Siu Lung Chan

Summary

Affiliation: University of Vermont
Country: USA

Publications

  1. pmc Treatment for cerebral small vessel disease: effect of relaxin on the function and structure of cerebral parenchymal arterioles during hypertension
    Siu Lung Chan
    1Department of Neurological Sciences, University of Vermont, 149 Beaumont Ave, HSRF 416, Burlington, VT 05405, USA
    FASEB J 27:3917-27. 2013
  2. pmc Determination of PPARγ activity in adipose tissue and spleen
    Siu Lung Chan
    Department of Neurology, University of Vermont, Burlington, Vermont, USA
    J Immunoassay Immunochem 33:314-24. 2012
  3. pmc Relaxin causes selective outward remodeling of brain parenchymal arterioles via activation of peroxisome proliferator-activated receptor-γ
    Siu Lung Chan
    Department of Neurology, University of Vermont, Burlington, VT 05401 USA
    FASEB J 25:3229-39. 2011
  4. pmc Effect of pregnancy and nitric oxide on the myogenic vasodilation of posterior cerebral arteries and the lower limit of cerebral blood flow autoregulation
    Abbie C Chapman
    Neuroscience Graduate Program, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Reprod Sci 20:1046-54. 2013
  5. pmc Effect of PPARγ inhibition during pregnancy on posterior cerebral artery function and structure
    Siu Lung Chan
    Department of Neurology, University of Vermont Burlington, VT, USA
    Front Physiol 1:130. 2010
  6. pmc Effect of pregnancy on autoregulation of cerebral blood flow in anterior versus posterior cerebrum
    Marilyn J Cipolla
    Department of Neurology, University of Vermont, 149 Beaumont Ave, HSRF 416, Burlington, VT 05405, USA
    Hypertension 60:705-11. 2012
  7. ncbi request reprint Increased pressure-induced tone in rat parenchymal arterioles vs. middle cerebral arteries: role of ion channels and calcium sensitivity
    Marilyn J Cipolla
    Department of Neurological Sciences, University of Vermont, Burlington, Vermont Department of Pharmacology, University of Vermont, Burlington, Vermont and Department of Obstetrics, Gynecology and Reproductive Sciences, University of Vermont, Burlington, Vermont
    J Appl Physiol (1985) 117:53-9. 2014
  8. pmc Cerebral vascular adaptation to pregnancy and its role in the neurological complications of eclampsia
    Marilyn J Cipolla
    Department of Neurology, Univ of Vermont, 89 Beaumont Ave, Given C454, Burlington, VT 05405, USA
    J Appl Physiol (1985) 110:329-39. 2011

Collaborators

Detail Information

Publications8

  1. pmc Treatment for cerebral small vessel disease: effect of relaxin on the function and structure of cerebral parenchymal arterioles during hypertension
    Siu Lung Chan
    1Department of Neurological Sciences, University of Vermont, 149 Beaumont Ave, HSRF 416, Burlington, VT 05405, USA
    FASEB J 27:3917-27. 2013
    ..VEGF appears to be involved in remodeling of PAs, but not relaxin-induced increased distensibility...
  2. pmc Determination of PPARγ activity in adipose tissue and spleen
    Siu Lung Chan
    Department of Neurology, University of Vermont, Burlington, Vermont, USA
    J Immunoassay Immunochem 33:314-24. 2012
    ..Validation of the assay with each individual tissue is recommended...
  3. pmc Relaxin causes selective outward remodeling of brain parenchymal arterioles via activation of peroxisome proliferator-activated receptor-γ
    Siu Lung Chan
    Department of Neurology, University of Vermont, Burlington, VT 05401 USA
    FASEB J 25:3229-39. 2011
    ..These results suggest that relaxin produced during pregnancy may be partly responsible for selective remodeling of PAs during pregnancy through a mechanism involving PPARγ..
  4. pmc Effect of pregnancy and nitric oxide on the myogenic vasodilation of posterior cerebral arteries and the lower limit of cerebral blood flow autoregulation
    Abbie C Chapman
    Neuroscience Graduate Program, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Reprod Sci 20:1046-54. 2013
    ..The shift in the autoregulatory curve to lower pressures during pregnancy is likely protective of ischemic injury during hemorrhage and appears to be independent of NOS. ..
  5. pmc Effect of PPARγ inhibition during pregnancy on posterior cerebral artery function and structure
    Siu Lung Chan
    Department of Neurology, University of Vermont Burlington, VT, USA
    Front Physiol 1:130. 2010
    ..Down-regulation of PPARγ and AT1R in cerebral arteries may be responsible for the lack of effect of PPARγ in cerebral vasculature and may be part of the vascular adaptation to pregnancy...
  6. pmc Effect of pregnancy on autoregulation of cerebral blood flow in anterior versus posterior cerebrum
    Marilyn J Cipolla
    Department of Neurology, University of Vermont, 149 Beaumont Ave, HSRF 416, Burlington, VT 05405, USA
    Hypertension 60:705-11. 2012
    ..These findings suggest that, although pregnancy shifted the cerebral blood flow autoregulatory curve to higher pressures in both the anterior and posterior cortices, it did not protect from edema during acute hypertension...
  7. ncbi request reprint Increased pressure-induced tone in rat parenchymal arterioles vs. middle cerebral arteries: role of ion channels and calcium sensitivity
    Marilyn J Cipolla
    Department of Neurological Sciences, University of Vermont, Burlington, Vermont Department of Pharmacology, University of Vermont, Burlington, Vermont and Department of Obstetrics, Gynecology and Reproductive Sciences, University of Vermont, Burlington, Vermont
    J Appl Physiol (1985) 117:53-9. 2014
    ..Thus increased myogenic tone in PAs appears related to differences in ion channel activity that promotes VSM membrane depolarization but not to a direct sensitization of the contractile apparatus to calcium. ..
  8. pmc Cerebral vascular adaptation to pregnancy and its role in the neurological complications of eclampsia
    Marilyn J Cipolla
    Department of Neurology, Univ of Vermont, 89 Beaumont Ave, Given C454, Burlington, VT 05405, USA
    J Appl Physiol (1985) 110:329-39. 2011
    ....