42-0.88). Our study suggests different elements of the NER pathway may be important in the different ethnic groups resulting either from different linkage relationship, genetic backgrounds and/or exposure histories... - Genetic variants in the folate pathway and risk of childhood acute lymphoblastic leukemiaCatherine Metayer
School of Public Health, University of California, Berkeley, 1995 University Avenue, Suite 460, Berkeley, CA 94704 7392, USA
Cancer Causes Control 22:1243-58. 2011..We examined whether child's germline genetic variation in the folate pathway is associated with childhood acute lymphoblastic leukemia (ALL), and whether periconception maternal folate and alcohol intake modify the risk... - Maternal immunoglobulin E and childhood leukemiaJeffrey S Chang
Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA 94143 1215, USA
Cancer Epidemiol Biomarkers Prev 18:2221-7. 2009.... - Genetic polymorphisms in adaptive immunity genes and childhood acute lymphoblastic leukemiaJeffrey S Chang
Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA
Cancer Epidemiol Biomarkers Prev 19:2152-63. 2010..The lack of immune priming in early childhood may result in abnormal immune responses to infections later in life and increase ALL risk... - SNPLogic: an interactive single nucleotide polymorphism selection, annotation, and prioritization systemAlexander R Pico
Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA
Nucleic Acids Res 37:D803-9. 2009..We have found integration of SNP annotation in the context of pathway information and functional prediction scores to be a powerful approach to the analysis and interpretation of SNP-disease association data... - Haplotypes of DNA repair and cell cycle control genes, X-ray exposure, and risk of childhood acute lymphoblastic leukemiaAnand P Chokkalingam
Division of Epidemiology, School of Public Health, University of California Berkeley, 1995 University Avenue, Berkeley, CA 94704, USA
Cancer Causes Control 22:1721-30. 2011..These abnormalities may be influenced by altered DNA repair and cell cycle control processes... - Fetal growth and body size genes and risk of childhood acute lymphoblastic leukemiaAnand P Chokkalingam
School of Public Health, University of California Berkeley, Berkeley, CA, USA
Cancer Causes Control 23:1577-85. 2012..Additional studies are needed to confirm these findings and identify specific causal variants... - Variation in xenobiotic transport and metabolism genes, household chemical exposures, and risk of childhood acute lymphoblastic leukemiaAnand P Chokkalingam
Division of Epidemiology, UC Berkeley School of Public Health, University of California Berkeley, 1995 University Ave, Berkeley, CA 94704, USA
Cancer Causes Control 23:1367-75. 2012..We sought to evaluate the role of genes involved in xenobiotic transport and metabolism in childhood ALL risk, both alone and in conjunction with household chemical exposures previously found to be associated with childhood ALL risk... 
Parental smoking and the risk of childhood leukemiaJeffrey S Chang
School of Public Health, University of California, Berkeley, CA 94720 7380, USA
Am J Epidemiol 163:1091-100. 2006..004). These results strongly suggest that exposure to paternal preconception smoking alone or in combination with postnatal passive smoking may be important in the risk of childhood leukemia...- Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibilityMargaret Wrensch
Department of Neurological Surgery, University of California, San Francisco, San Francisco, California, USA
Nat Genet 41:905-8. 2009..85 x 10(-10). On 20q13.3, rs6010620 intronic to RTEL1 had discovery P = 1.5 x 10(-7), replication P = 0.00035 and combined P = 3.40 x 10(-9). For both SNPs, the direction of association was the same in discovery and replication phases... - Breast cancer and dietary factors in Taiwanese womenMarion M Lee
Department of Epidemiology and Biostatistics, University of California at San Francisco, MU 420 West, San Francisco, CA 94143 0560, USA
Cancer Causes Control 16:929-37. 2005..To examine the effect of the consumption of dietary factors on the risk of breast cancer in a case-control study in Taiwan... - NQO1 polymorphisms and de novo childhood leukemia: a HuGE review and meta-analysisNeela Guha
Division of Epidemiology, School of Public Health, University of California, Berkeley, California 94704, USA
Am J Epidemiol 168:1221-32. 2008..Therefore, further research is warranted on the role of NQO1 polymorphisms in the etiology of childhood leukemia, especially among MLL-positive leukemias... - Profound deficit of IL10 at birth in children who develop childhood acute lymphoblastic leukemiaJeffrey S Chang
Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA 94143 0520, USA
Cancer Epidemiol Biomarkers Prev 20:1736-40. 2011..The current study examines the association between neonatal cytokine profiles, a proxy measure for a child's prenatal immune development, and childhood ALL... - Parental smoking and childhood leukemiaJeffrey S Chang
Department of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA
Methods Mol Biol 472:103-37. 2009..g., asthma, respiratory tract infection, and otitis media) that are much more prevalent than childhood leukemia... - Complementary and alternative medicine use among men with prostate cancer in 4 ethnic populationsMarion M Lee
Department of Epidemiology and Biostatistics, University of California-San Francisco, Box 560, San Francisco, CA 94143-0560, USA
Am J Public Health 92:1606-9. 2002 - Analysis of 60 reported glioma risk SNPs replicates published GWAS findings but fails to replicate associations from published candidate-gene studiesKyle M Walsh
Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA
Genet Epidemiol 37:222-8. 2013..These results highlight that the deficiencies of the candidate-gene approach lay in selecting both appropriate genes and relevant SNPs within these genes... - Backtracking RAS mutations in high hyperdiploid childhood acute lymphoblastic leukemiaJoseph L Wiemels
Laboratory for Molecular Epidemiology, Department of Epidemiology and Biostatistics, and Helen Diller Comprehensive Cancer Center, University of California San Francisco, CA 94158, USA
Blood Cells Mol Dis 45:186-91. 2010..We posit a natural history for hyperdiploid leukemia in which prenatal mitotic catastrophe is followed by a postnatal RAS mutation to produce the leukemic cell phenotype... - Soy and isoflavone consumption in relation to prostate cancer risk in ChinaMarion M Lee
Department of Epidemiology and Biostatistics, University of California at San Francisco, 94143 0560, USA
Cancer Epidemiol Biomarkers Prev 12:665-8. 2003..Our results indicate a reduced risk of prostate cancer associated with consumption of soy foods and isoflavones. These findings should be confirmed in longitudinal follow-up studies in populations with varying risk of prostate cancer... - Complementary and alternative medicine use among patients attending a hospital dermatology clinic in TaiwanYu-Fu Chen
Department of Dermatology, Show Chwan Memorial Hospital, Changhua City, Taiwan
Int J Dermatol 42:616-21. 2003..Because some CAM may produce serious side-effects, dermatologists need to help and guide patients to assess the benefits and dangers of using CAM to treat dermatological conditions...